Brigitte T. Huber

ScholarGPS® ID: 58411908503621

Affiliation

Tufts University, Medford and Somerville, United States

Affiliation History

Field

Medicine

Discipline

Pathology

Top Specialties

Metrics Summary

Publication Count

164

Predicted Citations

7,681

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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γδT Cells Are Prevalent in the Proximal Aorta and Drive Nascent Atherosclerotic Lesion Progression and Neutrophilia in Hypercholesterolemic Mice (journal article) Vu, Duc M. \| Tai, Albert \| Tatro, Jeffrey B. \| Karas, Richard H. \| Huber, Brigitte T. \| Beasley, Debbie PLoS ONE, volume 9, issue 10, pages e109416- (2014). 10.1371/journal.pone.0109416 Cited by (31) \| Cite \| Source \| Open Access
Autoimmunity in Lyme Arthritis: Molecular Mimicry between OspA and LFA-1 (book chapter) In Molecular Mimicry, Microbes, and Autoimmunity Gross, Dawn M. \| Huber, Brigitte T. ASM Press (2014) 10.1128/9781555818074.ch12 Cite \| Source
Viral Superantigens in Mice and Humans (book chapter) In Superantigens Tai, Albert K. \| Huber, Brigitte T. ASM Press (2014) 10.1128/9781555815844.ch4 Cite \| Source
Human Endogenous Retrovirus-K18 Superantigen Expression and Human Herpesvirus-6 and Human Herpesvirus-7 Viral Loads in Chronic Fatigue Patients (journal article) Oakes, Brendan \| Hoagland-Henefield, Matthias \| Komaroff, Anthony L. \| Erickson, Jessica L. \| Huber, Brigitte T. Clinical Infectious Diseases, volume 56, issue 10, pages 1394-1400 (2013). 10.1093/cid/cit086 Cited by (18) \| Cite \| Source \| Open Access
Autophagy: a dichotomous player in Toll-like receptor 7-mediated autoimmunity. (P4073) (journal article) Weindel, Chi \| Richey, Lauren \| Bolland, Silvia \| Huber, Brigitte The Journal of Immunology, volume 190, issue 1_Supplement, pages 127.8-127.8 (2013). 10.4049/jimmunol.190.Supp.127.8 Cite \| Source
Th17 differentiation is the default program for DPP2‐deficient T‐cell differentiation (journal article) Mele, Deanna A. \| Sampson, James F. \| Huber, Brigitte T. European Journal of Immunology, volume 41, issue 6, pages 1583-1593 (2011). 10.1002/eji.201041157 Cited by (6) \| Cite \| Source \| Open Access
Exogenous and endogenous virus interactions in head and neck cancer immunity (105.34) (journal article) Sutkowski, Natalie \| Hoel, Brian \| Gibbs, Kevin \| Sun, Wei \| Halstead, Lucinda \| Huber, Brigitte \| Garrett-Mayer, Elizabeth \| Hill, Elizabeth \| Gillespie, M. \| Rubinchik, Semyon The Journal of Immunology, volume 186, issue 1_Supplement, pages 105.34-105.34 (2011). 10.4049/jimmunol.186.Supp.105.34 Cite \| Source
Human complement receptor type 2 (CR2/CD21) transgenic mice provide an in vivo model to study immunoregulatory effects of receptor antagonists (journal article) Kulik, Liudmila \| Chen, Kuan \| Huber, Brigitte T. \| Holers, V. Michael Molecular Immunology, volume 48, issue 6-7, pages 883-894 (2011). 10.1016/j.molimm.2010.12.019 Cited by (13) \| Cite \| Source
Failure to Detect XMRV-Specific Antibodies in the Plasma of CFS Patients Using Highly Sensitive Chemiluminescence Immunoassays (journal article) Oakes, Brendan \| Qiu, Xiaoxing \| Levine, Susan \| Hackett, John \| Huber, Brigitte T. Advances in Virology, volume 2011 (2011). 10.1155/2011/854540 Cited by (7) \| Cite \| Source \| Open Access
Dipeptidyl peptidase 2 apoptosis assay determines the B-cell activation stage and predicts prognosis in chronic lymphocytic leukemia (journal article) Danilov, Alexey V. \| Danilova, Olga V. \| Brown, Jennifer R. \| Rabinowitz, Arthur \| Klein, Andreas K. \| Huber, Brigitte T. Experimental Hematology, volume 38, issue 12, pages 1167-1177 (2010). 10.1016/j.exphem.2010.08.008 Cited by (12) \| Cite \| Source \| Open Access
