Gregory C. Leo

ScholarGPS® ID: 61452170796692

Affiliation
Johnson & Johnson, New Brunswick, New Jersey, United States
Affiliation History

Field
Physical Sciences and Mathematics
Discipline
Chemistry
Top Specialties
Medicinal Chemistry | Spectroscopy | Chemical Synthesis | Metabolism | Conformational Isomerism
Metrics Summary
Publication Count
47
Predicted Citations
1,555
Predicted h-index
21
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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Prebiotic Colloidal Oat Supports the Growth of Cutaneous Commensal Bacteria Including S. epidermidis and Enhances the Production of Lactic Acid (journal article)
Liu-Walsh, Fang | Tierney, Neena K | Hauschild, James | Rush, Allison K | Masucci, John | Leo, Gregory C | Capone, Kimberly A
Clinical, Cosmetic and Investigational Dermatology, volume Volume 14 (2021).
10.2147/CCID.S253386
Cited by (8) | Cite | Source
Time course metabolome of Roux-en-Y gastric bypass confirms correlation between leptin, body weight and the microbiome (journal article)
Seridi, Loqmane | Leo, Gregory C. | Dohm, G. Lynis | Pories, Walter J. | Lenhard, James
PLOS ONE, volume 13, issue 5, pages e0198156- (2018).
10.1371/journal.pone.0198156
Cited by (16) | Cite | Source | Open Access
Metabolic and Hormonal Alterations Induced by Roux-en-Y Gastric Bypass (journal article)
Seridi, Loqmane | Leo, Gregory C. | Lynis, Dohm | Pories, Walter J. | Lenhard, James
bioRxiv (2017).
10.1101/230201
Cite | Source | Open Access
Can Untargeted Metabolomics Be Utilized in Drug Discovery/Development? (journal article)
Caldwell, Gary W. | Leo, Gregory C.
Current Topics in Medicinal Chemistry, volume 17, issue 24 (2017).
10.2174/1568026617666170707130032
Cited by (16) | Cite | Source
Microbiota‐Derived Metabolites Associated with Metabolic Improvements after Gastric Bypass Surgery and their Effects on Intestinal Cells in vitro (journal article)
Jennis, Matthew | Mabus, John R | Cavanaugh, Cassandre R. | Leo, Gregory | Lenhard, James | Hornby, Pamela J
The FASEB Journal, volume 30, issue S1 (2016).
10.1096/fasebj.30.1_supplement.720.3
Cite | Source
Lab-Scale Preparation of a Novel Cyclopenta[b]furan Chemokine Receptor Antagonist (journal article)
Teleha, Christopher A. | Branum, Shawn | Zhang, Yongzheng | Reuman, Michael E. | Van Der Steen, Luc | Verbeek, Marc | Fawzy, Nagy | Leo, Gregory C. | Winters, Michael P. | Kang, Fu-An | ... | Vanbaelen, Hilde
Organic Process Research & Development, volume 18, issue 12, pages 1630-1640 (2014).
10.1021/op500266w
Cited by (8) | Cite | Source
A thiocarbamate inhibitor of endothelial lipase raises HDL cholesterol levels in mice (journal article)
Greco, M.N. | Connelly, M.A. | Leo, G.C. | Olson, M.W. | Powell, E. | Huang, Z. | Hawkins, M. | Smith, C. | Schalk-Hihi, C. | Darrow, A.L. | ... | Hlasta, D.J.
Bioorganic & Medicinal Chemistry Letters, volume 23, issue 9, pages 2595-2597 (2013).
10.1016/j.bmcl.2013.02.113
Cited by (8) | Cite | Source
Automatic Analysis of Quantitative NMR Data of Pharmaceutical Compound Libraries (journal article)
Liu, Xuejun | Kolpak, Michael X. | Wu, Jiejun | Leo, Gregory C.
Analytical Chemistry, volume 84, issue 15, pages 6914-6918 (2012).
10.1021/ac301544u
Cited by (16) | Cite | Source
NMR‐based metabolomics of urine for the atherosclerotic mouse model using apolipoprotein‐E deficient mice (journal article)
Leo, Gregory C. | Darrow, Andrew L.
Magnetic Resonance in Chemistry, volume 47, issue S1 (2009).
10.1002/mrc.2470
Cited by (21) | Cite | Source | Open Access
Suzuki−Miyaura Approach to JNJ-26076713, an Orally Active Tetrahydroquinoline-Containing αV β3 /αV β5 Integrin Antagonist. Enantioselective Synthesis and Stereochemical Studies (journal article)
Kinney, William A. | Teleha, Christopher A. | Thompson, Andrew S. | Newport, Maria | Hansen, Ryan | Ballentine, Scott | Ghosh, Shyamali | Mahan, Andrew | Grasa, Gabriela | Zanotti-Gerosa, Antonio | ... | Maryanoff, Bruce E.
The Journal of Organic Chemistry, volume 73, issue 6, pages 2302-2310 (2008).
10.1021/jo702551t
Cited by (25) | Cite | Source
