Lawrence De Garavilla

ScholarGPS® ID: 69869505320675

Affiliation

Louisiana State University Health Sciences Center New Orleans, New Orleans, United States

Affiliation History

Field

Life Sciences

Discipline

Physiology

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

2,338

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Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Duodenases are a small subfamily of ruminant intestinal serine proteases that have undergone a remarkable diversification in cleavage specificity (journal article) Fu, Zhirong \| Akula, Srinivas \| Qiao, Chang \| Ryu, Jinhye \| Chahal, Gurdeep \| de Garavilla, Lawrence \| Kervinen, Jukka \| Thorpe, Michael \| Hellman, Lars PLOS ONE, volume 16, issue 5, pages e0252624- (2021). 10.1371/journal.pone.0252624 Cited by (6) \| Cite \| Source
Extended Cleavage Specificities of Rabbit and Guinea Pig Mast Cell Chymases: Two Highly Specific Leu-Ases (journal article) Zhongwei, Yuan \| Akula, Srinivas \| Fu, Zhirong \| de Garavilla, Lawrence \| Kervinen, Jukka \| Thorpe, Michael \| Hellman, Lars International Journal of Molecular Sciences, volume 20, issue 24, pages 6340- (2019). 10.3390/ijms20246340 Cited by (7) \| Cite \| Source
Extended cleavage specificity of sheep mast cell protease-2: A classical chymase with preference to aromatic P1 substrate residues (journal article) Fu, Zhirong \| Akula, Srinivas \| Thorpe, Michael \| Chahal, Gurdeep \| de Garavilla, Lawrence \| Kervinen, Jukka \| Hellman, Lars Developmental & Comparative Immunology, volume 92 (2019). 10.1016/j.dci.2018.11.019 Cited by (4) \| Cite \| Source
Extended cleavage specificities of mast cell proteases 1 and 2 from golden hamster: Classical chymase and an elastolytic protease comparable to rat and mouse MCP-5 (journal article) Thorpe, Michael \| Fu, Zhirong \| Albat, Emanuelle \| Akula, Srinivas \| de Garavilla, Lawrence \| Kervinen, Jukka \| Hellman, Lars PLOS ONE, volume 13, issue 12, pages e0207826- (2018). 10.1371/journal.pone.0207826 Cited by (7) \| Cite \| Source
Extended cleavage specificity of human neutrophil cathepsin G: A low activity protease with dual chymase and tryptase-type specificities (journal article) Thorpe, Michael \| Fu, Zhirong \| Chahal, Gurdeep \| Akula, Srinivas \| Kervinen, Jukka \| de Garavilla, Lawrence \| Hellman, Lars PLOS ONE, volume 13, issue 4, pages e0195077- (2018). 10.1371/journal.pone.0195077 Cited by (31) \| Cite \| Source \| Open Access
Highly Selective Cleavage of Cytokines and Chemokines by the Human Mast Cell Chymase and Neutrophil Cathepsin G (journal article) Fu, Zhirong \| Thorpe, Michael \| Alemayehu, Rahel \| Roy, Ananya \| Kervinen, Jukka \| de Garavilla, Lawrence \| Åbrink, Magnus \| Hellman, Lars The Journal of Immunology, volume 198, issue 4, pages 1474-1483 (2017). 10.4049/jimmunol.1601223 Cited by (59) \| Cite \| Source
Method of treating asthma (patent) Maryanoff, Bruce E. \| Powell, Eugene \| de Garavilla, Lawrence \| Hawkins, Michael J. \| Greco, Michael N. Patent Number: 8546358 (2013) Cite \| Source
Phosphonic acid compounds as inhibitors of serine proteases (patent) Nilsen, Christopher Norman \| Walker, Donald Gilmore \| Powell, Eugene \| Almond,, Harold R. \| Sorgi, Kirk Leonard \| de Garavilla, Lawrence \| Hawkins, Michael J. \| Humora, Michael J. \| Greco, Michael N. \| Patel, Mitul N. \| ... \| Qian, Yun Patent Number: 8497373 (2013) Cite \| Source
OP0184 High Resolution Micro-Computerized Tomography Imaging as a Translational Tool to Quantitatively Assess Bone Damage in a Mouse Model of Collagen-Induced Arthritis in Mice: Disease Severity and Time-Course of Bone Changes (journal article) de Garavilla, L. \| Acton, P. \| Lubomirski, M. \| Malaviya, R. \| Shen, F. \| Shah, N. \| Vasquez, S. \| Yoder, V. \| Small, D. \| Weinstein, D. \| Kilgore, K. Annals of the Rheumatic Diseases, volume 72, issue Suppl 3, pages A115.1-A115 (2013). 10.1136/annrheumdis-2013-eular.389 Cite \| Source
THU0085 Effect of CSF-1R Kinase Inhibitor on FDG PET, MMP Optical, and Microct Imaging in a Rat SCW Model of Rheumatoid Arthritis: Use of Functional and Structural Imaging as Translation Tools (journal article) de Garavilla, L. \| Manthey, C. \| Yurkow, E. \| Zhou, Z. \| Cotto, C. \| Meegalla, S. \| Wilson, K. \| Wall, M. \| Chen, J. \| Ballentine, S. \| ... \| Acton, P. Annals of the Rheumatic Diseases, volume 72, issue Suppl 3, pages A191.4-A192 (2013). 10.1136/annrheumdis-2013-eular.613 Cite \| Source
Phosphonic acid compounds as inhibitors of serine proteases (patent) Nilsen, Christopher Norman \| Walker, Donald Gilmore \| Powell, Eugene \| Almond,, Harold R. \| Sorgi, Kirk Leonerd \| de Garavilla, Lawrence \| Hawkins, Michael J. \| Humora, Michael J. \| Greco, Michael N. \| Patel, Mitul N. \| ... \| Qian, Yun Patent Number: 8394804 (2013) Cite \| Source
Direct Evidence for Intrarenal Chymase-Dependent Angiotensin II Formation on the Diabetic Renal Microvasculature (journal article) Park, Sungmi \| Bivona, Benjamin J. \| Ford, Stephen M. \| Xu, Sen \| Kobori, Hiroyuki \| de Garavilla, Lawrence \| Harrison-Bernard, Lisa M. Hypertension, volume 61, issue 2, pages 465-471 (2013). 10.1161/HYPERTENSIONAHA.111.202424 Cited by (26) \| Cite \| Source \| Open Access
Enhanced vascular chymase-dependent conversion of endothelin in the diabetic kidney. (journal article) Harrison-Bernard, Lisa M \| de Garavilla, Lawrence \| Bivona, Benjamin J The Ochsner journal, volume 13, issue 1 (2013). Cited by (3) \| Cite
The role of the epithelium in chronic inflammatory airway disease (journal article) Dudas, Paul L. \| de Garavilla, Lawrence \| Lundblad, Lennart K.A. \| Knight, Darryl A. Pulmonary Pharmacology & Therapeutics, volume 25, issue 6, pages 413-414 (2012). 10.1016/j.pupt.2012.10.005 Cited by (2) \| Cite \| Source
Proteases and Fibrosis (book chapter) In Proteases and Their Receptors in Inflammation Heightman, Melissa \| Ort, Tatiana \| de Garavilla, Lawrence \| Kilgore, Ken \| Laurent, Geoffrey J. Springer Basel (2011) 10.1007/978-3-0348-0157-7_7 Cite \| Source
Reduction of intravenously administered nanoparticulate-formulation-induced adverse physiological reactions (patent) de Garavilla, Lawrence \| Liversidge, Elaine \| Liversidge, Gary G. Patent Number: RE41884 (2010) Cited by (27) \| Cite \| Source
Potency variation of small-molecule chymase inhibitors across species (journal article) Kervinen, Jukka \| Crysler, Carl \| Bayoumy, Shariff \| Abad, Marta C. \| Spurlino, John \| Deckman, Ingrid \| Greco, Michael N. \| Maryanoff, Bruce E. \| de Garavilla, Lawrence Biochemical Pharmacology, volume 80, issue 7, pages 1033-1041 (2010). 10.1016/j.bcp.2010.06.014 Cited by (24) \| Cite \| Source
Thrombin and trypsin directly activate vagal C-fibres in mouse lung via protease-activated receptor-1 (journal article) Kwong, Kevin \| Nassenstein, Christina \| De Garavilla, Lawrence \| Meeker, Sonya \| Undem, Bradley J. The Journal of Physiology, volume 588, issue 7, pages 1171-1177 (2010). 10.1113/jphysiol.2009.181669 Cited by (19) \| Cite \| Source \| Open Access
Dual Inhibition of Cathepsin G and Chymase Is Effective in Animal Models of Pulmonary Inflammation (journal article) Maryanoff, Bruce E. \| de Garavilla, Lawrence \| Greco, Michael N. \| Haertlein, Barbara J. \| Wells, Grace I. \| Andrade-Gordon, Patricia \| Abraham, William M. American Journal of Respiratory and Critical Care Medicine, volume 181, issue 3, pages 247-253 (2010). 10.1164/rccm.200904-0627OC Cited by (53) \| Cite \| Source
Cooperative antithrombotic effect from the simultaneous inhibition of thrombin and factor Xa (journal article) Giardino, Edward C \| Haertlein, Barbara J \| de Garavilla, Lawrence \| Costanzo, Michael J \| Damiano, Bruce P \| Andrade-Gordon, Patricia \| Maryanoff, Bruce E Blood Coagulation & Fibrinolysis, volume 21, issue 2, pages 128-134 (2010). 10.1097/MBC.0b013e3283358100 Cited by (24) \| Cite \| Source