Kimberly Stegmaier

ScholarGPS® ID: 71495931656099

Affiliation

Dana-Farber Cancer Institute, Boston, United States

Affiliation History

Field

Medicine

Discipline

Pediatrics

Top Specialties

Metrics Summary

Publication Count

159

Predicted Citations

8,940

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Pharmacological targeting of the cancer epigenome (journal article) Mabe, Nathaniel W. \| Perry, Jennifer A. \| Malone, Clare F. \| Stegmaier, Kimberly Nature Cancer, volume 5, issue 6, pages 844-865 (2024). 10.1038/s43018-024-00777-2 Cited by (1) \| Cite \| Source
The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN- amplified neuroblastoma (journal article) Malone, Clare F. \| Mabe, Nathaniel W. \| Forman, Alexandra B. \| Alexe, Gabriela \| Engel, Kathleen L. \| Chen, Ying-Jiun C. \| Soeung, Melinda \| Salhotra, Silvi \| Basanthakumar, Allen \| Liu, Bin \| ... \| Stegmaier, Kimberly Science Advances, volume 10, issue 22 (2024). 10.1126/sciadv.adm9449 Cite \| Source
STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma (journal article) Prutsch, Nicole \| He, Shuning \| Berezovskaya, Alla \| Durbin, Adam D. \| Dharia, Neekesh V. \| Maher, Kelsey A. \| Matthews, Jamie D. \| Hare, Lucy \| Turner, Suzanne D. \| Stegmaier, Kimberly \| ... \| Zimmerman, Mark W. Cell Reports Medicine, volume 5, issue 3, pages 101472- (2024). 10.1016/j.xcrm.2024.101472 Cite \| Source
The UBE2J2/UBE2K-MARCH5 ubiquitination machinery regulates apoptosis in response to venetoclax in acute myeloid leukemia (journal article) Lin, Shan \| Schneider, Constanze \| Su, Angela H. \| Alexe, Gabriela \| Root, David E. \| Stegmaier, Kimberly Leukemia, volume 38, issue 3, pages 652-656 (2024). 10.1038/s41375-024-02178-x Cited by (1) \| Cite \| Source
DHODH: a promising target in the treatment of T-cell acute lymphoblastic leukemia (journal article) Sexauer, Amy N. \| Alexe, Gabriela \| Gustafsson, Karin \| Zanetakos, Elizabeth \| Milosevic, Jelena \| Ayres, Mary \| Gandhi, Varsha \| Pikman, Yana \| Stegmaier, Kimberly \| Sykes, David B. Blood Advances, volume 7, issue 21, pages 6685-6701 (2023). 10.1182/bloodadvances.2023010337 Cite \| Source
Identifying Targeted Therapies for CBFA2T3 - GLIS2 Acute Myeloid Leukemia (journal article) Gonzales, Fanny \| Lin, Shan \| Khalid, Delan \| Ellegast, Jana M \| Alexe, Gabriela \| Stegmaier, Kimberly Blood, volume 142, issue Supplement 1, pages 4174-4174 (2023). 10.1182/blood-2023-187187 Cite \| Source
Combining Menin and MEK Inhibition to Target Poor Prognostic KMT2A -Rearranged RAS Pathway-Mutant Acute Leukemia (journal article) Scheidegger, Nastassja \| Alexe, Gabriela \| Khalid, Delan \| Ries, Rhonda E \| Wang, Jim \| Alonzo, Todd A. \| Perry, Jennifer \| Armstrong, Scott A \| Meshinchi, Soheil \| Pikman, Yana \| Stegmaier, Kimberly Blood, volume 142, issue Supplement 1, pages 166-166 (2023). 10.1182/blood-2023-185561 Cited by (2) \| Cite \| Source
Functional Dissection of Cellular Programs to Uncover Novel Gene Dependencies in AML (journal article) Ellegast, Jana M \| Alexe, Gabriela \| Baniya, Subha \| Hamze, Amanda \| Taillon, Audrey \| Adane, Biniam \| Saur Conway, Amy \| Zhang, Tinghu \| Gray, Nathanael S \| Armstrong, Scott A \| Stegmaier, Kimberly Blood, volume 142, issue Supplement 1, pages 1393-1393 (2023). 10.1182/blood-2023-189304 Cite \| Source
The UBE2J2/UBE2K-MARCH5 Ubiquitination Machinery Regulates Apoptosis in Response to Venetoclax in Acute Myeloid Leukemia (journal article) Schneider, Constanze \| Lin, Shan \| Su, Angela H \| Alexe, Gabriela \| Stegmaier, Kimberly Blood, volume 142, issue Supplement 1, pages 2785-2785 (2023). 10.1182/blood-2023-182312 Cite \| Source
Phase 2 trial of palbociclib and ganitumab in patients with relapsed Ewing sarcoma (journal article) Shulman, David S. \| Merriam, Priscilla \| Choy, Edwin \| Guenther, Lillian M. \| Cavanaugh, Kerri L. \| Kao, Pei‐Chi \| Posner, Andrew \| Bhushan, Ketki \| Fairchild, Grace \| Barker, Emma \| ... \| DuBois, Steven G. Cancer Medicine, volume 12, issue 14, pages 15207-15216 (2023). 10.1002/cam4.6208 Cited by (6) \| Cite \| Source
