Irving L. Weissman | Scholar Profiles and Rankings

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CD47 Blockade Leads to Chemokine-Dependent Monocyte Infiltration and Loss of B Cells from the Splenic Marginal Zone (journal article) Yiu, Ying Ying \| Hansen, Paige S. \| Torrez Dulgeroff, Laughing Bear \| Blacker, Grace \| Myers, Lara \| Galloway, Sarah \| Gars, Eric \| Colace, Olivia \| Mansfield, Paul \| Hasenkrug, Kim J. \| ... \| Tal, Michal Caspi The Journal of Immunology, volume 208, issue 6, pages 1371-1377 (2022). 10.4049/jimmunol.2100352 Cite \| Source
PNP Hydrogel Prevents Formation of Symblephara in Mice After Ocular Alkali Injury (journal article) Swarup, Aditi \| Grosskopf, Abigail K. \| Stapleton, Lindsay M. \| Subramaniam, Varun R. \| Li, BaoXiang \| Weissman, Irving L. \| Appel, Eric A. \| Wu, Albert Y. Translational Vision Science & Technology, volume 11, issue 2, pages 31- (2022). 10.1167/tvst.11.2.31 Cite \| Source
Clonal Expansion of Stem/Progenitor Cells in Cancer, Fibrotic Diseases, and Atherosclerosis, and CD47 Protection of Pathogenic Cells (journal article) Majeti, R. \| Jamieson, C. \| Pang, W.W. \| Jaiswal, S. \| Leeper, N.J. \| Wernig, G. \| Weissman, I.L. Annual Review of Medicine, volume 73, issue 1, pages 307-320 (2022). 10.1146/annurev-med-042420-104436 Cited by (2) \| Cite \| Source
CD47 expression attenuates Ebola virus-induced immunopathology in mice (journal article) Rao, Deepashri \| O'Donnell, Kyle L. \| Carmody, Aaron \| Weissman, Irving L. \| Hasenkrug, Kim J. \| Marzi, Andrea Antiviral Research, volume 197 (2022). 10.1016/j.antiviral.2021.105226 Cite \| Source
261 A functional genetic screen uncovers regulators of intratumoral macrophage function and reveals CD24 as a novel target for cancer immunotherapy by macrophages (journal article) Barkal, Amira \| Brewer, Rachel \| Weissman, Irving Journal for ImmunoTherapy of Cancer, volume 9, issue Suppl 2, pages A283-A283 (2021). 10.1136/jitc-2021-SITC2021.261 Cite \| Source
Inter-cellular CRISPR screens reveal regulators of cancer cell phagocytosis (journal article) Kamber, Roarke A. \| Nishiga, Yoko \| Morton, Bhek \| Banuelos, Allison M. \| Barkal, Amira A. \| Vences-Catalán, Felipe \| Gu, Mingxin \| Fernandez, Daniel \| Seoane, Jose A. \| Yao, David \| ... \| Bassik, Michael C. Nature, volume 597, issue 7877, pages 549-554 (2021). 10.1038/s41586-021-03879-4 Cited by (55) \| Cite \| Source
Articular cartilage regeneration by activated skeletal stem cells (journal article) Murphy, Matthew P \| Koepke, Lauren S \| Lopez, Michael T \| Tong, Xinming \| Ambrosi, Thomas H \| Gulati, Gunsagar S \| Marecic, Owen \| Wang, Yuting \| Ransom, Ryan C \| Hoover, Malachia Y \| ... \| Chan, Charles K F Yearbook of Paediatric Endocrinology (2021). 10.1530/ey.18.5.9 Cite \| Source
Aged skeletal stem cells generate an inflammatory degenerative niche (journal article) Ambrosi, Thomas H. \| Marecic, Owen \| McArdle, Adrian \| Sinha, Rahul \| Gulati, Gunsagar S. \| Tong, Xinming \| Wang, Yuting \| Steininger, Holly M. \| Hoover, Malachia Y. \| Koepke, Lauren S. \| ... \| Chan, Charles K. F. Nature, volume 597, issue 7875, pages 256-262 (2021). 10.1038/s41586-021-03795-7 Cited by (92) \| Cite \| Source
Epidermal-Derived Hedgehog Signaling Drives Mesenchymal Proliferation during Digit Tip Regeneration (journal article) Maan, Zeshaan N. \| Rinkevich, Yuval \| Barrera, Janos \| Chen, Kellen \| Henn, Dominic \| Foster, Deshka \| Bonham, Clark Andrew \| Padmanabhan, Jagannath \| Sivaraj, Dharshan \| Duscher, Dominik \| ... \| Gurtner, Geoffrey C. Journal of Clinical Medicine, volume 10, issue 18, pages 4261- (2021). 10.3390/jcm10184261 Cited by (1) \| Cite \| Source
