Margaret Solon

ScholarGPS® ID: 50320852468721

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Medicine

Discipline

Pathology

Top Specialties

Asthma | Thorax | Inflammation | Allergy

Metrics Summary

Publication Count

Predicted Citations

2,004

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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ZBP1 and TRIF trigger lethal necroptosis in mice lacking caspase-8 and TNFR1 (journal article) Solon, Margaret \| Ge, Nianfeng \| Hambro, Shannon \| Haller, Susan \| Jiang, Jian \| Baca, Miriam \| Preston, Jessica \| Maltzman, Allie \| Wickliffe, Katherine E. \| Liang, Yuxin \| ... \| Webster, Joshua D. Cell Death & Differentiation, volume 31, issue 5, pages 672-682 (2024). 10.1038/s41418-024-01286-6 Cited by (4) \| Cite \| Source
T cell‐dependent bispecific antibodies alter organ‐specific endothelial cell–T cell interaction (journal article) Himmels, Patricia \| Nguyen, Thi Thu Thao \| Mitzner, Maresa Caunt \| Arrazate, Alfonso \| Yeung, Stacey \| Burton, Jeremy \| Clark, Robyn \| Totpal, Klara \| Jesudason, Raj \| Yang, Angela \| ... \| Ye, Weilan EMBO reports, volume 24, issue 3 (2023). 10.15252/embr.202255532 Cited by (3) \| Cite \| Source
Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α (journal article) Le Thomas, Adrien \| Ferri, Elena \| Marsters, Scot \| Harnoss, Jonathan M. \| Lawrence, David A. \| Zuazo-Gaztelu, Iratxe \| Modrusan, Zora \| Chan, Sara \| Solon, Margaret \| Chalouni, Cécile \| ... \| Ashkenazi, Avi Nature Communications, volume 12, issue 1 (2021). 10.1038/s41467-021-27597-7 Cited by (29) \| Cite \| Source
ADAR and hnRNPC deficiency synergize in activating endogenous dsRNA-induced type I IFN responses (journal article) Herzner, Anna-Maria \| Khan, Zia \| Van Nostrand, Eric L. \| Chan, Sara \| Cuellar, Trinna \| Chen, Ronald \| Pechuan-Jorge, Ximo \| Komuves, Laszlo \| Solon, Margaret \| Modrusan, Zora \| ... \| Albert, Matthew L. Journal of Experimental Medicine, volume 218, issue 9 (2021). 10.1084/jem.20201833 Cited by (11) \| Cite \| Source
Validating Immunohistochemistry Assay Specificity in Investigative Studies: Considerations for a Weight of Evidence Approach (journal article) Webster, Joshua D. \| Solon, Margaret \| Gibson-Corley, Katherine N. Veterinary Pathology, volume 58, issue 5, pages 829-840 (2021). 10.1177/0300985820960132 Cited by (11) \| Cite \| Source
A randomized, placebo‐controlled trial evaluating effects of lebrikizumab on airway eosinophilic inflammation and remodelling in uncontrolled asthma (CLAVIER) (journal article) Austin, Cary D. \| Gonzalez Edick, Melissa \| Ferrando, Ronald E. \| Solon, Margaret \| Baca, Miriam \| Mesh, Kathryn \| Bradding, Peter \| Gauvreau, Gail M. \| Sumino, Kaharu \| FitzGerald, J. Mark \| ... \| Woodruff, Prescott G. Clinical & Experimental Allergy, volume 50, issue 12, pages 1342-1351 (2020). 10.1111/cea.13731 Cited by (32) \| Cite \| Source
IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment (journal article) Harnoss, Jonathan M. \| Le Thomas, Adrien \| Reichelt, Mike \| Guttman, Ofer \| Wu, Thomas D. \| Marsters, Scot A. \| Shemorry, Anna \| Lawrence, David A. \| Kan, David \| Segal, Ehud \| ... \| Ashkenazi, Avi Cancer Research, volume 80, issue 11, pages 2368-2379 (2020). 10.1158/0008-5472.CAN-19-3108 Cited by (43) \| Cite \| Source
A Randomized, Placebo‐Controlled Trial Evaluating Effects of Lebrikizumab on Airway Eosinophilic Inflammation and Remodeling in Uncontrolled Asthma (CLAVIER) (journal article) Austin, Cary D. \| Edick, Melissa Gonzalez \| Ferrando, Ronald E. \| Solon, Margaret \| Baca, Miriam \| Mesh, Kathryn \| Bradding, Peter \| Gauvreau, Gail M. \| Sumino, Kaharu \| Fitzgerald, Mark \| ... \| Woodruff, Prescott G. The FASEB Journal, volume 34, issue S1, pages 1-1 (2020). 10.1096/fasebj.2020.34.s1.03747 Cite \| Source
Adaptive adipose tissue stromal plasticity in response to cold stress and antibody-based metabolic therapy (journal article) Chang, Joshua C. \| Durinck, Steffen \| Chen, Mark Z. \| Martinez-Martin, Nadia \| Zhang, Jingli A. \| Lehoux, Isabelle \| Li, Hong \| Lin, May \| Wu, Jiansheng \| Bainbridge, Travis W. \| ... \| Sonoda, Junichiro Scientific Reports, volume 9, issue 1 (2019). 10.1038/s41598-019-45354-1 Cited by (11) \| Cite \| Source
Detection of Necroptosis by Phospho-RIPK3 Immunohistochemical Labeling (book chapter) In Programmed Necrosis Webster, Joshua D. \| Solon, Margaret \| Haller, Susan \| Newton, Kim Springer New York (2018) 10.1007/978-1-4939-8754-2_15 Cited by (18) \| Cite \| Source
Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors (journal article) Merchant, Mark \| Moffat, John \| Schaefer, Gabriele \| Chan, Jocelyn \| Wang, Xi \| Orr, Christine \| Cheng, Jason \| Hunsaker, Thomas \| Shao, Lily \| Wang, Stephanie J. \| ... \| Junttila, Melissa R. PLOS ONE, volume 12, issue 10, pages e0185862- (2017). 10.1371/journal.pone.0185862 Cited by (62) \| Cite \| Source \| Open Access
Constitutive NOTCH3 Signaling Promotes the Growth of Basal Breast Cancers (journal article) Choy, Lisa \| Hagenbeek, Thijs J. \| Solon, Margaret \| French, Dorothy \| Finkle, David \| Shelton, Amy \| Venook, Rayna \| Brauer, Matthew J. \| Siebel, Christian W. Cancer Research, volume 77, issue 6, pages 1439-1452 (2017). 10.1158/0008-5472.CAN-16-1022 Cited by (69) \| Cite \| Source \| Open Access
RIPK1 inhibits ZBP1-driven necroptosis during development (journal article) Newton, Kim \| Wickliffe, Katherine E. \| Maltzman, Allie \| Dugger, Debra L. \| Strasser, Andreas \| Pham, Victoria C. \| Lill, Jennie R. \| Roose-Girma, Merone \| Warming, Søren \| Solon, Margaret \| ... \| Dixit, Vishva M. Nature, volume 540, issue 7631, pages 129-133 (2016). 10.1038/nature20559 Cited by (282) \| Cite \| Source
Preclinical Safety Profile of a Depleting Antibody against CRTh2 for Asthma: Well Tolerated Despite Unexpected CRTh2 Expression on Vascular Pericytes in the Central Nervous System and Gastric Mucosa (journal article) Rajapaksa, Kathila S. \| Huang, Tao \| Sharma, Neeraj \| Liu, Shannon \| Solon, Margaret \| Reyes, Arthur \| Paul, Sarah \| Yee, Angie \| Tao, Janet \| Chalasani, Sreedevi \| ... \| Austin, Cary D. Toxicological Sciences, volume 152, issue 1, pages 72-84 (2016). 10.1093/toxsci/kfw067 Cited by (6) \| Cite \| Source \| Open Access
Depletion of major pathogenic cells in asthma by targeting CRTh2 (journal article) Huang, Tao \| Hazen, Meredith \| Shang, Yonglei \| Zhou, Meijuan \| Wu, Xiumin \| Yan, Donghong \| Lin, Zhonghua \| Solon, Margaret \| Luis, Elizabeth \| Ngu, Hai \| ... \| Reif, Karin JCI Insight, volume 1, issue 7 (2016). 10.1172/jci.insight.86689 Cited by (27) \| Cite \| Source \| Open Access
Image Analysis-Based Approaches for Scoring Mouse Models of Colitis (journal article) Rogers, R. \| Eastham-Anderson, J. \| DeVoss, J. \| Lesch, J. \| Yan, D. \| Xu, M. \| Solon, M. \| Hotzel, K. \| Diehl, L. \| Webster, J. D. Veterinary Pathology, volume 53, issue 1, pages 200-210 (2016). 10.1177/0300985815579998 Cited by (12) \| Cite \| Source \| Open Access
387 Combination of the ERK inhibitor GDC-0994 with the MEK inhibitor cobimetinib significantly enhances anti-tumor activity in KRAS and BRAF mutant tumor models (journal article) Merchant, M. \| Chan, J. \| Orr, C. \| Cheng, J. \| Wang, X. \| Hunsaker, T. \| Wagle, M.C. \| Huang, S.A. \| Tremayne, J. \| Ngu, H. \| ... \| Junttila, M. European Journal of Cancer, volume 50 (2014). 10.1016/S0959-8049(14)70513-1 Cited by (6) \| Cite \| Source
Intelectin-1 Is a Prominent Protein Constituent of Pathologic Mucus Associated with Eosinophilic Airway Inflammation in Asthma (journal article) Kerr, Sheena C. \| Carrington, Stephen D. \| Oscarson, Stefan \| Gallagher, Mary E. \| Solon, Margaret \| Yuan, Shaopeng \| Ahn, Jacqueline N. \| Dougherty, Ryan H. \| Finkbeiner, Walter E. \| Peters, Michael C. \| Fahy, John V. American Journal of Respiratory and Critical Care Medicine, volume 189, issue 8, pages 1005-1007 (2014). 10.1164/rccm.201312-2220LE Cited by (36) \| Cite \| Source \| Open Access
Lactate Dehydrogenase B Is Required for the Growth of KRAS-Dependent Lung Adenocarcinomas (journal article) McCleland, Mark L. \| Adler, Adam S. \| Deming, Laura \| Cosino, Ely \| Lee, Leslie \| Blackwood, Elizabeth M. \| Solon, Margaret \| Tao, Janet \| Li, Li \| Shames, David \| ... \| Firestein, Ron Clinical Cancer Research, volume 19, issue 4, pages 773-784 (2013). 10.1158/1078-0432.CCR-12-2638 Cited by (97) \| Cite \| Source \| Open Access
Airway Epithelial miRNA Expression Is Altered in Asthma (journal article) Solberg, Owen D. \| Ostrin, Edwin J. \| Love, Michael I. \| Peng, Jeffrey C. \| Bhakta, Nirav R. \| Hou, Lydia \| Nguyen, Christine \| Solon, Margaret \| Nguyen, Cindy \| Barczak, Andrea J. \| ... \| Woodruff, Prescott G. American Journal of Respiratory and Critical Care Medicine, volume 186, issue 10, pages 965-974 (2012). 10.1164/rccm.201201-0027OC Cited by (203) \| Cite \| Source \| Open Access