Elizabeth Helgason

ScholarGPS® ID: 58893302911892

Affiliation
Genentech, Inc., South San Francisco, United States
Affiliation History

Field
Life Sciences
Discipline
Biochemistry
Top Specialties
Ubiquitin | Chemical Biology
Metrics Summary
Publication Count
14
Predicted Citations
2,163
Predicted h-index
8
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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N - tert -Butoxycarbonyl- N -(2-(tritylthio)ethoxy)glycine as a Building Block for Peptide Ubiquitination (journal article)
Peng, Lingling | Helgason, Elizabeth | Miranda, Rafael | Tom, Jeffrey | Zhang, Jennifer | Dueber, Erin C. | Song, Aimin
Bioconjugate Chemistry, volume 35, issue 2, pages 245-253 (2024).
10.1021/acs.bioconjchem.3c00541
Cite | Source
Diagnosing and mitigating method-based avidity artifacts that confound polyubiquitin-binding assays (journal article)
Schoeffler, Allyn J. | Helgason, Elizabeth | Popovych, Nataliya | Dueber, Erin C.
Biophysical Reports, volume 1, issue 2, pages 100033- (2021).
10.1016/j.bpr.2021.100033
Cited by (2) | Cite | Source
Primary Amine Tethered Small Molecules Promote the Degradation of X-Linked Inhibitor of Apoptosis Protein (journal article)
den Besten, Willem | Verma, Kshitij | Yamazoe, Sayumi | Blaquiere, Nicole | Phung, Wilson | Izrael-Tomasevic, Anita | Mulvihill, Melinda M. | Helgason, Elizabeth | Prakash, Sumit | Goncharov, Tatiana | ... | Staben, Steven T.
Journal of the American Chemical Society, volume 143, issue 28, pages 10571-10575 (2021).
10.1021/jacs.1c05269
Cited by (9) | Cite | Source
Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9 (journal article)
Holliday, Michael J. | Ferrao, Ryan | de Leon Boenig, Gladys | Estevez, Alberto | Helgason, Elizabeth | Rohou, Alexis | Dueber, Erin C. | Fairbrother, Wayne J.
Journal of Biological Chemistry, volume 293, issue 43, pages 16803-16817 (2018).
10.1074/jbc.RA118.004821
Cited by (8) | Cite | Source
Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9. (journal article)
Holliday, M.J. | Ferrao, R. | Boenig, G. de Leon | Estevez, A. | Helgason, E. | Rohou, A. | Dueber, E.C. | Fairbrother, W.J.
Journal of Biological Chemistry, volume 293, issue 43, pages 16803-16817 (2018).
10.2210/pdb6e26/pdb
Cite | Source
Conformational dynamics control ubiquitin-deubiquitinase interactions and influence in vivo signaling (journal article)
Phillips, Aaron H. | Zhang, Yingnan | Cunningham, Christian N. | Zhou, Lijuan | Forrest, William F. | Liu, Peter S. | Steffek, Micah | Lee, James | Tam, Christine | Helgason, Elizabeth | ... | Corn, Jacob E.
Proceedings of the National Academy of Sciences, volume 110, issue 28, pages 11379-11384 (2013).
10.1073/pnas.1302407110
Cited by (47) | Cite | Source | Open Access
Recent insights into the complexity of Tank‐binding kinase 1 signaling networks: The emerging role of cellular localization in the activation and substrate specificity of TBK1 (journal article)
Helgason, Elizabeth | Phung, Qui T. | Dueber, Erin C.
FEBS Letters, volume 587, issue 8, pages 1230-1237 (2013).
10.1016/j.febslet.2013.01.059
Cited by (150) | Cite | Source | Open Access
Erratum: Corrigendum: Conformational stabilization of ubiquitin yields potent and selective inhibitors of USP7 (journal article)
Zhang, Yingnan | Zhou, Lijuan | Rouge, Lionel | Phillips, Aaron H | Lam, Cynthia | Liu, Peter | Sandoval, Wendy | Helgason, Elizabeth | Murray, Jeremy M | Wertz, Ingrid E | Corn, Jacob E
Nature Chemical Biology, volume 9, issue 3, pages 192-192 (2013).
10.1038/nchembio0313-192b
Cited by (5) | Cite | Source | Open Access
Conformational stabilization of ubiquitin yields potent and selective inhibitors of USP7 (journal article)
Zhang, Yingnan | Zhou, Lijuan | Rouge, Lionel | Phillips, Aaron H | Lam, Cynthia | Liu, Peter | Sandoval, Wendy | Helgason, Elizabeth | Murray, Jeremy M | Wertz, Ingrid E | Corn, Jacob E
Nature Chemical Biology, volume 9, issue 1, pages 51-58 (2013).
10.1038/nchembio.1134
Cited by (90) | Cite | Source
Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation (journal article)
Ma, Xiaolei | Helgason, Elizabeth | Phung, Qui T. | Quan, Clifford L. | Iyer, Rekha S. | Lee, Michelle W. | Bowman, Krista K. | Starovasnik, Melissa A. | Dueber, Erin C.
Proceedings of the National Academy of Sciences, volume 109, issue 24, pages 9378-9383 (2012).
10.1073/pnas.1121552109
Cited by (173) | Cite | Source | Open Access
Preparation of Distinct Ubiquitin Chain Reagents of High Purity and Yield (journal article)
Dong, Ken C. | Helgason, Elizabeth | Yu, Christine | Phu, Lilian | Arnott, David P. | Bosanac, Ivan | Compaan, Deanne M. | Huang, Oscar W. | Fedorova, Anna V. | Kirkpatrick, Donald S. | ... | Dueber, Erin C.
Structure, volume 19, issue 8, pages 1053-1063 (2011).
10.1016/j.str.2011.06.010
Cited by (76) | Cite | Source | Open Access
Erratum: Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7 (journal article)
Wertz, Ingrid E. | Kusam, Saritha | Lam, Cynthia | Okamoto, Toru | Sandoval, Wendy | Anderson, Daniel J. | Helgason, Elizabeth | Ernst, James A. | Eby, Mike | Liu, Jinfeng | ... | Dixit, Vishva M.
Nature, volume 475, issue 7354, pages 122-122 (2011).
10.1038/nature10133
Cited by (3) | Cite | Source | Open Access
Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7 (journal article)
Wertz, Ingrid E. | Kusam, Saritha | Lam, Cynthia | Okamoto, Toru | Sandoval, Wendy | Anderson, Daniel J. | Helgason, Elizabeth | Ernst, James A. | Eby, Mike | Liu, Jinfeng | ... | Dixit, Vishva M.
Nature, volume 471, issue 7336, pages 110-114 (2011).
10.1038/nature09779
Cited by (638) | Cite | Source
c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling (journal article)
Dynek, Jasmin N | Goncharov, Tatiana | Dueber, Erin C | Fedorova, Anna V | Izrael-Tomasevic, Anita | Phu, Lilian | Helgason, Elizabeth | Fairbrother, Wayne J | Deshayes, Kurt | Kirkpatrick, Donald S | Vucic, Domagoj
The EMBO Journal, volume 29, issue 24, pages 4198-4209 (2010).
10.1038/emboj.2010.300
Cited by (296) | Cite | Source | Open Access