Alberto Estevez

ScholarGPS® ID: 64323497801087

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Life Sciences

Discipline

Biology and Biological Sciences

Top Specialties

Antibody | Microscopy | Influenza

Metrics Summary

Publication Count

Predicted Citations

2,302

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration (journal article) Gerhardy, Stefan \| Ultsch, Mark \| Tang, Wanjian \| Green, Evan \| Holden, Jeffrey K. \| Li, Wei \| Estevez, Alberto \| Arthur, Chris \| Tom, Irene \| Rohou, Alexis \| Kirchhofer, Daniel Nature Communications, volume 13, issue 1 (2022). 10.1038/s41467-022-32760-9 Cited by (6) \| Cite \| Source
A Systematic Approach for Liposome and Lipodisk Preclinical Formulation Development by Microfluidic Technology (journal article) Levy, Elizabeth S. \| Yu, Jesse \| Estevez, Alberto \| Mao, Jialin \| Liu, Liling \| Torres, Elizabeth \| Leung, Dennis \| Yen, Chun-Wan The AAPS Journal, volume 23, issue 6 (2021). 10.1208/s12248-021-00651-4 Cited by (9) \| Cite \| Source
Imaging Reveals Importance of Shape and Flexibility for Glomerular Filtration of Biologics (journal article) Rafidi, Hanine \| Estevez, Alberto \| Ferl, Gregory Z. \| Mandikian, Danielle \| Stainton, Shannon \| Sermeño, Lauren \| Williams, Simon P. \| Kamath, Amrita V. \| Koerber, James T. \| Boswell, C. Andrew Molecular Cancer Therapeutics, volume 20, issue 10, pages 2008-2015 (2021). 10.1158/1535-7163.MCT-21-0116 Cited by (8) \| Cite \| Source
Impact of surfactant selection and incorporation on in situ nanoparticle formation from amorphous solid dispersions (journal article) Yen, Chun-Wan \| Kuhn, Robert \| Hu, Chloe \| Zhang, Wei \| Chiang, Po-Chang \| Chen, Jacob Z. \| Hau, Jonathan \| Estevez, Alberto \| Nagapudi, Karthik \| Leung, Dennis H. International Journal of Pharmaceutics, volume 607 (2021). 10.1016/j.ijpharm.2021.120980 Cited by (8) \| Cite \| Source
Automated high-throughput preparation and characterization of oligonucleotide-loaded lipid nanoparticles (journal article) Fan, Yuchen \| Yen, Chun-Wan \| Lin, Hsiu-Chao \| Hou, Weijia \| Estevez, Alberto \| Sarode, Apoorva \| Goyon, Alexandre \| Bian, Juan \| Lin, Jessica \| Koenig, Stefan G. \| ... \| Zhang, Kelly International Journal of Pharmaceutics, volume 599 (2021). 10.1016/j.ijpharm.2021.120392 Cited by (31) \| Cite \| Source
Bivalent antibody pliers inhibit β-tryptase by an allosteric mechanism dependent on the IgG hinge (journal article) Maun, Henry R. \| Vij, Rajesh \| Walters, Benjamin T. \| Morando, Ashley \| Jackman, Janet K. \| Wu, Ping \| Estevez, Alberto \| Chen, Xiaocheng \| Franke, Yvonne \| Lipari, Michael T. \| ... \| Koerber, James T. Nature Communications, volume 11, issue 1 (2020). 10.1038/s41467-020-20143-x Cited by (14) \| Cite \| Source
Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab (journal article) Rougé, Lionel \| Chiang, Nancy \| Steffek, Micah \| Kugel, Christine \| Croll, Tristan I. \| Tam, Christine \| Estevez, Alberto \| Arthur, Christopher P. \| Koth, Christopher M. \| Ciferri, Claudio \| ... \| Rohou, Alexis Science, volume 367, issue 6483, pages 1224-1230 (2020). 10.1126/science.aaz9356 Cited by (107) \| Cite \| Source
Targeted IgMs agonize ocular targets with extended vitreal exposure (journal article) Chen, Yvonne \| Paluch, Maciej \| Zorn, Julie A. \| Rajan, Sharmila \| Leonard, Brandon \| Estevez, Alberto \| Brady, John \| Chiu, Henry \| Phung, Wilson \| Famili, Amin \| ... \| Agard, Nicholas J. mAbs, volume 12, issue 1 (2020). 10.1080/19420862.2020.1818436 Cited by (3) \| Cite \| Source
Antigen physiochemical properties allosterically effect the IgG Fc-region and Fc neonatal receptor affinity (journal article) Sun, Yue \| Estevez, Alberto \| Schlothauer, Tilman \| Wecksler, Aaron T. mAbs, volume 12, issue 1 (2020). 10.1080/19420862.2020.1802135 Cited by (17) \| Cite \| Source
