William V. Murray | Scholar Profiles and Rankings

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Discovery of PEGylated 6-Benzhydryl-4-amino-quinazolines as Peripherally Restricted CB1 R Inverse Agonists (journal article) Zhang, Yue-Mei \| Greco, Michael \| Le Blanc, Tonya \| Lang, Wensheng \| Kauffman, Jack \| Masucci, John \| Murray, William V. \| Demarest, Keith \| Macielag, Mark Joseph ACS Medicinal Chemistry Letters, volume 11, issue 12, pages 2504-2509 (2020). 10.1021/acsmedchemlett.0c00495 Cite \| Source
6-Benzhydryl-4-amino-quinolin-2-ones as Potent Cannabinoid Type 1 (CB1 ) Receptor Inverse Agonists and Chemical Modifications for Peripheral Selectivity (journal article) Zhang, Yue-Mei \| Greco, Michael N. \| Macielag, Mark J. \| Teleha, Christopher A. \| DesJarlais, Renee L. \| Tang, Yuting \| Ho, George \| Hou, Cuifen \| Chen, Cailin \| Zhao, Shuyuan \| ... \| Leonard, James Journal of Medicinal Chemistry, volume 61, issue 22, pages 10276-10298 (2018). 10.1021/acs.jmedchem.8b01467 Cited by (13) \| Cite \| Source
Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors (journal article) Xu, Guozhang \| Gaul, Michael D. \| Kuo, Gee-Hong \| Du, Fuyong \| Xu, June Zhi \| Wallace, Nathaniel \| Hinke, Simon \| Kirchner, Thomas \| Silva, Jose \| Huebert, Norman D. \| ... \| Demarest, Keith Bioorganic & Medicinal Chemistry Letters, volume 28, issue 21, pages 3446-3453 (2018). 10.1016/j.bmcl.2018.09.025 Cited by (9) \| Cite \| Source
Erratum to “Discovery of N-arylpyrroles as agonists of GPR120 for the treatment of type II diabetes” Bioorg. Med. Chem. Lett. 28 (2018) [841–846] (journal article) Winters, Michael P. \| Sui, Zhihua \| Wall, Mark \| Wang, Yuanping \| Gunnet, Joseph \| Leonard, James \| Hua, Hong \| Yan, Wen \| Suckow, Arthur \| Bell, Austin \| ... \| Murray, William V. Bioorganic & Medicinal Chemistry Letters, volume 28, issue 9, pages 1676-1678 (2018). 10.1016/j.bmcl.2018.03.053 Cite \| Source
Synthesis and biological evaluation of benzocyclobutane-C-glycosides as potent and orally active SGLT1/SGLT2 dual inhibitors (journal article) Kuo, Gee-Hong \| Gaul, Micheal D. \| Liang, Yin \| Xu, June Z. \| Du, Fuyong \| Hornby, Pamela \| Xu, Guozhang \| Qi, Jenson \| Wallace, Nathaniel \| Lee, Seunghun \| ... \| Demarest, Keith Bioorganic & Medicinal Chemistry Letters, volume 28, issue 7, pages 1182-1187 (2018). 10.1016/j.bmcl.2018.02.057 Cited by (29) \| Cite \| Source
Discovery of N -arylpyrroles as agonists of GPR120 for the treatment of type II diabetes (journal article) Winters, Michael P. \| Sui, Zhihua \| Wall, Mark \| Wang, Yuanping \| Gunnet, Joseph \| Leonard, James \| Hua, Hong \| Yan, Wen \| Suckow, Arthur \| Bell, Austin \| ... \| Murray, William V. Bioorganic & Medicinal Chemistry Letters, volume 28, issue 5, pages 841-846 (2018). 10.1016/j.bmcl.2018.02.013 Cited by (16) \| Cite \| Source