Absence of CD11a Expression Identifies Embryonic Hematopoietic Stem Cell Precursors via Competitive Neonatal Transplantation Assay (journal article) Karimzadeh, Alborz \| Varady, Erika S. \| Scarfone, Vanessa M. \| Chao, Connie \| Grathwohl, Karin \| Nguyen, Pauline U. \| Ghorbanian, Yasamine \| Weissman, Irving L. \| Serwold, Thomas \| Inlay, Matthew A. Frontiers in Cell and Developmental Biology, volume 9 (2021). 10.3389/fcell.2021.734176 Cite \| Source
Combining CD47 blockade with trastuzumab eliminates HER2-positive breast cancer cells and overcomes trastuzumab tolerance (journal article) Upton, Rosalynd \| Banuelos, Allison \| Feng, Dongdong \| Biswas, Tanuka \| Kao, Kevin \| McKenna, Kelly \| Willingham, Stephen \| Ho, Po Yi \| Rosental, Benyamin \| Tal, Michal Caspi \| ... \| Weissman, Irving L. Proceedings of the National Academy of Sciences, volume 118, issue 29 (2021). 10.1073/pnas.2026849118 Cited by (49) \| Cite \| Source
Distinct skeletal stem cell types orchestrate long bone skeletogenesis (journal article) Ambrosi, Thomas H \| Sinha, Rahul \| Steininger, Holly M \| Hoover, Malachia Y \| Murphy, Matthew P \| Koepke, Lauren S \| Wang, Yuting \| Lu, Wan-Jin \| Morri, Maurizio \| Neff, Norma F \| ... \| Chan, Charles KF eLife, volume 10 (2021). 10.7554/eLife.66063 Cited by (22) \| Cite \| Source
Overexpression of CD47 is associated with brain overgrowth and 16p11.2 deletion syndrome (journal article) Li, Jingling \| Brickler, Thomas \| Banuelos, Allison \| Marjon, Kristopher \| Shcherbina, Anna \| Banerjee, Sravani \| Bian, Jing \| Narayanan, Cyndhavi \| Weissman, Irving L. \| Chetty, Sundari Proceedings of the National Academy of Sciences, volume 118, issue 15 (2021). 10.1073/pnas.2005483118 Cited by (8) \| Cite \| Source
Effects of Ultra-high doserate FLASH Irradiation on the Tumor Microenvironment in Lewis Lung Carcinoma: Role of Myosin Light Chain (journal article) Kim, Young-Eun \| Gwak, Seung-Hee \| Hong, Beom-Ju \| Oh, Jung-Min \| Choi, Hyung-Seok \| Kim, Myeoung Su \| Oh, Dawit \| Lartey, Frederik M. \| Rafat, Marjan \| Schüler, Emil \| ... \| Ahn, G-One International Journal of Radiation OncologyBiologyPhysics, volume 109, issue 5, pages 1440-1453 (2021). 10.1016/j.ijrobp.2020.11.012 Cited by (32) \| Cite \| Source
CD47 blockade reduces the pathologic features of experimental cerebral malaria and promotes survival of hosts with Plasmodium infection (journal article) Torrez Dulgeroff, Laughing Bear \| Oakley, Miranda S. \| Tal, Michal C. \| Yiu, Ying Ying \| He, Joy Q. \| Shoham, Maia \| Majam, Victoria \| Okoth, Winter A. \| Malla, Pallavi \| Kumar, Sanjai \| Weissman, Irving L. Proceedings of the National Academy of Sciences, volume 118, issue 11 (2021). 10.1073/pnas.1907653118 Cited by (5) \| Cite \| Source
Reactivation of the pluripotency program precedes formation of the cranial neural crest (journal article) Zalc, Antoine \| Sinha, Rahul \| Gulati, Gunsagar S. \| Wesche, Daniel J. \| Daszczuk, Patrycja \| Swigut, Tomek \| Weissman, Irving L. \| Wysocka, Joanna Science, volume 371, issue 6529 (2021). 10.1126/science.abb4776 Cited by (56) \| Cite \| Source
Hoxb5 defines the heterogeneity of self-renewal capacity in the hematopoietic stem cell compartment (journal article) Sakamaki, Taro \| Kao, Kevin S. \| Nishi, Katsuyuki \| Chen, James Y. \| Sadaoka, Kay \| Fujii, Momo \| Takaori-Kondo, Akifumi \| Weissman, Irving L. \| Miyanishi, Masanori Biochemical and Biophysical Research Communications, volume 539 (2021). 10.1016/j.bbrc.2020.12.077 Cited by (9) \| Cite \| Source
Effect of CD47 Blockade on Vascular Inflammation (journal article) Jarr, Kai-Uwe \| Nakamoto, Ryusuke \| Doan, Brandon H. \| Kojima, Yoko \| Weissman, Irving L. \| Advani, Ranjana H. \| Iagaru, Andrei \| Leeper, Nicholas J. New England Journal of Medicine, volume 384, issue 4, pages 382-383 (2021). 10.1056/NEJMc2029834 Cited by (36) \| Cite \| Source
