William R. Markesbery

ScholarGPS® ID: 62189590730704

Affiliation
Columbia University, New York City, United States
Affiliation History

Field
Medicine
Discipline
Pathology
Top Specialties
Alzheimer's Disease | Neuropathology | Dementia | Cognitive Deficit | Mild Cognitive Impairment | Oxidative Stress | Trace Element | Lipid | Neuron | Peptide | Lipid Peroxidation | Neoplasm | Proteomics | RNA | Antioxidant
Metrics Summary
Publication Count
500
Predicted Citations
75,681
Predicted h-index
141
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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APOε2 and education in cognitively normal older subjects with high levels of AD pathology at autopsy: findings from the Nun Study (journal article)
Iacono, Diego | Zandi, Peter | Gross, Myron | Markesbery, William R. | Pletnikova, Olga | Rudow, Gay | Troncoso, Juan C.
Oncotarget, volume 6, issue 16, pages 14082-14091 (2015).
10.18632/oncotarget.4118
Cited by (11) | Cite | Source | Open Access
Oxidative lipid modification of nicastrin enhances amyloidogenic γ‐secretase activity in Alzheimer’s disease (journal article)
Gwon, A‐Ryeong | Park, Jong‐Sung | Arumugam, Thiruma V. | Kwon, Yong‐Kook | Chan, Sic L. | Kim, Seol‐Hee | Baik, Sang‐Ha | Yang, Sunghee | Yun, Young‐Kwang | Choi, Yuri | ... | Jo, Dong‐Gyu
Aging Cell, volume 11, issue 4, pages 559-568 (2012).
10.1111/j.1474-9726.2012.00817.x
Cited by (78) | Cite | Source | Open Access
Elevated 4-hydroxyhexenal in Alzheimer's disease (AD) progression (journal article)
Bradley, Melissa A. | Xiong-Fister, Shuling | Markesbery, William R. | Lovell, Mark A.
Neurobiology of Aging, volume 33, issue 6, pages 1034-1044 (2012).
10.1016/j.neurobiolaging.2010.08.016
Cited by (75) | Cite | Source | Open Access
Understanding Dementia Prevalence Among Centenarians (journal article)
Poon, L. W. | Woodard, J. L. | Stephen Miller, L. | Green, R. | Gearing, M. | Davey, A. | Arnold, J. | Martin, P. | Siegler, I. C. | Nahapetyan, L. | ... | Markesbery, W.
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, volume 67A, issue 4, pages 358-365 (2012).
10.1093/gerona/glr250
Cited by (53) | Cite | Source | Open Access
Increased 5S rRNA Oxidation in Alzheimer's Disease (journal article)
Ding, Qunxing | Zhu, Haiyan | Zhang, Bing | Soriano, Augusto | Burns, Roxanne | Markesbery, William R.
Journal of Alzheimer's Disease, volume 29, issue 1, pages 201-209 (2012).
10.3233/JAD-2012-111058
Cited by (18) | Cite | Source
Molecular changes in brain aging and Alzheimer's disease are mirrored in experimentally silenced cortical neuron networks (journal article)
Gleichmann, Marc | Zhang, Yongqing | Wood, William H. | Becker, Kevin G. | Mughal, Mohamed R. | Pazin, Michael J. | van Praag, Henriette | Kobilo, Tali | Zonderman, Alan B. | Troncoso, Juan C. | ... | Mattson, Mark P.
Neurobiology of Aging, volume 33, issue 1, pages 205.e1-205.e18 (2012).
10.1016/j.neurobiolaging.2010.08.012
Cited by (40) | Cite | Source | Open Access
Alzheimer disease pathology in cognitively healthy elderly: A genome-wide study (journal article)
Kramer, Patricia L. | Xu, Haiyan | Woltjer, Randall L. | Westaway, Shawn K. | Clark, David | Erten-Lyons, Deniz | Kaye, Jeffrey A. | Welsh-Bohmer, Kathleen A. | Troncoso, Juan C. | Markesbery, William R. | ... | Ott, Jurg
Neurobiology of Aging, volume 32, issue 12, pages 2113-2122 (2011).
10.1016/j.neurobiolaging.2010.01.010
Cited by (86) | Cite | Source | Open Access
Proteomic analysis of brain proteins in APP/PS‐1 human double mutant knock‐in mice with increasing amyloid β‐peptide deposition: Insights into the effects of in vivo treatment with N ‐acetylcysteine as a potential therapeutic intervention in mild cognitiv (journal article)
Robinson, Renã A. S. | Joshi, Gururaj | Huang, Quanzhen | Sultana, Rukhsana | Baker, Austin S. | Cai, Jian | Pierce, William | St. Clair, Daret K. | Markesbery, William R. | Butterfield, D. Allan
PROTEOMICS, volume 11, issue 21, pages 4243-4256 (2011).
10.1002/pmic.201000523
Cited by (37) | Cite | Source | Open Access
Proteomic identification of specifically carbonylated brain proteins in APPNLh/APPNLh×PS-1P264L/PS-1P264L human double mutant knock-in mice model of Alzheimer disease as a function of age (journal article)
Sultana, Rukhsana | Robinson, Renã A.S. | Di Domenico, Fabio | Abdul, Hafiz Mohmmad | Clair, Daret K.St. | Markesbery, William R. | Cai, Jian | Pierce, William M. | Butterfield, D. Allan
Journal of Proteomics, volume 74, issue 11, pages 2430-2440 (2011).
10.1016/j.jprot.2011.06.015
Cited by (35) | Cite | Source | Open Access
