Marta Giorgis

ScholarGPS® ID: 59394109430722

Affiliation

University of Turin, Turin, Italy

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Medicinal Chemistry | Scaffolding | Antioxidant | Inflammasome

Metrics Summary

Publication Count

Predicted Citations

1,552

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAFV600E Protein (journal article) Marini, Elisabetta \| Marino, Marco \| Gionfriddo, Giulia \| Maione, Federica \| Pandini, Marta \| Oddo, Daniele \| Giorgis, Marta \| Rolando, Barbara \| Blua, Federica \| Gastaldi, Simone \| ... \| Bertinaria, Massimo Molecules, volume 27, issue 23, pages 8513- (2022). 10.3390/molecules27238513 Cited by (5) \| Cite \| Source
Identification of Human Dihydroorotate Dehydrogenase Inhibitor by a Pharmacophore-Based Virtual Screening Study (journal article) Galati, Salvatore \| Sainas, Stefano \| Giorgis, Marta \| Boschi, Donatella \| Lolli, Marco L. \| Ortore, Gabriella \| Poli, Giulio \| Tuccinardi, Tiziano Molecules, volume 27, issue 12, pages 3660- (2022). 10.3390/molecules27123660 Cited by (6) \| Cite \| Source
Multitarget Antioxidant NO-Donor Organic Nitrates: A Novel Approach to Overcome Nitrates Tolerance, an Ex Vivo Study (journal article) Marini, Elisabetta \| Giorgis, Marta \| Leporati, Marta \| Rolando, Barbara \| Chegaev, Konstantin \| Lazzarato, Loretta \| Bertinaria, Massimo \| Vincenti, Marco \| Di Stilo, Antonella Antioxidants, volume 11, issue 1, pages 166- (2022). 10.3390/antiox11010166 Cited by (4) \| Cite \| Source
Chemical Modulation of the 1-(Piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazole-2-one Scaffold as a Novel NLRP3 Inhibitor (journal article) Gastaldi, Simone \| Boscaro, Valentina \| Gianquinto, Eleonora \| Sandall, Christina F. \| Giorgis, Marta \| Marini, Elisabetta \| Blua, Federica \| Gallicchio, Margherita \| Spyrakis, Francesca \| MacDonald, Justin A. \| Bertinaria, Massimo Molecules, volume 26, issue 13, pages 3975- (2021). 10.3390/molecules26133975 Cited by (13) \| Cite \| Source
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5- a ]pyridine Scaffold: SAR of the Biphenyl Moiety (journal article) Sainas, Stefano \| Giorgis, Marta \| Circosta, Paola \| Gaidano, Valentina \| Bonanni, Davide \| Pippione, Agnese C. \| Bagnati, Renzo \| Passoni, Alice \| Qiu, Yaqi \| Cojocaru, Carina Florina \| ... \| Lolli, Marco L. Journal of Medicinal Chemistry, volume 64, issue 9, pages 5404-5428 (2021). 10.1021/acs.jmedchem.0c01549 Cited by (22) \| Cite \| Source
Effective deploying of a novel DHODH inhibitor against herpes simplex type 1 and type 2 replication (journal article) Luganini, Anna \| Sibille, Giulia \| Mognetti, Barbara \| Sainas, Stefano \| Pippione, Agnese Chiara \| Giorgis, Marta \| Boschi, Donatella \| Lolli, Marco L. \| Gribaudo, Giorgio Antiviral Research, volume 189 (2021). 10.1016/j.antiviral.2021.105057 Cited by (23) \| Cite \| Source
The Synergism between DHODH Inhibitors and Dipyridamole Leads to Metabolic Lethality in Acute Myeloid Leukemia (journal article) Gaidano, Valentina \| Houshmand, Mohammad \| Vitale, Nicoletta \| Carrà, Giovanna \| Morotti, Alessandro \| Tenace, Valerio \| Rapelli, Stefania \| Sainas, Stefano \| Pippione, Agnese Chiara \| Giorgis, Marta \| ... \| Circosta, Paola Cancers, volume 13, issue 5, pages 1003- (2021). 10.3390/cancers13051003 Cited by (20) \| Cite \| Source
Meds433, a New Dihydroorotate Dehydrogenase Inhibitor, Induces Apoptosis and Differentiation in Acute Myeloid Leukemia (journal article) Gaidano, Valentina \| Circosta, Paola \| Cignetti, Alessandro \| Houshmand, Mohammad \| Vitale, Nicoletta \| Sainas, Stefano \| Pippione, Agnese \| Marraudino, Manuela \| Bonaldo, Brigitta \| Giorgis, Marta \| ... \| Saglio, Giuseppe Blood, volume 134, issue Supplement_1, pages 3942-3942 (2019). 10.1182/blood-2019-128085 Cite \| Source
Development of covalent NLRP3 inflammasome inhibitors: Chemistry and biological activity (journal article) Bertinaria, Massimo \| Gastaldi, Simone \| Marini, Elisabetta \| Giorgis, Marta Archives of Biochemistry and Biophysics, volume 670 (2019). 10.1016/j.abb.2018.11.013 Cited by (28) \| Cite \| Source
Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors: Synthesis, biological evaluation and X-ray structural studies (journal article) Pippione, Agnese C. \| Sainas, Stefano \| Goyal, Parveen \| Fritzson, Ingela \| Cassiano, Gustavo C. \| Giraudo, Alessandro \| Giorgis, Marta \| Tavella, Tatyana A. \| Bagnati, Renzo \| Rolando, Barbara \| ... \| Lolli, Marco L. European Journal of Medicinal Chemistry, volume 163 (2019). 10.1016/j.ejmech.2018.11.044 Cited by (24) \| Cite \| Source
