Jane Owens

ScholarGPS® ID: 58094380972906

Affiliation

Pfizer Inc., New York, United States

Affiliation History

Field

Life Sciences

Discipline

Genetics

Top Specialties

Skeletal Muscle | Muscular Dystrophy

Metrics Summary

Publication Count

Predicted Citations

502

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Evaluation of an AAV9-mini-dystrophin gene therapy candidate in a rat model of Duchenne muscular dystrophy (journal article) Le Guiner, Caroline \| Xiao, Xiao \| Larcher, Thibaut \| Lafoux, Aude \| Huchet, Corinne \| Toumaniantz, Gilles \| Adjali, Oumeya \| Anegon, Ignacio \| Remy, Séverine \| Grieger, Josh \| ... \| Samulski, R. Jude Molecular Therapy - Methods & Clinical Development, volume 30 (2023). 10.1016/j.omtm.2023.05.017 Cited by (1) \| Cite \| Source
CRISPR-mediated correction of skeletal muscle Ca2+ handling in a novel DMD patient-derived pluripotent stem cell model (journal article) Morera, Cristina \| Kim, Jihee \| Paredes-Redondo, Amaia \| Nobles, Muriel \| Rybin, Denis \| Moccia, Robert \| Kowala, Anna \| Meng, Jinhong \| Garren, Seth \| Liu, Pentao \| ... \| Lin, Yung-Yao Neuromuscular Disorders, volume 32, issue 11-12, pages 908-922 (2022). 10.1016/j.nmd.2022.10.007 Cited by (1) \| Cite \| Source
DUX4 expression activates JNK and p38 MAP kinases in myoblasts (journal article) Brennan, Christopher M. \| Hill, Abby S. \| St. Andre, Michael \| Li, Xianfeng \| Madeti, Vijaya \| Breitkopf, Susanne \| Garren, Seth \| Xue, Liang \| Gilbert, Tamara \| Hadjipanayis, Angela \| ... \| Christoforou, Nicolas Disease Models & Mechanisms, volume 15, issue 11 (2022). 10.1242/dmm.049516 Cited by (5) \| Cite \| Source
Dystrophin and mini-dystrophin quantification by mass spectrometry in skeletal muscle for gene therapy development in Duchenne muscular dystrophy (journal article) Farrokhi, Vahid \| Walsh, Jason \| Palandra, Joe \| Brodfuehrer, Joanne \| Caiazzo, Teresa \| Owens, Jane \| Binks, Michael \| Neelakantan, Srividya \| Yong, Florence \| Dua, Pinky \| ... \| Neubert, Hendrik Gene Therapy, volume 29, issue 10-11, pages 608-615 (2022). 10.1038/s41434-021-00300-7 Cited by (11) \| Cite \| Source
p38 MAPKs — roles in skeletal muscle physiology, disease mechanisms, and as potential therapeutic targets (journal article) Brennan, Christopher M. \| Emerson, Charles P. \| Owens, Jane \| Christoforou, Nicolas JCI Insight, volume 6, issue 12 (2021). 10.1172/jci.insight.149915 Cited by (40) \| Cite \| Source
Myostatin inhibition promotes fast fibre hypertrophy but causes loss of AMP‐activated protein kinase signalling and poor exercise tolerance in a model of limb‐girdle muscular dystrophy R1/2A (journal article) Kramerova, Irina \| Marinov, Masha \| Owens, Jane \| Lee, Se‐Jin \| Becerra, Diana \| Spencer, Melissa J. The Journal of Physiology, volume 598, issue 18, pages 3927-3939 (2020). 10.1113/JP279943 Cited by (6) \| Cite \| Source
Report of a TREAT-NMD/World Duchenne Organisation Meeting on Dystrophin Quantification Methodology (journal article) Aartsma-Rus, Annemieke \| Morgan, Jennifer \| Lonkar, Pallavi \| Neubert, Hendrik \| Owens, Jane \| Binks, Michael \| Montolio, Marisol \| Phadke, Rahul \| Datson, Nicole \| Van Deutekom, Judith \| ... \| Arechavala-Gomeza, Virginia Journal of Neuromuscular Diseases, volume 6, issue 1, pages 147-159 (2019). 10.3233/JND-180357 Cited by (46) \| Cite \| Source
A recombinant human IgG1 Fc multimer designed to mimic the active fraction of IVIG in autoimmunity (journal article) Zhang, Xiaoyu \| Owens, Jane \| Olsen, Henrik S. \| So, Edward \| Burch, Erin \| McCroskey, Mark C. \| Li, Xianfeng \| Weber, Gregory L. \| Bennett, Donald \| Rybin, Denis \| ... \| Strome, Scott E. JCI Insight, volume 4, issue 2 (2019). 10.1172/jci.insight.121905 Cited by (13) \| Cite \| Source