Discovery of an Isothiazole-Based Phenylpropanoic Acid GPR120 Agonist as a Development Candidate for Type 2 Diabetes (journal article) Zhang, Xuqing \| Cai, Chaozhong \| Sui, Zhihua \| Macielag, Mark \| Wang, Yuanping \| Yan, Wen \| Suckow, Arthur \| Hua, Hong \| Bell, Austin \| Haug, Peter \| ... \| Murray, William V. ACS Medicinal Chemistry Letters, volume 8, issue 9, pages 947-952 (2017). 10.1021/acsmedchemlett.7b00233 Cited by (18) \| Cite \| Source
Design, synthesis and SAR of a novel series of heterocyclic phenylpropanoic acids as GPR120 agonists (journal article) Zhang, Xuqing \| Cai, Chaozhong \| Winters, Michael \| Wells, Michele \| Wall, Mark \| Lanter, James \| Sui, Zhihua \| Ma, Jingyuan \| Novack, Aaron \| Nashashibi, Imad \| ... \| Murray, William V. Bioorganic & Medicinal Chemistry Letters, volume 27, issue 15, pages 3272-3278 (2017). 10.1016/j.bmcl.2017.06.028 Cited by (19) \| Cite \| Source
Discovery of Orally Efficacious Tetrahydrobenzimidazoles as TGR5 Agonists for Type 2 Diabetes (journal article) Zhang, Xuqing \| Wall, Mark \| Sui, Zhihua \| Kauffman, Jack \| Hou, Cuifen \| Chen, Cailin \| Du, Fuyong \| Kirchner, Thomas \| Liang, Yin \| Johnson, Dana L. \| ... \| Demarest, Keith ACS Medicinal Chemistry Letters, volume 8, issue 5, pages 560-565 (2017). 10.1021/acsmedchemlett.7b00116 Cited by (8) \| Cite \| Source \| Open Access
Evaluation of anti-diabetic effect and gall bladder function with 2-thio-5-thiomethyl substituted imidazoles as TGR5 receptor agonists (journal article) Zhang, Xuqing \| Sui, Zhihua \| Kauffman, Jack \| Hou, Cuifen \| Chen, Cailin \| Du, Fuyong \| Kirchner, Thomas \| Liang, Yin \| Johnson, Dana \| Murray, William V. \| Demarest, Keith Bioorganic & Medicinal Chemistry Letters, volume 27, issue 8, pages 1760-1764 (2017). 10.1016/j.bmcl.2017.02.069 Cited by (15) \| Cite \| Source
ChemInform Abstract: Synthesis of β‐Substituted Cyclic Enones via Phosphonium Salt‐Activated, Palladium‐Catalyzed Cross‐Coupling of Cyclic 1,3‐Diones. (journal article) Yang, Shyh‐Ming \| Kuo, Gee‐Hong \| Gaul, Michael D. \| Murray, William V. ChemInform, volume 47, issue 34 (2016). 10.1002/chin.201634053 Cite \| Source
Synthesis of β-Substituted Cyclic Enones via Phosphonium Salt-Activated, Palladium-Catalyzed Cross-Coupling of Cyclic 1,3-Diones (journal article) Yang, Shyh-Ming \| Kuo, Gee-Hong \| Gaul, Michael D. \| Murray, William V. The Journal of Organic Chemistry, volume 81, issue 8, pages 3464-3469 (2016). 10.1021/acs.joc.6b00317 Cited by (5) \| Cite \| Source
A facile synthesis of 2-(3-alkynyl-2,3-dihydrobenzofuran-3-yl)acetate (journal article) Song, Fengbin \| Gaul, Michael D. \| Murray, William V. Tetrahedron Letters, volume 56, issue 40, pages 5413-5415 (2015). 10.1016/j.tetlet.2015.08.007 Cited by (1) \| Cite \| Source
7-(4-Alkylidenylpiperidinyl)-quinolone bacterial topoisomerase inhibitors (journal article) Grant, Eugene B. \| Foleno, Barbara D. \| Goldschmidt, Raul \| Hilliard, Jamese J. \| Lin, Shu-Chen \| Morrow, Brian \| Paget, Steven D. \| Weidner-Wells, Michele A. \| Xu, Xiaodong \| Xu, Xiaoqing \| ... \| Macielag, Mark J. Bioorganic & Medicinal Chemistry Letters, volume 24, issue 23, pages 5502-5506 (2014). 10.1016/j.bmcl.2014.10.014 Cited by (6) \| Cite \| Source
