Martina Lepore Signorile

ScholarGPS® ID: 59029998467303

Affiliation

Sapienza University of Rome, Rome, Italy

Affiliation History

Field

Medicine

Discipline

Gastroenterology

Top Specialties

Cancer | Cell Death | Colorectal Cancer

Metrics Summary

Publication Count

Predicted Citations

571

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Understanding the Genetic Landscape of Pancreatic Ductal Adenocarcinoma to Support Personalized Medicine: A Systematic Review (journal article) Pantaleo, Antonino \| Forte, Giovanna \| Fasano, Candida \| Lepore Signorile, Martina \| Sanese, Paola \| De Marco, Katia \| Di Nicola, Elisabetta \| Latrofa, Marialaura \| Grossi, Valentina \| Disciglio, Vittoria \| Simone, Cristiano Cancers, volume 16, issue 1, pages 56- (2023). 10.3390/cancers16010056 Cite \| Source
Classic Galactosemia: Clinical and Computational Characterization of a Novel GALT Missense Variant (p.A303D) and a Literature Review (journal article) Forte, Giovanna \| Buonadonna, Antonia Lucia \| Pantaleo, Antonino \| Fasano, Candida \| Capodiferro, Donatella \| Grossi, Valentina \| Sanese, Paola \| Cariola, Filomena \| De Marco, Katia \| Lepore Signorile, Martina \| ... \| Simone, Cristiano International Journal of Molecular Sciences, volume 24, issue 24, pages 17388- (2023). 10.3390/ijms242417388 Cited by (1) \| Cite \| Source
Uncoupling p38α nuclear and cytoplasmic functions and identification of two p38α phosphorylation sites on β-catenin: implications for the Wnt signaling pathway in CRC models (journal article) Lepore Signorile, Martina \| Fasano, Candida \| Forte, Giovanna \| De Marco, Katia \| Sanese, Paola \| Disciglio, Vittoria \| Di Nicola, Elisabetta \| Pantaleo, Antonino \| Simone, Cristiano \| Grossi, Valentina Cell & Bioscience, volume 13, issue 1 (2023). 10.1186/s13578-023-01175-4 Cited by (1) \| Cite \| Source
SMYD3 Modulates AMPK-mTOR Signaling Balance in Cancer Cell Response to DNA Damage (journal article) Lepore Signorile, Martina \| Sanese, Paola \| Di Nicola, Elisabetta \| Fasano, Candida \| Forte, Giovanna \| De Marco, Katia \| Disciglio, Vittoria \| Latrofa, Marialaura \| Pantaleo, Antonino \| Varchi, Greta \| ... \| Simone, Cristiano Cells, volume 12, issue 22, pages 2644- (2023). 10.3390/cells12222644 Cited by (1) \| Cite \| Source
Tumor Testing and Genetic Analysis to Identify Lynch Syndrome Patients in an Italian Colorectal Cancer Cohort (journal article) Pantaleo, Antonino \| Forte, Giovanna \| Cariola, Filomena \| Valentini, Anna Maria \| Fasano, Candida \| Sanese, Paola \| Grossi, Valentina \| Buonadonna, Antonia Lucia \| De Marco, Katia \| Lepore Signorile, Martina \| ... \| Simone, Cristiano Cancers, volume 15, issue 20, pages 5061- (2023). 10.3390/cancers15205061 Cited by (2) \| Cite \| Source
SMYD3 Modulates the HGF/MET Signaling Pathway in Gastric Cancer (journal article) De Marco, Katia \| Lepore Signorile, Martina \| Di Nicola, Elisabetta \| Sanese, Paola \| Fasano, Candida \| Forte, Giovanna \| Disciglio, Vittoria \| Pantaleo, Antonino \| Varchi, Greta \| Del Rio, Alberto \| ... \| Simone, Cristiano Cells, volume 12, issue 20, pages 2481- (2023). 10.3390/cells12202481 Cite \| Source
