Romel Somwar

ScholarGPS® ID: 66677003190852

Affiliation

Memorial Sloan Kettering Cancer Center, New York, United States

Affiliation History

Field

Medicine

Discipline

Pathology

Top Specialties

Metrics Summary

Publication Count

111

Predicted Citations

14,229

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Overcoming Clinical Resistance to EZH2 Inhibition Using Rational Epigenetic Combination Therapy (journal article) Kazansky, Yaniv \| Cameron, Daniel \| Mueller, Helen S. \| Demarest, Phillip \| Zaffaroni, Nadia \| Arrighetti, Noemi \| Zuco, Valentina \| Kuwahara, Yasumichi \| Somwar, Romel \| Ladanyi, Marc \| ... \| Kentsis, Alex Cancer Discovery, volume 14, issue 6, pages 965-981 (2024). 10.1158/2159-8290.CD-23-0110 Cited by (3) \| Cite \| Source
Prevalence and Therapeutic Targeting of High-Level ERBB2 Amplification in NSCLC (journal article) Odintsov, Igor \| Makarem, Maisam \| Nishino, Mizuki \| Bachert, Sara Emily \| Zhang, Tom \| LoPiccolo, Jaclyn \| Paweletz, Cloud P. \| Gokhale, Prafulla C. \| Ivanova, Elena \| Saldanha, Aisha \| ... \| Sholl, Lynette M. Journal of Thoracic Oncology, volume 19, issue 5, pages 732-748 (2024). 10.1016/j.jtho.2023.12.019 Cited by (2) \| Cite \| Source
HER4 and EGFR Activate Cell Signaling in NRG1 Fusion-Driven Cancers: Implications for HER2-HER3-specific Versus Pan-HER Targeting Strategies (journal article) Udagawa, Hibiki \| Nilsson, Monique B. \| Robichaux, Jacqulyne P. \| He, Junqin \| Poteete, Alissa \| Jiang, Hong \| Heeke, Simon \| Elamin, Yasir Y. \| Shibata, Yuji \| Matsumoto, Shingo \| ... \| Heymach, John V. Journal of Thoracic Oncology, volume 19, issue 1, pages 106-118 (2024). 10.1016/j.jtho.2023.08.034 Cited by (1) \| Cite \| Source
P2.09-14 Clinical Characteristics and Outcomes of Patients with EGFR-mutant Lung Cancer with Acquired BRAF Alterations (journal article) Sui, J. \| Yang, S.R. \| Bowman, A.S. \| Vankayala, P. \| Falcon, C. \| Somwar, R. \| Drilon, A.E. \| Riely, G.J. \| Kris, M.G. \| Ladanyi, M. \| ... \| Offin, M. Journal of Thoracic Oncology, volume 18, issue 11, pages S337- (2023). 10.1016/j.jtho.2023.09.588 Cite \| Source
2295P Pan-cancer prevalence of MET fusions and clinical response to MET- targeted therapy (journal article) Vojnic, M. \| Odintsov, I. \| Liu, Z. \| Lu, D. \| Harshan, M. \| Ameri, A. \| Machnicki, S. \| Xiao, X. \| Lockwood, W. \| Ladanyi, M. \| Somwar, R. Annals of Oncology, volume 34 (2023). 10.1016/j.annonc.2023.09.1322 Cite \| Source
Tumor-agnostic genomic and clinical analysis of solid tumors with BRAF fusions. (journal article) Chen, Monica F \| Yang, Soo-Ryum \| Tao, Jessica \| Desilets, Antoine \| Rosen, Ezra \| Gong, Yixuan \| Mullaney, Kerry A. \| Kris, Mark G. \| Arcila, Maria E. \| Donoghue, Mark \| ... \| Murciano-Goroff, Yonina R. Journal of Clinical Oncology, volume 41, issue 16_suppl, pages 3146-3146 (2023). 10.1200/JCO.2023.41.16_suppl.3146 Cite \| Source
