Charles G. Glabe

ScholarGPS® ID: 56061871126294

Affiliation
University of California, Irvine, Irvine, United States
Affiliation History

Field
Life Sciences
Discipline
Molecular and Cell Biology
Top Specialties
Alzheimer's Disease | Peptide | Antibody | Dementia | Sperm | Amyloid Beta | Sea Urchin | Amyloid Precursor Protein | Monoclonal Antibody | Protein Precursor | Biophysics | Pathogenesis | Vaccination | Adhesion | Neurodegeneration
Metrics Summary
Publication Count
254
Predicted Citations
49,542
Predicted h-index
108
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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Microglial INPP5D limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimer's disease (journal article)
Castranio, Emilie L. | Hasel, Philip | Haure‐Mirande, Jean‐Vianney | Ramirez Jimenez, Angie V. | Hamilton, B. Wade | Kim, Rachel D. | Glabe, Charles G. | Wang, Minghui | Zhang, Bin | Gandy, Sam | ... | Ehrlich, Michelle E.
Alzheimer's & Dementia, volume 19, issue 6, pages 2239-2252 (2023).
10.1002/alz.12821
Cited by (25) | Cite | Source
Age-Related Oxidative Redox and Metabolic Changes Precede Intraneuronal Amyloid-β Accumulation and Plaque Deposition in a Transgenic Alzheimer’s Disease Mouse Model (journal article)
Pontrello, Crystal G. | McWhirt, Joshua M. | Glabe, Charles G. | Brewer, Gregory J.
Journal of Alzheimer's Disease, volume 90, issue 4, pages 1501-1521 (2022).
10.3233/JAD-220824
Cited by (5) | Cite | Source
Intracellular Injection of Brain Extracts from Alzheimer’s Disease Patients Triggers Unregulated Ca2+ Release from Intracellular Stores That Hinders Cellular Bioenergetics (journal article)
Pensalfini, Anna | Umar, Abdul Rahim | Glabe, Charles | Parker, Ian | Ullah, Ghanim | Demuro, Angelo
Cells, volume 11, issue 22, pages 3630- (2022).
10.3390/cells11223630
Cited by (1) | Cite | Source
Identification of amyloid antibodies for Alzheimer disease – immunotherapy (journal article)
Huwait, Etimad A. | Baghallab, Ibtisam M. | Glabe, Charles G. | Abulnaja, Khalid O. | Kumosani, Taha A. | Moselhy, Said S.
Archives of Physiology and Biochemistry, volume 128, issue 5, pages 1275-1282 (2022).
10.1080/13813455.2020.1767147
Cited by (2) | Cite | Source
Conformation-dependent anti-Aβ monoclonal antibody signatures of disease status and severity in urine of women with preeclampsia (journal article)
Valtanen, Rosa S. | Buhimschi, Catalin S. | Bahtiyar, Mert O. | Zhao, Guomao | Jing, Hongwu | Ackerman, William E. | Glabe, Charles G. | Buhimschi, Irina A.
Pregnancy Hypertension, volume 28 (2022).
10.1016/j.preghy.2022.01.007
Cited by (4) | Cite | Source
In vitro study of the mechanism of intraneuronal β- amyloid aggregation in Alzheimer’s disease (journal article)
Alsunusi, Shahad | Kumosani, Taha A. | Glabe, Charles G. | Huwait, Etimad A. | Moselhy, Said S.
Archives of Physiology and Biochemistry, volume 128, issue 3, pages 732-739 (2022).
10.1080/13813455.2020.1722707
Cited by (10) | Cite | Source
Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer’s disease (journal article)
Rimal, Suman | Li, Yu | Vartak, Rasika | Geng, Ji | Tantray, Ishaq | Li, Shuangxi | Huh, Sungun | Vogel, Hannes | Glabe, Charles | Grinberg, Lea T. | ... | Lu, Bingwei
Acta Neuropathologica Communications, volume 9, issue 1 (2021).
10.1186/s40478-021-01268-6
Cited by (28) | Cite | Source
An “epitomic” analysis of the specificity of conformation-dependent, anti-Aß amyloid monoclonal antibodies (journal article)
Reyes-Ruiz, Jorge Mauricio | Nakajima, Rie | Baghallab, Ibtisam | Goldschmidt, Luki | Sosna, Justyna | Mai Ho, Phuong Nguyen | Kumosani, Taha | Felgner, Philip L. | Glabe, Charles
Journal of Biological Chemistry, volume 296 (2021).
10.1074/jbc.RA120.015501
Cited by (6) | Cite | Source
Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease (journal article)
Abskharon, Romany | Seidler, Paul M. | Sawaya, Michael R. | Cascio, Duilio | Yang, Tianxiao P. | Philipp, Stephan | Williams, Christopher Kazu | Newell, Kathy L. | Ghetti, Bernardino | DeTure, Michael A. | ... | Eisenberg, David S.
Journal of Biological Chemistry, volume 295, issue 31, pages 10662-10676 (2020).
