Charles A. Dinarello | Scholar Profiles and Rankings

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Interleukin-1 Receptor Antagonism Abrogates Acute Pressure Overload-Induced Murine Heart Failure (journal article) Javan, Hadi \| Li, Ling \| Schaaf, Christin L. \| Lee, Young Sook \| Salama, Mohamed E. \| Dinarello, Charles A. \| Selzman, Craig H. The Annals of Thoracic Surgery, volume 114, issue 1, pages 98-107 (2022). 10.1016/j.athoracsur.2021.07.044 Cited by (1) \| Cite \| Source
Interleukin-38 in Health and Disease (journal article) de Graaf, Dennis M. \| Teufel, Lisa U. \| Joosten, Leo A.B. \| Dinarello, Charles A. Cytokine, volume 152 (2022). 10.1016/j.cyto.2022.155824 Cited by (3) \| Cite \| Source
The NLRP3 inflammasome inhibitor, OLT1177® , ameliorates experimental allergic asthma in mice (journal article) Lunding, Lars P. \| Skouras, Damaris B. \| Vock, Christina \| Dinarello, Charles A. \| Wegmann, Michael Allergy, volume 77, issue 3, pages 1035-1038 (2022). 10.1111/all.15164 Cited by (5) \| Cite \| Source
IL‐37 regulates allergic inflammation by counterbalancing pro‐inflammatory IL‐1 and IL‐33 (journal article) Schröder, Alexandra \| Lunding, Lars P. \| Zissler, Ulrich M. \| Vock, Christina \| Webering, Sina \| Ehlers, Johanna C. \| Orinska, Zane \| Chaker, Adam \| Schmidt‐Weber, Carsten B. \| Lang, Niklas J. \| ... \| Wegmann, Michael Allergy, volume 77, issue 3, pages 856-869 (2022). 10.1111/all.15072 Cited by (9) \| Cite \| Source
IL-1 family cytokines as drivers and inhibitors of trained immunity (journal article) Teufel, Lisa U. \| Arts, Rob J.W. \| Netea, Mihai G. \| Dinarello, Charles A. \| Joosten, Leo A.B. Cytokine, volume 150 (2022). 10.1016/j.cyto.2021.155773 Cited by (12) \| Cite \| Source
Inhibition of the NLRP3 inflammasome by OLT1177 induces functional protection and myelin preservation after spinal cord injury (journal article) Amo-Aparicio, Jesus \| Garcia-Garcia, Joana \| Puigdomenech, Maria \| Francos-Quijorna, Isaac \| Skouras, Damaris B. \| Dinarello, Charles A. \| Lopez-Vales, Ruben Experimental Neurology, volume 347 (2022). 10.1016/j.expneurol.2021.113889 Cited by (3) \| Cite \| Source
Urate-induced epigenetic modifications in myeloid cells (journal article) Badii, M. \| Gaal, O. I. \| Cleophas, M. C. \| Klück, V. \| Davar, R. \| Habibi, E. \| Keating, S. T. \| Novakovic, B. \| Helsen, M. M. \| Dalbeth, N. \| ... \| Joosten, L. A. B. Arthritis Research & Therapy, volume 23, issue 1 (2021). 10.1186/s13075-021-02580-1 Cited by (6) \| Cite \| Source
Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses (journal article) van Deuren, Rosanne C. \| Arts, Peer \| Cavalli, Giulio \| Jaeger, Martin \| Steehouwer, Marloes \| van de Vorst, Maartje \| Gilissen, Christian \| Joosten, Leo A. B. \| Dinarello, Charles A. \| Mhlanga, Musa M. \| ... \| Hoischen, Alexander Genome Medicine, volume 13, issue 1 (2021). 10.1186/s13073-021-00907-w Cited by (5) \| Cite \| Source
IL-38 prevents induction of trained immunity by inhibition of mTOR signaling (journal article) de Graaf, Dennis M \| Teufel, Lisa U \| van de Veerdonk, Frank L \| Joosten, Leo A B \| Netea, Mihai G \| Dinarello, Charles A \| Arts, Rob J W Journal of Leukocyte Biology, volume 110, issue 5, pages 907-915 (2021). 10.1002/JLB.3A0220-143RRR Cited by (11) \| Cite \| Source
Tumor NLRP3-Derived IL-1β Drives the IL-6/STAT3 Axis Resulting in Sustained MDSC-Mediated Immunosuppression (journal article) Tengesdal, Isak W. \| Dinarello, Alberto \| Powers, Nicholas E. \| Burchill, Matthew A. \| Joosten, Leo A. B. \| Marchetti, Carlo \| Dinarello, Charles A. Frontiers in Immunology, volume 12 (2021). 10.3389/fimmu.2021.661323 Cited by (15) \| Cite \| Source
Single-cell RNA-seq reveals a critical role of novel pro-inflammatory EndMT in mediating adverse remodeling in coronary artery–on–a–chip (journal article) Zhao, Peng \| Yao, Qingzhou \| Zhang, Pei-Jian \| The, Erlinda \| Zhai, Yufeng \| Ao, Lihua \| Jarrett, Michael J. \| Dinarello, Charles A. \| Fullerton, David A. \| Meng, Xianzhong Science Advances, volume 7, issue 34 (2021). 10.1126/sciadv.abg1694 Cited by (9) \| Cite \| Source
Interleukins in cancer: from biology to therapy (journal article) Briukhovetska, Daria \| Dörr, Janina \| Endres, Stefan \| Libby, Peter \| Dinarello, Charles A. \| Kobold, Sebastian Nature Reviews Cancer, volume 21, issue 8, pages 481-499 (2021). 10.1038/s41568-021-00363-z Cited by (120) \| Cite \| Source