Mitochondrial fusion is a therapeutic vulnerability of acute myeloid leukemia (journal article) Larrue, Clement \| Mouche, Sarah \| Lin, Shan \| Simonetta, Federico \| Scheidegger, Nastassja K. \| Poulain, Laury \| Birsen, Rudy \| Sarry, Jean-Emmanuel \| Stegmaier, Kimberly \| Tamburini, Jerome Leukemia, volume 37, issue 4, pages 765-775 (2023). 10.1038/s41375-023-01835-x Cited by (10) \| Cite \| Source
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS–FLI to promote Ewing sarcoma (journal article) Lu, Diana Y. \| Ellegast, Jana M. \| Ross, Kenneth N. \| Malone, Clare F. \| Lin, Shan \| Mabe, Nathaniel W. \| Dharia, Neekesh V. \| Meyer, Ashleigh \| Conway, Amy \| Su, Angela H. \| ... \| Stegmaier, Kimberly Nature Cell Biology (2023). 10.1038/s41556-022-01059-8 Cited by (6) \| Cite \| Source
Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors (journal article) Malone, Clare F. \| Kim, Minjee \| Alexe, Gabriela \| Engel, Kathleen \| Forman, Alexandra B. \| Robichaud, Amanda \| Conway, Amy Saur \| Goodale, Amy \| Meyer, Ashleigh \| Khalid, Delan \| ... \| Stegmaier, Kimberly Cancer Research, volume 83, issue 2, pages 285-300 (2023). 10.1158/0008-5472.CAN-21-4309 Cited by (4) \| Cite \| Source
P410: COMBINING MENIN AND MEK INHIBITION TO TREAT CHILDREN WITH POOR PROGNOSTIC KMT2A-R RAS-MUTANT ACUTE LEUKEMIA (journal article) Scheidegger, Nastassja \| Alexe, Gabriela \| Khalid, Delan \| Perry, Jennifer \| Armstrong, Scott \| Pikman, Yana \| Stegmaier, Kimberly HemaSphere, volume 7, issue S3, pages e0491723- (2023). 10.1097/01.HS9.0000968548.04917.23 Cite \| Source
Adverse prognostic impact of the loss of STAG2 protein expression in patients with newly diagnosed localised Ewing sarcoma: A report from the Children’s Oncology Group (journal article) Shulman, David S. \| Chen, Sonja \| Hall, David \| Nag, Anwesha \| Thorner, Aaron R. \| Lessnick, Stephen L. \| Stegmaier, Kimberly \| Janeway, Katherine A. \| DuBois, Steven G. \| Krailo, Mark D. \| ... \| Crompton, Brian D. British Journal of Cancer, volume 127, issue 12, pages 2220-2226 (2022). 10.1038/s41416-022-01977-2 Cited by (10) \| Cite \| Source
Breaking the Pump: Targeting the Sodium-Potassium Pump As a Therapeutic Strategy in Acute Myeloid Leukemia (journal article) Schneider, Constanze \| Spaink, Hermes \| Alexe, Gabriela \| Dharia, Neekesh V. \| Meyer, Ashleigh \| Khalid, Delan \| Scheich, Sebastian \| Häupl, Björn \| Staudt, Louis M. \| Oellerich, Thomas \| Stegmaier, Kimberly Blood, volume 140, issue Supplement 1, pages 4936-4937 (2022). 10.1182/blood-2022-168226 Cite \| Source
DHODH: A Promising New Therapeutic Target in Pediatric T-ALL (journal article) Sexauer, Amy N \| Alexe, Gabriela \| Gandhi, Varsha \| Stegmaier, Kimberly \| Sykes, David Blood, volume 140, issue Supplement 1, pages 7795-7797 (2022). 10.1182/blood-2022-167569 Cite \| Source
Mechanisms of the CBFA2T3-GLIS2 Fusion in AML Maintenance (journal article) Gonzales, Fanny C \| Lin, Shan \| Khalid, Delan \| Ellegast, Jana M \| Alexe, Gabriela \| Stegmaier, Kimberly Blood, volume 140, issue Supplement 1, pages 5864-5865 (2022). 10.1182/blood-2022-166664 Cite \| Source
Transcriptional Plasticity Drives Leukemia Immune Escape (journal article) Eagle, Kenneth \| Harada, Taku \| Kalfon, Jérémie \| Perez, Monika W. \| Heshmati, Yaser \| Ewers, Jazmin \| Koren, Jošt Vrabič \| Dempster, Joshua M. \| Kugener, Guillaume \| Paralkar, Vikram R. \| ... \| Pimkin, Maxim Blood Cancer Discovery, volume 3, issue 5, pages 394-409 (2022). 10.1158/2643-3230.BCD-21-0207 Cited by (9) \| Cite \| Source
Mitochondrial Dysfunction Is a Driver of SP-2509 Drug Resistance in Ewing Sarcoma (journal article) Tokarsky, E. John \| Crow, Jesse C. \| Guenther, Lillian M. \| Sherman, John \| Taslim, Cenny \| Alexe, Gabriela \| Pishas, Kathleen I. \| Rask, Galen \| Justis, Blake S. \| Kasumova, Ana \| ... \| Theisen, Emily R. Molecular Cancer Research, volume 20, issue 7, pages 1035-1046 (2022). 10.1158/1541-7786.MCR-22-0027 Cited by (4) \| Cite \| Source

