Thomas J. Greshock

ScholarGPS® ID: 61657456555403

Affiliation

Merck & Co., Inc., United States

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

2,629

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

Add Delete
Structural insights into selective small molecule activation of PKG1α (conference) Metwally, Essam \| Mak, Victor \| Soriano, Aileen \| Zebisch, Matthias \| Silvestre, H Leonardo \| McEwan, Paul A \| Ermakov, Grigori \| Baumont, Maribel \| Tawa, Paul \| Barker, John J \| ... \| Fischmann, Thierry cGMP: Generators, Effectors and Therapeutic Implications (2024) 10.14293/CGMP.24000013.v1 Cite \| Source
Microscale Purification with Direct Charged Aerosol Detector Quantitation Using Selective Online One- or Two-Dimensional Liquid Chromatography (journal article) Hettiarachchi, Kanaka \| Streckfuss, Eric \| Sanzone, Jillian R. \| Wang, Jun \| Hayes, Michael \| Kong, May \| Greshock, Thomas J. Analytical Chemistry, volume 94, issue 23, pages 8309-8316 (2022). 10.1021/acs.analchem.2c00750 Cited by (10) \| Cite \| Source
Ultra-fast microscale purification of chiral racemates and achiral pharmaceuticals with analytical supercritical fluid chromatography (journal article) Hayes, Michael \| Hettiarachchi, Kanaka \| Lang, Simon \| Wang, Jun \| Greshock, Thomas J. Journal of Chromatography A, volume 1665 (2022). 10.1016/j.chroma.2022.462829 Cited by (8) \| Cite \| Source
Discovery of Arylsulfonamide Nav 1.7 Inhibitors: IVIVC, MPO Methods, and Optimization of Selectivity Profile (journal article) Roecker, Anthony J. \| Layton, Mark E. \| Pero, Joseph E. \| Kelly, Michael J. \| Greshock, Thomas J. \| Kraus, Richard L. \| Li, Yuxing \| Klein, Rebecca \| Clements, Michelle \| Daley, Christopher \| ... \| Burgey, Christopher S. ACS Medicinal Chemistry Letters, volume 12, issue 6, pages 1038-1049 (2021). 10.1021/acsmedchemlett.1c00218 Cited by (8) \| Cite \| Source
Nav 1.7 target modulation and efficacy can be measured in nonhuman primate assays (journal article) Kraus, Richard L. \| Zhao, Fuqiang \| Pall, Parul S. \| Zhou, Dan \| Vardigan, Joshua D. \| Danziger, Andrew \| Li, Yuxing \| Daley, Christopher \| Ballard, Jeanine E. \| Clements, Michelle K. \| ... \| Houghton, Andrea K. Science Translational Medicine, volume 13, issue 594 (2021). 10.1126/scitranslmed.aay1050 Cited by (11) \| Cite \| Source
Discovery of a new class of integrin antibodies for fibrosis (journal article) Zhang, Ji \| Wang, Tao \| Saigal, Ashmita \| Johnson, Josephine \| Morrisson, Jennifer \| Tabrizifard, Sahba \| Hollingsworth, Scott A. \| Eddins, Michael J. \| Mao, Wenxian \| O’Neill, Kim \| ... \| Handa, Masahisa Scientific Reports, volume 11, issue 1 (2021). 10.1038/s41598-021-81253-0 Cited by (12) \| Cite \| Source
Substituted bicyclic heteroaryl allosteric modulators of nicotinic acetylcholine receptors (patent) Crowley, Brendan M. \| Bell, Ian M. \| Harvey, Andrew John \| Shipe, William D. \| Leavitt, Kenneth J. \| Sanders, John M. \| Guiadeen, Deodial G. \| Suen, Linda M. \| Greshock, Thomas J. \| Rada, Vanessa L. Patent Number: 10870630 (2020) Cited by (1) \| Cite \| Source
Diamino-alkylamino-linked arylsulfonamide compounds with selective activity in voltage-gated sodium channels (patent) Greshock, Thomas J. \| Mulhearn, James \| Guo, Liangqin \| Zhang, Ting \| Wang, Deping \| Kim, Ronald M. \| Layton, Mark E. \| Kelly, III, Michael J. \| Anand, Rajan \| Nantermet, Philippe \| ... \| Zhou, Gang Patent Number: 10519147 (2019) Cite \| Source
Subminute micro-isolation of pharmaceuticals with ultra-high pressure liquid chromatography (journal article) Hettiarachchi, Kanaka \| Hayes, Michael \| Desai, Aditya J. \| Wang, Jun \| Ren, Zhao \| Greshock, Thomas J. Journal of Pharmaceutical and Biomedical Analysis, volume 176 (2019). 10.1016/j.jpba.2019.112794 Cited by (11) \| Cite \| Source
