Sandro Goruppi

ScholarGPS® ID: 62050114227458

Affiliation

Harvard University, Cambridge, United States

Affiliation History

Field

Life Sciences

Discipline

Biology and Biological Sciences

Top Specialties

Cancer | Autophagy | Cell Death | Receptor Tyrosine Kinase

Metrics Summary

Publication Count

Predicted Citations

2,395

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Androgen receptor is a determinant of melanoma targeted drug resistance (journal article) Samarkina, Anastasia \| Youssef, Markus Kirolos \| Ostano, Paola \| Ghosh, Soumitra \| Ma, Min \| Tassone, Beatrice \| Proust, Tatiana \| Chiorino, Giovanna \| Levesque, Mitchell P. \| Goruppi, Sandro \| Dotto, Gian Paolo Nature Communications, volume 14, issue 1 (2023). 10.1038/s41467-023-42239-w Cited by (8) \| Cite \| Source
The ULK3 kinase is a determinant of keratinocyte self-renewal and tumorigenesis targeting the arginine methylome (journal article) Goruppi, Sandro \| Clocchiatti, Andrea \| Bottoni, Giulia \| Di Cicco, Emery \| Ma, Min \| Tassone, Beatrice \| Neel, Victor \| Demehri, Shadhmer \| Simon, Christian \| Paolo Dotto, G. Nature Communications, volume 14, issue 1 (2023). 10.1038/s41467-023-36410-6 Cited by (4) \| Cite \| Source
NOTCH1 gene amplification promotes expansion of Cancer Associated Fibroblast populations in human skin (journal article) Katarkar, Atul \| Bottoni, Giulia \| Clocchiatti, Andrea \| Goruppi, Sandro \| Bordignon, Pino \| Lazzaroni, Francesca \| Gregnanin, Ilaria \| Ostano, Paola \| Neel, Victor \| Dotto, G. Paolo Nature Communications, volume 11, issue 1 (2020). 10.1038/s41467-020-18919-2 Cited by (24) \| Cite \| Source
CSL controls telomere maintenance and genome stability in human dermal fibroblasts (journal article) Bottoni, Giulia \| Katarkar, Atul \| Tassone, Beatrice \| Ghosh, Soumitra \| Clocchiatti, Andrea \| Goruppi, Sandro \| Bordignon, Pino \| Jafari, Paris \| Tordini, Fabio \| Lunardi, Thomas \| ... \| Paolo Dotto, G. Nature Communications, volume 10, issue 1 (2019). 10.1038/s41467-019-11785-7 Cited by (13) \| Cite \| Source
A role for stromal autophagy in cancer-associated fibroblast activation (journal article) Goruppi, Sandro \| Clocchiatti, Andrea \| Dotto, G. Paolo Autophagy (2019). 10.1080/15548627.2019.1569936 Cited by (17) \| Cite \| Source
Androgen receptor functions as transcriptional repressor of cancer-associated fibroblast activation (journal article) Clocchiatti, Andrea \| Ghosh, Soumitra \| Procopio, Maria-Giuseppina \| Mazzeo, Luigi \| Bordignon, Pino \| Ostano, Paola \| Goruppi, Sandro \| Bottoni, Giulia \| Katarkar, Atul \| Levesque, Mitchell \| ... \| Dotto, G. Paolo Journal of Clinical Investigation, volume 128, issue 12, pages 5531-5548 (2018). 10.1172/JCI99159 Cited by (40) \| Cite \| Source
Autophagy Controls CSL/RBPJκ Stability through a p62/SQSTM1-Dependent Mechanism (journal article) Goruppi, Sandro \| Jo, Seung-Hee \| Laszlo, Csaba \| Clocchiatti, Andrea \| Neel, Victor \| Dotto, G. Paolo Cell Reports, volume 24, issue 12, pages 3108-3114.e4 (2018). 10.1016/j.celrep.2018.08.043 Cited by (19) \| Cite \| Source \| Open Access
The ULK3 Kinase Is Critical for Convergent Control of Cancer-Associated Fibroblast Activation by CSL and GLI (journal article) Goruppi, Sandro \| Procopio, Maria-Giuseppina \| Jo, Seunghee \| Clocchiatti, Andrea \| Neel, Victor \| Dotto, G. Paolo Cell Reports, volume 20, issue 10, pages 2468-2479 (2017). 10.1016/j.celrep.2017.08.048 Cited by (33) \| Cite \| Source \| Open Access
Convergent roles of ATF3 and CSL in chromatin control of cancer-associated fibroblast activation (journal article) Kim, Dong Eun \| Procopio, Maria-Giuseppina \| Ghosh, Soumitra \| Jo, Seung-Hee \| Goruppi, Sandro \| Magliozzi, Francesco \| Bordignon, Pino \| Neel, Victor \| Angelino, Paolo \| Dotto, G. Paolo Journal of Experimental Medicine, volume 214, issue 8, pages 2349-2368 (2017). 10.1084/jem.20170724 Cited by (30) \| Cite \| Source \| Open Access
Recapitulating the pancreatic cancer microenvironment in a three-dimensional heterocellular culture model to innovate photodynamic therapy (journal article) Broekgaarden, M. \| Anbil, S. \| Bulin, A.-L. \| Goruppi, S. \| Dotto, G.P. \| Rizvi, I. \| Hasan, T. Photodiagnosis and Photodynamic Therapy, volume 17 (2017). 10.1016/j.pdpdt.2017.01.066 Cite \| Source