Identification of a novel germline APC N-terminal pathogenic variant associated with attenuated familial adenomatous polyposis (journal article) Forte, Giovanna \| Grossi, Valentina \| Cariola, Filomena \| Buonadonna, Antonia Lucia \| Sanese, Paola \| De Marco, Katia \| Fasano, Candida \| Lepore Signorile, Martina \| Disciglio, Vittoria \| Simone, Cristiano Genes & Diseases (2023). 10.1016/j.gendis.2023.101078 Cite \| Source
Coinheritance of germline mutations in APC and MUTYH genes defines the clinical outcome of adenomatous polyposis syndromes (journal article) Forte, Giovanna \| Cariola, Filomena \| Buonadonna, Antonia Lucia \| Guglielmi, Anna Filomena \| Manghisi, Andrea \| De Marco, Katia \| Grossi, Valentina \| Fasano, Candida \| Lepore Signorile, Martina \| Sanese, Paola \| ... \| Simone, Cristiano Genes & Diseases, volume 10, issue 4, pages 1187-1189 (2023). 10.1016/j.gendis.2022.11.017 Cite \| Source
Colorectal Cancer Chemoprevention: A Dream Coming True? (journal article) Lepore Signorile, Martina \| Grossi, Valentina \| Fasano, Candida \| Simone, Cristiano International Journal of Molecular Sciences, volume 24, issue 8, pages 7597- (2023). 10.3390/ijms24087597 Cited by (5) \| Cite \| Source
c-MYC Protein Stability Is Sustained by MAPKs in Colorectal Cancer (journal article) Lepore Signorile, Martina \| Grossi, Valentina \| Fasano, Candida \| Forte, Giovanna \| Disciglio, Vittoria \| Sanese, Paola \| De Marco, Katia \| La Rocca, Francesca \| Armentano, Raffaele \| Valentini, Anna \| ... \| Simone, Cristiano Cancers, volume 14, issue 19, pages 4840- (2022). 10.3390/cancers14194840 Cited by (5) \| Cite \| Source
Identification and Somatic Characterization of the Germline PTEN Promoter Variant rs34149102 in a Family with Gastrointestinal and Breast Tumors (journal article) Disciglio, Vittoria \| Sanese, Paola \| Fasano, Candida \| Lotesoriere, Claudio \| Valentini, Anna \| Forte, Giovanna \| Lepore Signorile, Martina \| De Marco, Katia \| Grossi, Valentina \| Lolli, Ivan \| ... \| Simone, Cristiano Genes, volume 13, issue 4, pages 644- (2022). 10.3390/genes13040644 Cited by (2) \| Cite \| Source
Identifying novel SMYD3 interactors on the trail of cancer hallmarks (journal article) Fasano, Candida \| Lepore Signorile, Martina \| De Marco, Katia \| Forte, Giovanna \| Sanese, Paola \| Grossi, Valentina \| Simone, Cristiano Computational and Structural Biotechnology Journal, volume 20 (2022). 10.1016/j.csbj.2022.03.037 Cited by (7) \| Cite \| Source
Correspondence on “Clinical spectrum of MTOR-related hypomelanosis of Ito with neurodevelopmental abnormalities,” by Carmignac et al. (journal article) Resta, Nicoletta \| Calabrese, Olga \| Grossi, Valentina \| Lugli, Licia \| Simone, Cristiano \| Ranieri, Carlotta \| Piglionica, Marilidia \| Lepore Signorile, Martina \| Rossi, Katia \| Carli, Diana \| Mussa, Alessandro Genetics in Medicine, volume 23, issue 11, pages 2223-2224 (2021). 10.1038/s41436-021-01256-0 Cited by (1) \| Cite \| Source