Reduced CXCL1 production by endogenous IL-37 expressing dendritic cells does not affect T cell activation (journal article) Kouwenberg, M. \| Pulskens, W. P. C. \| Diepeveen, L. \| Bakker-van Bebber, M. \| Dinarello, C. A. \| Netea, M. G. \| Hilbrands, L. B. \| van der Vlag, J. PLOS ONE, volume 16, issue 5, pages e0251809- (2021). 10.1371/journal.pone.0251809 Cite \| Source
Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells (journal article) van der Heijden, Wouter A. \| Van de Wijer, Lisa \| Keramati, Farid \| Trypsteen, Wim \| Rutsaert, Sofie \| Horst, Rob ter \| Jaeger, Martin \| Koenen, Hans J.P.M. \| Stunnenberg, Hendrik G. \| Joosten, Irma \| ... \| de Mast, Quirijn JCI Insight, volume 6, issue 7 (2021). 10.1172/jci.insight.145928 Cited by (19) \| Cite \| Source
The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity (journal article) Cavalli, Giulio \| Tengesdal, Isak W. \| Gresnigt, Mark \| Nemkov, Travis \| Arts, Rob J.W. \| Domínguez-Andrés, Jorge \| Molteni, Raffaella \| Stefanoni, Davide \| Cantoni, Eleonora \| Cassina, Laura \| ... \| Dinarello, Charles A. Cell Reports, volume 35, issue 1, pages 108955- (2021). 10.1016/j.celrep.2021.108955 Cited by (18) \| Cite \| Source
Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion (journal article) Tengesdal, Isak W. \| Menon, Dinoop R. \| Osborne, Douglas G. \| Neff, Charles P. \| Powers, Nicholas E. \| Gamboni, Fabia \| Mauro, Adolfo G. \| D’Alessandro, Angelo \| Stefanoni, Davide \| Henen, Morkos A. \| ... \| Marchetti, Carlo Proceedings of the National Academy of Sciences, volume 118, issue 10 (2021). 10.1073/pnas.2000915118 Cited by (42) \| Cite \| Source
Modulation of Liver Inflammation and Fibrosis by Interleukin-37 (journal article) Mountford, Steffeni \| Effenberger, Maria \| Noll-Puchta, Heidi \| Griessmair, Lucas \| Ringleb, Andrea \| Haas, Sonja \| Denk, Gerald \| Reiter, Florian P. \| Mayr, Doris \| Dinarello, Charles A. \| ... \| Bufler, Philip Frontiers in Immunology, volume 12 (2021). 10.3389/fimmu.2021.603649 Cited by (13) \| Cite \| Source
Alpha-1 antitrypsin governs alcohol-related liver disease in mice and humans (journal article) Grander, Christoph \| Schaefer, Benedikt \| Schwärzler, Julian \| Grabherr, Felix \| de Graaf, Dennis M \| Enrich, Barbara \| Oberhuber, Georg \| Mayr, Lisa \| Sangineto, Moris \| Jaschke, Nikolai \| ... \| Tilg, Herbert Gut, volume 70, issue 3, pages 585-594 (2021). 10.1136/gutjnl-2020-321375 Cited by (2) \| Cite \| Source
Interleukin 1α: a comprehensive review on the role of IL-1α in the pathogenesis and treatment of autoimmune and inflammatory diseases (journal article) Cavalli, Giulio \| Colafrancesco, Serena \| Emmi, Giacomo \| Imazio, Massimo \| Lopalco, Giuseppe \| Maggio, Maria Cristina \| Sota, Jurgen \| Dinarello, Charles A. Autoimmunity Reviews, volume 20, issue 3, pages 102763- (2021). 10.1016/j.autrev.2021.102763 Cited by (66) \| Cite \| Source
IL‐18 and infections: Is there a role for targeted therapies? (journal article) Vecchié, Alessandra \| Bonaventura, Aldo \| Toldo, Stefano \| Dagna, Lorenzo \| Dinarello, Charles A. \| Abbate, Antonio Journal of Cellular Physiology, volume 236, issue 3, pages 1638-1657 (2021). 10.1002/jcp.30008 Cited by (41) \| Cite \| Source

Title	Investigators	Year	Cost	Agency
Pathogenesis of Fever in Man	Dinarello, Charles Anthony	2020	$388,750	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Pathogenesis of Fever in Man	Dinarello, Charles Anthony	2019	$388,750	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Molecular Mechanisms of Cytokine Induced Insulin Resistance	Dinarello, Charles Anthony \| LI, Suzhao \| Shen, Jingshi	2018	$228,632	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Pathogenesis of Fever in Man	Dinarello, Charles Anthony	2018	$388,750	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Molecular Mechanisms of Cytokine Induced Insulin Resistance	Dinarello, Charles Anthony \| LI, Suzhao \| Shen, Jingshi	2017	$203,768	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Pathogenesis of Fever in Man	Dinarello, Charles Anthony	2016	$311,000	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Pathogenesis of Fever in Humans	Dinarello, Charles Anthony	2014	$365,186	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Pathogenesis of Fever in