Maxwell D. Cummings

ScholarGPS® ID: 58822196922264

Affiliation

Johnson & Johnson, New Brunswick, New Jersey, United States

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

4,509

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Discovery of a novel series of guanidinebenzoates as gut-restricted enteropeptidase and trypsin dual inhibitors for the treatment of metabolic syndrome (journal article) Zhang, Xuqing \| Zhu, Bin \| Sun, Weimei \| Wang, Mina \| Albarazanji, Kamal \| Ghosh, Brahma \| Cummings, Maxwell \| Lenhard, James \| Leonard, James \| Macielag, Mark \| Lanter, James Bioorganic & Medicinal Chemistry Letters, volume 40 (2021). 10.1016/j.bmcl.2021.127939 Cited by (2) \| Cite \| Source
Targeting Enteropeptidase with Reversible Covalent Inhibitors To Achieve Metabolic Benefits (journal article) Sun, Weimei \| Zhang, Xuqing \| Cummings, Maxwell D. \| Albarazanji, Kamal \| Wu, Jiejun \| Wang, Mina \| Alexander, Richard \| Zhu, Bin \| Zhang, YueMei \| Leonard, James \| ... \| Lenhard, James Journal of Pharmacology and Experimental Therapeutics, volume 375, issue 3, pages 510-521 (2020). 10.1124/jpet.120.000219 Cited by (14) \| Cite \| Source
Discovery and optimization of new oxadiazole substituted thiazole RORγt inverse agonists through a bioisosteric amide replacement approach (journal article) Steeneck, Christoph \| Gege, Christian \| Kinzel, Olaf \| Albers, Michael \| Kleymann, Gerald \| Schlüter, Thomas \| Schulz, Andreas \| Xue, Xiaohua \| Cummings, Maxwell D. \| Fourie, Anne M. \| ... \| Goldberg, Steven D. Bioorganic & Medicinal Chemistry Letters, volume 30, issue 12, pages 127174- (2020). 10.1016/j.bmcl.2020.127174 Cited by (11) \| Cite \| Source
Optimization and biological evaluation of thiazole-bis-amide inverse agonists of RORγt (journal article) Gege, Christian \| Albers, Michael \| Kinzel, Olaf \| Kleymann, Gerald \| Schlüter, Thomas \| Steeneck, Christoph \| Hoffmann, Thomas \| Xue, Xiaohua \| Cummings, Maxwell D. \| Spurlino, John \| ... \| Goldberg, Steven D. Bioorganic & Medicinal Chemistry Letters, volume 30, issue 12, pages 127205- (2020). 10.1016/j.bmcl.2020.127205 Cited by (12) \| Cite \| Source
Alkyl linked quinolinyl modulators of RORγt (patent) Leonard, Kristi A. \| Barbay, Kent \| Edwards, James P. \| Kreutter, Kevin D. \| Kummer, David A. \| Maharoof, Umar \| Nishimura, Rachel \| Urbanski, Maud \| Venkatesan, Hariharan \| Wang, Aihua \| ... \| Cummings, Maxwell D. Patent Number: 10555941 (2020) Cite \| Source
Discovery and optimization of a series of small-molecule allosteric inhibitors of MALT1 protease (journal article) Lu, Tianbao \| Connolly, Peter J. \| Philippar, Ulrike \| Sun, Weimei \| Cummings, Maxwell D. \| Barbay, Kent \| Gys, Luc \| Van Nuffel, Luc \| Austin, Nigel \| Bekkers, Mariette \| ... \| Edwards, James Bioorganic & Medicinal Chemistry Letters, volume 29, issue 23, pages 126743- (2019). 10.1016/j.bmcl.2019.126743 Cited by (10) \| Cite \| Source
Structure-Based Macrocycle Design in Small-Molecule Drug Discovery and Simple Metrics To Identify Opportunities for Macrocyclization of Small-Molecule Ligands (journal article) Cummings, Maxwell D. \| Sekharan, Sivakumar Journal of Medicinal Chemistry, volume 62, issue 15, pages 6843-6853 (2019). 10.1021/acs.jmedchem.8b01985 Cited by (78) \| Cite \| Source
Phenyl linked quinolinyl modulators of RORγt (patent) Leonard, Kristi A. \| Barbay, Kent \| Edwards, James P. \| Kreutter, Kevin D. \| Kummer, David A. \| Maharoof, Umar \| Nishimura, Rachel \| Urbanski, Maud \| Venkatesan, Hariharan \| Wang, Aihua \| ... \| Cummings, Maxwell D. Patent Number: 10369146 (2019) Cite \| Source
Quinolinyl modulators of RORγt (patent) Leonard, Kristi A. \| Barbay, Kent \| Edwards, James P. \| Kreutter, Kevin D. \| Kummer, David A. \| Maharoof, Umar \| Nishimura, Rachel \| Urbanski, Maud \| Venkatesan, Hariharan \| Wang, Aihua \| ... \| Tanis, Virginia Patent Number: 10201546 (2019) Cite \| Source
Conformational Sampling of Macrocyclic Drugs in Different Environments: Can We Find the Relevant Conformations? (journal article) Poongavanam, Vasanthanathan \| Danelius, Emma \| Peintner, Stefan \| Alcaraz, Lilian \| Caron, Giulia \| Cummings, Maxwell D. \| Wlodek, Stanislaw \| Erdelyi, Mate \| Hawkins, Paul C. D. \| Ermondi, Giuseppe \| Kihlberg, Jan ACS Omega, volume 3, issue 9, pages 11742-11757 (2018). 10.1021/acsomega.8b01379 Cited by (72) \| Cite \| Source \| Open Access
