Robert Webster

ScholarGPS® ID: 56529554082080

Affiliation

Pfizer Inc., New York, United States

Affiliation History

Field

Life Sciences

Discipline

Biology and Biological Sciences

Top Specialties

Medicinal Chemistry | Pharmacokinetics

Metrics Summary

Publication Count

Predicted Citations

1,278

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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A Physiologically‐Based Pharmacokinetic Model for the Prediction of “Half‐Life Extension” and “Catch and Release” Monoclonal Antibody Pharmacokinetics (journal article) Jones, Hannah M. \| Tolsma, John \| Zhang, Zhiwei \| Jasper, Paul \| Luo, Haobin \| Weber, Gregory L. \| Wright, Katherine \| Bard, Joel \| Bell, Robert \| Messing, Dean \| ... \| Webster, Robert CPT: Pharmacometrics & Systems Pharmacology, volume 9, issue 9, pages 534-541 (2020). 10.1002/psp4.12547 Cited by (13) \| Cite \| Source
A Physiologically‐Based Pharmacokinetic Model for the Prediction of Monoclonal Antibody Pharmacokinetics From In Vitro Data (journal article) Jones, Hannah M. \| Zhang, Zhiwei \| Jasper, Paul \| Luo, Haobin \| Avery, Lindsay B. \| King, Lindsay E. \| Neubert, Hendrik \| Barton, Hugh A. \| Betts, Alison M. \| Webster, Robert CPT: Pharmacometrics & Systems Pharmacology, volume 8, issue 10, pages 738-747 (2019). 10.1002/psp4.12461 Cited by (37) \| Cite \| Source
Preclinical Pharmacokinetics, Pharmacodynamics, Tissue Distribution, and Interspecies Scaling of Recombinant Human Coagulation Factor Xa I16L (journal article) Parng, Chuenlei \| Markiewicz, Victoria \| Chen, Jianqing \| Leary, Beth \| Duriga, Nicole \| Dyleski, Lisa \| Caiazzo, Teresa \| Bolt, Michael \| Joyce, Alison \| Gorovits, Boris \| ... \| Webster, Robert Journal of Pharmaceutical Sciences, volume 106, issue 8, pages 2136-2143 (2017). 10.1016/j.xphs.2017.03.035 Cited by (9) \| Cite \| Source
Non-benzimidazole containing inhibitors of respiratory syncytial virus (journal article) Pryde, David C. \| Tran, Thien-Duc \| Gardner, Iain \| Bright, Helen \| Stupple, Paul \| Galan, Sebastien \| Alsop, Liam \| Watson, Lesa \| Middleton, Donald S. \| Dayal, Satish \| ... \| Webster, Robert Bioorganic & Medicinal Chemistry Letters, volume 23, issue 3, pages 827-833 (2013). 10.1016/j.bmcl.2012.11.062 Cited by (8) \| Cite \| Source
Use of modelling and simulation techniques to support decision making on the progression of PF‐04878691, a TLR7 agonist being developed for hepatitis C (journal article) Jones, Hannah M. \| Chan, Phylinda L. S. \| van der Graaf, Piet H. \| Webster, Robert British Journal of Clinical Pharmacology, volume 73, issue 1, pages 77-92 (2012). 10.1111/j.1365-2125.2011.04047.x Cited by (10) \| Cite \| Source \| Open Access
An Imidazopiperidine Series of CCR5 Antagonists for the Treatment of HIV: The Discovery of N -{(1 S )-1-(3-Fluorophenyl)-3-[(3- endo )-3-(5-isobutyryl-2-methyl-4,5,6,7-tetrahydro-1 H -imidazo[4,5- c ]pyridin-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]propyl}acetam (journal article) Stupple, Paul A. \| Batchelor, David V. \| Corless, Martin \| Dorr, Patrick K. \| Ellis, David \| Fenwick, David R. \| Galan, Sébastien R. G. \| Jones, Rhys M. \| Mason, Helen J. \| Middleton, Donald S. \| ... \| Wood, Anthony Journal of Medicinal Chemistry, volume 54, issue 1, pages 67-77 (2011). 10.1021/jm100978n Cited by (35) \| Cite \| Source
Inhalation by Design: Novel Ultra-Long-Acting β2 -Adrenoreceptor Agonists for Inhaled Once-Daily Treatment of Asthma and Chronic Obstructive Pulmonary Disease That Utilize a Sulfonamide Agonist Headgroup (journal article) Glossop, Paul A. \| Lane, Charlotte A. L. \| Price, David A. \| Bunnage, Mark E. \| Lewthwaite, Russell A. \| James, Kim \| Brown, Alan D. \| Yeadon, Michael \| Perros-Huguet, Christelle \| Trevethick, Michael A. \| ... \| Spence, Fiona J. Journal of Medicinal Chemistry, volume 53, issue 18, pages 6640-6652 (2010). 10.1021/jm1005989 Cited by (72) \| Cite \| Source
ChemInform Abstract: Succinyl Hydroxamates as Potent and Selective Non‐peptidic Inhibitors of Procollagen C‐Proteinase: Design, Synthesis and Evaluation as Topically Applied, Dermal anti‐Scarring Agents. (journal article) Bailey, Simon \| Fish, Paul V. \| Billotte, Stephane \| Bordner, Jon \| Greiling, Doris \| James, Kim \| McElroy, Andrew \| Mills, James E. \| Reed, Charlotte \| Webster, Robert ChemInform, volume 40, issue 17 (2009). 10.1002/chin.200917220 Cite \| Source
