Christopher J. Molloy

ScholarGPS® ID: 69895092044025

Affiliation
Janssen Pharmaceutica
Affiliation History

Field
Pharmacy and Pharmaceutical Sciences
Discipline
Pharmacology and Toxicology
Top Specialties
Medicinal Chemistry | Neutrophil | Cancer | Crystal Structure
Metrics Summary
Publication Count
32
Predicted Citations
1,756
Predicted h-index
20
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
You must register and claim your profile to add or remove publications from it.
... publications
FILTER BY:
Year
Type
Specialty
Affiliations
Access
Co-Authors
Add
Delete
Method of inhibiting C-KIT kinase (patent)
Illig, Carl R. | Ballentine, Shelley K. | Chen, Jinsheng | Meegalla, Sanath K. | Rudolph, M. Jonathan | Wall, Mark J. | Wilson, Kenneth J. | Desjarlais, Renee Louise | Manthey, Carl M. | Molloy, Christopher J.
Patent Number: 9526731 (2016)
Cite | Source
Method of inhibiting C-KIT kinase (patent)
Illig, Carl R. | Ballentine, Shelley K. | Chen, Jinsheng | Meegalla, Sanath K. | Rudolph, M. Jonathan | Wall, Mark J. | Wilson, Kenneth J. | Desjarlais, Renee Louise | Manthey, Carl M. | Molloy, Christopher J.
Patent Number: 8933091 (2015)
Cite | Source
Method of inhibiting C-KIT kinase (patent)
Illig, Carl R. | Balltentine, Shelley K. | Chen, Jinsheng | Meegalla, Sanath K. | Rudolph, M. Jonathan | Wall, Mark J. | Wilson, Kenneth J. | DesJarlais, Renee L. | Manthey, Carl L. | Molloy, Christopher J.
Patent Number: 8697716 (2014)
Cite | Source
Enhancement of kinase selectivity in a potent class of arylamide FMS inhibitors (journal article)
Illig, Carl R. | Manthey, Carl L. | Meegalla, Sanath K. | Wall, Mark J. | Chen, Jinsheng | Wilson, Kenneth J. | DesJarlais, Renee L. | Ballentine, Shelley K. | Schubert, Carsten | Crysler, Carl S. | ... | Tomczuk, Bruce E.
Bioorganic & Medicinal Chemistry Letters, volume 23, issue 23, pages 6363-6369 (2013).
10.1016/j.bmcl.2013.09.061
Cited by (3) | Cite | Source
Design and synthesis of polyethylene glycol-modified biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s (journal article)
Subasinghe, Nalin L. | Khalil, Ehab | Travins, Jeremy M. | Ali, Farah | Ballentine, Shelley K. | Hufnagel, Heather R. | Pan, Wenxi | Leonard, Kristi | Bone, Roger F. | Soll, Richard M. | ... | Gaul, Michael D.
Bioorganic & Medicinal Chemistry Letters, volume 22, issue 16, pages 5303-5307 (2012).
10.1016/j.bmcl.2012.06.030
Cited by (12) | Cite | Source
The discovery of novel cyclohexylamide CCR2 antagonists (journal article)
Lanter, James C. | Markotan, Thomas P. | Zhang, Xuqing | Subasinghe, Nalin | Kang, Fu-An | Hou, Cuifen | Singer, Monica | Opas, Evan | McKenney, Sandra | Crysler, Carl | ... | Sui, Zhihua
Bioorganic & Medicinal Chemistry Letters, volume 21, issue 24, pages 7496-7501 (2011).
10.1016/j.bmcl.2011.09.113
Cited by (9) | Cite | Source
Optimization of a Potent Class of Arylamide Colony-Stimulating Factor-1 Receptor Inhibitors Leading to Anti-inflammatory Clinical Candidate 4-Cyano- N -[2-(1-cyclohexen-1-yl)-4-[1-[(dimethylamino)acetyl]-4-piperidinyl]phenyl]-1 H -imidazole-2-carboxamide (journal article)
Illig, Carl R. | Manthey, Carl L. | Wall, Mark J. | Meegalla, Sanath K. | Chen, Jinsheng | Wilson, Kenneth J. | Ballentine, Shelley K. | DesJarlais, Renee L. | Schubert, Carsten | Crysler, Carl S. | ... | Tomczuk, Bruce E.
