Yue-Mei Zhang

ScholarGPS® ID: 62307732985354

Affiliation

Johnson & Johnson, New Brunswick, New Jersey, United States

Affiliation History

Field

Pharmacy and Pharmaceutical Sciences

Discipline

Pharmacology and Toxicology

Top Specialties

Medicinal Chemistry | Matrix Metallopeptidase

Metrics Summary

Publication Count

Predicted Citations

402

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Application of Middle-Down Approach in Quantitation and Catabolite Identification of Protein by LC–high-Resolution Mass Spectrometry (journal article) Kang, Lijuan \| Xu, Shengsheng \| Pang, Yongle \| Kirchner, Tom \| Zhang, Yue-mei \| Edwards, Wilson \| Camacho, Raul \| Norquay, Lisa \| Weng, Naidong \| Jian, Wenying Bioanalysis, volume 13, issue 6, pages 465-479 (2021). 10.4155/bio-2020-0315 Cited by (1) \| Cite \| Source
Discovery of PEGylated 6-Benzhydryl-4-amino-quinazolines as Peripherally Restricted CB1 R Inverse Agonists (journal article) Zhang, Yue-Mei \| Greco, Michael \| Le Blanc, Tonya \| Lang, Wensheng \| Kauffman, Jack \| Masucci, John \| Murray, William V. \| Demarest, Keith \| Macielag, Mark Joseph ACS Medicinal Chemistry Letters, volume 11, issue 12, pages 2504-2509 (2020). 10.1021/acsmedchemlett.0c00495 Cite \| Source
Targeting Enteropeptidase with Reversible Covalent Inhibitors To Achieve Metabolic Benefits (journal article) Sun, Weimei \| Zhang, Xuqing \| Cummings, Maxwell D. \| Albarazanji, Kamal \| Wu, Jiejun \| Wang, Mina \| Alexander, Richard \| Zhu, Bin \| Zhang, YueMei \| Leonard, James \| ... \| Lenhard, James Journal of Pharmacology and Experimental Therapeutics, volume 375, issue 3, pages 510-521 (2020). 10.1124/jpet.120.000219 Cited by (14) \| Cite \| Source
The discovery of azetidine-piperazine di-amides as potent, selective and reversible monoacylglycerol lipase (MAGL) inhibitors (journal article) Zhu, Bin \| Connolly, Peter J. \| Zhang, Yue-Mei \| McDonnell, Mark E. \| Bian, Haiyan \| Lin, Shu-Chen \| Liu, Li \| Zhang, Sui-Po \| Chevalier, Kristen M. \| Brandt, Michael R. \| ... \| Macielag, Mark J. Bioorganic & Medicinal Chemistry Letters, volume 30, issue 14, pages 127243- (2020). 10.1016/j.bmcl.2020.127243 Cited by (12) \| Cite \| Source
6-Benzhydryl-4-amino-quinolin-2-ones as Potent Cannabinoid Type 1 (CB1 ) Receptor Inverse Agonists and Chemical Modifications for Peripheral Selectivity (journal article) Zhang, Yue-Mei \| Greco, Michael N. \| Macielag, Mark J. \| Teleha, Christopher A. \| DesJarlais, Renee L. \| Tang, Yuting \| Ho, George \| Hou, Cuifen \| Chen, Cailin \| Zhao, Shuyuan \| ... \| Leonard, James Journal of Medicinal Chemistry, volume 61, issue 22, pages 10276-10298 (2018). 10.1021/acs.jmedchem.8b01467 Cited by (13) \| Cite \| Source
Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation (journal article) Scannevin, Robert H. \| Alexander, Richard \| Haarlander, Tara Mezzasalma \| Burke, Sharon L. \| Singer, Monica \| Huo, Cuifen \| Zhang, Yue-Mei \| Maguire, Diane \| Spurlino, John \| Deckman, Ingrid \| ... \| Rhodes, Kenneth J. Journal of Biological Chemistry, volume 292, issue 43, pages 17963-17974 (2017). 10.1074/jbc.M117.806075 Cited by (93) \| Cite \| Source \| Open Access
1-Hydroxy-2-pyridinone-based MMP inhibitors: Synthesis and biological evaluation for the treatment of ischemic stroke (journal article) Zhang, Yue-Mei \| Fan, Xiaodong \| Chakaravarty, Devraj \| Xiang, Bangping \| Scannevin, Robert H. \| Huang, Zhihong \| Ma, Jianya \| Burke, Sharon L. \| Karnachi, Prabha \| Rhodes, Kenneth J. \| Jackson, Paul F. Bioorganic & Medicinal Chemistry Letters, volume 18, issue 1, pages 409-413 (2008). 10.1016/j.bmcl.2007.10.045 Cited by (34) \| Cite \| Source
Syntheses and in vitro evaluation of arylsulfone-based MMP inhibitors with heterocycle-derived zinc-binding groups (ZBGs) (journal article) Zhang, Yue-Mei \| Fan, Xiaodong \| Yang, Shyh-Ming \| Scannevin, Robert H. \| Burke, Sharon L. \| Rhodes, Kenneth J. \| Jackson, Paul F. Bioorganic & Medicinal Chemistry Letters, volume 18, issue 1, pages 405-408 (2008). 10.1016/j.bmcl.2007.10.049 Cited by (40) \| Cite \| Source
Inhibitors of unactivated p38 MAP kinase (journal article) Bullington, James \| Argentieri, Dennis \| Averill, Kristin \| Carter, Demetrius \| Cavender, Druie \| Fahmy, Bohumila \| Fan, Xiaodong \| Hall, Daniel \| Heintzelman, Geoffrey \| Jackson, Paul \| ... \| Zhang, Yue-Mei Bioorganic & Medicinal Chemistry Letters, volume 16, issue 23, pages 6102-6106 (2006). 10.1016/j.bmcl.2006.08.101 Cited by (11) \| Cite \| Source
Synthesis and SAR of α‐Sulfonylcarboxylic Acids as Potent Matrix Metalloproteinase Inhibitors. (journal article) Zhang, Yue‐Mei \| Fan, Xiaodong \| Xiang, Bangping \| Chakravarty, Devraj \| Scannevin, Robert \| Burke, Sharon \| Karnachi, Prabha \| Rhodes, Kenneth \| Jackson, Paul ChemInform, volume 37, issue 37 (2006). 10.1002/chin.200637084 Cite \| Source
Synthesis and SAR of α-sulfonylcarboxylic acids as potent matrix metalloproteinase inhibitors (journal article) Zhang, Yue-Mei \| Fan, Xiaodong \| Xiang, Bangping \| Chakravarty, Devraj \| Scannevin, Robert \| Burke, Sharon \| Karnachi, Prabha \| Rhodes, Kenneth \| Jackson, Paul Bioorganic & Medicinal Chemistry Letters, volume 16, issue 12, pages 3096-3100 (2006). 10.1016/j.bmcl.2006.03.065 Cited by (12) \| Cite \| Source
Synthesis of Pyrimido[4,5‐b]indoles and Benzo[4,5]furo[2,3‐d]pyrimidines via Palladium‐Catalyzed Intramolecular Arylation. (journal article) Zhang, Yue‐Mei \| Razler, Thomas \| Jackson, Paul F. ChemInform, volume 34, issue 5 (2003). 10.1002/chin.200305171 Cite \| Source
Synthesis of pyrimido[4,5-b]indoles and benzo[4,5]furo[2,3-d]pyrimidines via palladium-catalyzed intramolecular arylation (journal article) Zhang, Yue-Mei \| Razler, Thomas \| Jackson, Paul F. Tetrahedron Letters, volume 43, issue 46, pages 8235-8239 (2002). 10.1016/S0040-4039(02)02036-1 Cited by (43) \| Cite \| Source