4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable stearoyl-CoA desaturase-1 (SCD1) inhibitors: Part 2. Pyridazine-based analogs (journal article) Yang, Shyh-Ming \| Tang, Yuting \| Rano, Thomas \| Lu, Huajun \| Kuo, Gee-Hong \| Gaul, Michael D. \| Li, Yaxin \| Ho, George \| Lang, Wensheng \| Conway, James G. \| ... \| Murray, William V. Bioorganic & Medicinal Chemistry Letters, volume 24, issue 5, pages 1437-1441 (2014). 10.1016/j.bmcl.2013.12.075 Cited by (5) \| Cite \| Source
Process Development for Scale-Up of a Novel 3,5-Substituted Thiazolidine-2,4-dione Compound as a Potent Inhibitor for Estrogen-Related Receptor 1 (journal article) Li, Xun \| Russell, Ronald K. \| Spink, Jan \| Ballentine, Scott \| Teleha, Christopher \| Branum, Shawn \| Wells, Kenneth \| Beauchamp, Derek \| Patch, Raymond \| Huang, Hui \| ... \| Murray, William Organic Process Research & Development, volume 18, issue 2, pages 321-330 (2014). 10.1021/op400325r Cited by (14) \| Cite \| Source
4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable Stearoyl-CoA desaturase-1 (SCD1) inhibitors. Part 1: Urea-based analogs (journal article) Yang, Shyh-Ming \| Tang, Yuting \| Zhang, Rui \| Lu, Huajun \| Kuo, Gee-Hong \| Gaul, Michael D. \| Li, Yaxin \| Ho, George \| Conway, James G. \| Liang, Yin \| ... \| Murray, William V. Bioorganic & Medicinal Chemistry Letters, volume 23, issue 24, pages 6773-6776 (2013). 10.1016/j.bmcl.2013.09.096 Cited by (5) \| Cite \| Source
An Efficient Synthesis of 3-Substituted N -Glycoside Indoles Useful as Sodium-Dependent Glucose Transporter Inhibitors (journal article) Li, Xun \| Wells, Kenneth M. \| Branum, Shawn \| Damon, Sandra \| Youells, Scott \| Beauchamp, Derek A. \| Palmer, David \| Stefanick, Stephen \| Russell, Ronald K. \| Murray, William Organic Process Research & Development, volume 16, issue 11, pages 1727-1732 (2012). 10.1021/op3001355 Cited by (9) \| Cite \| Source
ChemInform Abstract: Discovery of Novel Cobactin‐T Based Matrix Metalloproteinase Inhibitors via a Ring Closing Metathesis Strategy. (journal article) Wilson, Lawrence J. \| Wang, Bingbing \| Yang, Shyh‐Ming \| Scannevin, Robert H. \| Burke, Sharon L. \| Karnachi, Prabha \| Rhodes, Kenneth J. \| Murray, William V. ChemInform, volume 43, issue 10 (2012). 10.1002/chin.201210212 Cite \| Source
Discovery of novel Cobactin-T based matrix metalloproteinase inhibitors via a ring closing metathesis strategy (journal article) Wilson, Lawrence J. \| Wang, Bingbing \| Yang, Shyh-Ming \| Scannevin, Robert H. \| Burke, Sharon L. \| Karnachi, Prabha \| Rhodes, Kenneth J. \| Murray, William V. Bioorganic & Medicinal Chemistry Letters, volume 21, issue 21, pages 6485-6490 (2011). 10.1016/j.bmcl.2011.08.068 Cited by (10) \| Cite \| Source