Quentin Lecocq

ScholarGPS® ID: 57560013984330

Affiliation

Vrije Universiteit Brussel, Brussels, Belgium

Affiliation History

Field

Life Sciences

Discipline

Biomedical Sciences

Top Specialties

Immune Checkpoint | Medical Imaging | Antibody

Metrics Summary

Publication Count

Predicted Citations

856

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Scrutiny of chimeric antigen receptor activation by the extracellular domain: experience with single domain antibodies targeting multiple myeloma cells highlights the need for case-by-case optimization (journal article) Hanssens, Heleen \| Meeus, Fien \| De Vlaeminck, Yannick \| Lecocq, Quentin \| Puttemans, Janik \| Debie, Pieterjan \| De Groof, Timo W. M. \| Goyvaerts, Cleo \| De Veirman, Kim \| Breckpot, Karine \| Devoogdt, Nick Frontiers in Immunology, volume 15 (2024). 10.3389/fimmu.2024.1389018 Cite \| Source
Phase I Study of [68 Ga]Ga-Anti-CD206-sdAb for PET/CT Assessment of Protumorigenic Macrophage Presence in Solid Tumors (MMR Phase I) (journal article) Gondry, Odrade \| Xavier, Catarina \| Raes, Laurens \| Heemskerk, Johannes \| Devoogdt, Nick \| Everaert, Hendrik \| Breckpot, Karine \| Lecocq, Quentin \| Decoster, Lore \| Fontaine, Christel \| ... \| Keyaerts, Marleen Journal of Nuclear Medicine, volume 64, issue 9, pages 1378-1384 (2023). 10.2967/jnumed.122.264853 Cited by (10) \| Cite \| Source
Targeted α-Therapy Using225 Ac Radiolabeled Single-Domain Antibodies Induces Antigen-Specific Immune Responses and Instills Immunomodulation Both Systemically and at the Tumor Microenvironment (journal article) Ertveldt, Thomas \| Krasniqi, Ahmet \| Ceuppens, Hannelore \| Puttemans, Janik \| Dekempeneer, Yana \| Jonghe, Kevin De \| Mey, Wout de \| Lecocq, Quentin \| Vlaeminck, Yannick De \| Awad, Robin Maximilian \| ... \| Breckpot, Karine Journal of Nuclear Medicine, volume 64, issue 5, pages 751-758 (2023). 10.2967/jnumed.122.264752 Cited by (8) \| Cite \| Source
Targeted Radionuclide Therapy with Low and High-Dose Lutetium-177–Labeled Single Domain Antibodies Induces Distinct Immune Signatures in a Mouse Melanoma Model (journal article) Ertveldt, Thomas \| De Beck, Lien \| De Ridder, Kirsten \| Locy, Hanne \| de Mey, Wout \| Goyvaerts, Cleo \| Lecocq, Quentin \| Ceuppens, Hannelore \| De Vlaeminck, Yannick \| Awad, Robin Maximilian \| ... \| Krasniqi, Ahmet Molecular Cancer Therapeutics, volume 21, issue 7, pages 1136-1148 (2022). 10.1158/1535-7163.MCT-21-0791 Cited by (8) \| Cite \| Source
Inhibiting Histone and DNA Methylation Improves Cancer Vaccination in an Experimental Model of Melanoma (journal article) De Beck, Lien \| Awad, Robin Maximilian \| Basso, Veronica \| Casares, Noelia \| De Ridder, Kirsten \| De Vlaeminck, Yannick \| Gnata, Alessandra \| Goyvaerts, Cleo \| Lecocq, Quentin \| San José-Enériz, Edurne \| ... \| Breckpot, Karine Frontiers in Immunology, volume 13 (2022). 10.3389/fimmu.2022.799636 Cited by (4) \| Cite \| Source
TNF-α-Secreting Lung Tumor-Infiltrated Monocytes Play a Pivotal Role During Anti-PD-L1 Immunotherapy (journal article) De Ridder, Kirsten \| Locy, Hanne \| Piccioni, Elisa \| Zuazo, Miren Ibarra \| Awad, Robin Maximilian \| Verhulst, Stefaan \| Van Bulck, Mathias \| De Vlaeminck, Yannick \| Lecocq, Quentin \| Reijmen, Eva \| ... \| Goyvaerts, Cleo Frontiers in Immunology, volume 13 (2022). 10.3389/fimmu.2022.811867 Cited by (8) \| Cite \| Source
168P Characterization of the lung tumor microenvironment upon anti-PD-L1 therapy reveals an ambiguous role for TNF-α (journal article) De Ridder, K. \| Locy, H. \| Piccioni, E. \| Ibarra Zuazo, M. \| Awad, R.M. \| Verhulst, S. \| van Bulck, M. \| De Vlaeminck, Y. \| Lecocq, Q. \| Reijmen, E. \| ... \| Goyvaerts, C. Annals of Oncology, volume 33 (2022). 10.1016/j.annonc.2022.02.200 Cite \| Source
Emerging applications of nanobodies in cancer therapy (book chapter) In New Antibody Formats Awad, Robin Maximilian \| Meeus, Fien \| Ceuppens, Hannelore \| Ertveldt, Thomas \| Hanssens, Heleen \| Lecocq, Quentin \| Mateusiak, Lukasz \| Zeven, Katty \| Valenta, Hana \| De Groof, Timo W.M. \| ... \| Breckpot, Karine Elsevier (2022) 10.1016/bs.ircmb.2022.03.010 Cited by (12) \| Cite \| Source
Evaluation of single domain antibodies as nuclear tracers for imaging of the immune checkpoint receptor human lymphocyte activation gene-3 in cancer (journal article) Lecocq, Q. \| Debie, P. \| Puttemans, J. \| Awad, R. M. \| De Beck, L. \| Ertveldt, T. \| De Vlaeminck, Y. \| Goyvaerts, C. \| Raes, G. \| Keyaerts, M. \| ... \| Devoogdt, N. EJNMMI Research, volume 11, issue 1 (2021). 10.1186/s13550-021-00857-9 Cited by (5) \| Cite \| Source
Single-Domain Antibody Nuclear Imaging Allows Noninvasive Quantification of LAG-3 Expression by Tumor-Infiltrating Leukocytes and Predicts Response of Immune Checkpoint Blockade (journal article) Lecocq, Quentin \| Awad, Robin Maximilian \| De Vlaeminck, Yannick \| de Mey, Wout \| Ertveldt, Thomas \| Goyvaerts, Cleo \| Raes, Geert \| Thielemans, Kris \| Keyaerts, Marleen \| Devoogdt, Nick \| Breckpot, Karine Journal of Nuclear Medicine, volume 62, issue 11, pages 1638-1644 (2021). 10.2967/jnumed.120.258871 Cited by (28) \| Cite \| Source
Formatting and gene-based delivery of a human PD-L1 single domain antibody for immune checkpoint blockade (journal article) Awad, Robin Maximilian \| Lecocq, Quentin \| Zeven, Katty \| Ertveldt, Thomas \| De Beck, Lien \| Ceuppens, Hannelore \| Broos, Katrijn \| De Vlaeminck, Yannick \| Goyvaerts, Cleo \| Verdonck, Magali \| ... \| Breckpot, Karine Molecular Therapy - Methods & Clinical Development, volume 22 (2021). 10.1016/j.omtm.2021.05.017 Cited by (11) \| Cite \| Source
Site-Specific Radiolabeling of a Human PD-L1 Nanobody via Maleimide–Cysteine Chemistry (journal article) Chigoho, Dora Mugoli \| Lecocq, Quentin \| Awad, Robin Maximilian \| Breckpot, Karine \| Devoogdt, Nick \| Keyaerts, Marleen \| Caveliers, Vicky \| Xavier, Catarina \| Bridoux, Jessica Pharmaceuticals, volume 14, issue 6, pages 550- (2021). 10.3390/ph14060550 Cited by (20) \| Cite \| Source
The Next-Generation Immune Checkpoint LAG-3 and Its Therapeutic Potential in Oncology: Third Time’s a Charm (journal article) Lecocq, Quentin \| Keyaerts, Marleen \| Devoogdt, Nick \| Breckpot, Karine International Journal of Molecular Sciences, volume 22, issue 1, pages 75- (2020). 10.3390/ijms22010075 Cited by (86) \| Cite \| Source
Targeting Neuropilin-1 with Nanobodies Reduces Colorectal Carcinoma Development (journal article) De Vlaeminck, Yannick \| Bonelli, Stefano \| Awad, Robin Maximilian \| Dewilde, Maarten \| Rizzolio, Sabrina \| Lecocq, Quentin \| Bolli, Evangelia \| Santos, Ana Rita \| Laoui, Damya \| Schoonooghe, Steve \| ... \| Van Ginderachter, Jo A. Cancers, volume 12, issue 12, pages 3582- (2020). 10.3390/cancers12123582 Cited by (21) \| Cite \| Source
Anti-Human PD-L1 Nanobody for Immuno-PET Imaging: Validation of a Conjugation Strategy for Clinical Translation (journal article) Bridoux, Jessica \| Broos, Katrijn \| Lecocq, Quentin \| Debie, Pieterjan \| Martin, Charlotte \| Ballet, Steven \| Raes, Geert \| Neyt, Sara \| Vanhove, Christian \| Breckpot, Karine \| ... \| Xavier, Catarina Biomolecules, volume 10, issue 10, pages 1388- (2020). 10.3390/biom10101388 Cited by (46) \| Cite \| Source
Therapeutic Efficacy of213 Bi-labeled sdAbs in a Preclinical Model of Ovarian Cancer (journal article) Dekempeneer, Yana \| Caveliers, Vicky \| Ooms, Maarten \| Maertens, Dominic \| Gysemans, Mireille \| Lahoutte, Tony \| Xavier, Catarina \| Lecocq, Quentin \| Maes, Ken \| Covens, Peter \| ... \| D’Huyvetter, Matthias Molecular Pharmaceutics, volume 17, issue 9, pages 3553-3566 (2020). 10.1021/acs.molpharmaceut.0c00580 Cited by (35) \| Cite \| Source
Preclinical Targeted α- and β−-Radionuclide Therapy in HER2-Positive Brain Metastasis Using Camelid Single-Domain Antibodies (journal article) Puttemans, Janik \| Dekempeneer, Yana \| Eersels, Jos L. \| Hanssens, Heleen \| Debie, Pieterjan \| Keyaerts, Marleen \| Windhorst, Albert D. \| van der Aa, Frank \| Lecocq, Quentin \| Breckpot, Karine \| ... \| D’Huyvetter, Matthias Cancers, volume 12, issue 4, pages 1017- (2020). 10.3390/cancers12041017 Cited by (46) \| Cite \| Source
Development of LAG-3 nanobodies as potent cancer imaging tracers (journal article) Lecocq, Q. \| Awad, R.M. \| Zeven, K. \| De Vlaeminck, Y. \| de Mey, W. \| Debie, P. \| Puttemans, J. \| Goyvaerts, C. \| Raes, G. \| Keyaerts, M. \| ... \| Breckpot, K. Annals of Oncology, volume 30 (2019). 10.1093/annonc/mdz447.032 Cite \| Source
Noninvasive Imaging of the Immune Checkpoint LAG-3 Using Nanobodies, from Development to Pre-Clinical Use (journal article) Lecocq, Quentin \| Zeven, Katty \| De Vlaeminck, Yannick \| Martens, Sandrina \| Massa, Sam \| Goyvaerts, Cleo \| Raes, Geert \| Keyaerts, Marleen \| Breckpot, Karine \| Devoogdt, Nick Biomolecules, volume 9, issue 10, pages 548- (2019). 10.3390/biom9100548 Cited by (44) \| Cite \| Source
Single-domain antibody fusion proteins can target and shuttle functional proteins into macrophage mannose receptor expressing macrophages (journal article) De Vlaeminck, Yannick \| Lecocq, Quentin \| Giron, Philippe \| Heirman, Carlo \| Geeraerts, Xenia \| Bolli, Evangelia \| Movahedi, Kiavash \| Massa, Sam \| Schoonooghe, Steve \| Thielemans, Kris \| ... \| Breckpot, Karine Journal of Controlled Release, volume 299 (2019). 10.1016/j.jconrel.2019.02.023 Cited by (17) \| Cite \| Source