A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monk (journal article) St. Andre, Michael \| Johnson, Mark \| Bansal, Prashant N. \| Wellen, Jeremy \| Robertson, Andrew \| Opsahl, Alan \| Burch, Peter M. \| Bialek, Peter \| Morris, Carl \| Owens, Jane Skeletal Muscle, volume 7, issue 1 (2017). 10.1186/s13395-017-0141-y Cited by (72) \| Cite \| Source \| Open Access
A fully recombinant human IgG1 Fc multimer (GL-2045) inhibits complement-mediated cytotoxicity and induces iC3b (journal article) Zhou, Hua \| Olsen, Henrik \| So, Edward \| Mérigeon, Emmanuel \| Rybin, Denis \| Owens, Jane \| LaRosa, Gregory \| Block, David S. \| Strome, Scott E. \| Zhang, Xiaoyu Blood Advances, volume 1, issue 8, pages 504-515 (2017). 10.1182/bloodadvances.2016001917 Cited by (25) \| Cite \| Source \| Open Access
Understanding Lung Deposition of Alpha-1 Antitrypsin in Acute Experimental Mouse Lung Injury Model Using Fluorescence Microscopy (journal article) Wang, Mengmeng \| Zhan, Yutian \| Chen, Jianqing \| Rong, Haojing \| O’Neil, Shawn P. \| Ghosh, Brahma \| Nguyen, Vuong \| Owens, Jane \| Li, Xianfeng \| O’Hara, Denise M. International Journal of Molecular Imaging, volume 2016 (2016). 10.1155/2016/5768312 Cited by (2) \| Cite \| Source \| Open Access
Beyond CDR-grafting: Structure-guided humanization of framework and CDR regions of an anti-myostatin antibody (journal article) Apgar, James R. \| Mader, Michelle \| Agostinelli, Rita \| Benard, Susan \| Bialek, Peter \| Johnson, Mark \| Gao, Yijie \| Krebs, Mark \| Owens, Jane \| Parris, Kevin \| ... \| Tchistiakova, Lioudmila mAbs, volume 8, issue 7, pages 1302-1318 (2016). 10.1080/19420862.2016.1215786 Cited by (33) \| Cite \| Source \| Open Access
Safety, Pharmacokinetic, and Pharmacodynamic Evaluation After Single and Multiple Ascending Doses of a Novel Selective Androgen Receptor Modulator in Healthy Subjects (journal article) Bhattacharya, Indranil \| Tarabar, Sanela \| Liang, Yali \| Pradhan, Vivek \| Owens, Jane \| Oemar, Barry Clinical Therapeutics, volume 38, issue 6, pages 1401-1416 (2016). 10.1016/j.clinthera.2016.03.025 Cited by (21) \| Cite \| Source
Characterization of primary human skeletal muscle cells from multiple commercial sources (journal article) Owens, Jane \| Moreira, Karen \| Bain, Gerard In Vitro Cellular & Developmental Biology - Animal, volume 49, issue 9, pages 695-705 (2013). 10.1007/s11626-013-9655-8 Cited by (31) \| Cite \| Source \| Open Access
T.P.39 Building muscle with myostatin inhibitors (journal article) Bialek, P. \| Owens, J. \| St. Andre, M. \| Marsden, D. \| Denz, M. \| Yaworsky, P. \| Morris, C. Neuromuscular Disorders, volume 22, issue 9-10, pages 864- (2012). 10.1016/j.nmd.2012.06.204 Cite \| Source
Distinct protein degradation profiles are induced by different disuse models of skeletal muscle atrophy (journal article) Bialek, Peter \| Morris, Carl \| Parkington, Jascha \| St. Andre, Michael \| Owens, Jane \| Yaworsky, Paul \| Seeherman, Howard \| Jelinsky, Scott A. Physiological Genomics, volume 43, issue 19, pages 1075-1086 (2011). 10.1152/physiolgenomics.00247.2010 Cited by (46) \| Cite \| Source \| Open Access
Design and Evaluation of an Olfactometer for the Assessment of 3-Methylindole-Induced Hyposmia (journal article) Owens, J Fundamental and Applied Toxicology, volume 33, issue 1, pages 60-70 (1996). 10.1006/faat.1996.0143 Cited by (19) \| Cite \| Source