Humans	Dinarello, Charles Anthony	2013	$343,275	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Pathogenesis of Fever in Humans	Dinarello, Charles Anthony	2012	$365,186	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Pathogenesis of Fever in Humans	Dinarello, Charles Anthony	2011	$365,186	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Pathogenesis of Fever in Humans	Dinarello, Charles Anthony	2010	$368,875	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Yeast-based HTS Assay Technologies for Proteases	Dinarello, Charles Anthony	2009	$137,805	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Pathogenesis of Fever in Humans	Dinarello, Charles Anthony	2008	$363,389	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Pathogenesis of Fever in Humans	Dinarello, Charles Anthony	2007	$358,134	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Heterogeneous Neutrophil Responses in Acute Lung Injury	Dinarello, Charles Anthony	2006	$1,559,247	NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
Pathogenesis of Fever in Humans	Dinarello, Charles Anthony	2006	$369,038	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Role of Interleukin-18 in Acute Lung Injury	Dinarello, Charles Anthony	2005	$252,187	NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
Heterogeneous Neutrophil Responses in Acute Lung Injury	Dinarello, Charles Anthony	2005	$1,513,126	NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
Pathogenesis of Fever in Humans	Dinarello, Charles Anthony	2005	$378,125	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Pathogenesis of Fever in Humans	Dinarello, Charles Anthony	2004	$377,138	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Pathogenesis of Fever in Humans	Dinarello, Charles Anthony	2003	$373,760	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Role of Interleukin-18 in Acute Lung Injury	Dinarello, Charles Anthony	2002	$237,381	NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
PATHOGENESIS OF FEVER IN HUMANS	Dinarello, Charles Anthony	2002	$464,351	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
PATHOGENESIS OF FEVER IN HUMANS	Dinarello, Charles Anthony	2001	$450,827	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
PATHOGENESIS OF FEVER IN HUMANS	Dinarello, Charles Anthony	2000	$437,695	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
PATHOGENESIS OF FEVER IN HUMANS	Dinarello, Charles Anthony	1999	$424,945	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
PATHOGENESIS OF FEVER IN HUMANS	Dinarello, Charles Anthony	1998	$112,942	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
PATHOGENESIS OF FEVER IN HUMANS	Dinarello, Charles Anthony	1998	$340,414	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
PATHOGENESIS OF FEVER IN HUMANS	Dinarello, Charles Anthony	1997	$447,253	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
PATHOGENESIS OF FEVER IN HUMANS	Dinarello, Charles Anthony	1996	$430,743	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
PATHOGENESIS OF FEVER IN HUMANS	Dinarello, Charles Anthony	1995	$450,206	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
PATHOGENESIS OF FEVER IN HUMANS	Dinarello, Charles Anthony	1994	$432,892	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
PATHOGENESIS OF FEVER IN HUMANS	Dinarello, Charles Anthony	1993	$422,380	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
PATHOGENENESIS OF FEVER IN HUMANS	Dinarello, Charles Anthony	1992	$304,610	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
PATHOGENENESIS OF FEVER IN HUMANS	Dinarello, Charles Anthony	1991	$294,877	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
PATHOGENESIS OF FEVER IN HUMANS	Dinarello, Charles Anthony	1990	$283,572	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
PATHOGENESIS OF FEVER IN HUMANS	Dinarello, Charles Anthony	1989	$0	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
PATHOGENENESIS OF FEVER IN HUMANS	Dinarello, Charles Anthony	1988	$299,137	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
PATHOGENESIS OF FEVER IN HUMANS	Dinarello, Charles Anthony	1987	$210,717	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
PATHOGENESIS OF FEVER IN HUMANS	Dinarello, Charles Anthony	1986	$228,127	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
PATHOGENESIS OF FEVER IN HUMANS	Dinarello, Charles Anthony	1985	$180,531	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES