Ronghui Lin

ScholarGPS® ID: 62684844951145

Affiliation

Johnson & Johnson, New Brunswick, New Jersey, United States

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Chemical Synthesis | Medicinal Chemistry | Cyclin-dependent Kinase

Metrics Summary

Publication Count

Predicted Citations

1,321

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

Add Delete
Hydroxylation of Substituted Anilides with Metallaphotocatalysis (journal article) Khatri, Buddha B. \| Chen, Lu \| Xu, Dawei \| Salter, Rhys \| Lin, Ronghui ACS Omega, volume 9, issue 18, pages 19982-19991 (2024). 10.1021/acsomega.3c10008 Cite \| Source
Nitro-Activated Nucleobase Exchange in the Synthesis of 2′-Fluoro-2′-Deoxyribonucleosides (journal article) Gong, Yong \| Zhang, Wei \| Chen, Lu \| Lin, Ronghui \| Zhou, Ronghui \| Salter, Rhys The Journal of Organic Chemistry, volume 87, issue 14, pages 9330-9342 (2022). 10.1021/acs.joc.2c01093 Cited by (1) \| Cite \| Source
Synthesis of deuterium‐labeled CCR2 antagonist JNJ‐26131300, [4‐(1 H ‐indol‐ 3‐yl)‐piperidin‐1‐yl]‐{1‐[3‐(3,4,5‐trifluoro‐phenyl)‐acryloyl]‐piperidin‐4‐yl}‐acetic acid (journal article) Lin, Ronghui \| Gong, Yong \| Salter, Rhys Journal of Labelled Compounds and Radiopharmaceuticals, volume 65, issue 5, pages 147-151 (2022). 10.1002/jlcr.3967 Cite \| Source
Synthesis of carboxy‐polyethylene glycol‐amine (CA (PEG)n ) and [1‐14 C]‐CA (PEG)n via oxa‐Michael addition of amino‐polyethylene glycols to propiolates vs to acrylates (journal article) Song, Fengbin \| Chen, Lu \| Lin, Ronghui \| Salter, Rhys Journal of Labelled Compounds and Radiopharmaceuticals, volume 63, issue 1, pages 15-24 (2020). 10.1002/jlcr.3816 Cite \| Source
Syntheses of isotope‐labeled SGLT2 inhibitor canagliflozin ( JNJ ‐28431754) (journal article) Lin, Ronghui \| Hoerr, David C. \| Weaner, Larry E. \| Salter, Rhys Journal of Labelled Compounds and Radiopharmaceuticals, volume 60, issue 13, pages 616-623 (2017). 10.1002/jlcr.3542 Cited by (1) \| Cite \| Source
Metabolism and Excretion of Canagliflozin in Mice, Rats, Dogs, and Humans (journal article) Mamidi, Rao N. V. S. \| Cuyckens, Filip \| Chen, Jie \| Scheers, Ellen \| Kalamaridis, Dennis \| Lin, Ronghui \| Silva, Jose \| Sha, Sue \| Evans, David C. \| Kelley, Michael F. \| ... \| Lim, Heng Keang Drug Metabolism and Disposition, volume 42, issue 5, pages 903-916 (2014). 10.1124/dmd.113.056440 Cited by (56) \| Cite \| Source \| Open Access
Expeditious syntheses of stable and radioactive isotope‐labeled anticonvulsant agent, JNJ‐26990990, and its metabolites (journal article) Lin, Ronghui \| Weaner, Larry E. \| Hoerr, David C. \| Salter, Rhys \| Gong, Yong Journal of Labelled Compounds and Radiopharmaceuticals, volume 56, issue 1, pages 22-26 (2013). 10.1002/jlcr.3013 Cited by (1) \| Cite \| Source
Facile synthesis of stable isotope‐labeled antibacterial agent RWJ‐416457 and its metabolite (journal article) Lin, Ronghui \| Weaner, Larry E. Journal of Labelled Compounds and Radiopharmaceuticals, volume 55, issue 8, pages 296-299 (2012). 10.1002/jlcr.2936 Cited by (1) \| Cite \| Source
Synthesis and evaluation of 2,7-diamino-thiazolo[4,5-d] pyrimidine analogues as anti-tumor epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (journal article) Lin, Ronghui \| Johnson, Sigmond G. \| Connolly, Peter J. \| Wetter, Steven K. \| Binnun, Eva \| Hughes, Terry V. \| Murray, William V. \| Pandey, Niranjan B. \| Moreno-Mazza, Sandra J. \| Adams, Mary \| ... \| Middleton, Steven A. Bioorganic & Medicinal Chemistry Letters, volume 19, issue 8, pages 2333-2337 (2009). 10.1016/j.bmcl.2009.02.067 Cited by (106) \| Cite \| Source
Rapid and efficient synthesis of stable isotope labeled [13 C4 , D4 ]‐5‐(hydroxymethyl)thiazole: versatile building block for biologically interesting compounds (journal article) Lin, Ronghui \| Salter, Rhys \| Gong, Yong Journal of Labelled Compounds and Radiopharmaceuticals, volume 52, issue 4, pages 110-113 (2009). 10.1002/jlcr.1576 Cited by (2) \| Cite \| Source
Synthesis of [2 H,13 C] and [14 C] labeled vasopressin V1a /V2 receptor antagonist RWJ‐676070 and its stable labeled N ‐des‐benzoyl metabolite (journal article) Gong, Yong \| Hoerr, David C. \| Weaner, Larry E. \| Lin, Ronghui Journal of Labelled Compounds and Radiopharmaceuticals, volume 51, issue 6, pages 268-272 (2008). 10.1002/jlcr.1515 Cited by (7) \| Cite \| Source
