Charles E. Chalfant

ScholarGPS® ID: 69457540647126

Affiliation
University of South Florida, Tampa, United States
Affiliation History

Field
Life Sciences
Discipline
Molecular and Cell Biology
Top Specialties
Lipid | Alternative Splicing | Cancer | Protein Kinase | Insulin | Phospholipase A2 | Diabetes | Protein Phosphatase | Skeletal Muscle | Eicosanoid | Glucose | Hypertension | Macrophage | Wound Healing | Biosynthesis
Metrics Summary
Publication Count
172
Predicted Citations
10,996
Predicted h-index
57
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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Lipids from ocular meibum and tears may serve as biomarkers for depression and post‐traumatic stress disorder (journal article)
Gary, Ashlyn A. | Prislovsky, Amanda | Tovar, Arianna | Locatelli, Elyana | Felix, Elizabeth R. | Stephenson, Daniel | Chalfant, Charles E. | Lai, James | Kim, Colin | Mandal, Nawajes | Galor, Anat
Clinical & Experimental Ophthalmology, volume 52, issue 5, pages 516-527 (2024).
10.1111/ceo.14343
Cited by (1) | Cite | Source
Sphingolipid changes in mouse brain and plasma after mild traumatic brain injury at the acute phases (journal article)
Mondal, Koushik | Del Mar, Nobel A. | Gary, Ashlyn A. | Grambergs, Richard C. | Yousuf, Mohd | Tahia, Faiza | Stephenson, Benjamin | Stephenson, Daniel J. | Chalfant, Charles E. | Reiner, Anton | Mandal, Nawajes
Lipids in Health and Disease, volume 23, issue 1 (2024).
10.1186/s12944-024-02186-x
Cite | Source
124-OR: Intervention of Select Lipid Signaling Reduces Type 1 Diabetes Incidence (journal article)
White, Tayleur | Almutairi, Abdulaziz | Tusing, Ying | Hammock, Bruce | Mcreynolds, Cindy | Stephenson, Daniel | Chalfant, Charles E. | Ramanadham, Sasanka
Diabetes, volume 73, issue Supplement_1 (2024).
10.2337/db24-124-OR
Cite | Source
Sphingolipid biosynthetic inhibitor L-Cycloserine prevents oxidative-stress-mediated death in an in vitro model of photoreceptor-derived 661W cells (journal article)
Tahia, Faiza | Basu, Sandip K. | Prislovsky, Amanda | Mondal, Koushik | Ma, Dejian | Kochat, Harry | Brown, Kennard | Stephenson, Daniel J. | Chalfant, Charles E. | Mandal, Nawajes
Experimental Eye Research, volume 242 (2024).
10.1016/j.exer.2024.109852
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Ceramide-1-phosphate is a regulator of Golgi structure and is co-opted by the obligate intracellular bacterial pathogen Anaplasma phagocytophilum (journal article)
Read, Curtis B. | Ali, Anika N. | Stephenson, Daniel J. | Macknight, H. Patrick | Maus, Kenneth D. | Cockburn, Chelsea L. | Kim, Minjung | Xie, Xiujie | Carlyon, Jason A. | Chalfant, Charles E.
mBio, volume 15, issue 4 (2024).
10.1128/mbio.00299-24
Cite | Source
Role of Polyunsaturated Fatty Acids (PUFAs) and Eicosanoids on Dry Eye Symptoms and Signs (journal article)
Mangwani-Mordani, Simran | Prislovsky, Amanda | Stephenson, Daniel | Chalfant, Charles E. | Galor, Anat | Mandal, Nawajes
Biomolecules, volume 14, issue 3, pages 376- (2024).
10.3390/biom14030376
Cited by (1) | Cite | Source
Mouse Model of Nitrogen Mustard Ocular Surface Injury Characterization and Sphingolipid Signaling (journal article)
Basu, Sandip K. | Prislovsky, Amanda | Lenchik, Nataliya | Stephenson, Daniel J. | Agarwal, Rajesh | Chalfant, Charles E. | Mandal, Nawajes
International Journal of Molecular Sciences, volume 25, issue 2, pages 742- (2024).
10.3390/ijms25020742
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Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia (journal article)
Ung, Johnson | Tan, Su-Fern | Fox, Todd E. | Shaw, Jeremy J. P. | Taori, Maansi | Horton, Bethany J. | Golla, Upendarrao | Sharma, Arati | Szulc, Zdzislaw M. | Wang, Hong-Gang | ... | Feith, David J.
Cancers, volume 15, issue 24, pages 5866- (2023).
10.3390/cancers15245866
Cite | Source
Ceramide synthesis regulates biogenesis and packaging of exosomal MALAT1 from adipose derived stem cells, increases dermal fibroblast migration and mitochondrial function (journal article)
Kong, Xaioyuan | Patel, Niketa A. | Chalfant, Charles E. | Cooper, Denise R.
Cell Communication and Signaling, volume 21, issue 1 (2023).
10.1186/s12964-022-00900-9
Cited by (4) | Cite | Source
Skewing cPLA2 α activity toward oxoeicosanoid production promotes neutrophil N2 polarization, wound healing, and the response to sepsis (journal article)