10.1074/jbc.RA120.013638
Cited by (17) | Cite | Source
“Dementia Biomarker Discovery Through Differential Immune Response Analysis” (journal article)
Gaxiola, Christian | Reyes, Jorge | Glabe, Charles
The FASEB Journal, volume 34, issue S1, pages 1-1 (2020).
10.1096/fasebj.2020.34.s1.07482
Cite | Source
Age-Related Intraneuronal Aggregation of Amyloid-β in Endosomes, Mitochondria, Autophagosomes, and Lysosomes (journal article)
Brewer, Gregory J. | Herrera, Robert A. | Philipp, Stephan | Sosna, Justyna | Reyes-Ruiz, Jorge Mauricio | Glabe, Charles G.
Journal of Alzheimer's Disease, volume 73, issue 1, pages 229-246 (2020).
10.3233/JAD-190835
Cited by (28) | Cite | Source
Intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus (journal article)
Forner, Stefania | Martini, Alessandra C. | Prieto, G. Aleph | Dang, Cindy T. | Rodriguez-Ortiz, Carlos J. | Reyes-Ruiz, Jorge Mauricio | Trujillo-Estrada, Laura | da Cunha, Celia | Andrews, Elizabeth J. | Phan, Jimmy | ... | LaFerla, Frank M.
Scientific Reports, volume 9, issue 1 (2019).
10.1038/s41598-019-52324-0
Cited by (11) | Cite | Source
Structure-based inhibitors of amyloid beta core suggest a common interface with tau (journal article)
Griner, Sarah L | Seidler, Paul | Bowler, Jeannette | Murray, Kevin A | Yang, Tianxiao Peter | Sahay, Shruti | Sawaya, Michael R | Cascio, Duilio | Rodriguez, Jose A | Philipp, Stephan | ... | Eisenberg, David S
eLife, volume 8 (2019).
10.7554/eLife.46924
Cited by (30) | Cite | Source
Apolipoprotein E/Amyloid-β Complex Accumulates in Alzheimer Disease Cortical Synapses via Apolipoprotein E Receptors and Is Enhanced by APOE4 (journal article)
Bilousova, Tina | Melnik, Mikhail | Miyoshi, Emily | Gonzalez, Bianca L. | Poon, Wayne W. | Vinters, Harry V. | Miller, Carol A. | Corrada, Maria M. | Kawas, Claudia | Hatami, Asa | ... | Gylys, Karen H.
The American Journal of Pathology, volume 189, issue 8, pages 1621-1636 (2019).
10.1016/j.ajpath.2019.04.010
Cited by (34) | Cite | Source
P4‐697: ATOMIC STRUCTURES OF A SINGLE CHAIN ANTIBODY THAT BINDS AND INHIBITS SEEDING BY TAU OLIGOMERS (journal article)
Abskharon, Romany | Seidler, Paul | Sawaya, Michael R. | Cascio, Duilio | Philipp, Stephan | Glabe, Charles G. | Eisenberg, David S.
Alzheimer's & Dementia, volume 15, issue 7S_Part_31 (2019).
10.1016/j.jalz.2019.09.061
Cite | Source
Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer’s disease (journal article)
Sosna, Justyna | Philipp, Stephan | Albay, Ricardo | Reyes-Ruiz, Jorge Mauricio | Baglietto-Vargas, David | LaFerla, Frank M. | Glabe, Charles G.
Molecular Neurodegeneration, volume 13, issue 1 (2018).
10.1186/s13024-018-0244-x
Cited by (227) | Cite | Source | Open Access
Epitomic Characterization of the Specificity of the Anti-Amyloid Aβ Monoclonal Antibodies 6E10 and 4G8 (journal article)
Baghallab, Ibtisam | Reyes-Ruiz, Jorge Mauricio | Abulnaja, Khalid | Huwait, Etimad | Glabe, Charles
Journal of Alzheimer's Disease, volume 66, issue 3, pages 1235-1244 (2018).
10.3233/JAD-180582
Cited by (47) | Cite | Source
Diagnostic and monitoring system for Huntington's disease (patent)
Potkin, Steven | Thompson, Leslie | Tan, Zhiqun | Glabe, Charles
Patent Number: 9989540 (2018)
Cite | Source
Desmin Phosphorylation Triggers Preamyloid Oligomers Formation and Myocyte Dysfunction in Acquired Heart Failure (journal article)
Rainer, Peter P. | Dong, Peihong | Sorge, Matteo | Fert-Bober, Justyna | Holewinski, Ronald J. | Wang, Yuchuan | Foss, Catherine A. | An, Steven S. | Baracca, Alessandra | Solaini, Giancarlo | ... | Agnetti, Giulio
Circulation Research, volume 122, issue 10 (2018).
10.1161/CIRCRESAHA.117.312082
Cited by (42) | Cite | Source | Open Access
ASSESSMENT OF POSSIBLE ASSOCIATION BETWEEN ANTIOXIDANT LEVELS AND APOE GENE POLYMORPHISM IN DEMENTED SAUDI POPULATION (journal article)
Alomari, Ohoud A. | Kumosani, Taha A. | Iyer, Archana P. | Huwait, EtimadA. | Bamaga, Mohammed S. | Salim, Naglaa M. | Glabe, Charles G.
Journal of Experimental Biology and Agricultural Sciences, volume 6, issue 1, pages 220-229 (2018).
10.18006/2018.6(1).220.229
Cite | Source | Open Access