Collagen-Related Peptides: Self-Assembly of Short, Single Strands into a Functional Biomaterial of Micrometer Scale (journal article)
Cejas, Mabel A. | Kinney, William A. | Chen, Cailin | Leo, Gregory C. | Tounge, Brett A. | Vinter, Jeremy G. | Joshi, Pratik P. | Maryanoff, Bruce E.
Journal of the American Chemical Society, volume 129, issue 8, pages 2202-2203 (2007).
10.1021/ja066986f
Cited by (129) | Cite | Source
Biotransformation of Geldanamycin and 17-Allylamino-17-Demethoxygeldanamycin by Human Liver Microsomes: Reductive versus Oxidative Metabolism and Implications (journal article)
Lang, W. | Caldwell, G. W. | Li, J. | Leo, G. C. | Jones, W. J. | Masucci, J. A.
Drug Metabolism and Disposition, volume 35, issue 1, pages 21-29 (2007).
10.1124/dmd.106.009639
Cited by (24) | Cite | Source | Open Access
Facile Dephosphonylation of β-Ketophosphonic Acids:  Mechanistic Studies (journal article)
Hawkins, Michael J. | Powell, Eugene T. | Leo, Gregory C. | Gauthier, Diane A. | Greco, Michael N. | Maryanoff, Bruce
Organic Letters, volume 8, issue 16, pages 3429-3431 (2006).
10.1021/ol060519l
Cited by (8) | Cite | Source
N -GLUCURONIDATION OF THE PLATELET-DERIVED GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITOR 6,7-(DIMETHOXY-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-3-YL)-(3-FLUORO-PHENYL)-AMINE BY HUMAN UDP-GLUCURONOSYLTRANSFERASES (journal article)
Yan, Z. | Caldwell, G. W. | Gauthier, D. | Leo, G. C. | Mei, J. | Ho, C. Y. | Jones, W. J. | Masucci, J. A. | Tuman, R. W. | Galemmo, R. A. | Johnson, D. L.
Drug Metabolism and Disposition, volume 34, issue 5, pages 748-755 (2006).
10.1124/dmd.106.009274
Cited by (28) | Cite | Source | Open Access
Distribution and metabolism of the antipsychotic agent mazapertine succinate in rats (journal article)
Caldwell, Gary W. | Wu, Wu-Nan | McKown, Linda A. | Diane Gauthier, A. | Masucci, John A. | Jones, William J. | Leo, Gregory C. | Reitz, Allen B.
Journal of Pharmaceutical and Biomedical Analysis, volume 41, issue 2, pages 500-509 (2006).
10.1016/j.jpba.2005.10.052
Cited by (1) | Cite | Source
(6,7-Dimethoxy-2,4-dihydroindeno[1,2- c ]pyrazol-3-yl)phenylamines: Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitors with Broad Antiproliferative Activity against Tumor Cells (journal article)
Ho, Chih Y. | Ludovici, Donald W. | Maharoof, Umar S. M. | Mei, Jay | Sechler, Jan L. | Tuman, Robert W. | Strobel, Eric D. | Andraka, Laura | Yen, Hwa-Kwo | Leo, Gregory | ... | Galemmo, Robert A.
Journal of Medicinal Chemistry, volume 48, issue 26, pages 8163-8173 (2005).
10.1021/jm050680m
Cited by (34) | Cite | Source
Metabolism and excretion of the antiepileptic/antimigraine drug, topiramate in animals and humans (journal article)
Caldwell, G. W. | Wu, W. N. | Masucci, J. A. | Mckown, L. A. | Gauthier, D. | Jones, W. J. | Leo, G. C. | Maryanoff, B. E.
European Journal of Drug Metabolism and Pharmacokinetics, volume 30, issue 3, pages 151-164 (2005).
10.1007/BF03190614
Cited by (30) | Cite | Source
Synthesis of Macrocycles via Cobalt‐Mediated [2 + 2 + 2] Cycloadditions (journal article)
Bonaga, Llorente V. R. | Zhang, Han‐Cheng | Moretto, Alessandro F. | Ye, Hong | Gauthier, Diane A. | Li, Jian | Leo, Gregory C. | Maryanoff, Bruce E.
ChemInform, volume 36, issue 32 (2005).
10.1002/chin.200532150
Cited by (1) | Cite | Source
The application of nuclear magnetic resonance-based metabonomics to the dominant–submissive rat behavioral model (journal article)
Leo, Gregory C. | Caldwell, Gary W. | Crooke, Jeffrey | Malatynska, Ewa | Cotto, Carlos | Hastings, Becki | Scowcroft, Jaclyn | Hall, Jeffrey | Browne, Karina | Hageman, William
Analytical Biochemistry, volume 339, issue 1, pages 174-178 (2005).
10.1016/j.ab.2005.01.029
Cited by (18) | Cite | Source
Synthesis of Macrocycles via Cobalt-Mediated [2 + 2 + 2] Cycloadditions (journal article)
Boñaga, Llorente V. R. | Zhang, Han-Cheng | Moretto, Alessandro F. | Ye, Hong | Gauthier, Diane A. | Li, Jian | Leo, Gregory C. | Maryanoff, Bruce E.
Journal of the American Chemical Society, volume 127, issue 10, pages 3473-3485 (2005).
10.1021/ja045001w
Cited by (155) | Cite | Source