Novel Indazole Non-Nucleoside Reverse Transcriptase Inhibitors Using Molecular Hybridization Based on Crystallographic Overlays (journal article) Jones, Lyn H. \| Allan, Gill \| Barba, Oscar \| Burt, Catherine \| Corbau, Romuald \| Dupont, Thomas \| Knöchel, Thorsten \| Irving, Steve \| Middleton, Donald S. \| Mowbray, Charles E. \| ... \| Phillips, Chris Journal of Medicinal Chemistry, volume 52, issue 4, pages 1219-1223 (2009). 10.1021/jm801322h Cited by (47) \| Cite \| Source
Determination of a potent urokinase-type plasminogen activator, UK-356,202, in plasma at pg/mL levels using column-switching HPLC and fluorescence detection (journal article) Bayliss, Mark A.J. \| Venn, Richard F. \| Edgington, Alan M. \| Webster, Robert \| Walker, Donald K. Journal of Chromatography B, volume 877, issue 3, pages 121-126 (2009). 10.1016/j.jchromb.2008.11.038 Cited by (4) \| Cite \| Source
Succinyl hydroxamates as potent and selective non-peptidic inhibitors of procollagen C-proteinase: Design, synthesis, and evaluation as topically applied, dermal anti-scarring agents (journal article) Bailey, Simon \| Fish, Paul V. \| Billotte, Stephane \| Bordner, Jon \| Greiling, Doris \| James, Kim \| McElroy, Andrew \| Mills, James E. \| Reed, Charlotte \| Webster, Robert Bioorganic & Medicinal Chemistry Letters, volume 18, issue 24, pages 6562-6567 (2008). 10.1016/j.bmcl.2008.10.036 Cited by (24) \| Cite \| Source
Potent and Selective Nonpeptidic Inhibitors of Procollagen C-Proteinase (journal article) Fish, Paul V. \| Allan, Gillian A. \| Bailey, Simon \| Blagg, Julian \| Butt, Richard \| Collis, Michael G. \| Greiling, Doris \| James, Kim \| Kendall, Jackie \| McElroy, Andrew \| ... \| Whitlock, Gavin A. Journal of Medicinal Chemistry, volume 50, issue 15, pages 3442-3456 (2007). 10.1021/jm061010z Cited by (64) \| Cite \| Source
Selective Urokinase-Type Plasminogen Activator Inhibitors. 4. 1-(7-Sulfonamidoisoquinolinyl)guanidines† (journal article) Fish, Paul V. \| Barber, Christopher G. \| Brown, David G. \| Butt, Richard \| Collis, Michael G. \| Dickinson, Roger P. \| Henry, Brian T. \| Horne, Valerie A. \| Huggins, John P. \| King, Elizabeth \| ... \| Webster, Robert Journal of Medicinal Chemistry, volume 50, issue 10, pages 2341-2351 (2007). 10.1021/jm061066t Cited by (52) \| Cite \| Source
Design of Ester Prodrugs to Enhance Oral Absorption of Poorly Permeable Compounds: Challenges to the Discovery Scientist (journal article) Beaumont, Kevin \| Webster, Robert \| Gardner, Iain \| Dack, Kevin Current Drug Metabolism, volume 4, issue 6, pages 461-485 (2003). 10.2174/1389200033489253 Cited by (449) \| Cite \| Source
Considerations in developing successful, population-based molecular screening and prevention of lung cancer (journal article) Mulshine, James L. \| De Luca, Luigi M. \| Dedrick, Robert L. \| Tockman, Melvyn S. \| Webster, Robert \| Placke, Michael E. Cancer, volume 89, issue S11, pages 2465-2467 (2000). 10.1002/1097-0142(20001201)89:11+<2465::AID-CNCR24>3.0.CO;2-6 Cited by (12) \| Cite \| Source
Kinetics of Aminoacyl-tRNA Synthetases Catalyzed ATP-PPi Exchange (book chapter) In Rna and Protein Synthesis Santi, Daniel V. \| Webster, Robert W. \| Cleland, W.W. Elsevier (1981) 10.1016/B978-0-12-504180-5.50031-6 Cite \| Source
In vivo inhibitors of Escherichia coli phenylalanyl-tRNA synthetase (journal article) Santi, Daniel V. \| Cunnion, Stephen O. \| Anderson, Robert T. \| Webster, Robert W. Journal of Medicinal Chemistry, volume 22, issue 10, pages 1260-1263 (1979). 10.1021/jm00196a021 Cited by (11) \| Cite \| Source
Phenylalanyl transfer ribonucleic acid synthetase from rat liver. Analysis of phenylalanine and adenosine 5'-triphosphate binding sites and comparison to the enzyme from Escherichia coli (journal article) Santi, Daniel V. \| Webster, Robert W. Journal of Medicinal Chemistry, volume 19, issue 11, pages 1276-1279 (1976). 10.1021/jm00233a003 Cited by (12) \| Cite \| Source
[49] Kinetics of aminoacyl-tRNA synthetases catalyzed ATP-PPi exchange (book chapter) In Nucleic Acids and Protein Synthesis Part E Santi, Daniel V. \| Webster, Robert W. \| Cleland, W.W. Elsevier (1974) 10.1016/0076-6879(74)29054-2 Cited by (23) \| Cite \| Source