Valentina Zuco

ScholarGPS® ID: 66450196518562

Affiliation

Istituto Nazionale Per Lo Studio E La Cura Dei Tumori

Affiliation History

Field

Pharmacy and Pharmaceutical Sciences

Discipline

Pharmacology and Toxicology

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

3,394

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Overcoming Clinical Resistance to EZH2 Inhibition Using Rational Epigenetic Combination Therapy (journal article) Kazansky, Yaniv \| Cameron, Daniel \| Mueller, Helen S. \| Demarest, Phillip \| Zaffaroni, Nadia \| Arrighetti, Noemi \| Zuco, Valentina \| Kuwahara, Yasumichi \| Somwar, Romel \| Ladanyi, Marc \| ... \| Kentsis, Alex Cancer Discovery, volume 14, issue 6, pages 965-981 (2024). 10.1158/2159-8290.CD-23-0110 Cited by (3) \| Cite \| Source
Effectiveness of irinotecan plus trabectedin on a desmoplastic small round cell tumor patient-derived xenograft (journal article) Zuco, Valentina \| Pasquali, Sandro \| Tortoreto, Monica \| Percio, Stefano \| Doldi, Valentina \| Barisella, Marta \| Collini, Paola \| Dagrada, Gian Paolo \| Brich, Silvia \| Gasparini, Patrizia \| ... \| Zaffaroni, Nadia Disease Models & Mechanisms, volume 16, issue 6 (2023). 10.1242/dmm.049649 Cited by (5) \| Cite \| Source
Tazemetostat and doxorubicin in patient-derived preclinical models of epithelioid sarcoma (ES) (journal article) Pasquali, S. \| Arrighetti, N. \| Zuco, V. \| Tortoreto, M. \| Soffientini, C. \| Sigalotti, L. \| Maestro, R. \| Percio, S. \| Barisella, M. \| Collini, P. \| ... \| Zaffaroni, N. European Journal of Cancer, volume 174 (2022). 10.1016/S0959-8049(22)00984-4 Cite \| Source
miR-550a-3p is a prognostic biomarker and exerts tumor-suppressive functions by targeting HSP90AA1 in diffuse malignant peritoneal mesothelioma (journal article) El Bezawy, Rihan \| Percio, Stefano \| Ciniselli, Chiara Maura \| De Cesare, Michelandrea \| Colella, Gennaro \| Dugo, Matteo \| Veneroni, Silvia \| Doldi, Valentina \| Martini, Silvia \| Baratti, Dario \| ... \| Zuco, Valentina Cancer Gene Therapy, volume 29, issue 10, pages 1394-1404 (2022). 10.1038/s41417-022-00460-7 Cited by (3) \| Cite \| Source
Epitheliod hemagioendothelioma (EHE) patient-derived model (PDX): Drug activity assessment and validation of novel biomarkers. (journal article) Stacchiotti, Silvia \| Zuco, Valentina \| Frezza, Anna Maria \| Pasquali, Sandro \| Tortoreto, Monica \| Martini, Silvia \| Barisella, Marta \| Dagrada, Gianpaolo \| Huang, Paul \| Jones, Robin Lewis \| ... \| Zaffaroni, Nadia Journal of Clinical Oncology, volume 40, issue 16_suppl, pages 11566-11566 (2022). 10.1200/JCO.2022.40.16_suppl.11566 Cite \| Source
Telomere as a Therapeutic Target in Dedifferentiated Liposarcoma (journal article) Alessandrini, Irene \| Percio, Stefano \| Naghshineh, Eisa \| Zuco, Valentina \| Stacchiotti, Silvia \| Gronchi, Alessandro \| Pasquali, Sandro \| Zaffaroni, Nadia \| Folini, Marco Cancers, volume 14, issue 11, pages 2624- (2022). 10.3390/cancers14112624 Cited by (2) \| Cite \| Source
