Christian Schöneich

ScholarGPS® ID: 58329060263931

Affiliation
University of Kansas, Lawrence, United States
Affiliation History

Field
Pharmacy and Pharmaceutical Sciences
Discipline
Pharmaceutical Sciences
Top Specialties
Peptide | Physical Chemistry | Proteomics | Antibody | Hormone | Growth Hormone | Mass Spectrometry | Alzheimer's Disease | Monoclonal Antibody | Radical Ion | Sarcoplasmic Reticulum | Hydroxyl Radical | Side Chain | Antioxidant | Biophysics
Metrics Summary
Publication Count
299
Predicted Citations
17,757
Predicted h-index
77
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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Near UV Photodegradation Mechanisms of Amino Acid Excipients: Formation of the Carbon Dioxide Radical Anion from Aspartate and Fe(III) (journal article)
Zhang, Yilue | Wu, Yaqi | Schöneich, Christian
Molecular Pharmaceutics, volume 21, issue 3, pages 1233-1245 (2024).
10.1021/acs.molpharmaceut.3c00893
Cited by (2) | Cite | Source
Molecular Dynamics Simulation of an Iron(III) Binding Site on the Fc Domain of IgG1 Relevant for Visible Light-Induced Protein Fragmentation (journal article)
Lou, Hao | Zhang, Yilue | Kuczera, Krzysztof | Hageman, Michael J. | Schöneich, Christian
Molecular Pharmaceutics, volume 21, issue 2, pages 501-512 (2024).
10.1021/acs.molpharmaceut.3c00612
Cite | Source
Protection against Aβ-induced neuronal damage by KU-32: PDHK1 inhibition as important target (journal article)
Pal, Ranu | Hui, Dongwei | Menchen, Heather | Zhao, Huiping | Mozziconacci, Olivier | Wilkins, Heather | Blagg, Brian S. J. | Schöneich, Christian | Swerdlow, Russell H. | Michaelis, Mary L. | Michaelis, Elias K.
Frontiers in Aging Neuroscience, volume 15 (2023).
10.3389/fnagi.2023.1282855
Cited by (1) | Cite | Source
Near UV light photo-degradation of histidine buffer: Mechanisms and role of Fe(III) (journal article)
Zhang, Yilue | Schöneich, Christian
European Journal of Pharmaceutics and Biopharmaceutics, volume 190 (2023).
10.1016/j.ejpb.2023.08.001
Cited by (3) | Cite | Source
Photo-induced site-specific oxidative fragmentation of IgG1 mediated by iron(III)-containing histidine buffer: Mechanistic studies and excipient effects (journal article)
Zhang, Yilue | Ballesteros, Maribel Espinoza | Schöneich, Christian
European Journal of Pharmaceutics and Biopharmaceutics, volume 190 (2023).
10.1016/j.ejpb.2023.07.011
Cited by (2) | Cite | Source
In-Depth Characterization of Acidic Variants Induced by Metal-Catalyzed Oxidation in a Recombinant Monoclonal Antibody (journal article)
Yang, Yi | Zhang, Fan | Gan, Yutian | Zhang, Hui-Min | Liu, Peilu | Mah, Anna | Gennaro, Lynn | Schöneich, Christian
Analytical Chemistry, volume 95, issue 14, pages 5867-5876 (2023).
10.1021/acs.analchem.2c04414
Cited by (3) | Cite | Source
Designing Formulation Strategies for Enhanced Stability of Therapeutic Peptides in Aqueous Solutions: A Review (journal article)
Nugrahadi, Primawan Putra | Hinrichs, Wouter L. J. | Frijlink, Henderik W. | Schöneich, Christian | Avanti, Christina
Pharmaceutics, volume 15, issue 3, pages 935- (2023).
10.3390/pharmaceutics15030935
Cited by (12) | Cite | Source
The Storage and In-Use Stability of mRNA Vaccines and Therapeutics: Not A Cold Case (journal article)
Oude Blenke, Erik | Örnskov, Eivor | Schöneich, Christian | Nilsson, Gunilla A. | Volkin, David B. | Mastrobattista, Enrico | Almarsson, Örn | Crommelin, Daan J.A.
Journal of Pharmaceutical Sciences, volume 112, issue 2, pages 386-403 (2023).
10.1016/j.xphs.2022.11.001
Cited by (60) | Cite | Source
Visible Light Induces Site-Specific Oxidative Heavy Chain Fragmentation of a Monoclonal Antibody (IgG1) Mediated by an Iron(III)-Containing Histidine Buffer (journal article)
Zhang, Yilue | Schöneich, Christian
Molecular Pharmaceutics, volume 20, issue 1, pages 650-662 (2023).
10.1021/acs.molpharmaceut.2c00840