Methotrexate-Loaded Solid Lipid Nanoparticles: Protein Functionalization to Improve Brain Biodistribution (journal article) Muntoni, Elisabetta \| Martina, Katia \| Marini, Elisabetta \| Giorgis, Marta \| Lazzarato, Loretta \| Salaroglio, Iris Chiara \| Riganti, Chiara \| Lanotte, Michele \| Battaglia, Luigi Pharmaceutics, volume 11, issue 2, pages 65- (2019). 10.3390/pharmaceutics11020065 Cited by (43) \| Cite \| Source
A Comparative Study on the Efficacy of NLRP3 Inflammasome Signaling Inhibitors in a Pre-clinical Model of Bowel Inflammation (journal article) Pellegrini, Carolina \| Fornai, Matteo \| Colucci, Rocchina \| Benvenuti, Laura \| D’Antongiovanni, Vanessa \| Natale, Gianfranco \| Fulceri, Federica \| Giorgis, Marta \| Marini, Elisabetta \| Gastaldi, Simone \| ... \| Antonioli, Luca Frontiers in Pharmacology, volume 9 (2018). 10.3389/fphar.2018.01405 Cited by (37) \| Cite \| Source
Chemical modifications of Tonda Gentile Trilobata hazelnut and derived processing products under different infrared and hot‐air roasting conditions: a combined analytical study (journal article) Binello, Arianna \| Giorgis, Marta \| Cena, Clara \| Cravotto, Giancarlo \| Rotolo, Laura \| Oliveri, Paolo \| Malegori, Cristina \| Cavallero, Maria Chiara \| Buso, Stefania \| Casale, Monica Journal of the Science of Food and Agriculture, volume 98, issue 12, pages 4561-4569 (2018). 10.1002/jsfa.8984 Cited by (5) \| Cite \| Source
Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a ]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors (journal article) Sainas, Stefano \| Pippione, Agnese C. \| Lupino, Elisa \| Giorgis, Marta \| Circosta, Paola \| Gaidano, Valentina \| Goyal, Parveen \| Bonanni, Davide \| Rolando, Barbara \| Cignetti, Alessandro \| ... \| Lolli, Marco L. Journal of Medicinal Chemistry, volume 61, issue 14, pages 6034-6055 (2018). 10.1021/acs.jmedchem.8b00373 Cited by (57) \| Cite \| Source
Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors (journal article) Sainas, Stefano \| Pippione, Agnese Chiara \| Lupino, Elisa \| Giorgis, Marta \| Circosta, Paola \| Gaidano, Valentina \| Goyal, Parveen \| bonanni, davide \| Rolando, Barbara \| Cignetti, Alessandro \| ... \| Lolli, Marco L. Journal of Medicinal Chemistry, volume 61, issue 14, pages 6034-6055 (2018). 10.2210/pdb6fmd/pdb Cited by (3) \| Cite \| Source
α-ketoglutarate dehydrogenase inhibition counteracts breast cancer-associated lung metastasis (journal article) Atlante, Sandra \| Visintin, Alessia \| Marini, Elisabetta \| Savoia, Matteo \| Dianzani, Chiara \| Giorgis, Marta \| Sürün, Duran \| Maione, Federica \| Schnütgen, Frank \| Farsetti, Antonella \| ... \| Gaetano, Carlo Cell Death & Disease, volume 9, issue 7 (2018). 10.1038/s41419-018-0802-8 Cited by (52) \| Cite \| Source \| Open Access
Use of human Dihydroorotate Dehydrogenase (hDHODH) Inhibitors in Autoimmune Diseases and New Perspectives in Cancer Therapy (journal article) Lolli, Marco L. \| Sainas, Stefano \| Pippione, Agnese C. \| Giorgis, Marta \| Boschi, Donatella \| Dosio, Franco Recent Patents on Anti-Cancer Drug Discovery, volume 13, issue 1 (2018). 10.2174/1574892812666171108124218 Cited by (60) \| Cite \| Source
Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease (journal article) Cocco, Mattia \| Pellegrini, Carolina \| Martínez-Banaclocha, Helios \| Giorgis, Marta \| Marini, Elisabetta \| Costale, Annalisa \| Miglio, Gianluca \| Fornai, Matteo \| Antonioli, Luca \| López-Castejón, Gloria \| ... \| Bertinaria, Massimo Journal of Medicinal Chemistry, volume 60, issue 9, pages 3656-3671 (2017). 10.1021/acs.jmedchem.6b01624 Cited by (134) \| Cite \| Source \| Open Access
Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds (journal article) Sainas, Stefano \| Pippione, Agnese C. \| Giorgis, Marta \| Lupino, Elisa \| Goyal, Parveen \| Ramondetti, Cristina \| Buccinnà, Barbara \| Piccinini, Marco \| Braga, Rodolpho C. \| Andrade, Carolina H. \| ... \| Lolli, Marco L. European Journal of Medicinal Chemistry, volume 129 (2017). 10.1016/j.ejmech.2017.02.017 Cited by (48) \| Cite \| Source
An evaluation of the antioxidant properties of Arthrospira maxima extracts obtained using non-conventional techniques (journal article) Giorgis, Marta \| Garella, Davide \| Cena, Clara \| Boffa, Luisa \| Cravotto, Giancarlo \| Marini, Elisabetta European Food Research and Technology, volume 243, issue 2, pages 227-237 (2017). 10.1007/s00217-016-2738-5 Cited by (12) \| Cite \| Source