Selinexor versus doxorubicin in dedifferentiated liposarcoma PDXs: evidence of greater activity and apoptotic response dependent on p53 nuclear accumulation and survivin down‐regulation (journal article) Zuco, Valentina \| Pasquali, Sandro \| Tortoreto, Monica \| Brich, Silvia \| Percio, Stefano \| Dagrada, Gian Paolo \| Colombo, Chiara \| Sanfilippo, Roberta \| Lauricella, Calogero \| Gounder, Mrinal \| ... \| Zaffaroni, Nadia Journal of Experimental & Clinical Cancer Research, volume 40, issue 1 (2021). 10.1186/s13046-021-01886-x Cited by (14) \| Cite \| Source
δ‐Tocotrienol sensitizes and re‐sensitizes ovarian cancer cells to cisplatin via induction of G1 phase cell cycle arrest and ROS/MAPK‐mediated apoptosis (journal article) Fontana, Fabrizio \| Marzagalli, Monica \| Raimondi, Michela \| Zuco, Valentina \| Zaffaroni, Nadia \| Limonta, Patrizia Cell Proliferation, volume 54, issue 11 (2021). 10.1111/cpr.13111 Cited by (27) \| Cite \| Source
miR-34a-Mediated Survivin Inhibition Improves the Antitumor Activity of Selinexor in Triple-Negative Breast Cancer (journal article) Martini, Silvia \| Zuco, Valentina \| Tortoreto, Monica \| Percio, Stefano \| Campi, Elisa \| El Bezawy, Rihan \| Doldi, Valentina \| Landesman, Yosef \| Pennati, Marzia \| Zaffaroni, Nadia Pharmaceuticals, volume 14, issue 6, pages 523- (2021). 10.3390/ph14060523 Cited by (9) \| Cite \| Source
Trabectedin (T) in desmoplastic small round cell tumor (DSRCT): Report of its effect in 3 relapsed patients (pts) and the comparison of different regimens in a patient-derived xenograft (PDX) model. (journal article) Stacchiotti, Silvia \| Frezza, Anna Maria \| Gronchi, Alessandro \| Pasquali, Sandro \| Radaelli, Stefano \| Fiore, Marco \| Morosi, Carlo \| Collini, Paola \| Dagrada, Gianpaolo \| Casali, Paolo Giovanni \| ... \| Zaffaroni, Nadia Journal of Clinical Oncology, volume 39, issue 15_suppl, pages e23553-e23553 (2021). 10.1200/JCO.2021.39.15_suppl.e23553 Cite \| Source
SPOP Deregulation Improves the Radiation Response of Prostate Cancer Models by Impairing DNA Damage Repair (journal article) El Bezawy, Rihan \| Tripari, Martina \| Percio, Stefano \| Cicchetti, Alessandro \| Tortoreto, Monica \| Stucchi, Claudio \| Tinelli, Stella \| Zuco, Valentina \| Doldi, Valentina \| Gandellini, Paolo \| ... \| Zaffaroni, Nadia Cancers, volume 12, issue 6, pages 1462- (2020). 10.3390/cancers12061462 Cited by (8) \| Cite \| Source
miR-1272 Exerts Tumor-Suppressive Functions in Prostate Cancer via HIP1 Suppression (journal article) Rotundo, Federica \| Cominetti, Denis \| El Bezawy, Rihan \| Percio, Stefano \| Doldi, Valentina \| Tortoreto, Monica \| Zuco, Valentina \| Valdagni, Riccardo \| Zaffaroni, Nadia \| Gandellini, Paolo Cells, volume 9, issue 2, pages 435- (2020). 10.3390/cells9020435 Cited by (10) \| Cite \| Source
Exosome-like Nanovectors for Drug Delivery in Cancer (journal article) Arrighetti, Noemi \| Corbo, Claudia \| Evangelopoulos, Michael \| Pastò, Anna \| Zuco, Valentina \| Tasciotti, Ennio Current Medicinal Chemistry, volume 26, issue 33, pages 6132-6148 (2019). 10.2174/0929867325666180831150259 Cited by (80) \| Cite \| Source
