Tye G. Deering

ScholarGPS® ID: 72314596581272

Affiliation

University of Virginia, Charlottesville, United States

Affiliation History

Field

Pharmacy and Pharmaceutical Sciences

Discipline

Pharmacology and Toxicology

Top Specialties

Cancer | Chemotherapy | Metabolism

Metrics Summary

Publication Count

Predicted Citations

1,767

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Solid tumor treatment via augmentation of bioactive C6 ceramide levels with thermally ablative focused ultrasound (journal article) Thim, E. Andrew \| Fox, Todd \| Deering, Tye \| Vass, Luke R. \| Sheybani, Natasha D. \| Kester, Mark \| Price, Richard J. Drug Delivery and Translational Research, volume 13, issue 12, pages 3145-3153 (2023). 10.1007/s13346-023-01377-w Cite \| Source
Key transcriptional effectors of the pancreatic acinar phenotype and oncogenic transformation (journal article) Azevedo-Pouly, Ana \| Hale, Michael A. \| Swift, Galvin H. \| Hoang, Chinh Q. \| Deering, Tye G. \| Xue, Jumin \| Wilkie, Thomas M. \| Murtaugh, L. Charles \| MacDonald, Raymond J. PLOS ONE, volume 18, issue 10, pages e0291512- (2023). 10.1371/journal.pone.0291512 Cited by (1) \| Cite \| Source
Ceramide Nanoliposomes as Potential Therapeutic Reagents for Asthma (journal article) Sakae, Harumi \| Ogiso, Yuri \| Matsuda, Masaya \| Shimora, Hayato \| Deering, Tye \| Fox, Todd E. \| Kester, Mark \| Nabe, Takeshi \| Kitatani, Kazuyuki Cells, volume 12, issue 4, pages 591- (2023). 10.3390/cells12040591 Cited by (3) \| Cite \| Source
Ceramide nanoliposomes augment the efficacy of venetoclax and cytarabine in models of acute myeloid leukemia (journal article) Khokhlatchev, Andrei V. \| Sharma, Arati \| Deering, Tye G. \| Shaw, Jeremy J. P. \| Costa‐Pinheiro, Pedro \| Golla, Upendarrao \| Annageldiyev, Charyguly \| Cabot, Myles C. \| Conaway, Mark R. \| Tan, Su‐Fern \| ... \| Kester, Mark The FASEB Journal, volume 36, issue 10 (2022). 10.1096/fj.202200765R Cited by (7) \| Cite \| Source
Influence of ceramide on lipid domain stability studied with small-angle neutron scattering: The role of acyl chain length and unsaturation (journal article) DiPasquale, Mitchell \| Deering, Tye G. \| Desai, Dhimant \| Sharma, Arun K. \| Amin, Shantu \| Fox, Todd E. \| Kester, Mark \| Katsaras, John \| Marquardt, Drew \| Heberle, Frederick A. Chemistry and Physics of Lipids, volume 245 (2022). 10.1016/j.chemphyslip.2022.105205 Cited by (9) \| Cite \| Source
Sphingolipid metabolism determines the therapeutic efficacy of nanoliposomal ceramide in acute myeloid leukemia (journal article) Barth, Brian M. \| Wang, Weiyuan \| Toran, Paul T. \| Fox, Todd E. \| Annageldiyev, Charyguly \| Ondrasik, Regina M. \| Keasey, Nicole R. \| Brown, Timothy J. \| Devine, Viola G. \| Sullivan, Emily C. \| ... \| Claxton, David F. Blood Advances, volume 3, issue 17, pages 2598-2603 (2019). 10.1182/bloodadvances.2018021295 Cited by (24) \| Cite \| Source
The Role of Ceramide Structure in Regulating the Stability of Membrane Domains (journal article) Heberle, Frederick A. \| DiPasquale, Mitchell \| Deering, Tye \| Kester, Mark \| Katsaras, John \| Marquardt, Drew Biophysical Journal, volume 116, issue 3, pages 78a- (2019). 10.1016/j.bpj.2018.11.465 Cite \| Source
Ceramide nanoliposomes as a MLKL-dependent, necroptosis-inducing, chemotherapeutic reagent in cancer (journal article) Kitatani, Kazuyuki \| Yamamoto, Yudai \| Zhang, Xuewei \| Deering, Tye \| Kester, Mark \| Yaegashi, Nobuo \| Matsuda, Masaya \| Nabe, Takeshi Proceedings for Annual Meeting of The Japanese Pharmacological Society, volume 92 (2019). 10.1254/jpssuppl.92.0_1-P-099 Cite \| Source
Nanoliposome C6-Ceramide Increases the Anti-tumor Immune Response and Slows Growth of Liver Tumors in Mice (journal article) Li, Guangfu \| Liu, Dai \| Kimchi, Eric T. \| Kaifi, Jussuf T. \| Qi, Xiaoqiang \| Manjunath, Yariswamy \| Liu, Xinjian \| Deering, Tye \| Avella, Diego M. \| Fox, Todd \| ... \| Staveley-O’Carroll, Kevin F. Gastroenterology, volume 154, issue 4, pages 1024-1036.e9 (2018). 10.1053/j.gastro.2017.10.050 Cited by (111) \| Cite \| Source \| Open Access
Ceramide Nanoliposomes as a MLKL-Dependent, Necroptosis-Inducing, Chemotherapeutic Reagent in Ovarian Cancer (journal article) Zhang, Xuewei \| Kitatani, Kazuyuki \| Toyoshima, Masafumi \| Ishibashi, Masumi \| Usui, Toshinori \| Minato, Junko \| Egiz, Mahy \| Shigeta, Shogo \| Fox, Todd \| Deering, Tye \| ... \| Yaegashi, Nobuo Molecular Cancer Therapeutics, volume 17, issue 1, pages 50-59 (2018). 10.1158/1535-7163.MCT-17-0173 Cited by (41) \| Cite \| Source
Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation, and Homeostasis by PTF1A (journal article) Hoang, Chinh Q. \| Hale, Michael A. \| Azevedo-Pouly, Ana C. \| Elsässer, Hans P. \| Deering, Tye G. \| Willet, Spencer G. \| Pan, Fong C. \| Magnuson, Mark A. \| Wright, Christopher V. E. \| Swift, Galvin H. \| MacDonald, Raymond J. Molecular and Cellular Biology, volume 36, issue 24, pages 3033-3047 (2016). 10.1128/MCB.00358-16 Cited by (71) \| Cite \| Source \| Open Access
MIST1 and PTF1 Collaborate in Feed-Forward Regulatory Loops That Maintain the Pancreatic Acinar Phenotype in Adult Mice (journal article) Jiang, Mei \| Azevedo-Pouly, Ana C. \| Deering, Tye G. \| Hoang, Chinh Q. \| DiRenzo, Daniel \| Hess, David A. \| Konieczny, Stephen F. \| Swift, Galvin H. \| MacDonald, Raymond J. Molecular and Cellular Biology, volume 36, issue 23, pages 2945-2955 (2016). 10.1128/MCB.00370-16 Cited by (35) \| Cite \| Source \| Open Access
MIST1 Links Secretion and Stress as both Target and Regulator of the Unfolded Protein Response (journal article) Hess, David A. \| Strelau, Katherine M. \| Karki, Anju \| Jiang, Mei \| Azevedo-Pouly, Ana C. \| Lee, Ann-Hwee \| Deering, Tye G. \| Hoang, Chinh Q. \| MacDonald, Raymond J. \| Konieczny, Stephen F. Molecular and Cellular Biology, volume 36, issue 23, pages 2931-2944 (2016). 10.1128/MCB.00366-16 Cited by (32) \| Cite \| Source \| Open Access
Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia (journal article) Morad, Samy A.F. \| Ryan, Terence E. \| Neufer, P. Darrell \| Zeczycki, Tonya N. \| Davis, Traci S. \| MacDougall, Matthew R. \| Fox, Todd E. \| Tan, Su-Fern \| Feith, David J. \| Loughran, Thomas P. \| ... \| Cabot, Myles C. Journal of Lipid Research, volume 57, issue 7, pages 1231-1242 (2016). 10.1194/jlr.M067389 Cited by (27) \| Cite \| Source \| Open Access
Sphingoproteomics: Proteomic Strategies to Examine Sphingolipid Biology (book chapter) In Bioactive Sphingolipids in Cancer Biology and Therapy Stanley, Bruce A. \| Deering, Tye \| Fox, Todd E. Springer International Publishing (2015) 10.1007/978-3-319-20750-6_16 Cite \| Source
The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis (journal article) Hale, Michael A. \| Swift, Galvin H. \| Hoang, Chinh Q. \| Deering, Tye G. \| Masui, Toshi \| Lee, Youn-Kyoung \| Xue, Jumin \| MacDonald, Raymond J. Development, volume 141, issue 16, pages 3123-3133 (2014). 10.1242/dev.109405 Cited by (84) \| Cite \| Source \| Open Access
Program Specificity for Ptf1a in Pancreas versus Neural Tube Development Correlates with Distinct Collaborating Cofactors and Chromatin Accessibility (journal article) Meredith, David M. \| Borromeo, Mark D. \| Deering, Tye G. \| Casey, Bradford H. \| Savage, Trisha K. \| Mayer, Paul R. \| Hoang, Chinh \| Tung, Kuang-Chi \| Kumar, Manonmani \| Shen, Chengcheng \| ... \| Johnson, Jane E. Molecular and Cellular Biology, volume 33, issue 16, pages 3166-3179 (2013). 10.1128/MCB.00364-13 Cited by (31) \| Cite \| Source \| Open Access
Hemodynamic flow improves rat hepatocyte morphology, function, and metabolic activity in vitro (journal article) Dash, A. \| Simmers, M. B. \| Deering, T. G. \| Berry, D. J. \| Feaver, R. E. \| Hastings, N. E. \| Pruett, T. L. \| LeCluyse, E. L. \| Blackman, B. R. \| Wamhoff, B. R. American Journal of Physiology-Cell Physiology, volume 304, issue 11, pages C1053-C1063 (2013). 10.1152/ajpcell.00331.2012 Cited by (88) \| Cite \| Source \| Open Access
Ptf1a control of Dll1 reveals an alternative to the lateral inhibition mechanism (journal article) Ahnfelt-Rønne, Jonas \| Jørgensen, Mette C. \| Klinck, Rasmus \| Jensen, Jan N. \| Füchtbauer, Ernst-Martin \| Deering, Tye \| MacDonald, Raymond J. \| Wright, Chris V. E. \| Madsen, Ole D. \| Serup, Palle Development, volume 139, issue 23, pages 4492-4492 (2012). 10.1242/dev.090597 Cited by (2) \| Cite \| Source \| Open Access
Induced Mist1 Expression Promotes Remodeling of Mouse Pancreatic Acinar Cells (journal article) Direnzo, Daniel \| Hess, David A. \| Damsz, Barbara \| Hallett, Judy E. \| Marshall, Brett \| Goswami, Chirayu \| Liu, Yunlong \| Deering, Tye \| MacDonald, Raymond J. \| Konieczny, Stephen F. Gastroenterology, volume 143, issue 2, pages 469-480 (2012). 10.1053/j.gastro.2012.04.011 Cited by (56) \| Cite \| Source \| Open Access