Nazli Azimi

ScholarGPS® ID: 61288451650179

Affiliation

University of Maryland, College Park, United States

Affiliation History

Field

Medicine

Discipline

Immunology

Top Specialties

Virus | Cytokine | HIV/AIDS | Immunodeficiency

Metrics Summary

Publication Count

Predicted Citations

2,278

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Effective treatment with the selective cytokine inhibitor BNZ-1 reveals the cytokine dependency of T-LGL leukemia (journal article) Brammer, Jonathan E. \| Ballen, Karen \| Sokol, Lubomir \| Querfeld, Christiane \| Nakamura, Ryotaro \| Mishra, Anjali \| McLaughlin, Eric M. \| Feith, David \| Azimi, Nazli \| Waldmann, Thomas A. \| ... \| Loughran, Thomas Blood, volume 142, issue 15, pages 1271-1280 (2023). 10.1182/blood.2022017643 Cited by (3) \| Cite \| Source
Co-Inhibition of IL-2, IL-9 and IL-15 By the Novel Immunomodulator, Bnz-1, Provides Clinical Efficacy in Patients with Refractory Cutaneous T Cell Lymphoma in a Phase 1/2 Clinical Trial (journal article) Querfeld, Christiane \| William, Basem M. \| Sokol, Lubomir \| Akilov, Oleg \| Poligone, Brian \| Zain, Jasmine \| Tagaya, Yutaka \| Azimi, Nazli Blood, volume 136, issue Supplement 1, pages 37-37 (2020). 10.1182/blood-2020-143135 Cited by (2) \| Cite \| Source
Results From a First‐in‐Human Study of BNZ‐1, a Selective Multicytokine Inhibitor Targeting Members of the Common Gamma (γc) Family of Cytokines (journal article) Frohna, Paul A. \| Ratnayake, Anoshie \| Doerr, Nick \| Basheer, Asjad \| Al‐Mawsawi, Laith Q. \| Kim, Woo Jae \| Zapata, Juan C. \| Wu, Xiaorong \| Waldmann, Thomas A. \| Azimi, Nazli \| Tagaya, Yutaka The Journal of Clinical Pharmacology, volume 60, issue 2, pages 264-273 (2020). 10.1002/jcph.1522 Cited by (16) \| Cite \| Source
Identification of a γc Receptor Antagonist That Prevents Reprogramming of Human Tissue-resident Cytotoxic T Cells by IL15 and IL21 (journal article) Ciszewski, Cezary \| Discepolo, Valentina \| Pacis, Alain \| Doerr, Nick \| Tastet, Olivier \| Mayassi, Toufic \| Maglio, Mariantonia \| Basheer, Asjad \| Al-Mawsawi, Laith Q. \| Green, Peter H.R. \| ... \| Jabri, Bana Gastroenterology, volume 158, issue 3, pages 625-637.e13 (2020). 10.1053/j.gastro.2019.10.006 Cited by (27) \| Cite \| Source
Bnz-1, a Selective γ-Chain Cytokine Inhibitor Has Clinical Activity in Patients with Cutaneous T Cell Lymphoma By Selectively Blocking IL-2, IL-15 and IL-9 Signaling: Results of a Multicenter, Open-Label Phase 1 Trial (journal article) Querfeld, Christiane \| William, Basem M. \| Brammer, Jonathan E. \| Sokol, Lubomir \| Tagaya, Yutaka \| Frohna, Paul \| Azimi, Nazli \| Zain, Jasmine M. Blood, volume 134, issue Supplement_1, pages 1557-1557 (2019). 10.1182/blood-2019-129201 Cite \| Source
Blockade of IL-15 Utilizing Bnz-1, a Selective γ-Chain Inhibiting Peptide, Is Safe and Has Clinical Activity in Patients with T-Cell Large Granular Lymphocytic Leukemia (T-LGLL): Results of a Phase I/II Multi-Center Clinical Trial (journal article) Brammer, Jonathan E. \| Sokol, Lubomir \| Tagaya, Yutaka \| Rogers, Kerry \| Mishra, Anjali \| Waldmann, Thomas A. \| Azimi, Nazli \| Frohna, Paul \| Ratnayake, Anoshie \| Loughran, Thomas P \| Ballen, Karen Blood, volume 134, issue Supplement_1, pages 2835-2835 (2019). 10.1182/blood-2019-129291 Cited by (9) \| Cite \| Source
IL-2 and IL-15 blockade by BNZ-1, an inhibitor of selective γ-chain cytokines, decreases leukemic T-cell viability (journal article) Wang, T. Tiffany \| Yang, Jun \| Zhang, Yong \| Zhang, Meili \| Dubois, Sigrid \| Conlon, Kevin C. \| Tagaya, Yutaka \| Hamele, Cait E. \| Dighe, Shubha \| Olson, Thomas L. \| ... \| Loughran, Thomas P. Leukemia, volume 33, issue 5, pages 1243-1255 (2019). 10.1038/s41375-018-0290-y Cited by (40) \| Cite \| Source
LB1517 Clinical effects of BNZ-1, a selective inhibitor of IL-2/IL-9/IL15 in development for alopecia areata (journal article) Frohna, P. \| Tagaya, Y. \| Ratnayake, A. \| Waldmann, T. \| Azimi, N. Journal of Investigative Dermatology, volume 138, issue 9, pages B9- (2018). 10.1016/j.jid.2018.06.048 Cite \| Source
B-101 Shooting many cytokines with a single Stone-a novel anti-cytokine technology with broad clinical application (journal article) Tagaya, Yutaka \| Zapata, Juan \| Wu, Xiaorong \| Basheer, Asjad \| Frohna, Paul \| Azimi, Nazli JAIDS Journal of Acquired Immune Deficiency Syndromes, volume 77, issue 1, pages 35-35 (2018). 10.1097/01.qai.0000532491.48546.5d Cite \| Source