Contamination of human DNA samples with mouse DNA can lead to false detection of XMRV-like sequences (journal article) Oakes, Brendan \| Tai, Albert K \| Cingöz, Oya \| Henefield, Madeleine H \| Levine, Susan \| Coffin, John M \| Huber, Brigitte T Retrovirology, volume 7, issue 1 (2010). 10.1186/1742-4690-7-109 Cited by (118) \| Cite \| Source \| Open Access
Autoimmunity (book chapter) In Topley & Wilson's Microbiology and Microbial Infections Crowley, Helena \| Huber, Brigitte T. John Wiley & Sons, Ltd (2010) 10.1002/9780470688618.taw0118 Cite \| Source
Infectious arthritis and immune dysregulation: lessons from Lyme disease (journal article) Iliopoulou, Bettina Panagiota \| Huber, Brigitte T Current Opinion in Rheumatology, volume 22, issue 4, pages 451-455 (2010). 10.1097/BOR.0b013e328338f73f Cited by (10) \| Cite \| Source
HLA–DR alleles determine responsiveness to Borrelia burgdorferi antigens in a mouse model of self‐perpetuating arthritis (journal article) Iliopoulou, Bettina Panagiota \| Guerau‐De‐Arellano, Mireia \| Huber, Brigitte T. Arthritis & Rheumatism, volume 60, issue 12, pages 3831-3840 (2009). 10.1002/art.25005 Cited by (34) \| Cite \| Source \| Open Access
Neurogenin 3-Specific Dipeptidyl Peptidase-2 Deficiency Causes Impaired Glucose Tolerance, Insulin Resistance, and Visceral Obesity (journal article) Danilova, Olga V. \| Tai, Albert K. \| Mele, Deanna A. \| Beinborn, Martin \| Leiter, Andrew B. \| Greenberg, Andrew S. \| Perfield, James W. \| DeFuria, Jason \| Singru, Praful S. \| Lechan, Ronald M. \| Huber, Brigitte T. Endocrinology, volume 150, issue 12, pages 5240-5248 (2009). 10.1210/en.2009-0386 Cited by (14) \| Cite \| Source \| Open Access
HHV-6A infection induces expression of HERV-K18-encoded superantigen (journal article) Tai, Albert K. \| Luka, Janos \| Ablashi, Dharam \| Huber, Brigitte T. Journal of Clinical Virology, volume 46, issue 1, pages 47-48 (2009). 10.1016/j.jcv.2009.05.019 Cited by (68) \| Cite \| Source
Emergence of chronic Lyme arthritis: Putting the breaks on CD28 costimulation (journal article) Iliopoulou, Bettina Panagiota \| Huber, Brigitte T. Immunopharmacology and Immunotoxicology, volume 31, issue 2, pages 180-185 (2009). 10.1080/08923970802391459 Cited by (2) \| Cite \| Source
Vitamin E Reverses Impaired Linker for Activation of T Cells Activation in T Cells from Aged C57BL/6 Mice (journal article) Marko, Melissa G. \| Pang, Hoan-Jen E. \| Ren, Zhihong \| Azzi, Angelo \| Huber, Brigitte T. \| Bunnell, Stephen C. \| Meydani, Simin Nikbin The Journal of Nutrition, volume 139, issue 6, pages 1192-1197 (2009). 10.3945/jn.108.103416 Cited by (34) \| Cite \| Source \| Open Access
EBV LMP-2A employs a novel mechanism to transactivate the HERV-K18 superantigen through its ITAM (journal article) Hsiao, Francis C. \| Tai, Albert K. \| Deglon, Agnes \| Sutkowski, Natalie \| Longnecker, Richard \| Huber, Brigitte T. Virology, volume 385, issue 1, pages 261-266 (2009). 10.1016/j.virol.2008.11.025 Cited by (44) \| Cite \| Source \| Open Access
Persistent arthritis in Borrelia burgdorferi– infected HLA–DR4–positive CD28‐negative mice post–antibiotic treatment (journal article) Iliopoulou, Bettina Panagiota \| Alroy, Joseph \| Huber, Brigitte T. Arthritis & Rheumatism, volume 58, issue 12, pages 3892-3901 (2008). 10.1002/art.24028 Cited by (24) \| Cite \| Source \| Open Access