Production, characterization, and in vivo half-life extension of polymeric IgA molecules in mice (journal article) Lombana, T. Noelle \| Rajan, Sharmila \| Zorn, Julie A. \| Mandikian, Danielle \| Chen, Eugene C. \| Estevez, Alberto \| Yip, Victor \| Bravo, Daniel D. \| Phung, Wilson \| Farahi, Farzam \| ... \| Spiess, Christoph mAbs, volume 11, issue 6, pages 1122-1138 (2019). 10.1080/19420862.2019.1622940 Cited by (40) \| Cite \| Source
Building Cryo-EM at Genentech to Enable Research and Drug Discovery (journal article) Estevez, Alberto \| Arthur, Chris \| Rouge, Lionel \| Kschonsak, Marc \| Rohou, Alexis \| Ciferri, Claudio Microscopy and Microanalysis, volume 25, issue S2, pages 1314-1315 (2019). 10.1017/S143192761900730X Cited by (2) \| Cite \| Source
Optimizing the pharmacokinetic properties of polymeric IgA in mice (journal article) Rajan, Sharmila \| Lombaba, Noelle Twyla \| Mandikian, Danielle \| Boswell, Andy \| Yip, Victor \| Bravo-Perez, Daniel \| Chen, Eugene \| Wang, Jianyong \| Phung, Wilson \| Lee, Sophia \| ... \| Spiess, Christoph The Journal of Immunology, volume 202, issue 1_Supplement, pages 131.19-131.19 (2019). 10.4049/jimmunol.202.Supp.131.19 Cite \| Source
Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin (journal article) Xu, Hui \| Li, Tianbo \| Rohou, Alexis \| Arthur, Christopher P. \| Tzakoniati, Foteini \| Wong, Evera \| Estevez, Alberto \| Kugel, Christine \| Franke, Yvonne \| Chen, Jun \| ... \| Payandeh, Jian Cell, volume 176, issue 4, pages 702-715.e14 (2019). 10.1016/j.cell.2018.12.018 Cited by (121) \| Cite \| Source
Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9 (journal article) Holliday, Michael J. \| Ferrao, Ryan \| de Leon Boenig, Gladys \| Estevez, Alberto \| Helgason, Elizabeth \| Rohou, Alexis \| Dueber, Erin C. \| Fairbrother, Wayne J. Journal of Biological Chemistry, volume 293, issue 43, pages 16803-16817 (2018). 10.1074/jbc.RA118.004821 Cited by (8) \| Cite \| Source
Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9. (journal article) Holliday, M.J. \| Ferrao, R. \| Boenig, G. de Leon \| Estevez, A. \| Helgason, E. \| Rohou, A. \| Dueber, E.C. \| Fairbrother, W.J. Journal of Biological Chemistry, volume 293, issue 43, pages 16803-16817 (2018). 10.2210/pdb6e26/pdb Cite \| Source
Design of a High Capacity Puck Storage System for Cryo-EM grids in a Facility Setting (journal article) Estevez, Alberto \| Arthur, Chris \| Rohou, Alexis \| Ciferri, Claudio Microscopy and Microanalysis, volume 23, issue S1, pages 846-847 (2017). 10.1017/S1431927617004895 Cite \| Source \| Open Access
A broadly protective therapeutic antibody against influenza B virus with two mechanisms of action (journal article) Chai, Ning \| Swem, Lee R. \| Park, Summer \| Nakamura, Gerald \| Chiang, Nancy \| Estevez, Alberto \| Fong, Rina \| Kamen, Lynn \| Kho, Elviza \| Reichelt, Mike \| ... \| Tan, Man-Wah Nature Communications, volume 8, issue 1 (2017). 10.1038/ncomms14234 Cited by (53) \| Cite \| Source \| Open Access
GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes (journal article) Aglietti, Robin A. \| Estevez, Alberto \| Gupta, Aaron \| Ramirez, Monica Gonzalez \| Liu, Peter S. \| Kayagaki, Nobuhiko \| Ciferri, Claudio \| Dixit, Vishva M. \| Dueber, Erin C. Proceedings of the National Academy of Sciences, volume 113, issue 28, pages 7858-7863 (2016). 10.1073/pnas.1607769113 Cited by (674) \| Cite \| Source \| Open Access
EM by EM: High-Efficiency Epitope Mapping using High-Throughput Electron Microscopy (journal article) Estevez, Alberto \| Garvey, Colin \| Ciferri, Claudio Microscopy and Microanalysis, volume 22, issue S3, pages 1080-1081 (2016). 10.1017/S1431927616006243 Cite \| Source
The trimeric serine protease HtrA1 forms a cage-like inhibition complex with an anti-HtrA1 antibody (journal article) Ciferri, Claudio \| Lipari, Michael T. \| Liang, Wei-Ching \| Estevez, Alberto \| Hang, Julie \| Stawicki, Scott \| Wu, Yan \| Moran, Paul \| Elliott, Mike \| Eigenbrot, Charles \| ... \| Kirchhofer, Daniel Biochemical Journal, volume 472, issue 2, pages 169-181 (2015). 10.1042/BJ20150601 Cited by (19) \| Cite \| Source