P-A2 Shooting many cytokines by a single stone (journal article) Wu, Xiaorong \| Jabri, Bana \| Nazli, Azimi \| Tagaya, Yutaka JAIDS Journal of Acquired Immune Deficiency Syndromes, volume 74 (2017). 10.1097/01.qai.0000513885.24292.30 Cite \| Source
P-B27 Targeting the binding interface on a shared receptor subunit of a cytokine family enables the inhibition of multiple member-cytokines with selectable target spectrum (journal article) Nata, Toshie \| Basheer, Asjad \| Van Besien, Rick \| Cocchi, Fiorenza \| Azimi, Nazli \| Tagaya, Yutaka JAIDS Journal of Acquired Immune Deficiency Syndromes, volume 71, issue Supplement 1, pages 85- (2016). 10.1097/01.qai.0000479599.81710.68 Cite \| Source \| Open Access
A multi-cytokine inhibitory peptide (BNZ 132-1) that is a potential therapeutic agent for HAMTSP and other necrotizing diseases. (journal article) Nata, Toshie \| Zapata, Juan Carlos \| Massoud, Raya \| Jacobson, Steve \| Azimi, Nazli \| Tagaya, Yutaka Retrovirology, volume 12, issue S1 (2015). 10.1186/1742-4690-12-S1-O22 Cited by (2) \| Cite \| Source \| Open Access
Targeting the Binding Interface on a Shared Receptor Subunit of a Cytokine Family Enables the Inhibition of Multiple Member Cytokines with Selectable Target Spectrum (journal article) Nata, Toshie \| Basheer, Asjad \| Cocchi, Fiorenza \| van Besien, Richard \| Massoud, Raya \| Jacobson, Steven \| Azimi, Nazli \| Tagaya, Yutaka Journal of Biological Chemistry, volume 290, issue 37, pages 22338-22351 (2015). 10.1074/jbc.M115.661074 Cited by (20) \| Cite \| Source \| Open Access
Common γ-chain blocking peptide reduces in vitro immune activation markers in HTLV-1-associated myelopathy/tropical spastic paraparesis (journal article) Massoud, Raya \| Enose-Akahata, Yoshimi \| Tagaya, Yutaka \| Azimi, Nazli \| Basheer, Asjad \| Jacobson, Steven Proceedings of the National Academy of Sciences, volume 112, issue 35, pages 11030-11035 (2015). 10.1073/pnas.1412626112 Cited by (14) \| Cite \| Source \| Open Access
Common γ-chain blocking peptide reduces in vitro immune activation markers in HTLV-1 associated myelopathy/ tropical spastic paraparesis. (P6.299) (journal article) Massoud, Raya \| Akahata, Yoshimi \| Tagaya, Yutaka \| Azimi, Nazli \| Basheer, Asjad \| Jacobson, Steven Neurology, volume 84, issue 14_supplement (2015). 10.1212/WNL.84.14_supplement.P6.299 Cite \| Source
BNZ-gamma peptide, a potential therapeutic agent in HTLV-1 associated myelopathy (journal article) Massoud, Raya \| Enose-Akahata, Yoshimi \| Tagaya, Yutaka \| Azimi, Nazli \| Jacobson, Steven Retrovirology, volume 11, issue S1 (2014). 10.1186/1742-4690-11-S1-P14 Cited by (1) \| Cite \| Source \| Open Access
P168 Selective inhibition of multiple cytokines: A novel therapeutic strategy for immune-mediated diseases (journal article) Azimi, N. \| Massoud, R. \| Jacobson, S. \| Tagaya, Y. Cytokine, volume 59, issue 3, pages 573- (2012). 10.1016/j.cyto.2012.06.269 Cited by (1) \| Cite \| Source
Repression of IRF-4 target genes in human T cell leukemia virus-1 infection (journal article) Mamane, Yaël \| Grandvaux, Nathalie \| Hernandez, Eduardo \| Sharma, Sonia \| Innocente, Steve A \| Lee, Jonathan M \| Azimi, Nazli \| Lin, Rongtuan \| Hiscott, John Oncogene, volume 21, issue 44, pages 6751-6765 (2002). 10.1038/sj.onc.1205843 Cited by (31) \| Cite \| Source \| Open Access
Regulation of IFN Regulatory Factor 4 Expression in Human T Cell Leukemia Virus-I-Transformed T Cells (journal article) Sharma, Sonia \| Grandvaux, Nathalie \| Mamane, Yael \| Genin, Pierre \| Azimi, Nazli \| Waldmann, Thomas \| Hiscott, John The Journal of Immunology, volume 169, issue 6, pages 3120-3130 (2002). 10.4049/jimmunol.169.6.3120 Cited by (50) \| Cite \| Source \| Open Access
Viral Activation of Interleukin-15 (IL-15): Characterization of a Virus-Inducible Element in the IL-15 Promoter Region (journal article) Azimi, Nazli \| Shiramizu, Kevin M. \| Tagaya, Yutaka \| Mariner, Jennifer \| Waldmann, Thomas A. Journal of Virology, volume 76, issue 13, pages 6864-6864 (2002). 10.1128/JVI.76.13.6864.2002 Cited by (40) \| Cite \| Source \| Open Access