Design, Synthesis, and Evaluation of 3,4‐Disubstituted Pyrazole Analogues as Antitumor CDK Inhibitors. (journal article) Lin, Ronghui \| Chiu, George \| Yu, Yang \| Connolly, Peter J. \| Li, Shengjian \| Lu, Yanhua \| Adams, Mary \| Fuentes‐Pesquera, Angel R. \| Emanuel, Stuart L. \| Greenberger, Lee M. ChemInform, volume 38, issue 52 (2007). 10.1002/chin.200752120 Cite \| Source
Synthesis and evaluation of pyrazolo[3,4-b]pyridine CDK1 inhibitors as anti-tumor agents (journal article) Lin, Ronghui \| Connolly, Peter J. \| Lu, Yanhua \| Chiu, George \| Li, Shengjian \| Yu, Yang \| Huang, Shenlin \| Li, Xun \| Emanuel, Stuart L. \| Middleton, Steven A. \| ... \| Greenberger, Lee M. Bioorganic & Medicinal Chemistry Letters, volume 17, issue 15, pages 4297-4302 (2007). 10.1016/j.bmcl.2007.05.029 Cited by (134) \| Cite \| Source
Design, synthesis, and evaluation of 3,4-disubstituted pyrazole analogues as anti-tumor CDK inhibitors (journal article) Lin, Ronghui \| Chiu, George \| Yu, Yang \| Connolly, Peter J. \| Li, Shengjian \| Lu, Yanhua \| Adams, Mary \| Fuentes-Pesquera, Angel R. \| Emanuel, Stuart L. \| Greenberger, Lee M. Bioorganic & Medicinal Chemistry Letters, volume 17, issue 16, pages 4557-4561 (2007). 10.1016/j.bmcl.2007.05.092 Cited by (108) \| Cite \| Source
Synthesis of 3‐(1H‐Benzimidazol‐2‐yl)‐5‐isoquinolin‐4‐ylpyrazolo[1,2‐b]pyridine, a Potent Cyclin Dependent Kinase 1 (CDK1) Inhibitor. (journal article) Huang, Shenlin \| Lin, Ronghui \| Yu, Yang \| Lu, Yanhua \| Connolly, Peter J. \| Chiu, George \| Li, Shengjian \| Emanuel, Stuart L. \| Middleton, Steven A. ChemInform, volume 38, issue 29 (2007). 10.1002/chin.200729132 Cited by (59) \| Cite \| Source
4-Aryl-5-cyano-2-aminopyrimidines as VEGF-R2 inhibitors: Synthesis and biological evaluation (journal article) Hughes, Terry V. \| Emanuel, Stuart L. \| Beck, Amanda K. \| Wetter, Steven K. \| Connolly, Peter J. \| Karnachi, Prabha \| Reuman, Michael \| Seraj, Jabed \| Fuentes-Pesquera, Angel R. \| Gruninger, Robert H. \| ... \| Moffat, David F.C. Bioorganic & Medicinal Chemistry Letters, volume 17, issue 12, pages 3266-3270 (2007). 10.1016/j.bmcl.2007.04.021 Cited by (42) \| Cite \| Source
Synthesis of 3-(1H-benzimidazol-2-yl)-5-isoquinolin-4-ylpyrazolo[1,2-b]pyridine, a potent cyclin dependent kinase 1 (CDK1) inhibitor (journal article) Huang, Shenlin \| Lin, Ronghui \| Yu, Yang \| Lu, Yanhua \| Connolly, Peter J. \| Chiu, George \| Li, Shengjian \| Emanuel, Stuart L. \| Middleton, Steven A. Bioorganic & Medicinal Chemistry Letters, volume 17, issue 5, pages 1243-1245 (2007). 10.1016/j.bmcl.2006.12.031 Cited by (105) \| Cite \| Source
Synthesis and evaluation of N-acyl sulfonamides as potential prodrugs of cyclin-dependent kinase inhibitor JNJ-7706621 (journal article) Huang, Shenlin \| Connolly, Peter J. \| Lin, Ronghui \| Emanuel, Stuart \| Middleton, Steve A. Bioorganic & Medicinal Chemistry Letters, volume 16, issue 14, pages 3639-3641 (2006). 10.1016/j.bmcl.2006.04.071 Cited by (51) \| Cite \| Source
The In vitro and In vivo Effects of JNJ-7706621: A Dual Inhibitor of Cyclin-Dependent Kinases and Aurora Kinases (journal article) Emanuel, Stuart \| Rugg, Catherine A. \| Gruninger, Robert H. \| Lin, Ronghui \| Fuentes-Pesquera, Angel \| Connolly, Peter J. \| Wetter, Steven K. \| Hollister, Beth \| Kruger, Walter W. \| Napier, Cheryl \| ... \| Middleton, Steven A. Cancer Research, volume 65, issue 19, pages 9038-9046 (2005). 10.1158/0008-5472.CAN-05-0882 Cited by (103) \| Cite \| Source \| Open Access
1-Acyl-1 H -[1,2,4]triazole-3,5-diamine Analogues as Novel and Potent Anticancer Cyclin-Dependent Kinase Inhibitors: Synthesis and Evaluation of Biological Activities (journal article) Lin, Ronghui \| Connolly, Peter J. \| Huang, Shenlin \| Wetter, Steven K. \| Lu, Yanhua \| Murray, William V. \| Emanuel, Stuart L. \| Gruninger, Robert H. \| Fuentes-Pesquera, Angel R. \| Rugg, Catherine A. \| ... \| Jolliffe, Linda K. Journal of Medicinal Chemistry, volume 48, issue 13, pages 4208-4211 (2005). 10.1021/jm050267e Cited by (110) \| Cite \| Source