Xavier Deupi

ScholarGPS® ID: 65295628919266

Affiliation

Paul Scherrer Institut, Switzerland

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Metrics Summary

Publication Count

107

Predicted Citations

9,441

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

Add Delete
A tool for nuclear imaging of the SARS-CoV-2 entry receptor: molecular model and preclinical development of ACE2-selective radiopeptides (journal article) Beyer, Darja \| Vaccarin, Christian \| Deupi, Xavier \| Mapanao, Ana Katrina \| Cohrs, Susan \| Sozzi-Guo, Fan \| Grundler, Pascal V. \| van der Meulen, Nicholas P. \| Wang, Jinling \| Tanriver, Matthias \| ... \| Müller, Cristina EJNMMI Research, volume 13, issue 1 (2023). 10.1186/s13550-023-00979-2 Cited by (3) \| Cite \| Source
β-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the same GPCR in living cells (journal article) Haider, Raphael S. \| Matthees, Edda S. F. \| Drube, Julia \| Reichel, Mona \| Zabel, Ulrike \| Inoue, Asuka \| Chevigné, Andy \| Krasel, Cornelius \| Deupi, Xavier \| Hoffmann, Carsten Nature Communications, volume 13, issue 1 (2022). 10.1038/s41467-022-33307-8 Cited by (23) \| Cite \| Source
Structural Elements Directing G Proteins and β-Arrestin Interactions with the Human Melatonin Type 2 Receptor Revealed by Natural Variants (journal article) Plouffe, Bianca \| Karamitri, Angeliki \| Flock, Tilman \| Gallion, Jonathan M. \| Houston, Shane \| Daly, Carole A. \| Bonnefond, Amélie \| Guillaume, Jean-Luc \| Le Gouill, Christian \| Froguel, Phillipe \| ... \| Bouvier, Michel ACS Pharmacology & Translational Science, volume 5, issue 2, pages 89-101 (2022). 10.1021/acsptsci.1c00239 Cited by (2) \| Cite \| Source
Chimeric single α-helical domains as rigid fusion protein connections for protein nanotechnology and structural biology (journal article) Collu, Gabriella \| Bierig, Tobias \| Krebs, Anna-Sophia \| Engilberge, Sylvain \| Varma, Niveditha \| Guixà-González, Ramon \| Sharpe, Timothy \| Deupi, Xavier \| Olieric, Vincent \| Poghosyan, Emiliya \| Benoit, Roger M. Structure, volume 30, issue 1, pages 95-106.e7 (2022). 10.1016/j.str.2021.09.002 Cited by (4) \| Cite \| Source
Exploring the signaling space of a GPCR using bivalent ligands with a rigid oligoproline backbone (journal article) Romantini, Nina \| Alam, Shahidul \| Dobitz, Stefanie \| Spillmann, Martin \| De Foresta, Martina \| Schibli, Roger \| Schertler, Gebhard F. X. \| Wennemers, Helma \| Deupi, Xavier \| Behe, Martin \| Berger, Philipp Proceedings of the National Academy of Sciences, volume 118, issue 48 (2021). 10.1073/pnas.2108776118 Cited by (6) \| Cite \| Source
Unraveling binding mechanism and kinetics of macrocyclic Gαq protein inhibitors (journal article) Voss, Jan H. \| Nagel, Jessica \| Rafehi, Muhammad \| Guixà-González, Ramon \| Malfacini, Davide \| Patt, Julian \| Kehraus, Stefan \| Inoue, Asuka \| König, Gabriele M. \| Kostenis, Evi \| ... \| Müller, Christa E. Pharmacological Research, volume 173 (2021). 10.1016/j.phrs.2021.105880 Cited by (10) \| Cite \| Source
Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants (journal article) Hegron, Alan \| Huh, Eunna \| Deupi, Xavier \| Sokrat, Badr \| Gao, Wenwen \| Le Gouill, Christian \| Canouil, Mickaël \| Boissel, Mathilde \| Charpentier, Guillaume \| Roussel, Ronan \| ... \| Bouvier, Michel ACS Pharmacology & Translational Science, volume 4, issue 5, pages 1614-1627 (2021). 10.1021/acsptsci.1c00157 Cited by (5) \| Cite \| Source
High-mass MALDI-MS unravels ligand-mediated G protein–coupling selectivity to GPCRs (journal article) Wu, Na \| Olechwier, Agnieszka M. \| Brunner, Cyrill \| Edwards, Patricia C. \| Tsai, Ching-Ju \| Tate, Christopher G. \| Schertler, Gebhard F. X. \| Schneider, Gisbert \| Deupi, Xavier \| Zenobi, Renato \| Ma, Pikyee Proceedings of the National Academy of Sciences, volume 118, issue 31 (2021). 10.1073/pnas.2024146118 Cited by (10) \| Cite \| Source
Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist (journal article) Isaikina, Polina \| Tsai, Ching-Ju \| Dietz, Nikolaus \| Pamula, Filip \| Grahl, Anne \| Goldie, Kenneth N. \| Guixà-González, Ramon \| Branco, Camila \| Paolini-Bertrand, Marianne \| Calo, Nicolas \| ... \| Grzesiek, Stephan Science Advances, volume 7, issue 25 (2021). 10.1126/sciadv.abg8685 Cited by (39) \| Cite \| Source