Maus, Kenneth D. | Stephenson, Daniel J. | Macknight, H. Patrick | Vu, Ngoc T. | Hoeferlin, L. Alexis | Kim, Minjung | Diegelmann, Robert F. | Xie, Xiujie | Chalfant, Charles E.
Science Signaling, volume 16, issue 793 (2023).
10.1126/scisignal.add6527
Cited by (5) | Cite | Source
32-OR: Reduction of Macrophage-iPLA2ß–Derived Proinflammatory Lipids Inhibit Type 1 Diabetes Development (journal article)
Almutairi, Abdulaziz | GAI, Ying | Nadler, Jerry | Chalfant, Charles E. | Ramanadham, Sasanka
Diabetes, volume 72, issue Supplement_1 (2023).
10.2337/db23-32-OR
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1488-P: Reduced iPLA2b Expression in T-Lymphocytes Decreases Proinflammatory Eicosanoid Production and Cytokine Secretion Delaying Type 1 Diabetes Development in NOD Mice (journal article)
White, Tayleur | Ramanadham, Sasanka | Dilorenzo, Teresa P. | Chalfant, Charles E.
Diabetes, volume 72, issue Supplement_1 (2023).
10.2337/db23-1488-P
Cite | Source
Bioactive lipid mediators in plasma are predictors of preeclampsia irrespective of aspirin therapy (journal article)
Stephenson, Daniel J. | MacKnight, H. Patrick | Hoeferlin, L. Alexis | Washington, Sonya L. | Sawyers, Chelsea | Archer, Kellie J. | Strauss, Jerome F. | Walsh, Scott W. | Chalfant, Charles E.
Journal of Lipid Research, volume 64, issue 6, pages 100377- (2023).
10.1016/j.jlr.2023.100377
Cited by (6) | Cite | Source
Simultaneous Inhibition of Ceramide Hydrolysis and Glycosylation Synergizes to Corrupt Mitochondrial Respiration and Signal Caspase Driven Cell Death in Drug-Resistant Acute Myeloid Leukemia (journal article)
Fisher-Wellman, Kelsey H. | Kassai, Miki | Hagen, James T. | Neufer, P. Darrell | Kester, Mark | Loughran, Thomas P. | Chalfant, Charles E. | Feith, David J. | Tan, Su-Fern | Fox, Todd E. | ... | Cabot, Myles C.
Cancers, volume 15, issue 6, pages 1883- (2023).
10.3390/cancers15061883
Cited by (2) | Cite | Source
Ceramide Kinase Inhibition Drives Ferroptosis and Sensitivity to Cisplatin in Mutant KRAS Lung Cancer by Dysregulating VDAC-Mediated Mitochondria Function (journal article)
Vu, Ngoc T. | Kim, Minjung | Stephenson, Daniel J. | MacKnight, H. Patrick | Chalfant, Charles E.
Molecular Cancer Research, volume 20, issue 9, pages 1429-1442 (2022).
10.1158/1541-7786.MCR-22-0085
Cited by (26) | Cite | Source
Caspase 9b Drives Cellular Transformation, Lung Inflammation, and Lung Tumorigenesis (journal article)
Kim, Minjung | Vu, Ngoc T. | Wang, Xue | Bulut, Gamze B. | Wang, Min-Hsuan | Uram-Tuculescu, Cora | Pillappa, Raghavendra | Kim, Sungjune | Chalfant, Charles E.
Molecular Cancer Research, volume 20, issue 8, pages 1284-1294 (2022).
10.1158/1541-7786.MCR-21-0905
Cited by (5) | Cite | Source
Hydroxychloroquine Causes Early Inner Retinal Toxicity and Affects Autophagosome–Lysosomal Pathway and Sphingolipid Metabolism in the Retina (journal article)
Mondal, Koushik | Porter, Hunter | Cole, Jerome | Pandya, Hemang K. | Basu, Sandip K. | Khanam, Sufiya | Chiu, Chi-Yang | Shah, Vinay | Stephenson, Daniel J. | Chalfant, Charles E. | Mandal, Nawajes
Molecular Neurobiology, volume 59, issue 6, pages 3873-3887 (2022).
10.1007/s12035-022-02825-3
Cited by (11) | Cite | Source
74-OR: Adoptively Transferred T Lymphocytes with Reduced iPLA2b Expression Delays Type 1 Diabetes Development in NOD Mice (journal article)
White, Tayleur | Chalfant, Charles | Dilorenzo, Teresa P. | Ramanadham, Sasanka | Stephenson, Daniel
Diabetes, volume 71, issue Supplement_1 (2022).
10.2337/db22-74-OR
Cite | Source
76-OR: Macrophage-Derived Proinflammatory Lipids Play a Role in the Development of Type 1 Diabetes (journal article)
Almutairi, Abdulaziz | White, Tayleur | Stephenson, Daniel | GAI, Ying | Ubil, Eric | Chalfant, Charles | Ramanadham, Sasanka
Diabetes, volume 71, issue Supplement_1 (2022).
10.2337/db22-76-OR
Cite | Source
Ceramide kinase regulates acute wound healing by suppressing 5-oxo-ETE biosynthesis and signaling via its receptor OXER1 (journal article)
Maus, Kenneth D. | Stephenson, Daniel J. | Ali, Anika N. | MacKnight, Henry Patrick | Huang, Huey-Jing | Serrats, Jordi | Kim, Minjung | Diegelmann, Robert F. | Chalfant, Charles E.
Journal of Lipid Research, volume 63, issue 4, pages 100187- (2022).
10.1016/j.jlr.2022.100187
Cited by (13) | Cite | Source