Luet-Lok Wong

ScholarGPS® ID: 68960514157079

Affiliation

University of Oxford, Oxford, United Kingdom

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Metrics Summary

Publication Count

144

Predicted Citations

8,650

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Selective P450BM3 Hydroxylation of Cyclobutylamine and Bicyclo[1.1.1]pentylamine Derivatives: Underpinning Synthetic Chemistry for Drug Discovery (journal article) Harwood, Lucy A. \| Xiong, Ziyue \| Christensen, Kirsten E. \| Wang, Ruiyao \| Wong, Luet L. \| Robertson, Jeremy Journal of the American Chemical Society, volume 145, issue 50, pages 27767-27773 (2023). 10.1021/jacs.3c10542 Cited by (8) \| Cite \| Source
Two Total Syntheses of Trigoxyphins K and L (journal article) Li, Shuyang \| O’Hanlon, Jack A. \| Mattimoe, Andrew \| Pickford, Helena D. \| Harwood, Lucy A. \| Wong, Luet L. \| Robertson, Jeremy Organic Letters, volume 25, issue 41, pages 7507-7511 (2023). 10.1021/acs.orglett.3c02796 Cite \| Source
Enantioselective oxidation of unactivated C–H bonds in cyclic amines by iterative docking-guided mutagenesis of P450BM3 (CYP102A1) (journal article) Zhang, Yuan \| Xiong, Ziyue \| Li, Yushu \| Wilson, Mary \| Christensen, Kirsten E. \| Jaques, Ellie \| Hernández-Lladó, Pol \| Robertson, Jeremy \| Wong, Luet L. Nature Synthesis, volume 1, issue 12, pages 936-945 (2022). 10.1038/s44160-022-00166-6 Cited by (9) \| Cite \| Source
Enzymatic Kinetic Resolution by Addition of Oxygen (journal article) Harwood, Lucy A. \| Wong, Luet L. \| Robertson, Jeremy Angewandte Chemie International Edition, volume 60, issue 9, pages 4434-4447 (2021). 10.1002/anie.202011468 Cited by (15) \| Cite \| Source
Enzymatic Kinetic Resolution by Addition of Oxygen (journal article) Harwood, Lucy A. \| Wong, Luet L. \| Robertson, Jeremy Angewandte Chemie, volume 133, issue 9, pages 4482-4495 (2021). 10.1002/ange.202011468 Cite \| Source
Dihydrogen‐Driven NADPH Recycling in Imine Reduction and P450‐Catalyzed Oxidations Mediated by an Engineered O2 ‐Tolerant Hydrogenase (journal article) Preissler, Janina \| Reeve, Holly A. \| Zhu, Tianze \| Nicholson, Jake \| Urata, Kouji \| Lauterbach, Lars \| Wong, Luet L. \| Vincent, Kylie A. \| Lenz, Oliver ChemCatChem, volume 12, issue 19, pages 4853-4861 (2020). 10.1002/cctc.202000763 Cited by (14) \| Cite \| Source
Cryo-EM structure of trimeric Mycobacterium smegmatis succinate dehydrogenase with a membrane-anchor SdhF (journal article) Gong, Hongri \| Gao, Yan \| Zhou, Xiaoting \| Xiao, Yu \| Wang, Weiwei \| Tang, Yanting \| Zhou, Shan \| Zhang, Yuying \| Ji, Wenxin \| Yu, Lu \| ... \| Rao, Zihe Nature Communications, volume 11, issue 1 (2020). 10.1038/s41467-020-18011-9 Cited by (20) \| Cite \| Source
Oxidative Diversification of Steroids by Nature-Inspired Scanning Glycine Mutagenesis of P450BM3 (CYP102A1) (journal article) Chen, Wenyu \| Fisher, Matthew J. \| Leung, Aaron \| Cao, Yang \| Wong, Luet L. ACS Catalysis, volume 10, issue 15, pages 8334-8343 (2020). 10.1021/acscatal.0c02077 Cited by (41) \| Cite \| Source
Biophysical Techniques for Distinguishing Ligand Binding Modes in Cytochrome P450 Monooxygenases (journal article) Podgorski, Matthew N. \| Harbort, Joshua S. \| Coleman, Tom \| Stok, Jeanette E. \| Yorke, Jake A. \| Wong, Luet-Lok \| Bruning, John B. \| Bernhardt, Paul V. \| De Voss, James J. \| Harmer, Jeffrey R. \| Bell, Stephen G. Biochemistry, volume 59, issue 9, pages 1038-1050 (2020). 10.1021/acs.biochem.0c00027 Cited by (23) \| Cite \| Source