Wounds Inhibit Tumor Growth In Vivo (journal article) Hu, Michael S. \| Maan, Zeshaan N. \| Leavitt, Tripp \| Hong, Wan Xing \| Rennert, Robert C. \| Marshall, Clement D. \| Borrelli, Mimi R. \| Zhu, Ted N. \| Esquivel, Mikaela \| Zimmermann, Andrew \| ... \| Longaker, Michael T. Annals of Surgery, volume 273, issue 1, pages 173-180 (2021). 10.1097/SLA.0000000000003255 Cited by (2) \| Cite \| Source
Safe and Effective In Vivo Targeting and Gene Editing in Hematopoietic Stem Cells: Strategies for Accelerating Development (journal article) Cannon, Paula \| Asokan, Aravind \| Czechowicz, Agnieszka \| Hammond, Paula \| Kohn, Donald B. \| Lieber, Andre \| Malik, Punam \| Marks, Peter \| Porteus, Matthew \| Verhoeyen, Els \| ... \| Kiem, Hans-Peter Human Gene Therapy, volume 32, issue 1-2, pages 31-42 (2021). 10.1089/hum.2020.263 Cited by (13) \| Cite \| Source

Title	Investigators	Year	Expiration	Amount
Confocal microscopy at Hopkins Marine Station	Block, Barbara \| Lowe, Christopher \| Weissman, Irving \| Palumbi, Stephen \| Gilly, William	08-01-2012	07-31-2013	$344,376
Marine Biotech Fellowship: The Population Genetic Consequences of Histocompatibility in a Colonial Ascidian	Stoner, Douglas \| Weissman, Irving	10-01-1992	03-31-1995	$84,000
Does Botryllus Possess the Machinery for Recombination Signal Sequence Directed Gene Rearrangement?	Weissman, Irving	06-15-1990	11-30-1991	$49,808
Genetic and Molecular Systems Controlling Allogeneic Tissue Reactivity in Protochordates	Abbott, Donald \| Weissman, Irving	08-15-1978	01-31-1981	$45,179

Title	Investigators	Year	Cost	Agency
Programmed Cell Removal (PrCR) by Macrophages: recognition and phagocytosis of target cells	Weissman, Irving L.	2020	$404,694	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Cellular and molecular analyses of hematopoietic stem cell [HSC] interactions with bone marrow niches to improve HSC engraftment for transplantation and tolerance induction	Weissman, Irving L.	2020	$374,965	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Graduate Training in Stem Cell Biology and Regenerative Medicine	Weissman, Irving L.	2020	$482,056	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Evolutionary Conserved Mechanisms of Neuronal Degeneration and Regeneration	Weissman, Irving L.	2020	$433,675	NATIONAL INSTITUTE ON AGING
Stem Cell Biology, Cancer Stem Cell Biology, and Cancer Immunotherapy	Weissman, Irving L.	2020	$937,462	NATIONAL CANCER INSTITUTE
Graduate Training in Stem Cell Biology and Regenerative Medicine	Weissman, Irving L.	2019	$428,952	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Genes, cells, and pathways that regulate urochordate allogeneic stem cell competition and their mammalian homologues	Weissman, Irving L.	2019	$351,742	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Stem Cell Biology, Cancer Stem Cell Biology, and Cancer Immunotherapy	Weissman, Irving L.	2019	$981,896	NATIONAL CANCER INSTITUTE
Cellular and molecular analyses of hematopoietic stem cell [HSC] interactions with bone marrow niches to improve HSC engraftment for transplantation and tolerance induction	Weissman, Irving L.	2019	$374,333	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Genes, cells, and pathways that regulate urochordate allogeneic stem cell competition and their mammalian homologues	Weissman, Irving L.	2018	$351,420	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Stem Cell Biology, Cancer Stem Cell Biology, and Cancer Immunotherapy	Weissman, Irving L.	2018	$1,010,214	NATIONAL CANCER INSTITUTE
Cellular and molecular analyses of hematopoietic stem cell [HSC] interactions with bone marrow niches to improve HSC engraftment for transplantation and tolerance induction	Weissman, Irving L.	2018	$369,622	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Stem Cell Biology, Cancer Stem Cell Biology, and Cancer Immunotherapy	Weissman, Irving L.	2018	$105,661	NATIONAL CANCER INSTITUTE
