David Santamaría

ScholarGPS® ID: 55763446623459

Affiliation

Institut National de la Santé et de la Recherche Médicale, France

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Cancer | Lung Cancer | Cell Cycle | Non-small-cell Lung Carcinoma

Metrics Summary

Publication Count

Predicted Citations

3,580

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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How far we have come targeting BRAF-mutant non-small cell lung cancer (NSCLC) (journal article) Tabbò, Fabrizio \| Pisano, Chiara \| Mazieres, Julien \| Mezquita, Laura \| Nadal, Ernest \| Planchard, David \| Pradines, Anne \| Santamaria, David \| Swalduz, Aurélie \| Ambrogio, Chiara \| ... \| Ortiz-Cuaran, Sandra Cancer Treatment Reviews, volume 103 (2022). 10.1016/j.ctrv.2021.102335 Cited by (19) \| Cite \| Source
Gene Expression Profiling as a Potential Tool for Precision Oncology in Non-Small Cell Lung Cancer (journal article) Hijazo-Pechero, Sara \| Alay, Ania \| Marín, Raúl \| Vilariño, Noelia \| Muñoz-Pinedo, Cristina \| Villanueva, Alberto \| Santamaría, David \| Nadal, Ernest \| Solé, Xavier Cancers, volume 13, issue 19, pages 4734- (2021). 10.3390/cancers13194734 Cited by (14) \| Cite \| Source
Targeting Infrequent Driver Alterations in Non-Small Cell Lung Cancer (journal article) Nokin, Marie-Julie \| Ambrogio, Chiara \| Nadal, Ernest \| Santamaria, David Trends in Cancer, volume 7, issue 5, pages 410-429 (2021). 10.1016/j.trecan.2020.11.005 Cited by (11) \| Cite \| Source
Tumor regression and resistance mechanisms upon CDK4 and RAF1 inactivation in KRAS/P53 mutant lung adenocarcinomas (journal article) Esteban-Burgos, Laura \| Wang, Haiyun \| Nieto, Patricia \| Zheng, Jie \| Blanco-Aparicio, Carmen \| Varela, Carmen \| Gómez-López, Gonzalo \| Fernández-García, Fernando \| Sanclemente, Manuel \| Guerra, Carmen \| ... \| Barbacid, Mariano Proceedings of the National Academy of Sciences, volume 117, issue 39, pages 24415-24426 (2020). 10.1073/pnas.2002520117 Cited by (16) \| Cite \| Source
Inhibition of DDR1 enhances in vivo chemosensitivity in KRAS-mutant lung adenocarcinoma (journal article) Nokin, Marie-Julie \| Darbo, Elodie \| Travert, Camille \| Drogat, Benjamin \| Lacouture, Aurélie \| San José, Sonia \| Cabrera, Nuria \| Turcq, Béatrice \| Prouzet-Mauleon, Valérie \| Falcone, Mattia \| ... \| Ambrogio, Chiara JCI Insight, volume 5, issue 15 (2020). 10.1172/jci.insight.137869 Cited by (19) \| Cite \| Source
Squamous differentiation requires G2/mitosis slippage to avoid apoptosis (journal article) Sanz-Gómez, Natalia \| de Pedro, Isabel \| Ortigosa, Beatriz \| Santamaría, David \| Malumbres, Marcos \| de Cárcer, Guillermo \| Gandarillas, Alberto Cell Death & Differentiation, volume 27, issue 8, pages 2451-2467 (2020). 10.1038/s41418-020-0515-2 Cited by (17) \| Cite \| Source
Meeting report – first discoidin domain receptors meeting (journal article) Auguste, Patrick \| Leitinger, Birgit \| Liard, Christelle \| Rocher, Virginie \| Azema, Laurent \| Saltel, Frederic \| Santamaria, David Journal of Cell Science, volume 133, issue 4 (2020). 10.1242/jcs.243824 Cited by (8) \| Cite \| Source
Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27 (journal article) García-Gutiérrez, Lucía \| Bretones, Gabriel \| Molina, Ester \| Arechaga, Ignacio \| Symonds, Catherine \| Acosta, Juan C. \| Blanco, Rosa \| Fernández, Adrián \| Alonso, Leticia \| Sicinski, Piotr \| ... \| León, Javier Scientific Reports, volume 9, issue 1 (2019). 10.1038/s41598-019-54917-1 Cited by (37) \| Cite \| Source
Molecular determinants of acquired resistance to BRAF inhibition in human lung cancer (journal article) Lucchesi, Carlo \| Drogat, Benjamin \| Santamaria, David \| Cousin, Sophie \| Italiano, Antoine Lung Cancer, volume 126 (2018). 10.1016/j.lungcan.2018.10.013 Cited by (3) \| Cite \| Source