Multi‐Functional Oxidase Activity of CYP102A1 (P450BM3) in the Oxidation of Quinolines and Tetrahydroquinolines (journal article) Li, Yushu \| Wong, Luet L. Angewandte Chemie, volume 131, issue 28, pages 9651-9655 (2019). 10.1002/ange.201904157 Cited by (14) \| Cite \| Source
Multi‐Functional Oxidase Activity of CYP102A1 (P450BM3) in the Oxidation of Quinolines and Tetrahydroquinolines (journal article) Li, Yushu \| Wong, Luet L. Angewandte Chemie International Edition, volume 58, issue 28, pages 9551-9555 (2019). 10.1002/anie.201904157 Cited by (38) \| Cite \| Source
Hydroxylation of Eleuthoside Synthetic Intermediates by P450BM3 (CYP102A1) (journal article) Syntrivanis, Leonidas‐Dimitrios \| Wong, Luet Lok \| Robertson, Jeremy European Journal of Organic Chemistry, volume 2018, issue 45, pages 6369-6378 (2018). 10.1002/ejoc.201801206 Cited by (12) \| Cite \| Source
An electron transfer path connects subunits of a mycobacterial respiratory supercomplex (journal article) Gong, Hongri \| Li, Jun \| Xu, Ao \| Tang, Yanting \| Ji, Wenxin \| Gao, Ruogu \| Wang, Shuhui \| Yu, Lu \| Tian, Changlin \| Li, Jingwen \| ... \| Rao, Zihe Science, volume 362, issue 6418 (2018). 10.1126/science.aat8923 Cited by (109) \| Cite \| Source
An electron transfer path connects subunits of a mycobacterial respiratory supercomplex. (journal article) Gong, H. \| Li, Jiayuan \| Li, Jiayuan \| Xu, A. \| Xu, A. \| Tang, Y. \| Ji, Wei \| Gao, Rui \| Wang, Sumin \| Wang, Sumin \| ... \| Rao, Z. Science, volume 362, issue 6418 (2018). 10.2210/pdb6adq/pdb Cite \| Source
A Structural Model of a P450-Ferredoxin Complex from Orientation-Selective Double Electron–Electron Resonance Spectroscopy (journal article) Bowen, Alice M. \| Johnson, Eachan O. D. \| Mercuri, Francesco \| Hoskins, Nicola J. \| Qiao, Ruihong \| McCullagh, James S. O. \| Lovett, Janet E. \| Bell, Stephen G. \| Zhou, Weihong \| Timmel, Christiane R. \| ... \| Harmer, Jeffrey R. Journal of the American Chemical Society, volume 140, issue 7, pages 2514-2527 (2018). 10.1021/jacs.7b11056 Cited by (21) \| Cite \| Source
Hydroxylation of anilides by engineered cytochrome P450BM3 (journal article) O'Hanlon, Jack A. \| Ren, Xinkun \| Morris, Melloney \| Wong, Luet Lok \| Robertson, Jeremy Org. Biomol. Chem., volume 15, issue 41, pages 8780-8787 (2017). 10.1039/C7OB02236K Cited by (19) \| Cite \| Source
Synthesis of Imidazolidin-4-ones via a Cytochrome P450-Catalyzed Intramolecular C–H Amination (journal article) Ren, Xinkun \| O’Hanlon, Jack A. \| Morris, Melloney \| Robertson, Jeremy \| Wong, Luet Lok ACS Catalysis, volume 6, issue 10, pages 6833-6837 (2016). 10.1021/acscatal.6b02189 Cited by (39) \| Cite \| Source
Improved oxidation of aromatic and aliphatic hydrocarbons using rate enhancing variants of P450Bm3 in combination with decoy molecules (journal article) Munday, Samuel D. \| Shoji, Osami \| Watanabe, Yoshihito \| Wong, Luet-Lok \| Bell, Stephen G. Chemical Communications, volume 52, issue 5, pages 1036-1039 (2016). 10.1039/C5CC09247G Cited by (35) \| Cite \| Source
Partial fusion of a cytochrome P450 system by carboxy-terminal attachment of putidaredoxin reductase to P450cam (CYP101A1) (journal article) Johnson, Eachan O. D. \| Wong, Luet-Lok Catalysis Science & Technology, volume 6, issue 20, pages 7549-7560 (2016). 10.1039/C6CY01042C Cited by (7) \| Cite \| Source \| Open Access
Drug Oxidation by Cytochrome P450BM3 : Metabolite Synthesis and Discovering New P450 Reaction Types (journal article) Ren, Xinkun \| Yorke, Jake A. \| Taylor, Emily \| Zhang, Ting \| Zhou, Weihong \| Wong, Luet Lok Chemistry – A European Journal, volume 21, issue 42, pages 15039-15047 (2015). 10.1002/chem.201502020 Cited by (73) \| Cite \| Source