June Zhi Xu

ScholarGPS® ID: 60606970274820

Affiliation

Johnson & Johnson, New Brunswick, New Jersey, United States

Affiliation History

Field

Medicine

Discipline

Cardiology

Top Specialties

Medicinal Chemistry

Metrics Summary

Publication Count

Predicted Citations

438

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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GRK Inhibition Potentiates Glucagon-Like Peptide-1 Action (journal article) Lee, Seunghun P. \| Qi, Jenson \| Xu, Guozhang \| Rankin, Matthew M. \| Littrell, James \| Xu, June Zhi \| Bakaj, Ivona \| Pocai, Alessandro Frontiers in Endocrinology, volume 12 (2021). 10.3389/fendo.2021.652628 Cited by (3) \| Cite \| Source
Hit-to-lead optimization and discovery of a potent, and orally bioavailable G protein coupled receptor kinase 2 (GRK2) inhibitor (journal article) Xu, Guozhang \| Gaul, Michael D. \| Liu, Zhijie \| DesJarlais, Renee L. \| Qi, Jenson \| Wang, Weixue \| Krosky, Daniel \| Petrounia, Ioanna \| Milligan, Cynthia M. \| Hermans, An \| ... \| Spurlino, John C. Bioorganic & Medicinal Chemistry Letters, volume 30, issue 23, pages 127602- (2020). 10.1016/j.bmcl.2020.127602 Cited by (4) \| Cite \| Source
5,5-Difluoro- and 5-Fluoro-5-methyl-hexose-based C-Glucosides as potent and orally bioavailable SGLT1 and SGLT2 dual inhibitors (journal article) Xu, Guozhang \| Du, Fuyong \| Kuo, Gee-Hong \| Xu, June Zhi \| Liang, Yin \| Demarest, Keith \| Gaul, Michael D. Bioorganic & Medicinal Chemistry Letters, volume 30, issue 17, pages 127387- (2020). 10.1016/j.bmcl.2020.127387 Cited by (8) \| Cite \| Source
Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors (journal article) Xu, Guozhang \| Gaul, Michael D. \| Kuo, Gee-Hong \| Du, Fuyong \| Xu, June Zhi \| Wallace, Nathaniel \| Hinke, Simon \| Kirchner, Thomas \| Silva, Jose \| Huebert, Norman D. \| ... \| Demarest, Keith Bioorganic & Medicinal Chemistry Letters, volume 28, issue 21, pages 3446-3453 (2018). 10.1016/j.bmcl.2018.09.025 Cited by (9) \| Cite \| Source
Synthesis and biological evaluation of benzocyclobutane-C-glycosides as potent and orally active SGLT1/SGLT2 dual inhibitors (journal article) Kuo, Gee-Hong \| Gaul, Micheal D. \| Liang, Yin \| Xu, June Z. \| Du, Fuyong \| Hornby, Pamela \| Xu, Guozhang \| Qi, Jenson \| Wallace, Nathaniel \| Lee, Seunghun \| ... \| Demarest, Keith Bioorganic & Medicinal Chemistry Letters, volume 28, issue 7, pages 1182-1187 (2018). 10.1016/j.bmcl.2018.02.057 Cited by (29) \| Cite \| Source
Discovery of a novel potent GPR40 full agonist (journal article) Meegalla, Sanath K. \| Huang, Hui \| Martin, Tonya \| Xu, June \| Zhao, Shuyuan \| Liu, Jianying \| Hall, Meghan \| Gunnet, Joe \| Wang, Yuanping \| Rady, Brian \| ... \| Player, Mark R. Bioorganic & Medicinal Chemistry Letters, volume 28, issue 4, pages 720-726 (2018). 10.1016/j.bmcl.2018.01.013 Cited by (8) \| Cite \| Source
Effect of Canagliflozin on Renal Threshold for Glucose, Glycemia, and Body Weight in Normal and Diabetic Animal Models (journal article) Liang, Yin \| Arakawa, Kenji \| Ueta, Kiichiro \| Matsushita, Yasuaki \| Kuriyama, Chiaki \| Martin, Tonya \| Du, Fuyong \| Liu, Yi \| Xu, June \| Conway, Bruce \| ... \| Demarest, Keith PLoS ONE, volume 7, issue 2, pages e30555- (2012). 10.1371/journal.pone.0030555 Cited by (201) \| Cite \| Source \| Open Access
Synthesis and structure–activity relationships of thiadiazole-derivatives as potent and orally active peroxisome proliferator-activated receptors α/δ dual agonists (journal article) Shen, Lan \| Zhang, Yan \| Wang, Aihua \| Sieber-McMaster, Ellen \| Chen, Xiaoli \| Pelton, Patricia \| Xu, June Z. \| Yang, Maria \| Zhu, Peifang \| Zhou, Lubing Bioorganic & Medicinal Chemistry, volume 16, issue 6, pages 3321-3341 (2008). 10.1016/j.bmc.2007.12.005 Cited by (26) \| Cite \| Source
Design and synthesis of indane-ureido-thioisobutyric acids: A novel class of PPARα agonists (journal article) Matthews, Jay M. \| Chen, Xiaoli \| Cryan, Ellen \| Hlasta, Dennis J. \| Rybczynski, Philip J. \| Strauss, Kim \| Tang, Yuting \| Xu, June Z. \| Yang, Maria \| Zhou, Lubing \| Demarest, Keith T. Bioorganic & Medicinal Chemistry Letters, volume 17, issue 24, pages 6773-6778 (2007). 10.1016/j.bmcl.2007.10.041 Cited by (20) \| Cite \| Source