Journal of Medicinal Chemistry, volume 54, issue 22, pages 7860-7883 (2011).
10.1021/jm200900q
Cited by (32) | Cite | Source
Reducing ion channel activity in a series of 4-heterocyclic arylamide FMS inhibitors (journal article)
Wilson, Kenneth J. | Illig, Carl R. | Chen, Jinsheng | Wall, Mark J. | Ballentine, Shelley K. | DesJarlais, Renee L. | Chen, Yanmin | Schubert, Carsten | Donatelli, Robert | Petrounia, Ioanna | ... | Meegalla, Sanath K.
Bioorganic & Medicinal Chemistry Letters, volume 20, issue 13, pages 3925-3929 (2010).
10.1016/j.bmcl.2010.05.013
Cited by (11) | Cite | Source
Class of arylamide compounds useful as inhibitors of c-fms kinase (patent)
Illig, Carl R. | Ballentine, Shelley K. | Chen, Jinsheng | Meegalla, Sanath | Rudolph, Jonathan | Wall, Mark J. | Wilson, Kenneth J. | DesJarlais, Renee | Manthey, Carl L. | Flores, Christopher M. | Molloy, Christopher J.
Patent Number: 7705042 (2010)
Cited by (4) | Cite | Source
Inhibitors of c-fms kinase (patent)
Illig, Carl R. | Ballentine, Shelley K. | Chen, Jinsheng | Meegalla, Sanath K. | Rudolph, M. Jonathan | Wall, Mark J. | Wilson, Kenneth J. | Desjarlais, Renee L. | Manthey, Carl L. | Flores, Christopher | Molloy, Christopher J.
Patent Number: 7662837 (2010)
Cited by (19) | Cite | Source
Inhibitors of c-fms kinase (patent)
Illig, Carl R. | Ballentine, Shelley K. | Chen, Jinsheng | Meegalla, Sanath K. | Rudolph, M. Jonathan | Wall, Mark J. | Wilson, Kenneth J. | Desjarlais, Renee L. | Manthey, Carl L. | Flores, Christopher | Molloy, Christopher J.
Patent Number: 7645755 (2010)
Cited by (23) | Cite | Source
Structure-based optimization of a potent class of arylamide FMS inhibitors (journal article)
Meegalla, Sanath K. | Wall, Mark J. | Chen, Jinsheng | Wilson, Kenneth J. | Ballentine, Shelley K. | DesJarlais, Renee L. | Schubert, Carsten | Crysler, Carl S. | Chen, Yanmin | Molloy, Christopher J. | ... | Illig, Carl R.
Bioorganic & Medicinal Chemistry Letters, volume 18, issue 12, pages 3632-3637 (2008).
10.1016/j.bmcl.2008.04.059
Cited by (30) | Cite | Source
Carboxylic acid bioisosteres acylsulfonamides, acylsulfamides, and sulfonylureas as novel antagonists of the CXCR2 receptor (journal article)
Winters, Michael P. | Crysler, Carl | Subasinghe, Nalin | Ryan, Declan | Leong, Lynette | Zhao, Shuyuan | Donatelli, Robert | Yurkow, Edward | Mazzulla, Marie | Boczon, Lisa | ... | Tomczuk, Bruce
Bioorganic & Medicinal Chemistry Letters, volume 18, issue 6, pages 1926-1930 (2008).
10.1016/j.bmcl.2008.01.127
Cited by (27) | Cite | Source
Synthesis and evaluation of novel 3,4,6-substituted 2-quinolones as FMS kinase inhibitors (journal article)
Wall, Mark J. | Chen, Jinsheng | Meegalla, Sanath | Ballentine, Shelley K. | Wilson, Kenneth J. | DesJarlais, Renee L. | Schubert, Carsten | Chaikin, Margery A. | Crysler, Carl | Petrounia, Ioanna P. | ... | Illig, Carl R.
