Kenichi Akaji | Scholar Profiles and Rankings

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Stabilization of CDK6 by ribosomal protein uS7, a target protein of the natural product fucoxanthinol (journal article) Iizumi, Yosuke \| Sowa, Yoshihiro \| Goi, Wakana \| Aono, Yuichi \| Watanabe, Motoki \| Kurumida, Yoichi \| Kameda, Tomoshi \| Akaji, Kenichi \| Kitagawa, Masatoshi \| Sakai, Toshiyuki Communications Biology, volume 5, issue 1 (2022). 10.1038/s42003-022-03522-6 Cited by (1) \| Cite \| Source
The Effects of Side-Chain Configurations of a Retro–Inverso-Type Inhibitor on the Human T-Cell Leukemia Virus (HTLV)-1 Protease (journal article) Awahara, Chiyuki \| Oku, Daiki \| Furuta, Saki \| Kobayashi, Kazuya \| Teruya, Kenta \| Akaji, Kenichi \| Hattori, Yasunao Molecules, volume 27, issue 5, pages 1646- (2022). 10.3390/molecules27051646 Cited by (4) \| Cite \| Source
Synthesis and Structural Optimization of Macrocyclic BACE1 Inhibitors with a Hydrophobic Cross-Linked Structure (conference) Kobayashi, Kazuya \| Otani, Takuya \| Hattori, Yasunao \| Akaji, Kenichi 36th European Peptide Symposium (2022) 10.17952/36EPS.2022.137 Cite \| Source
Synthesis and Structural Optimization of Macrocyclic BACE1 Inhibitors with a Hydrophobic Cross-Linked Structure (conference) Kobayashi, Kazuya \| Otani, Takuya \| Hattori, Yasunao \| Akaji, Kenichi 36th European Peptide Symposium (2022) 10.17952/36EPS/36EPS.2022.137 Cite \| Source
Macrocyclic BACE1 inhibitors with hydrophobic cross-linked structures: Optimization of ring size and ring structure (journal article) Otani, Takuya \| Hattori, Yasunao \| Akaji, Kenichi \| Kobayashi, Kazuya Bioorganic & Medicinal Chemistry, volume 52 (2021). 10.1016/j.bmc.2021.116517 Cited by (1) \| Cite \| Source
Structure–activity relationship study of hydroxyethylamine isostere and P1′ site structure of peptide mimetic BACE1 inhibitors (journal article) Kobayashi, Kazuya \| Otani, Takuya \| Ijiri, Saki \| Kawasaki, Yuki \| Matsubara, Hiroki \| Miyagi, Takahiro \| Kitajima, Taishi \| Iseki, Risa \| Ishizawa, Katsuyasu \| Shindo, Naoka \| ... \| Akaji, Kenichi Bioorganic & Medicinal Chemistry, volume 50 (2021). 10.1016/j.bmc.2021.116459 Cited by (2) \| Cite \| Source
Studies on Functional Molecules Based on Peptide Chemistry (journal article) Akaji, Kenichi YAKUGAKU ZASSHI, volume 141, issue 2, pages 215-233 (2021). 10.1248/yakushi.20-00209 Cite \| Source
Preparation of SARS-CoV 3CL Protease and Synthesis of its Inhibitors (journal article) Konno, Hiroyuki \| Akaji, Kenichi Journal of Synthetic Organic Chemistry, Japan, volume 79, issue 1, pages 2-10 (2021). 10.5059/yukigoseikyokaishi.79.2 Cite \| Source
Design, synthesis, biological evaluation and in silico studies of certain aryl sulfonyl hydrazones conjugated with 1,3-diaryl pyrazoles as potent metallo-β-lactamase inhibitors (journal article) Shaaban, Marwa M. \| Ragab, Hanan M. \| Akaji, Kenichi \| McGeary, Ross P. \| Bekhit, Alaa-Eldin A. \| Hussein, Waleed M. \| Kurz, Julia L. \| Elwakil, Bassma H. \| Bekhit, Salma A. \| Ibrahim, Tamer M. \| ... \| Bekhit, Adnan A. Bioorganic Chemistry, volume 105 (2020). 10.1016/j.bioorg.2020.104386 Cited by (18) \| Cite \| Source
Enhancement of direct membrane penetration of arginine-rich peptides by polyproline II helix structure (journal article) Ohgita, Takashi \| Takechi-Haraya, Yuki \| Okada, Keisuke \| Matsui, Saki \| Takeuchi, Misaki \| Saito, Chihiro \| Nishitsuji, Kazuchika \| Uchimura, Kenji \| Kawano, Ryuji \| Hasegawa, Koki \| ... \| Saito, Hiroyuki Biochimica et Biophysica Acta (BBA) - Biomembranes, volume 1862, issue 10, pages 183403- (2020). 10.1016/j.bbamem.2020.183403 Cited by (15) \| Cite \| Source
Design and Evaluation of Anti-SARS-Coronavirus Agents Based on Molecular Interactions with the Viral Protease (journal article) Akaji, Kenichi \| Konno, Hiroyuki Molecules, volume 25, issue 17, pages 3920- (2020). 10.3390/molecules25173920 Cited by (18) \| Cite \| Source