Title	Investigators	Year	Cost	Agency
Integrating Transforming Approaches to Identify and Target New Vulnerabilities in Cancer	Stegmaier, Kimberly	2020	$1,091,957	NATIONAL CANCER INSTITUTE
Dissecting the Pathogenesis of Ewing Sarcoma with Integrative Genomics	Stegmaier, Kimberly \| Sweet-Cordero, Eric Alejandro	2020	$479,795	NATIONAL CANCER INSTITUTE
Dissecting the Pathogenesis of Ewing Sarcoma with Integrative Genomics	Stegmaier, Kimberly \| Sweet-Cordero, Eric Alejandro	2019	$384,651	NATIONAL CANCER INSTITUTE
Targeting BET-bromodomains in neuroblastoma	Stegmaier, Kimberly \| Weiss, William A	2019	$641,224	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Integrating Transforming Approaches to Identify and Target New Vulnerabilities in Cancer	Stegmaier, Kimberly	2019	$1,015,049	NATIONAL CANCER INSTITUTE
Dissecting the Pathogenesis of Ewing Sarcoma with Integrative Genomics	Stegmaier, Kimberly \| Sweet-Cordero, Eric Alejandro	2019	$119,844	NATIONAL CANCER INSTITUTE
Targeting SYK Kinase in AML	Stegmaier, Kimberly	2018	$90,131	NATIONAL CANCER INSTITUTE
Dissecting the Pathogenesis of Ewing Sarcoma with Integrative Genomics	Stegmaier, Kimberly \| Sweet-Cordero, Eric Alejandro	2018	$40,302	NATIONAL CANCER INSTITUTE
Dissecting the Pathogenesis of Ewing Sarcoma with Integrative Genomics	Stegmaier, Kimberly \| Sweet-Cordero, Eric Alejandro	2018	$228,600	NATIONAL CANCER INSTITUTE
Project 3: Delineating and Drugging the Core Transcriptional Circuitry in Ewing Sarcoma	Stegmaier, Kimberly	2018	$2,499,136	NATIONAL CANCER INSTITUTE
Administrative Core	Stegmaier, Kimberly	2018	$671,070	NATIONAL CANCER INSTITUTE
The Center for Therapeutic Targeting of EWS-oncoproteins	Armstrong, Scott A \| Stegmaier, Kimberly	2018	$12,500,000	NATIONAL CANCER INSTITUTE
Targeting SYK Kinase in AML	Stegmaier, Kimberly	2018	$348,122	NATIONAL CANCER INSTITUTE
Integrating Transforming Approaches to Identify and Target New Vulnerabilities in Cancer	Stegmaier, Kimberly	2018	$1,046,441	NATIONAL CANCER INSTITUTE
Targeting BET-bromodomains in neuroblastoma	Stegmaier, Kimberly \| Weiss, William A	2018	$651,177	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Dissecting the Pathogenesis of Ewing Sarcoma with Integrative Genomics	Stegmaier, Kimberly \| Sweet-Cordero, Eric Alejandro	2018	$396,547	NATIONAL CANCER INSTITUTE
Integrating Transforming Approaches to Identify and Target New Vulnerabilities in Cancer	Stegmaier, Kimberly	2017	$1,046,441	NATIONAL CANCER INSTITUTE
Dissecting the Pathogenesis of Ewing Sarcoma with Integrative Genomics	Stegmaier, Kimberly \| Sweet-Cordero, Eric Alejandro	2017	$228,600	NATIONAL CANCER INSTITUTE