Redox Proteomics Analysis of Brains from Subjects with Amnestic Mild Cognitive Impairment Compared to Brains from Subjects with Preclinical Alzheimer's Disease: Insights into Memory Loss in MCI (journal article)
Aluise, Christopher D. | Robinson, Renã A.S. | Cai, Jian | Pierce, William M. | Markesbery, William R. | Butterfield, D. Allan
Journal of Alzheimer's Disease, volume 23, issue 2, pages 257-269 (2011).
10.3233/jad-2010-101083
Cited by (84) | Cite | Source
Neuron Specific Toxicity of Oligomeric Amyloid-β: Role for JUN-Kinase and Oxidative Stress (journal article)
Ebenezer, Philip J. | Weidner, Adam M. | LeVine, Harry | Markesbery, William R. | Murphy, M. Paul | Zhang, Le | Dasuri, Kalavathi | Fernandez-Kim, Sun Ok | Bruce-Keller, Annadora J. | Gavilán, Elena | Keller, Jeffrey N.
Journal of Alzheimer's Disease, volume 22, issue 3, pages 839-848 (2010).
10.3233/JAD-2010-101161
Cited by (46) | Cite | Source | Open Access
Association between male gender and cortical Lewy body pathology in large autopsy series (journal article)
Nelson, Peter T. | Schmitt, Frederick A. | Jicha, Gregory A. | Kryscio, Richard J. | Abner, Erin L. | Smith, Charles D. | Van Eldik, Linda J. | Markesbery, William R.
Journal of Neurology, volume 257, issue 11, pages 1875-1881 (2010).
10.1007/s00415-010-5630-4
Cited by (72) | Cite | Source | Open Access
Prodromal clinical manifestations of neuropathologically confirmed Lewy body disease (journal article)
Jicha, G.A. | Schmitt, F.A. | Abner, E. | Nelson, P.T. | Cooper, G.E. | Smith, C.D. | Markesbery, W.R.
Neurobiology of Aging, volume 31, issue 10, pages 1805-1813 (2010).
10.1016/j.neurobiolaging.2008.09.017
Cited by (88) | Cite | Source | Open Access
Potential in vivo amelioration by N‐acetyl‐L‐cysteine of oxidative stress in brain in human double mutant APP/PS‐1 knock‐in mice: Toward therapeutic modulation of mild cognitive impairment (journal article)
Huang, Quanzhen | Aluise, Christopher D. | Joshi, Gururaj | Sultana, Rukhsana | St. Clair, Daret K. | Markesbery, William R. | Butterfield, D. Allan
Journal of Neuroscience Research, volume 88, issue 12, pages 2618-2629 (2010).
10.1002/jnr.22422
Cited by (73) | Cite | Source
Preclinical Alzheimer disease: Brain oxidative stress, Aβ peptide and proteomics (journal article)
Aluise, Christopher D. | Robinson, Renã A. Sowell | Beckett, Tina L. | Murphy, M. Paul | Cai, Jian | Pierce, William M. | Markesbery, William R. | Butterfield, D. Allan
Neurobiology of Disease, volume 39, issue 2, pages 221-228 (2010).
10.1016/j.nbd.2010.04.011
Cited by (70) | Cite | Source | Open Access
O2‐05‐05: Factors associated with cognitive impairment in persons with autopsy Braak stage 4 or greater: Results from the Honolulu‐Asia Aging Study (HAAS) (journal article)
White, Lon | Petrovitch, Helen | Ross, Webster | Masaki, Kamal | Uyehara-Lock, Jane | Gelber, Rebecca | Markesbery, William | Launer, Lenore
Alzheimer's & Dementia, volume 6, issue 4S_Part_4 (2010).
10.1016/j.jalz.2010.05.334
Cite | Source
Increased levels of 4-hydroxynonenal and acrolein in the brain in preclinical Alzheimer disease (journal article)
Bradley, M.A. | Markesbery, W.R. | Lovell, M.A.
Free Radical Biology and Medicine, volume 48, issue 12, pages 1570-1576 (2010).
10.1016/j.freeradbiomed.2010.02.016
Cited by (165) | Cite | Source | Open Access
NOX Activity Is Increased in Mild Cognitive Impairment (journal article)
Bruce-Keller, Annadora J. | Gupta, Sunita | Parrino, Taryn E. | Knight, Alecia G. | Ebenezer, Philip J. | Weidner, Adam M. | LeVine, Harry | Keller, Jeffrey N. | Markesbery, William R.
Antioxidants & Redox Signaling, volume 12, issue 12, pages 1371-1382 (2010).
10.1089/ars.2009.2823
Cited by (84) | Cite | Source | Open Access
Evidence that γ-secretase mediates oxidative stress-induced β-secretase expression in Alzheimer's disease (journal article)
Jo, Dong-Gyu | Arumugam, Thiruma V. | Woo, Ha-Na | Park, Jong-Sung | Tang, Sung-Chun | Mughal, Mohamed | Hyun, Dong-Hoon | Park, Jun-Hyung | Choi, Yun-Hyung | Gwon, A-Ryeong | ... | Mattson, Mark P.
Neurobiology of Aging, volume 31, issue 6, pages 917-925 (2010).
10.1016/j.neurobiolaging.2008.07.003
Cited by (80) | Cite | Source | Open Access
Increased protein hydrophobicity in response to aging and Alzheimer disease (journal article)
Dasuri, Kalavathi | Ebenezer, Philip | Zhang, Le | Fernandez-Kim, Sun Ok | Bruce-Keller, Annadora J. | Markesbery, William R. | Keller, Jeffrey N.
Free Radical Biology and Medicine, volume 48, issue 10, pages 1330-1337 (2010).
10.1016/j.freeradbiomed.2010.02.012
Cited by (16) | Cite | Source | Open Access