An experimental strategy to probe Gq contribution to signal transduction in living cells (journal article) Patt, Julian \| Alenfelder, Judith \| Pfeil, Eva Marie \| Voss, Jan Hendrik \| Merten, Nicole \| Eryilmaz, Funda \| Heycke, Nina \| Rick, Uli \| Inoue, Asuka \| Kehraus, Stefan \| ... \| Kostenis, Evi Journal of Biological Chemistry, volume 296 (2021). 10.1016/j.jbc.2021.100472 Cited by (19) \| Cite \| Source
Distance-Dependent Cellular Uptake of Oligoproline-Based Homobivalent Ligands Targeting GPCRs—An Experimental and Computational Analysis (journal article) Dobitz, Stefanie \| Wilhelm, Patrick \| Romantini, Nina \| De Foresta, Martina \| Walther, Cornelia \| Ritler, Andreas \| Schibli, Roger \| Berger, Philipp \| Deupi, Xavier \| Béhé, Martin \| Wennemers, Helma Bioconjugate Chemistry, volume 31, issue 10, pages 2431-2438 (2020). 10.1021/acs.bioconjchem.0c00484 Cited by (5) \| Cite \| Source
Femtosecond-to-millisecond structural changes in a light-driven sodium pump (journal article) Skopintsev, Petr \| Ehrenberg, David \| Weinert, Tobias \| James, Daniel \| Kar, Rajiv K. \| Johnson, Philip J. M. \| Ozerov, Dmitry \| Furrer, Antonia \| Martiel, Isabelle \| Dworkowski, Florian \| ... \| Standfuss, Jörg Nature, volume 583, issue 7815, pages 314-318 (2020). 10.1038/s41586-020-2307-8 Cited by (122) \| Cite \| Source
Triazolo-Peptidomimetics: Novel Radiolabeled Minigastrin Analogs for Improved Tumor Targeting (journal article) Grob, Nathalie M. \| Häussinger, Daniel \| Deupi, Xavier \| Schibli, Roger \| Behe, Martin \| Mindt, Thomas L. Journal of Medicinal Chemistry, volume 63, issue 9, pages 4484-4495 (2020). 10.1021/acs.jmedchem.9b01936 Cited by (22) \| Cite \| Source
Crystal structure of jumping spider rhodopsin-1 as a light sensitive GPCR (journal article) Varma, Niranjan \| Mutt, Eshita \| Mühle, Jonas \| Panneels, Valérie \| Terakita, Akihisa \| Deupi, Xavier \| Nogly, Przemyslaw \| Schertler, Gebhard F. X. \| Lesca, Elena Proceedings of the National Academy of Sciences, volume 116, issue 29, pages 14547-14556 (2019). 10.1073/pnas.1902192116 Cited by (42) \| Cite \| Source
Cryo-EM structure of the rhodopsin-Gαi-βγ complex reveals binding of the rhodopsin C-terminal tail to the gβ subunit (journal article) Tsai, Ching-Ju \| Marino, Jacopo \| Adaixo, Ricardo \| Pamula, Filip \| Muehle, Jonas \| Maeda, Shoji \| Flock, Tilman \| Taylor, Nicholas MI \| Mohammed, Inayatulla \| Matile, Hugues \| ... \| Schertler, Gebhard eLife, volume 8 (2019). 10.7554/eLife.46041 Cited by (47) \| Cite \| Source
The counterion–retinylidene Schiff base interaction of an invertebrate rhodopsin rearranges upon light activation (journal article) Nagata, Takashi \| Koyanagi, Mitsumasa \| Tsukamoto, Hisao \| Mutt, Eshita \| Schertler, Gebhard F. X. \| Deupi, Xavier \| Terakita, Akihisa Communications Biology, volume 2, issue 1 (2019). 10.1038/s42003-019-0409-3 Cited by (28) \| Cite \| Source
The Two-Photon Reversible Reaction of the Bistable Jumping Spider Rhodopsin-1 (journal article) Ehrenberg, David \| Varma, Niranjan \| Deupi, Xavier \| Koyanagi, Mitsumasa \| Terakita, Akihisa \| Schertler, Gebhard F.X. \| Heberle, Joachim \| Lesca, Elena Biophysical Journal, volume 116, issue 7, pages 1248-1258 (2019). 10.1016/j.bpj.2019.02.025 Cited by (17) \| Cite \| Source
Elucidating the Structure–Activity Relationship of the Pentaglutamic Acid Sequence of Minigastrin with Cholecystokinin Receptor Subtype 2 (journal article) Ritler, Andreas \| Shoshan, Michal S. \| Deupi, Xavier \| Wilhelm, Patrick \| Schibli, Roger \| Wennemers, Helma \| Béhé, Martin Bioconjugate Chemistry, volume 30, issue 3, pages 657-666 (2019). 10.1021/acs.bioconjchem.8b00849 Cited by (12) \| Cite \| Source
Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation (journal article) Mayer, Daniel \| Damberger, Fred F. \| Samarasimhareddy, Mamidi \| Feldmueller, Miki \| Vuckovic, Ziva \| Flock, Tilman \| Bauer, Brian \| Mutt, Eshita \| Zosel, Franziska \| Allain, Frédéric H. T. \| ... \| Veprintsev, Dmitry B. Nature Communications, volume 10, issue 1 (2019). 10.1038/s41467-019-09204-y Cited by (80) \| Cite \| Source
An online resource for GPCR structure determination and analysis (journal article) Munk, Christian \| Mutt, Eshita \| Isberg, Vignir \| Nikolajsen, Louise F. \| Bibbe, Janne M. \| Flock, Tilman \| Hanson, Michael A. \| Stevens, Raymond C. \| Deupi, Xavier \| Gloriam, David E. Nature Methods, volume 16, issue 2, pages 151-162 (2019). 10.1038/s41592-018-0302-x Cited by (100) \| Cite \| Source