A putative role for Discoidin Domain Receptor 1 in cancer chemoresistance (journal article) Ambrogio, Chiara \| Darbo, Elodie \| Lee, Sam W. \| Santamaría, David Cell Adhesion & Migration (2018). 10.1080/19336918.2018.1445954 Cited by (8) \| Cite \| Source
KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS (journal article) Ambrogio, Chiara \| Köhler, Jens \| Zhou, Zhi-Wei \| Wang, Haiyun \| Paranal, Raymond \| Li, Jiaqi \| Capelletti, Marzia \| Caffarra, Cristina \| Li, Shuai \| Lv, Qi \| ... \| Jänne, Pasi A. Cell, volume 172, issue 4, pages 857-868.e15 (2018). 10.1016/j.cell.2017.12.020 Cited by (198) \| Cite \| Source
Wild-type KRAS mediates growth inhibition and resistance to MEK inhibitors through dimerization with mutant KRAS in lung adenocarcinoma (journal article) Ambrogio, C. \| Kohler, J. \| Zhou, Z. \| Wang, H. \| Paranal, R. \| Capelletti, M. \| Caffarra, C. \| Li, S. \| Lv, Q. \| Santamaria, D. \| ... \| Jänne, P.A. Annals of Oncology, volume 28, issue suppl_5 (2017). 10.1093/annonc/mdx361 Cited by (3) \| Cite \| Source \| Open Access
A Braf kinase-inactive mutant induces lung adenocarcinoma (journal article) Nieto, Patricia \| Ambrogio, Chiara \| Esteban-Burgos, Laura \| Gómez-López, Gonzalo \| Blasco, María Teresa \| Yao, Zhan \| Marais, Richard \| Rosen, Neal \| Chiarle, Roberto \| Pisano, David G. \| ... \| Santamaría, David Nature, volume 548, issue 7666, pages 239-243 (2017). 10.1038/nature23297 Cited by (79) \| Cite \| Source \| Open Access
In vivo oncogenic conflict triggered by co-existing KRAS and EGFR activating mutations in lung adenocarcinoma (journal article) Ambrogio, C \| Barbacid, M \| Santamaría, D Oncogene, volume 36, issue 16, pages 2309-2318 (2017). 10.1038/onc.2016.385 Cited by (22) \| Cite \| Source
DDR1 and Notch: a multifaceted synergy (journal article) Ambrogio, Chiara \| Santamaría, David Translational cancer research, volume 5, issue 7 (2016). 10.21037/11335 Cite \| Source
DDR1 and Notch: a multifaceted synergy (journal article) Ambrogio, Chiara \| Santamaría, David Translational Cancer Research, volume 5, issue S7, pages S1551-S1553 (2016). 10.21037/tcr.2016.12.59 Cite \| Source
An essential pathway links FLT3-ITD, HCK and CDK6 in acute myeloid leukemia (journal article) Lopez, Sophie \| Voisset, Edwige \| Tisserand, Julie C. \| Mosca, Cyndie \| Prebet, Thomas \| Santamaria, David \| Dubreuil, Patrice \| De Sepulveda, Paulo Oncotarget, volume 7, issue 32 (2016). 10.18632/oncotarget.9965 Cited by (17) \| Cite \| Source \| Open Access
Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma (journal article) Ambrogio, Chiara \| Gómez-López, Gonzalo \| Falcone, Mattia \| Vidal, August \| Nadal, Ernest \| Crosetto, Nicola \| Blasco, Rafael B \| Fernández-Marcos, Pablo J \| Sánchez-Céspedes, Montserrat \| Ren, Xiaomei \| ... \| Barbacid, Mariano Nature Medicine, volume 22, issue 3, pages 270-277 (2016). 10.1038/nm.4041 Cited by (144) \| Cite \| Source
KRAS-driven lung adenocarcinoma: combined DDR1/Notch inhibition as an effective therapy (journal article) Ambrogio, Chiara \| Nadal, Ernest \| Villanueva, Alberto \| Gómez-López, Gonzalo \| Cash, Timothy P. \| Barbacid, Mariano \| Santamaría, David ESMO Open, volume 1, issue 5, pages e000076- (2016). 10.1136/esmoopen-2016-000076 Cited by (18) \| Cite \| Source \| Open Access
Functional Reprogramming of Polyploidization in Megakaryocytes (journal article) Trakala, Marianna \| Rodríguez-Acebes, Sara \| Maroto, María \| Symonds, Catherine E. \| Santamaría, David \| Ortega, Sagrario \| Barbacid, Mariano \| Méndez, Juan \| Malumbres, Marcos Developmental Cell, volume 32, issue 2, pages 155-167 (2015). 10.1016/j.devcel.2014.12.015 Cited by (44) \| Cite \| Source \| Open Access