From Genetics to Histomolecular Characterization: An Insight into Colorectal Carcinogenesis in Lynch Syndrome (journal article) Lepore Signorile, Martina \| Disciglio, Vittoria \| Di Carlo, Gabriella \| Pisani, Antonio \| Simone, Cristiano \| Ingravallo, Giuseppe International Journal of Molecular Sciences, volume 22, issue 13, pages 6767- (2021). 10.3390/ijms22136767 Cited by (13) \| Cite \| Source
Discovery of an Allosteric Ligand Binding Site in SMYD3 Lysine Methyltransferase (journal article) Talibov, Vladimir O. \| Fabini, Edoardo \| FitzGerald, Edward A. \| Tedesco, Daniele \| Cederfelt, Daniela \| Talu, Martin J. \| Rachman, Moira M. \| Mihalic, Filip \| Manoni, Elisabetta \| Naldi, Marina \| ... \| Danielson, U. Helena ChemBioChem, volume 22, issue 9, pages 1597-1608 (2021). 10.1002/cbic.202000736 Cited by (8) \| Cite \| Source
Pharmacological targeting of the novel β-catenin chromatin-associated kinase p38α in colorectal cancer stem cell tumorspheres and organoids (journal article) Lepore Signorile, Martina \| Grossi, Valentina \| Di Franco, Simone \| Forte, Giovanna \| Disciglio, Vittoria \| Fasano, Candida \| Sanese, Paola \| De Marco, Katia \| Susca, Francesco Claudio \| Mangiapane, Laura Rosa \| ... \| Simone, Cristiano Cell Death & Disease, volume 12, issue 4 (2021). 10.1038/s41419-021-03572-4 Cited by (10) \| Cite \| Source
Functional evidence of mTORβ splice variant involvement in the pathogenesis of congenital heart defects (journal article) Gentile, Mattia \| Ranieri, Carlotta \| Loconte, Daria C. \| Ponzi, Emanuela \| Ficarella, Romina \| Volpe, Paolo \| Scalzo, Gabriele \| Lepore Signorile, Martina \| Grossi, Valentina \| Cordella, Angela \| ... \| Resta, Nicoletta Clinical Genetics, volume 99, issue 3, pages 425-429 (2021). 10.1111/cge.13890 Cited by (1) \| Cite \| Source
APC Splicing Mutations Leading to In-Frame Exon 12 or Exon 13 Skipping Are Rare Events in FAP Pathogenesis and Define the Clinical Outcome (journal article) Disciglio, Vittoria \| Forte, Giovanna \| Fasano, Candida \| Sanese, Paola \| Lepore Signorile, Martina \| De Marco, Katia \| Grossi, Valentina \| Cariola, Filomena \| Simone, Cristiano Genes, volume 12, issue 3, pages 353- (2021). 10.3390/genes12030353 Cited by (2) \| Cite \| Source
Targeting SMYD3 to Sensitize Homologous Recombination-Proficient Tumors to PARP-Mediated Synthetic Lethality (journal article) Sanese, Paola \| Fasano, Candida \| Buscemi, Giacomo \| Bottino, Cinzia \| Corbetta, Silvia \| Fabini, Edoardo \| Silvestri, Valentina \| Valentini, Virginia \| Disciglio, Vittoria \| Forte, Giovanna \| ... \| Simone, Cristiano iScience, volume 23, issue 10, pages 101604- (2020). 10.1016/j.isci.2020.101604 Cited by (15) \| Cite \| Source
Gastric polyposis and desmoid tumours as a new familial adenomatous polyposis clinical variant associated with APC mutation at the extreme 3′-end (journal article) Disciglio, Vittoria \| Fasano, Candida \| Cariola, Filomena \| Forte, Giovanna \| Grossi, Valentina \| Sanese, Paola \| Lepore Signorile, Martina \| Resta, Nicoletta \| Lotesoriere, Claudio \| Stella, Alessandro \| ... \| Simone, Cristiano Journal of Medical Genetics, volume 57, issue 5, pages 356-360 (2020). 10.1136/jmedgenet-2019-106299 Cited by (12) \| Cite \| Source