Design and synthesis of a series of bioavailable fatty acid synthase (FASN) KR domain inhibitors for cancer therapy (journal article) Lu, Tianbao \| Schubert, Carsten \| Cummings, Maxwell D. \| Bignan, Gilles \| Connolly, Peter J. \| Smans, Karine \| Ludovici, Donald \| Parker, Michael H. \| Meyer, Christophe \| Rocaboy, Christian \| ... \| Meerpoel, Lieven Bioorganic & Medicinal Chemistry Letters, volume 28, issue 12, pages 2159-2164 (2018). 10.1016/j.bmcl.2018.05.014 Cited by (27) \| Cite \| Source
Identification and biological evaluation of thiazole-based inverse agonists of RORγt (journal article) Gege, Christian \| Cummings, Maxwell D. \| Albers, Michael \| Kinzel, Olaf \| Kleymann, Gerald \| Schlüter, Thomas \| Steeneck, Christoph \| Nelen, Marina I. \| Milligan, Cindy \| Spurlino, John \| ... \| Hoffmann, Thomas Bioorganic & Medicinal Chemistry Letters, volume 28, issue 9, pages 1446-1455 (2018). 10.1016/j.bmcl.2018.03.093 Cited by (19) \| Cite \| Source
Identification and biological evaluation of thiazole-based inverse agonists of ROR gamma t. (journal article) Gege, Christian \| Cummings, Maxwell D. \| Albers, Michael \| Kinzel, Olaf \| Kleymann, Gerald \| Schlüter, Thomas \| Steeneck, Christoph \| Nelen, Marina I. \| Milligan, Cindy \| Spurlino, John \| ... \| Hoffmann, Thomas Bioorganic & Medicinal Chemistry Letters, volume 28, issue 9, pages 1446-1455 (2018). 10.2210/pdb6cvh/pdb Cite \| Source
6-Substituted quinolines as RORγt inverse agonists (journal article) Barbay, J. Kent \| Cummings, Maxwell D. \| Abad, Marta \| Castro, Glenda \| Kreutter, Kevin D. \| Kummer, David A. \| Maharoof, Umar \| Milligan, Cynthia \| Nishimura, Rachel \| Pierce, Joan \| ... \| Leonard, Kristi Bioorganic & Medicinal Chemistry Letters, volume 27, issue 23, pages 5277-5283 (2017). 10.1016/j.bmcl.2017.10.027 Cited by (23) \| Cite \| Source
Identification and structure activity relationships of quinoline tertiary alcohol modulators of RORγt (journal article) Kummer, David A. \| Cummings, Maxwell D. \| Abad, Marta \| Barbay, Joseph \| Castro, Glenda \| Wolin, Ronald \| Kreutter, Kevin D. \| Maharoof, Umar \| Milligan, Cynthia \| Nishimura, Rachel \| ... \| Leonard, Kristi Bioorganic & Medicinal Chemistry Letters, volume 27, issue 9, pages 2047-2057 (2017). 10.1016/j.bmcl.2017.02.044 Cited by (25) \| Cite \| Source
Quinolinyl modulators of RORγt (patent) Leonard, Kristi A. \| Barbay, Kent \| Edwards, James P. \| Kreutter, Kevin D. \| Kummer, David A. \| Maharoof, Umar \| Nishimura, Rachel \| Urbanski, Maud \| Venkatesan, Hariharan \| Wang, Aihua \| ... \| Tanis, Virginia Patent Number: 9624225 (2017) Cited by (3) \| Cite \| Source
Phenyl linked quinolinyl modulators of RORγt (patent) Leonard, Kristi A. \| Barbay, Kent \| Edwards, James P. \| Kreutter, Kevin D. \| Kummer, David A. \| Maharoof, Umar \| Nishimura, Rachel \| Urbanski, Maud \| Venkatesan, Hariharan \| Wang, Aihua \| ... \| Cummings, Maxwell D. Patent Number: 9403816 (2016) Cited by (4) \| Cite \| Source
Alkyl linked quinolinyl modulators of RORγt (patent) Leonard, Kristi A. \| Barbay, Kent \| Edwards, James P. \| Kreutter, Kevin D. \| Kummer, David A. \| Maharoof, Umar \| Nishimura, Rachel \| Urbanski, Maud \| Venkatesan, Hariharan \| Wang, Aihua \| ... \| Cummings, Maxwell D. Patent Number: 9346782 (2016) Cited by (3) \| Cite \| Source
Heteroaryl linked quinolinyl modulators of RORgammat (patent) Leonard, Kristi A. \| Barbay, Kent \| Edwards, James P. \| Kreutter, Kevin D. \| Kummer, David A. \| Maharoof, Umar \| Nishimura, Rachel \| Urbanski, Maud \| Venkatesan, Hariharan \| Wang, Aihua \| ... \| Cummings, Maxwell D. Patent Number: 9328095 (2016) Cited by (3) \| Cite \| Source
Methylene linked quinolinyl modulators of RORγt (patent) Leonard, Kristi A. \| Barbay, Kent \| Edwards, James P. \| Kreutter, Kevin D. \| Kummer, David A. \| Maharoof, Umar \| Nishimura, Rachel \| Urbanski, Maud \| Venkatesan, Hariharan \| Wang, Aihua \| ... \| Goldberg, Steven Patent Number: 9284308 (2016) Cited by (5) \| Cite \| Source