Title	Investigators	Year	Expiration	Amount
Molecular Characterization of Mls-a Determinants	Huber, Brigitte	04-01-1990	09-30-1992	$150,000
B Cell Differentiation Antigens: Structure and Assembly	Huber, Brigitte	09-01-1981	02-29-1984	$90,000

Title	Investigators	Year	Cost	Agency
HERV-K18 as a Risk Factor for CFIDS	Huber, Brigitte T.	2011	$295,269	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
HERV-K18 as a Risk Factor for CFIDS	Huber, Brigitte T.	2010	$307,572	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
HERV-K18 as a Risk Factor for CFIDS	Huber, Brigitte T.	2009	$310,679	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
TARGETS FOR AUTOANTIBODIES FROM SYNOVIAL LESIONS IN CHRONIC LYME ARTHRITIS	Huber, Brigitte T.	2008	$5,187	NATIONAL CENTER FOR RESEARCH RESOURCES
IDENTIFICATION OF TREATMENT-RESISTANT LYME ARTHRITIS AUTOANTIGENS	Huber, Brigitte T.	2008	$5,187	NATIONAL CENTER FOR RESEARCH RESOURCES
HERV-K18 as a Risk Factor for CFIDS	Huber, Brigitte T.	2008	$310,315	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
B Lymphocytes Differentiation and Triggering	Huber, Brigitte T.	2008	$468,895	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
TARGETS FOR AUTOANTIBODIES FROM SYNOVIAL LESIONS IN CHRONIC LYME ARTHRITIS	Huber, Brigitte T.	2007	$8,619	NATIONAL CENTER FOR RESEARCH RESOURCES
IDENTIFICATION OF TREATMENT-RESISTANT LYME ARTHRITIS AUTOANTIGENS	Huber, Brigitte T.	2007	$8,619	NATIONAL CENTER FOR RESEARCH RESOURCES
HERV-K18 as a Risk Factor for CFIDS	Huber, Brigitte T.	2007	$332,184	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
B Lymphocytes Differentiation and Triggering	Huber, Brigitte T.	2007	$464,055	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
QPP: Protease that Prevents Apoptosis in Quiescent Cells	Huber, Brigitte T.	2007	$300,573	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
IDENTIFICATION OF TREATMENT-RESISTANT LYME ARTHRITIS AUTOANTIGENS	Huber, Brigitte T.	2006	$11,330	NATIONAL CENTER FOR RESEARCH RESOURCES
QPP: Protease that Prevents Apoptosis in Quiescent Cells	Huber, Brigitte T.	2006	$309,551	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
B Lymphocytes Differentiation and Triggering	Huber, Brigitte T.	2006	$463,996	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
IDENTIFICATION OF IN VIVO SUBSTRATES OF SERINE PROTEASE QPP BY MASS SPECTROMETR	Huber, Brigitte T.	2006	$27,332	NATIONAL CENTER FOR RESEARCH RESOURCES
IDENTIFICATION OF IN VIVO SUBSTRATES OF SERINE PROTEASE QPP BY MASS SPECTROMETR	Huber, Brigitte T.	2005	$27,261	NATIONAL CENTER FOR RESEARCH RESOURCES
IDENTIFICATION OF TREATMENT-RESISTANT LYME ARTHRITIS AUTOANTIGENS	Huber, Brigitte T.	2005	$11,301	NATIONAL CENTER FOR RESEARCH RESOURCES
B Lymphocytes Differentiation and Triggering	Huber, Brigitte T.	2005	$461,322	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Chronic Lyme Arthritis: Is this Autoimmunity?	Huber, Brigitte T.	2005	$317,000	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
QPP: Protease that Prevents Apoptosis in Quiescent Cells	Huber, Brigitte T.	2005	$317,000	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
B Lymphocytes Differentiation and Triggering	Huber, Brigitte T.	2004	$458,318	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
IDENTIFICATION OF IN VIVO SUBSTRATES OF SERINE PROTEASE QPP BY MASS SPECTROMETRY	Huber, Brigitte T.	2004	$24,880	NATIONAL CENTER FOR RESEARCH RESOURCES
Chronic Lyme Arthritis: Is this Autoimmunity?	Huber, Brigitte T.	2004	$317,000	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
QPP: Protease that Prevents Apoptosis in Quiescent Cells	Huber, Brigitte T.	2004	$317,000	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
QPP: Protease that Prevents Apoptosis in Quiescent Cells	Huber, Brigitte T.	2003	$180,803	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Chronic Lyme Arthritis: Is this Autoimmunity?	Huber, Brigitte T.	2003	$317,000	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Chronic Lyme Arthritis: Is this Autoimmunity?	Huber, Brigitte T.	2002	$317,000	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Chronic Lyme Arthritis: Is this Autoimmunity?	Huber, Brigitte T.	2001	$317,000	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
PROTEASE THAT PREVENTS APOPTOSIS IN QUIESCENT CELLS	Huber, Brigitte T.	2001	$293,098	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
CHRONIC LYME ARTHRITIS--IS THIS AUTOIMMUNITY?	Huber, Brigitte T.	2000	$235,932	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
PROTEASE THAT PREVENTS APOPTOSIS IN QUIESCENT CELLS	Huber, Brigitte T.	2000	$282,857	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
CHRONIC LYME ARTHRITIS--IS THIS AUTOIMMUNITY?	Huber, Brigitte T.	1999	$229,059	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
PROTEASE THAT PREVENTS APOPTOSIS IN QUIESCENT CELLS	Huber, Brigitte T.	1999	$288,211	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
CHRONIC LYME ARTHRITIS--IS THIS AUTOIMMUNITY?	Huber, Brigitte T.	1998	$227,647	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
B LYMPHOCYTES: DIFFERENTIATION AND TRIGGERING	Huber, Brigitte T.	1988	$234,121	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
B LYMPHOCYTES: DIFFERENTIATION AND TRIGGERING	Huber, Brigitte T.	1987	$231,230	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
B LYMPHOCYTES: DIFFERENTIATION AND TRIGGERING	Huber, Brigitte T.	1986	$205,249	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
B CELL DIFFERENTIATION ANTIGENS: FUNCTION AND STRUCTURE	Huber, Brigitte T.	1986	$53,136	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
B CELL DIFFERENTIATION ANTIGENS: FUNCTION AND STRUCTURE	Huber, Brigitte T.	1985	$52,218	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES