Joy Drobnick

ScholarGPS® ID: 60036685909144

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Medicinal Chemistry

Metrics Summary

Publication Count

Predicted Citations

493

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Discovery of Potent Benzolactam IRAK4 Inhibitors with Robust in Vivo Activity (journal article) Rajapaksa, Naomi S. \| Gobbi, Alberto \| Drobnick, Joy \| Do, Steven \| Kolesnikov, Aleksandr \| Liang, Jun \| Chen, Yongsheng \| Sujatha-Bhaskar, Swathi \| Huang, Zhiyu \| Brightbill, Hans \| ... \| Bryan, Marian C. ACS Medicinal Chemistry Letters, volume 11, issue 3, pages 327-333 (2020). 10.1021/acsmedchemlett.9b00380 Cited by (17) \| Cite \| Source
Naphthyridines as inhibitors of HPK1 (patent) Chan, Bryan \| Rajapaksa, Naomi \| Siu, Michael \| Stivala, Craig \| Tellis, John \| Wang, Weiru \| Wei, BinQing \| Zhou, Aihe \| Cartwright, Matthew W. \| Gancia, Emanuela \| ... \| Mendonca, Rohan Patent Number: 10407424 (2019) Cite \| Source
Development of Potent and Selective Pyrazolopyrimidine IRAK4 Inhibitors (journal article) Bryan, Marian C. \| Drobnick, Joy \| Gobbi, Alberto \| Kolesnikov, Aleksandr \| Chen, Yongsheng \| Rajapaksa, Naomi \| Ndubaku, Chudi \| Feng, Jianwen \| Chang, Willy \| Francis, Ross \| ... \| Kiefer, James R. Journal of Medicinal Chemistry, volume 62, issue 13, pages 6223-6240 (2019). 10.1021/acs.jmedchem.9b00439 Cited by (19) \| Cite \| Source
Discovery of Small-Molecule Inhibitors of Ubiquitin Specific Protease 7 (USP7) Using Integrated NMR and in Silico Techniques (journal article) Di Lello, Paola \| Pastor, Richard \| Murray, Jeremy M. \| Blake, Robert A. \| Cohen, Frederick \| Crawford, Terry D. \| Drobnick, Joy \| Drummond, Jason \| Kategaya, Lorna \| Kleinheinz, Tracy \| ... \| Tsui, Vickie Journal of Medicinal Chemistry, volume 60, issue 24, pages 10056-10070 (2017). 10.1021/acs.jmedchem.7b01293 Cited by (59) \| Cite \| Source
1,7-diazacarbazoles and methods of use (patent) Dyke, Hazel Joan \| Gazzard, Lewis \| Williams, Karen \| Chen, Huifen \| Kintz, Samuel \| Drobnick, Joy \| Lyssikatos, Joseph P. \| Goodacre, Simon \| Macleod, Calum \| Ellwood, Charles Patent Number: 9440976 (2016) Cite \| Source
Chemically Diverse Group I p21-Activated Kinase (PAK) Inhibitors Impart Acute Cardiovascular Toxicity with a Narrow Therapeutic Window (journal article) Rudolph, Joachim \| Murray, Lesley J. \| Ndubaku, Chudi O. \| O’Brien, Thomas \| Blackwood, Elizabeth \| Wang, Weiru \| Aliagas, Ignacio \| Gazzard, Lewis \| Crawford, James J. \| Drobnick, Joy \| ... \| Zhong, Yu Journal of Medicinal Chemistry, volume 59, issue 11, pages 5520-5541 (2016). 10.1021/acs.jmedchem.6b00638 Cited by (52) \| Cite \| Source
Discovery of Clinical Development Candidate GDC-0084, a Brain Penetrant Inhibitor of PI3K and mTOR (journal article) Heffron, Timothy P. \| Ndubaku, Chudi O. \| Salphati, Laurent \| Alicke, Bruno \| Cheong, Jonathan \| Drobnick, Joy \| Edgar, Kyle \| Gould, Stephen E. \| Lee, Leslie B. \| Lesnick, John D. \| ... \| Olivero, Alan G. ACS Medicinal Chemistry Letters, volume 7, issue 4, pages 351-356 (2016). 10.1021/acsmedchemlett.6b00005 Cited by (77) \| Cite \| Source \| Open Access
Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-p Ka Polar Moiety (journal article) Ndubaku, Chudi O. \| Crawford, James J. \| Drobnick, Joy \| Aliagas, Ignacio \| Campbell, David \| Dong, Ping \| Dornan, Laura M. \| Duron, Sergio \| Epler, Jennifer \| Gazzard, Lewis \| ... \| Rudolph, Joachim ACS Medicinal Chemistry Letters, volume 6, issue 12, pages 1241-1246 (2015). 10.1021/acsmedchemlett.5b00398 Cited by (58) \| Cite \| Source \| Open Access
Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal Angiogenesis (journal article) Ndubaku, Chudi O. \| Crawford, Terry D. \| Chen, Huifen \| Boggs, Jason W. \| Drobnick, Joy \| Harris, Seth F. \| Jesudason, Rajiv \| McNamara, Erin \| Nonomiya, Jim \| Sambrone, Amy \| ... \| Ye, Weilan ACS Medicinal Chemistry Letters, volume 6, issue 8, pages 913-918 (2015). 10.1021/acsmedchemlett.5b00174 Cited by (34) \| Cite \| Source \| Open Access
Discovery of the 1,7-diazacarbazole class of inhibitors of checkpoint kinase 1 (journal article) Gazzard, Lewis \| Appleton, Brent \| Chapman, Kerry \| Chen, Huifen \| Clark, Kevin \| Drobnick, Joy \| Goodacre, Simon \| Halladay, Jason \| Lyssikatos, Joseph \| Schmidt, Stephen \| ... \| Malek, Shiva Bioorganic & Medicinal Chemistry Letters, volume 24, issue 24, pages 5704-5709 (2014). 10.1016/j.bmcl.2014.10.063 Cited by (17) \| Cite \| Source
ChemInform Abstract: A Chemoselective Reformatsky—Negishi Approach to α‐Haloaryl Esters. (journal article) Wong, Brian \| Linghu, Xin \| Crawford, James J. \| Drobnick, Joy \| Lee, Wendy \| Zhang, Haiming ChemInform, volume 45, issue 29 (2014). 10.1002/chin.201429099 Cite \| Source
A chemoselective Reformatsky–Negishi approach to α-haloaryl esters (journal article) Wong, Brian \| Linghu, Xin \| Crawford, James J. \| Drobnick, Joy \| Lee, Wendy \| Zhang, Haiming Tetrahedron, volume 70, issue 7, pages 1508-1515 (2014). 10.1016/j.tet.2013.12.053 Cited by (29) \| Cite \| Source