Bioorganic & Medicinal Chemistry Letters, volume 18, issue 6, pages 2097-2102 (2008).
10.1016/j.bmcl.2008.01.088
Cited by (47) | Cite | Source
Biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s (journal article)
Travins, Jeremy M. | Ali, Farah | Huang, Hui | Ballentine, Shelley K. | Khalil, Ehab | Hufnagel, Heather R. | Pan, Wenxi | Gushue, Joan | Leonard, Kristi | Bone, Roger F. | ... | Subasinghe, Nalin L.
Bioorganic & Medicinal Chemistry Letters, volume 18, issue 5, pages 1603-1606 (2008).
10.1016/j.bmcl.2008.01.064
Cited by (17) | Cite | Source
Discovery of novel FMS kinase inhibitors as anti-inflammatory agents (journal article)
Illig, Carl R. | Chen, Jinsheng | Wall, Mark J. | Wilson, Kenneth J. | Ballentine, Shelley K. | Rudolph, M. Jonathan | DesJarlais, Renee L. | Chen, Yanmin | Schubert, Carsten | Petrounia, Ioanna | ... | Meegalla, Sanath K.
Bioorganic & Medicinal Chemistry Letters, volume 18, issue 5, pages 1642-1648 (2008).
10.1016/j.bmcl.2008.01.059
Cited by (44) | Cite | Source
A novel series of arylsulfonylthiophene-2-carboxamidine inhibitors of the complement component C1s (journal article)
Subasinghe, Nalin L. | Travins, Jeremy M. | Ali, Farah | Huang, Hui | Ballentine, Shelley K. | Marugán, Juan José | Khalil, Ehab | Hufnagel, Heather R. | Bone, Roger F. | DesJarlais, Renee L. | ... | Tomczuk, Bruce E.
Bioorganic & Medicinal Chemistry Letters, volume 16, issue 8, pages 2200-2204 (2006).
10.1016/j.bmcl.2006.01.036
Cited by (15) | Cite | Source
Benzodiazepinedione inhibitors of the Hdm2:p53 complex suppress human tumor cell proliferation in vitro and sensitize tumors to doxorubicin in vivo (journal article)
Koblish, Holly K. | Zhao, Shuyuan | Franks, Carol F. | Donatelli, Robert R. | Tominovich, Rose M. | LaFrance, Louis V. | Leonard, Kristi A. | Gushue, Joan M. | Parks, Daniel J. | Calvo, Raul R. | ... | Maroney, Anna C.
Molecular Cancer Therapeutics, volume 5, issue 1, pages 160-169 (2006).
10.1158/1535-7163.MCT-05-0199
Cited by (146) | Cite | Source | Open Access
A functional radioreceptor assay of alpha-V-beta-3 (αvβ3) inhibitors in plasma: Application as an ex vivo pharmacodynamic model (journal article)
Chaikin, Margery A. | Marugan, Júan José | De Vries, Gerald W. | Baciu, Peter | Edelman, Jeffrey | Ni, Ming | Tomczuk, Bruce E. | Pan, Wenxi | Guo, Zihong | Anaclerio, Beth | ... | Manthey, Carl L.
Journal of Biochemical and Biophysical Methods, volume 65, issue 2-3, pages 107-120 (2005).
10.1016/j.jbbm.2005.10.004
Cited by (1) | Cite | Source
Discovery and Cocrystal Structure of Benzodiazepinedione HDM2 Antagonists That Activate p53 in Cells (journal article)
Grasberger, Bruce L. | Lu, Tianbao | Schubert, Carsten | Parks, Daniel J. | Carver, Theodore E. | Koblish, Holly K. | Cummings, Maxwell D. | LaFrance, Louis V. | Milkiewicz, Karen L. | Calvo, Raul R. | ... | Bone, Roger F.
Journal of Medicinal Chemistry, volume 48, issue 4, pages 909-912 (2005).
10.1021/jm049137g
Cited by (393) | Cite | Source