Cited by (11) | Cite | Source
Contributors (book chapter)
In Surfactants in Biopharmaceutical Development
Bell, Christian H. | Corvari, Vincent | Gomes, Diana C. | Grapentin, Christoph | Heitz, Marc | Huang, Lihua | Jahn, Michael | Khan, Tarik A. | Koulov, Atanas V. | Mahler, Hanns-Christian | ... | Singh, Satish K.
Elsevier (2023)
10.1016/B978-0-12-812503-8.01002-2
Cite | Source
Oxidative degradation of surfactants: mechanisms (book chapter)
In Surfactants in Biopharmaceutical Development
Schöneich, Christian
Elsevier (2023)
10.1016/B978-0-12-812503-8.00006-3
Cite | Source
Near-UV and Visible Light Degradation of Iron (III)-Containing Citrate Buffer: Formation of Carbon Dioxide Radical Anion via Fragmentation of a Sterically Hindered Alkoxyl Radical (journal article)
Zhang, Yilue | Richards, David S. | Grotemeyer, Elizabeth N. | Jackson, Timothy A. | Schöneich, Christian
Molecular Pharmaceutics, volume 19, issue 11, pages 4026-4042 (2022).
10.1021/acs.molpharmaceut.2c00501
Cited by (12) | Cite | Source
Impact of various factors on the kinetics of non-enzymatic fragmentation of a monoclonal antibody (journal article)
Gupta, Surbhi | Upadhyay, Kratika | Schöneich, Christian | Rathore, Anurag S
European Journal of Pharmaceutics and Biopharmaceutics, volume 178 (2022).
10.1016/j.ejpb.2022.08.002
Cited by (6) | Cite | Source
Intra-Micellar and Extra-Micellar Oxidation in Phosphate and Histidine Buffers Containing Polysorbate 80 (journal article)
Peters, Björn-Hendrik | Wei, Yangjie | Middaugh, C. Russell | Schöneich, Christian
Journal of Pharmaceutical Sciences, volume 111, issue 9, pages 2435-2444 (2022).
10.1016/j.xphs.2022.06.011
Cited by (2) | Cite | Source
Advanced Oxidation Processes in Pharmaceutical Formulations: Photo-Fenton Degradation of Peptides and Proteins (journal article)
Schöneich, Christian
International Journal of Molecular Sciences, volume 23, issue 15, pages 8262- (2022).
10.3390/ijms23158262
Cited by (2) | Cite | Source
Near UV and Visible Light Photo-Degradation Mechanisms in Citrate Buffer: One-Electron Reduction of Peptide and Protein Disulfides promotes Oxidation and Cis/Trans Isomerization of Unsaturated Fatty Acids of Polysorbate 80 (journal article)
Prajapati, Indira | Subelzu, Natalia | Zhang, Yilue | Wu, Yaqi | Schöneich, Christian
Journal of Pharmaceutical Sciences, volume 111, issue 4, pages 991-1003 (2022).
10.1016/j.xphs.2022.01.026
Cited by (16) | Cite | Source
Oxidation and Deamidation of Monoclonal Antibody Products: Potential Impact on Stability, Biological Activity, and Efficacy (journal article)
Gupta, Surbhi | Jiskoot, Wim | Schöneich, Christian | Rathore, Anurag S.
Journal of Pharmaceutical Sciences, volume 111, issue 4, pages 903-918 (2022).
10.1016/j.xphs.2021.11.024
Cited by (62) | Cite | Source
Thiyl radicals: Formation, properties, and detection (book chapter)
In Redox Chemistry and Biology of Thiols
Schöneich, Christian
Elsevier (2022)
10.1016/B978-0-323-90219-9.00001-7
Cited by (6) | Cite | Source
Analysis of N15-rat growth hormone after incubation with rat subcutaneous tissue and immune cells using ultra-pressure chromatography-mass spectrometry (journal article)
Varkhede, Ninad | Björn-Hendrik, Peters | Moulder, K. Ryan | Gao, Philip | Schöneich, Christian | Forrest, M. Laird
Analytical Biochemistry, volume 634 (2021).
10.1016/j.ab.2021.114425
Cite | Source
Visible Light Degradation of a Monoclonal Antibody in a High-Concentration Formulation: Characterization of a Tryptophan-Derived Chromophoric Photo-product by Comparison to Photo-degradation of N -Acetyl- l -tryptophan Amide (journal article)
Prajapati, Indira | Larson, Nicholas R. | Choudhary, Sureshkumar | Kalonia, Cavan | Hudak, Suzanne | Esfandiary, Reza | Middaugh, C. Russell | Schöneich, Christian
Molecular Pharmaceutics, volume 18, issue 9, pages 3223-3234 (2021).
10.1021/acs.molpharmaceut.1c00043
Cited by (2) | Cite | Source