Domingos Ng

ScholarGPS® ID: 71601743251085

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Antibody

Metrics Summary

Publication Count

Predicted Citations

361

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Combining regulated and constitutive protein expression significantly boosts protein expression by increasing productivity without affecting CHO cell growth (journal article) Lam, Cynthia \| Carver, Joseph \| Ng, Domingos \| Zhan, Dejin \| Tang, Danming \| Kandamkalam, Thara \| Snedecor, Brad \| Barnard, Gavin \| Shen, Amy \| Misaghi, Shahram Biotechnology Progress, volume 39, issue 3 (2023). 10.1002/btpr.3337 Cited by (1) \| Cite \| Source
Development of a Targeted Integration Chinese Hamster Ovary ( ) Host Directly Targeting Either One or Two Vectors Simultaneously to a Single Locus Using the Cre/Lox System (journal article) Ng, Domingos \| Zhou, Meixia \| Zhan, Dejin \| Yip, Shirley \| Ko, Peggy \| Yim, Mandy \| Modrusan, Zora \| Joly, John \| Snedecor, Brad \| Laird, Michael W. \| Shen, Amy Biotechnology Progress (2021). 10.1002/btpr.3140 Cited by (21) \| Cite \| Source
Maximizing antibody production in a targeted integration host by optimization of subunit gene dosage and position (journal article) Carver, Joe \| Ng, Domingos \| Zhou, Michelle \| Ko, Peggy \| Zhan, Dejin \| Yim, Mandy \| Shaw, David \| Snedecor, Brad \| Laird, Michael W. \| Lang, Steven \| ... \| Hu, Zhilan Biotechnology Progress, volume 36, issue 4 (2020). 10.1002/btpr.2967 Cited by (47) \| Cite \| Source
A strategy to accelerate protein production from a pool of clones in Chinese hamster ovary cells for toxicology studies (journal article) Hu, Zhilan \| Hsu, Wendy \| Pynn, Abby \| Ng, Domingos \| Quicho, Donna \| Adem, Yilma \| Kwong, Zephie \| Mauger, Brad \| Joly, John \| Snedecor, Bradley \| ... \| Shen, Amy Biotechnology Progress, volume 33, issue 6, pages 1449-1455 (2017). 10.1002/btpr.2467 Cited by (26) \| Cite \| Source
An efficient route to bispecific antibody production using single-reactor mammalian co-culture (journal article) Shatz, Whitney \| Ng, Domingos \| Dutina, George \| Wong, Athena W. \| Dunshee, Diana Ronai \| Sonoda, Junichiro \| Shen, Amy \| Scheer, Justin M. mAbs, volume 8, issue 8, pages 1487-1497 (2016). 10.1080/19420862.2016.1234569 Cited by (16) \| Cite \| Source \| Open Access
Decreasing lactate level and increasing antibody production in Chinese Hamster Ovary cells (CHO) by reducing the expression of lactate dehydrogenase and pyruvate dehydrogenase kinases (journal article) Zhou, Meixia \| Crawford, Yongping \| Ng, Domingos \| Tung, Jack \| Pynn, Abigail F.J. \| Meier, Angela \| Yuk, Inn H. \| Vijayasankaran, Natarajan \| Leach, Kimberly \| Joly, John \| ... \| Shen, Amy Journal of Biotechnology, volume 153, issue 1-2, pages 27-34 (2011). 10.1016/j.jbiotec.2011.03.003 Cited by (130) \| Cite \| Source
Identification of IgG1 variants with increased affinity to FcγRIIIa and unaltered affinity to FcγRI and FcRn: Comparison of soluble receptor-based and cell-based binding assays (journal article) Lu, Yanmei \| Vernes, Jean-Michel \| Chiang, Nancy \| Ou, Qinglin \| Ding, Jiabing \| Adams, Camellia \| Hong, Kyu \| Truong, Bao-Tran \| Ng, Domingos \| Shen, Amy \| ... \| Meng, Y. Gloria Journal of Immunological Methods, volume 365, issue 1-2, pages 132-141 (2011). 10.1016/j.jim.2010.12.014 Cited by (27) \| Cite \| Source
Antibodies with enhanced adcc function (patent) Bayer, Robert \| Harris, Reed J. \| Ng, Domingos \| Shen, Amy \| Yu, Marcella Patent Number: 20110003338 (2010) Cite \| Source
Method of producing antibodies with improved function (patent) Joly, John C. \| Lowman, Henry B. \| Ng, Domingos \| Shen, Amy \| Snedecor, Bradley R. Patent Number: 20090208500 (2006) Cite \| Source