N1-phenylpropane-1,2-diamine compounds with selective activity in voltage-gated sodium channels (patent) Roecker, Anthony J. \| Layton, Mark E. \| Greshock, Thomas J. \| Pero, Joseph E. \| Kelly, III, Michael J. \| Zhang, Ting Patent Number: 10442778 (2019) Cite \| Source
Hydroxyalkylamine- and hydroxycycloalkylamine-substituted diamine-arylsulfonamide compounds with selective activity in voltage-gated sodium channels (patent) Greshock, Thomas J. \| Mulhearn, James \| Zheng, Junying \| Kim, Ronald M. \| Zhang, Ting \| Roecker, Anthony J. \| Won, Walter \| Nantermet, Philippe \| Anand, Rajan \| Zhou, Gang \| ... \| Guo, Liangqin Patent Number: 10221167 (2019) Cite \| Source
Pyrrolo[2,3-C]pyridines as imaging agents for neurofibrilary tangles (patent) Walji, Abbas M. \| Hostetler, Eric \| Greshock, Thomas J. \| Li, Jing \| Moore, Keith P. \| Bennacef, Idriss \| Mulhearn, James \| Selnick, Harold \| Wang, Yaode \| Yang, Kun \| Fu, Jianmin Patent Number: 10022461 (2018) Cite \| Source
MK-7622: A First-in-Class M1 Positive Allosteric Modulator Development Candidate (journal article) Beshore, Douglas C. \| N. Di Marco, Christina \| Chang, Ronald K. \| Greshock, Thomas J. \| Ma, Lei \| Wittmann, Marion \| Seager, Matthew A. \| Koeplinger, Kenneth A. \| Thompson, Charles D. \| Fuerst, Joy \| ... \| Kuduk, Scott D. ACS Medicinal Chemistry Letters, volume 9, issue 7, pages 652-656 (2018). 10.1021/acsmedchemlett.8b00095 Cited by (25) \| Cite \| Source
HIV protease inhibitors (patent) McCauley, John A. \| Bennett, David Jonathan \| Bungard, Christopher J. \| Greshock, Thomas J. \| Holloway, M. Katharine \| Williams, Peter D. \| Beaulieu, Christian \| Crane, Sheldon \| Lessard, Stephanie \| Mckay, Daniel \| ... \| Tummanapalli, Satyanarayana Patent Number: 9994587 (2018) Cite \| Source
Allosteric modulators of nicotinic acetylcholine receptors (patent) Crowley, Brendan M. \| Campbell, Brian T. \| Duffy, Joseph L. \| Greshock, Thomas J. \| Guiadeen, Deodial G. \| Harvey, Andrew John \| Huff, Belinda C. \| Leavitt, Kenneth J. \| Rada, Vanessa L. \| Sanders, John M. \| ... \| Bell, Ian M. Patent Number: 9840481 (2017) Cited by (1) \| Cite \| Source
HIV protease inhibitors (patent) McCauley, John A. \| Beaulieu, Christian \| Bennett, David Jonathan \| Bungard, Christopher J. \| Crane, Sheldon \| Greshock, Thomas J. \| Holloway, Katharine M. \| McKay, Daniel \| Molinaro, Carmela \| Moradei, Oscar Miguel \| ... \| Williams, Peter D. Patent Number: 9834526 (2017) Cite \| Source
Pyrrolo[2,3-C]pyridines as imaging agents for neurofibrillary (patent) Walji, Abbas W. \| Hostetler, Eric \| Greshock, Thomas J. \| Li, Jing \| Moore, Keith P. \| Bennacef, Idriss \| Mulhearn, James \| Selnick, Harold \| Wang, Yaode \| Yang, Kun \| Fu, Jianmin Patent Number: 9808542 (2017) Cite \| Source
Compounds inhibiting leucine-rich repeat kinase enzyme activity (patent) DeMong, Duane \| Miller, Michael \| Liu, Hong \| Dai, Xing \| Greshock, Thomas \| Stamford, Andrew \| Nargund, Ravi Patent Number: 9809568 (2017) Cite \| Source
HIV protease inhibitors (patent) McCauley, John A. \| Beaulieu, Christian \| Bennett, David Jonathan \| Bungard, Christopher J. \| Crane, Sheldon \| Greshock, Thomas J. \| Holloway, Katharine M. \| Juteau, Helen \| McKay, Daniel \| Molinaro, Carmela \| ... \| Williams, Peter D. Patent Number: 9737545 (2017) Cite \| Source
Compounds inhibiting leucine-rich repeat kinase enzyme activity (patent) DeMong, Duane \| Greshock, Thomas J. \| Chang, Ronald K. \| Dai, Xing \| Liu, Hong \| McCauley, John A. \| Li, Wei \| Basu, Kallol \| Scott, Jack D. \| Miller, Michael Patent Number: 9718818 (2017) Cited by (5) \| Cite \| Source