Erratum: Corrigendum: Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation (journal article) Procopio, Maria-Giuseppina \| Laszlo, Csaba \| Al Labban, Dania \| Kim, Dong Eun \| Bordignon, Pino \| Jo, Seung-Hee \| Goruppi, Sandro \| Menietti, Elena \| Ostano, Paola \| Ala, Ugo \| ... \| Dotto, G. Paolo Nature Cell Biology, volume 17, issue 10, pages 1370-1370 (2015). 10.1038/ncb3242 Cited by (6) \| Cite \| Source \| Open Access
Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation (journal article) Procopio, Maria-Giuseppina \| Laszlo, Csaba \| Al Labban, Dania \| Kim, Dong Eun \| Bordignon, Pino \| Jo, Seung-Hee \| Goruppi, Sandro \| Menietti, Elena \| Ostano, Paola \| Ala, Ugo \| ... \| Dotto, G. Paolo Nature Cell Biology, volume 17, issue 9, pages 1193-1204 (2015). 10.1038/ncb3228 Cited by (170) \| Cite \| Source \| Open Access
Mesenchymal stroma: primary determinant and therapeutic target for epithelial cancer (journal article) Goruppi, Sandro \| Dotto, G. Paolo Trends in Cell Biology, volume 23, issue 12, pages 593-602 (2013). 10.1016/j.tcb.2013.08.006 Cited by (41) \| Cite \| Source \| Open Access
NUPR1 works against the metabolic stress-induced autophagy-associated cell death in pancreatic cancer cells (journal article) Hamidi, Tewfik \| Cano, Carla E. \| Grasso, Daniel \| Garcia, Maria Noé \| Sandi, Maria José \| Calvo, Ezequiel L. \| Dagorn, Jean-Charles \| Lomberk, Gwen \| Goruppi, Sandro \| Urrutia, Raul \| ... \| Iovanna, Juan L. Autophagy, volume 9, issue 1, pages 95-97 (2013). 10.4161/auto.22258 Cited by (23) \| Cite \| Source \| Open Access
Nupr1-Aurora Kinase A Pathway Provides Protection against Metabolic Stress-Mediated Autophagic-Associated Cell Death (journal article) Hamidi, Tewfik \| Cano, Carla E. \| Grasso, Daniel \| Garcia, Maria Noé \| Sandi, Maria José \| Calvo, Ezequiel L. \| Dagorn, Jean-Charles \| Lomberk, Gwen \| Urrutia, Raul \| Goruppi, Sandro \| ... \| Iovanna, Juan L. Clinical Cancer Research, volume 18, issue 19, pages 5234-5246 (2012). 10.1158/1078-0432.CCR-12-0026 Cited by (63) \| Cite \| Source \| Open Access
Decreased metalloprotease 9 induction, cardiac fibrosis, and higher autophagy after pressure overload in mice lacking the transcriptional regulator p8 (journal article) Georgescu, Serban P. \| Aronovitz, Mark J. \| Iovanna, Juan L. \| Patten, Richard D. \| Kyriakis, John M. \| Goruppi, Sandro American Journal of Physiology-Cell Physiology, volume 301, issue 5, pages C1046-C1056 (2011). 10.1152/ajpcell.00211.2011 Cited by (29) \| Cite \| Source \| Open Access
Deficiency of transcriptional regulator p8 induces autophagy and causes impaired cardiac function (journal article) Kong, Derek K. \| Georgescu, Serban P. \| Kyriakis, John M. \| Goruppi, Sandro Autophagy, volume 6, issue 5, pages 652-654 (2010). 10.4161/auto.6.5.12067 Cited by (4) \| Cite \| Source \| Open Access
Deficiency of the Transcriptional Regulator p8 Results in Increased Autophagy and Apoptosis, and Causes Impaired Heart Function (journal article) Kong, Derek K. \| Georgescu, Serban P. \| Cano, Carla \| Aronovitz, Mark J. \| Iovanna, Juan Lucio \| Patten, Richard D. \| Kyriakis, John M. \| Goruppi, Sandro Molecular Biology of the Cell, volume 21, issue 8, pages 1335-1349 (2010). 10.1091/mbc.e09-09-0818 Cited by (52) \| Cite \| Source \| Open Access
Stress-inducible Protein p8 Is Involved in Several Physiological and Pathological Processes (journal article) Goruppi, Sandro \| Iovanna, Juan Lucio Journal of Biological Chemistry, volume 285, issue 3, pages 1577-1581 (2010). 10.1074/jbc.R109.080887 Cited by (85) \| Cite \| Source \| Open Access
Mice Deficient for the Stress-Induced Transcriptional Regulator p8 Have a Decreased Metalloprotease 9 Induction and Cardiac Fibrosis after Transverse Aortic Constriction (journal article) Goruppi, Sandro \| Georgescu, Serban \| Iovanna, Juan \| Aronowitz, Mark \| Patten, Richard \| Kyriakis, John Journal of Cardiac Failure, volume 15, issue 6, pages S39-S40 (2009). 10.1016/j.cardfail.2009.06.294 Cite \| Source