HSC Diversity, in aging, ontogeny, and transformation	Weissman, Irving L.	2017	$410,288	NATIONAL CANCER INSTITUTE
Genes, cells, and pathways that regulate urochordate allogeneic stem cell competition and their mammalian homologues	Weissman, Irving L.	2017	$351,121	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Stem Cell Biology, Cancer Stem Cell Biology, and Cancer Immunotherapy	Weissman, Irving L.	2017	$693,152	NATIONAL CANCER INSTITUTE
HSC Diversity, in aging, ontogeny, and transformation	Weissman, Irving L.	2017	$105,661	NATIONAL CANCER INSTITUTE
Genes, cells, and pathways that regulate urochordate allogeneic stem cell competition and their mammalian homologues	Weissman, Irving L.	2016	$350,835	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
HSC Diversity, in aging, ontogeny, and transformation	Weissman, Irving L.	2016	$409,775	NATIONAL CANCER INSTITUTE
A search for genes that regulate allogeneic stem cell competition	Weissman, Irving L.	2015	$350,244	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Molecular Characterization of Acute Myeloid Leukemia	Weissman, Irving L.	2015	$393,893	NATIONAL CANCER INSTITUTE
Interrogation of individual cells to identify progenitors and their niches	Weissman, Irving L.	2015	$1,118,367	NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
HSC Diversity, in aging, ontogeny, and transformation	Weissman, Irving L.	2015	$409,293	NATIONAL CANCER INSTITUTE
A search for genes that regulate allogeneic stem cell competition	Weissman, Irving L.	2014	$350,244	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Molecular Characterization of Acute Myeloid Leukemia	Weissman, Irving L.	2014	$381,066	NATIONAL CANCER INSTITUTE
Interrogation of individual cells to identify progenitors and their niches	Weissman, Irving L.	2014	$1,111,936	NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
HSC Diversity: Regulation by Clonal Selection vs Epigenetic Induction	Weissman, Irving L.	2014	$374,921	NATIONAL CANCER INSTITUTE
Cellular and molecular mechanisms of aging and regeneration in colonial chordate	Weissman, Irving L.	2014	$307,584	NATIONAL INSTITUTE ON AGING
Homing Receptor Determinants of HSC	Weissman, Irving L.	2013	$391,237	NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
Molecular Characterization of Acute Myeloid Leukemia	Weissman, Irving L.	2013	$368,319	NATIONAL CANCER INSTITUTE
HSC Diversity: Regulation by Clonal Selection vs Epigenetic Induction	Weissman, Irving L.	2013	$363,016	NATIONAL CANCER INSTITUTE
therapeutic Targeting of CD47 on Human Leukemia and Other Cancer Stem Cells	Weissman, Irving L.	2013	$385,366	NATIONAL CANCER INSTITUTE
A search for genes that regulate allogeneic stem cell competition	Weissman, Irving L.	2013	$337,987	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Interrogation of individual cells to identify progenitors and their niches	Weissman, Irving L.	2013	$1,020,905	NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
Cellular and molecular mechanisms of aging and regeneration in colonial chordate	Weissman, Irving L.	2013	$290,667	NATIONAL INSTITUTE ON AGING
A search for genes that regulate allogeneic stem cell competition	Weissman, Irving L.	2012	$344,279	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Homing Receptor Determinants of HSC	Weissman, Irving L.	2012	$410,388	NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
Molecular Characterization of Acute Myeloid Leukemia	Weissman, Irving L.	2012	$390,820	NATIONAL CANCER INSTITUTE
Interrogation of individual cells to identify progenitors and their niches	Weissman, Irving L.	2012	$1,133,311	NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
HSC Diversity: Regulation by Clonal Selection vs Epigenetic Induction	Weissman, Irving L.	2012	$385,871	NATIONAL CANCER INSTITUTE