Targeting SYK Kinase in AML	Stegmaier, Kimberly	2017	$334,016	NATIONAL CANCER INSTITUTE
Targeting BET-bromodomains in neuroblastoma	Stegmaier, Kimberly \| Weiss, William A	2017	$675,172	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Dissecting the Pathogenesis of Ewing Sarcoma with Integrative Genomics	Stegmaier, Kimberly \| Sweet-Cordero, Eric Alejandro	2017	$396,547	NATIONAL CANCER INSTITUTE
Integrating Transforming Approaches to Identify and Target New Vulnerabilities in Cancer	Stegmaier, Kimberly	2016	$1,046,441	NATIONAL CANCER INSTITUTE
Targeting BET-bromodomains in neuroblastoma	Stegmaier, Kimberly \| Weiss, WILLIAM A (contact)	2016	$669,055	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Validating Syk as a Target for AML Therapy	Stegmaier, Kimberly	2015	$387,731	NATIONAL CANCER INSTITUTE
Targeting BET-bromodomains in neuroblastoma	Stegmaier, Kimberly \| Weiss, WILLIAM A (contact)	2015	$698,744	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Validating Syk as a Target for AML Therapy	Stegmaier, Kimberly	2014	$387,775	NATIONAL CANCER INSTITUTE
Targeting the ETS Transcription Factor Rearrangement EWS/FLI in Ewing's Sarcoma	Kung, ANDREW L (contact) \| Stegmaier, Kimberly	2013	$42,438	NATIONAL INSTITUTE ON DRUG ABUSE
Validating Syk as a Target for AML Therapy	Stegmaier, Kimberly	2013	$331,098	NATIONAL CANCER INSTITUTE
Targeting the ETS Transcription Factor Rearrangement EWS/FLI in Ewing's Sarcoma	Kung, ANDREW L (contact) \| Stegmaier, Kimberly	2012	$43,750	NATIONAL INSTITUTE ON DRUG ABUSE
Validating Syk as a Target for AML Therapy	Stegmaier, Kimberly	2012	$352,231	NATIONAL CANCER INSTITUTE
Validating Syk as a Target for AML Therapy	Stegmaier, Kimberly	2011	$352,231	NATIONAL CANCER INSTITUTE
Validating Syk as a Target for AML Therapy	Stegmaier, Kimberly	2010	$362,088	NATIONAL CANCER INSTITUTE
Validating Syk as a Target for AML Therapy	Stegmaier, Kimberly	2009	$357,937	NATIONAL CANCER INSTITUTE
Chemical Genomics Approach to Leukemia Differentiation	Stegmaier, Kimberly	2007	$135,837	NATIONAL CANCER INSTITUTE
Chemical Genomics Approach to Leukemia Differentiation	Stegmaier, Kimberly	2006	$135,837	NATIONAL CANCER INSTITUTE
Chemical Genomics Approach to Leukemia Differentiation	Stegmaier, Kimberly	2005	$135,837	NATIONAL CANCER INSTITUTE
Chemical Genomics Approach to Leukemia Differentiation	Stegmaier, Kimberly	2004	$135,837	NATIONAL CANCER INSTITUTE
Chemical Genomics Approach to Leukemia Differentiation	Stegmaier, Kimberly	2003	$135,837	NATIONAL CANCER INSTITUTE