47MO Activating EZH2 mutations define a new subset of aggressive Ewing sarcomas (journal article) Sobczuk, P. \| Zhang, T. \| Dermawan, J. \| Koche, R.P. \| Hamard, P-J. \| Jagodzinska-Mucha, P. \| Rutkowski, P. \| Somwar, R. \| Ladanyi, M. ESMO Open, volume 8, issue 1, pages 101084- (2023). 10.1016/j.esmoop.2023.101084 Cite \| Source
Desmoplastic small round cell tumor cancer stem cell-like cells resist chemotherapy but remain dependent on the EWSR1-WT1 oncoprotein (journal article) Magrath, Justin W. \| Kang, Hong-Jun \| Hartono, Alifiani \| Espinosa-Cotton, Madelyn \| Somwar, Romel \| Ladanyi, Marc \| Cheung, Nai-Kong V. \| Lee, Sean B. Frontiers in Cell and Developmental Biology, volume 10 (2022). 10.3389/fcell.2022.1048709 Cited by (8) \| Cite \| Source
MEK inhibitor resistance in lung adenocarcinoma is associated with addiction to sustained ERK suppression (journal article) Farnsworth, Dylan A. \| Inoue, Yusuke \| Johnson, Fraser D. \| de Rappard-Yuswack, Georgia \| Lu, Daniel \| Shi, Rocky \| Ma, Lok In Josephine \| Mattar, Marissa S. \| Somwar, Romel \| Ladanyi, Marc \| ... \| Lockwood, William W. npj Precision Oncology, volume 6, issue 1 (2022). 10.1038/s41698-022-00328-x Cited by (9) \| Cite \| Source
Vepafestinib is effective in preclinical models of sarcomas with RET fusion including a brain metastasis model (journal article) Odintsov, I. \| Liu, A. \| Khodos, I. \| Chang, Q. \| Giuliano, C. \| Mattar, M. \| Vojnic, M. \| Bonifacio, A. \| De Stanchina, E. \| Lovati, E. \| ... \| Somwar, R. European Journal of Cancer, volume 174 (2022). 10.1016/S0959-8049(22)00874-7 Cited by (1) \| Cite \| Source
MA13.05 TA0953/HM06, a Novel RET-specific Inhibitor Effective in Extracranial and CNS Disease Models of NSCLC with RETfusions (journal article) Odintsov, I. \| Lui, A.J.W. \| Delasos, L. \| Khodos, I. \| Chang, Q. \| Mattar, M.S. \| Vojnic, M. \| Lu, Y.C. \| Kunte, S. \| Bonifacio, A. \| ... \| Somwar, R. Journal of Thoracic Oncology, volume 17, issue 9, pages S90-S91 (2022). 10.1016/j.jtho.2022.07.151 Cited by (1) \| Cite \| Source
Comparison of TAS0953/HM06 and selpercatinib in RET fusion-driven preclinical disease models of intracranial metastases. (journal article) Odintsov, Igor \| Lui, Allan J.W. \| Ishizawa, Kota \| Miyazaki, Isao \| Khodos, Inna \| Wakayama, Kentaro \| Vojnic, Morana \| Hagen, Connor J. \| Chang, Qing \| Bonifacio, Annalisa \| ... \| Somwar, Romel Journal of Clinical Oncology, volume 40, issue 16_suppl, pages 2024-2024 (2022). 10.1200/JCO.2022.40.16_suppl.2024 Cited by (8) \| Cite \| Source
Targeting farnesylation as a novel therapeutic approach in HRAS-mutant rhabdomyosarcoma (journal article) Odeniyide, Patience \| Yohe, Marielle E. \| Pollard, Kai \| Vaseva, Angelina V. \| Calizo, Ana \| Zhang, Lindy \| Rodriguez, Fausto J. \| Gross, John M. \| Allen, Amy N. \| Wan, Xiaolin \| ... \| Pratilas, Christine A. Oncogene, volume 41, issue 21, pages 2973-2983 (2022). 10.1038/s41388-022-02305-x Cited by (12) \| Cite \| Source
MYC Promotes Tyrosine Kinase Inhibitor Resistance in ROS1 -Fusion-Positive Lung Cancer (journal article) Iyer, Sudarshan R. \| Odintsov, Igor \| Schoenfeld, Adam J. \| Siau, Evan \| Mattar, Marissa S. \| de Stanchina, Elisa \| Khodos, Inna \| Drilon, Alexander \| Riely, Gregory J. \| Ladanyi, Marc \| ... \| Davare, Monika A. Molecular Cancer Research, volume 20, issue 5, pages 722-734 (2022). 10.1158/1541-7786.MCR-22-0025 Cited by (6) \| Cite \| Source
Salt-Inducible Kinase 1 is a potential therapeutic target in Desmoplastic Small Round Cell Tumor (journal article) Hartono, Alifiani Bonita \| Kang, Hong-Jun \| Shi, Lawrence \| Phipps, Whitney \| Ungerleider, Nathan \| Giardina, Alexandra \| Chen, WeiPing \| Spraggon, Lee \| Somwar, Romel \| Moroz, Krzysztof \| ... \| Lee, Sean Bong Oncogenesis, volume 11, issue 1 (2022). 10.1038/s41389-022-00395-6 Cited by (10) \| Cite \| Source
CIC-Mediated Modulation of MAPK Signaling Opposes Receptor Tyrosine Kinase Inhibitor Response in Kinase-Addicted Sarcoma (journal article) Odintsov, Igor \| Ortiz, Michael V. \| Khodos, Inna \| Mattar, Marissa S. \| Lui, Allan J.W. \| Kohsaka, Shinji \| de Stanchina, Elisa \| Bender, Julia L. Glade \| Ladanyi, Marc \| Somwar, Romel Cancer Research, volume 82, issue 6, pages 1110-1127 (2022). 10.1158/0008-5472.CAN-21-1397 Cited by (3) \| Cite \| Source
MET Exon 14 Splice-Site Mutations Preferentially Activate KRAS Signaling to Drive Tumourigenesis (journal article) Lu, Daniel \| Nagelberg, Amy \| Chow, Justine LM \| Chen, Yankuan T \| Michalchuk, Quentin \| Somwar, Romel \| Lockwood, William W. Cancers, volume 14, issue 6, pages 1378- (2022). 10.3390/cancers14061378 Cited by (7) \| Cite \| Source
Resistance Profile and Structural Modeling of Next-Generation ROS1 Tyrosine Kinase Inhibitors (journal article) Keddy, Clare \| Shinde, Pushkar \| Jones, Kristen \| Kaech, Stefanie \| Somwar, Romel \| Shinde, Ujwal \| Davare, Monika A. Molecular Cancer Therapeutics, volume 21, issue 2, pages 336-346 (2022). 10.1158/1535-7163.MCT-21-0395 Cited by (20) \| Cite \| Source
Novel patient-derived models of desmoplastic small round cell tumor confirm a targetable dependency on ERBB signaling (journal article) Smith, Roger S. \| Odintsov, Igor \| Liu, Zebing \| Lui, Allan Jo-Weng \| Hayashi, Takuo \| Vojnic, Morana \| Suehara, Yoshiyuki \| Delasos, Lukas \| Mattar, Marissa S. \| Hmeljak, Julija \| ... \| Somwar, Romel Disease Models & Mechanisms, volume 15, issue 1 (2022). 10.1242/dmm.047621 Cited by (13) \| Cite \| Source
Functional impact and targetability of PI3KCA , GNAS , and PTEN mutations in a spindle cell rhabdomyosarcoma with MYOD1 L122R mutation (journal article) Choo, Florence \| Odintsov, Igor \| Nusser, Kevin \| Nicholson, Katelyn S. \| Davis, Lara \| Corless, Christopher L. \| Stork, Linda \| Somwar, Romel \| Ladanyi, Marc \| Davis, Jessica L. \| Davare, Monika A. Molecular Case Studies, volume 8, issue 1, pages a006140- (2022). 10.1101/mcs.a006140 Cited by (10) \| Cite \| Source