miR-205 enhances radiation sensitivity of prostate cancer cells by impairing DNA damage repair through PKCε and ZEB1 inhibition (journal article) El Bezawy, Rihan \| Tinelli, Stella \| Tortoreto, Monica \| Doldi, Valentina \| Zuco, Valentina \| Folini, Marco \| Stucchi, Claudio \| Rancati, Tiziana \| Valdagni, Riccardo \| Gandellini, Paolo \| Zaffaroni, Nadia Journal of Experimental & Clinical Cancer Research, volume 38, issue 1 (2019). 10.1186/s13046-019-1060-z Cited by (55) \| Cite \| Source
Comparative Assessment of Antitumor Effects and Autophagy Induction as a Resistance Mechanism by Cytotoxics and EZH2 Inhibition in INI1-Negative Epithelioid Sarcoma Patient-Derived Xenograft (journal article) Stacchiotti, Silvia \| Zuco, Valentina \| Tortoreto, Monica \| Cominetti, Denis \| Frezza, Anna Maria \| Percio, Stefano \| Indio, Valentina \| Barisella, Marta \| Monti, Valentina \| Brich, Silvia \| ... \| Zaffaroni, Nadia Cancers, volume 11, issue 7, pages 1015- (2019). 10.3390/cancers11071015 Cited by (21) \| Cite \| Source
Doxorubicin (D), gemcitabine (G), ifosfamide (I) and the EZH2 inhibitor EPZ-011989 in epithelioid sarcoma (ES): A comparison of different regimens in a patient-derived xenograft (PDX) model. (journal article) Zaffaroni, Nadia \| Frezza, Anna Maria \| Zuco, Valentina \| Gronchi, Alessandro \| Colombo, Chiara \| Pasquali, Sandro \| Casali, Paolo G. \| Tos, Angelo Paolo Dei \| Collini, Paola \| Pantaleo, Maria Abbondanza \| ... \| Stacchiotti, Silvia Journal of Clinical Oncology, volume 36 (2018). 10.1200/jco.2018.36.15_suppl.11578 Cited by (1) \| Cite \| Source
Synthesis and Evaluation of the Tumor Cell Growth Inhibitory Potential of New Putative HSP90 Inhibitors (journal article) Bizarro, Ana \| Sousa, Diana \| Lima, Raquel \| Musso, Loana \| Cincinelli, Raffaella \| Zuco, Vantina \| De Cesare, Michelandrea \| Dallavalle, Sabrina \| Vasconcelos, M. Molecules, volume 23, issue 2, pages 407- (2018). 10.3390/molecules23020407 Cited by (15) \| Cite \| Source \| Open Access
Evaluation of Mediators Associated with the Inflammatory Response in Prostate Cancer Patients Undergoing Radiotherapy (journal article) Bedini, Nice \| Cicchetti, Alessandro \| Palorini, Federica \| Magnani, Tiziana \| Zuco, Valentina \| Pennati, Marzia \| Campi, Elisa \| Allavena, Paola \| Pesce, Samantha \| Villa, Sergio \| ... \| Valdagni, Riccardo Disease Markers, volume 2018 (2018). 10.1155/2018/9128128 Cited by (12) \| Cite \| Source \| Open Access
Antitumor activity of miR-34a in peritoneal mesothelioma relies on c-MET and AXL inhibition: persistent activation of ERK and AKT signaling as a possible cytoprotective mechanism (journal article) El Bezawy, Rihan \| De Cesare, Michelandrea \| Pennati, Marzia \| Deraco, Marcello \| Gandellini, Paolo \| Zuco, Valentina \| Zaffaroni, Nadia Journal of Hematology & Oncology, volume 10, issue 1 (2017). 10.1186/s13045-016-0387-6 Cited by (37) \| Cite \| Source \| Open Access
Overcoming ABC transporter-mediated multidrug resistance: The dual role of tyrosine kinase inhibitors as multitargeting agents (journal article) Beretta, Giovanni Luca \| Cassinelli, Giuliana \| Pennati, Marzia \| Zuco, Valentina \| Gatti, Laura European Journal of Medicinal Chemistry, volume 142 (2017). 10.1016/j.ejmech.2017.07.062 Cited by (155) \| Cite \| Source