Evaluation of an octahydroisochromene scaffold used as a novel SARS 3CL protease inhibitor (journal article) Yoshizawa, Shin-ichiro \| Hattori, Yasunao \| Kobayashi, Kazuya \| Akaji, Kenichi Bioorganic & Medicinal Chemistry, volume 28, issue 4, pages 115273- (2020). 10.1016/j.bmc.2019.115273 Cited by (20) \| Cite \| Source
A novel amphipathic cell-penetrating peptide based on the N-terminal glycosaminoglycan binding region of human apolipoprotein E (journal article) Ohgita, Takashi \| Takechi-Haraya, Yuki \| Nadai, Ryo \| Kotani, Mana \| Tamura, Yuki \| Nishikiori, Karin \| Nishitsuji, Kazuchika \| Uchimura, Kenji \| Hasegawa, Koki \| Sakai-Kato, Kumiko \| ... \| Saito, Hiroyuki Biochimica et Biophysica Acta (BBA) - Biomembranes, volume 1861, issue 3, pages 541-549 (2019). 10.1016/j.bbamem.2018.12.010 Cited by (20) \| Cite \| Source
Convergent Synthesis of <i>trans</i>-2,6-Disubstituted Piperidine Alkaloid, (−)-<i>iso</i>-6-Spectaline by Palladium-Catalyzed Cyclization (journal article) Kameda, Risako \| Sohma, Takuto \| Kobayashi, Kazuya \| Uchiyama, Ryosuke \| Nosaka, Kazuto \| Konno, Hiroyuki \| Akaji, Kenichi \| Hattori, Yasunao Chemical and Pharmaceutical Bulletin, volume 67, issue 3, pages 253-257 (2019). 10.1248/cpb.c18-00817 Cited by (3) \| Cite \| Source
Evaluation of a non-prime site substituent and warheads combined with a decahydroisoquinolin scaffold as a SARS 3CL protease inhibitor (journal article) Ohnishi, Kouji \| Hattori, Yasunao \| Kobayashi, Kazuya \| Akaji, Kenichi Bioorganic & Medicinal Chemistry, volume 27, issue 2, pages 425-435 (2019). 10.1016/j.bmc.2018.12.019 Cited by (23) \| Cite \| Source
Use of a Compact Tripodal Tris(bipyridine) Ligand to Stabilize a Single-Metal-Centered Chirality: Stereoselective Coordination of Iron(II) and Ruthenium(II) on a Semirigid Hexapeptide Macrocycle (journal article) Kobayashi, Yuka \| Hoshino, Masaru \| Kameda, Tomoshi \| Kobayashi, Kazuya \| Akaji, Kenichi \| Inuki, Shinsuke \| Ohno, Hiroaki \| Oishi, Shinya Inorganic Chemistry, volume 57, issue 9, pages 5475-5485 (2018). 10.1021/acs.inorgchem.8b00416 Cited by (7) \| Cite \| Source
Structure–Activity Relationship Study of Cyclic Pentapeptide Ligands for Atypical Chemokine Receptor 3 (ACKR3) (journal article) Sekiguchi, Haruka \| Kuroyanagi, Tomoko \| Rhainds, David \| Kobayashi, Kazuya \| Kobayashi, Yuka \| Ohno, Hiroaki \| Heveker, Nikolaus \| Akaji, Kenichi \| Fujii, Nobutaka \| Oishi, Shinya Journal of Medicinal Chemistry, volume 61, issue 8, pages 3745-3751 (2018). 10.1021/acs.jmedchem.8b00336 Cited by (3) \| Cite \| Source
ペプチド化学を基盤とするプロテアーゼ阻害剤の設計 (journal article) Akaji, Kenichi KAGAKU TO SEIBUTSU, volume 56, issue 10, pages 686-691 (2018). 10.1271/kagakutoseibutsu.56.686 Cite \| Source
Effects of replacement and addition of an amino acid contained in a cyclic peptide corresponding to a β ‐hairpin loop sequence of human EGF receptor (journal article) Kobayashi, Kazuya \| Mizuguchi, Takaaki \| Hattori, Yasunao \| Ohara, Naho \| Ninomiya, Ryunosuke \| Iida, Mika \| Ooe, Honami \| Yamazaki, Yukako \| Takata, Minami \| Tamamura, Hirokazu \| Akaji, Kenichi Journal of Peptide Science, volume 23, issue 7-8, pages 581-586 (2017). 10.1002/psc.3004 Cited by (1) \| Cite \| Source
Immunochemical Approach for Monitoring of Structural Transition of ApoA-I upon HDL Formation Using Novel Monoclonal Antibodies (journal article) Kimura, Hitoshi \| Mikawa, Shiho \| Mizuguchi, Chiharu \| Horie, Yuki \| Morita, Izumi \| Oyama, Hiroyuki \| Ohgita, Takashi \| Nishitsuji, Kazuchika \| Takeuchi, Atsuko \| Lund-Katz, Sissel \| ... \| Saito, Hiroyuki Scientific Reports, volume 7, issue 1 (2017). 10.1038/s41598-017-03208-8 Cited by (2) \| Cite \| Source \| Open Access