Luigi Scotto

ScholarGPS® ID: 50177014400251

Affiliation

Columbia University, New York City, United States

Affiliation History

Field

Medicine

Discipline

Pathology

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

3,963

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Novel Therapeutic Strategies Exploiting the Unique Properties of Neuroendocrine Neoplasms (journal article) Safari, Maryam \| Scotto, Luigi \| Litman, Thomas \| Petrukhin, Lubov A. \| Zhu, Hu \| Shen, Min \| Robey, Robert W. \| Hall, Matthew D. \| Fojo, Tito \| Bates, Susan E. Cancers, volume 15, issue 20, pages 4960- (2023). 10.3390/cancers15204960 Cited by (1) \| Cite \| Source
Identifying the mechanistic differences between hypomethylating agents for the treatment of peripheral T cell lymphoma (journal article) Pal, I. \| Scotto, L. \| Sabzevari, A. \| Kinahan, C. \| Fox, T. E. \| Feith, D. J. \| Marchi, E. \| Loughran, T. P. \| O'Connor, O. A. Hematological Oncology, volume 41, issue S2, pages 313-314 (2023). 10.1002/hon.3164_220 Cite \| Source
Inhibition of casein kinase 1δ disrupts translation initiation and exerts potent antilymphoma activity (journal article) Pal, Ipsita \| Grilo, Andre M. Sardinha \| Gaspary, Alec \| Das Sharma, Sohani \| Scotto, Luigi \| O'Connor, Owen A. \| Jovanovic, Marko \| Deng, Changchun \| Berchowitz, Luke E. Blood Advances, volume 6, issue 14, pages 4157-4161 (2022). 10.1182/bloodadvances.2021006833 Cite \| Source
Characterization of newly established Pralatrexate-resistant cell lines and the mechanisms of resistance (journal article) Oiwa, Kana \| Hosono, Naoko \| Nishi, Rie \| Scotto, Luigi \| O’Connor, Owen A. \| Yamauchi, Takahiro BMC Cancer, volume 21, issue 1 (2021). 10.1186/s12885-021-08607-9 Cited by (4) \| Cite \| Source
Targeting the T-Cell Lymphoma Epigenome Induces Cell Death, Cancer Testes Antigens, Immune-Modulatory Signaling Pathways (journal article) Scotto, Luigi \| Kinahan, Cristina \| Douglass, Eugene \| Deng, Changchun \| Safari, Maryam \| Casadei, Beatrice \| Marchi, Enrica \| Lue, Jennifer K. \| Montanari, Francesca \| Falchi, Lorenzo \| ... \| O'Connor, Owen A. Molecular Cancer Therapeutics, volume 20, issue 8, pages 1422-1430 (2021). 10.1158/1535-7163.MCT-20-0377 Cited by (7) \| Cite \| Source
R-Loop–Mediated ssDNA Breaks Accumulate Following Short-Term Exposure to the HDAC Inhibitor Romidepsin (journal article) Safari, Maryam \| Litman, Thomas \| Robey, Robert W. \| Aguilera, Andrés \| Chakraborty, Arup R. \| Reinhold, William C. \| Basseville, Agnes \| Petrukhin, Lubov \| Scotto, Luigi \| O'Connor, Owen A. \| ... \| Bates, Susan E. Molecular Cancer Research, volume 19, issue 8, pages 1361-1374 (2021). 10.1158/1541-7786.MCR-20-0833 Cited by (14) \| Cite \| Source
Innovative Chemotherapy‐free Approaches for the Treatment of Peripheral T‐Cell Lymphoma (book chapter) In The Peripheral T‐Cell Lymphomas Marchi, Enrica \| Sawas, Ahmed \| Ma, Helen \| Scotto, Luigi \| Montanari, Francesca Wiley (2021) 10.1002/9781119671336.ch27 Cite \| Source
Combined oral 5-azacytidine and romidepsin are highly effective in patients with PTCL: a multicenter phase 2 study (journal article) Falchi, Lorenzo \| Ma, Helen \| Klein, Sandra \| Lue, Jennifer K. \| Montanari, Francesca \| Marchi, Enrica \| Deng, Changchun \| Kim, Hye A. \| Rada, Aishling \| Jacob, Alice T. \| ... \| O’Connor, Owen A. Blood, volume 137, issue 16, pages 2161-2170 (2021). 10.1182/blood.2020009004 Cited by (101) \| Cite \| Source
Cancer testis antigen expression across T‐cell lymphoma subtypes (journal article) Ma, Helen \| Soderquist, Craig R. \| Marchi, Enrica \| Scotto, Luigi \| Bhagat, Govind \| O'Connor, Owen A. Hematological Oncology, volume 38, issue 5, pages 827-830 (2020). 10.1002/hon.2785 Cited by (1) \| Cite \| Source
N-quinoline-benzenesulfonamide derivatives exert potent anti-lymphoma effect by targeting NF-κB (journal article) Kalac, Matko \| Mangone, Michael \| Rinderspacher, Alison \| Deng, Shi-Xian \| Scotto, Luigi \| Markson, Michael \| Bansal, Mukesh \| Califano, Andrea \| Landry, Donald W. \| O'Connor, Owen A. iScience, volume 23, issue 12, pages 101884- (2020). 10.1016/j.isci.2020.101884 Cited by (1) \| Cite \| Source
Generation of pralatrexate resistant T‐cell lymphoma lines reveals two patterns of acquired drug resistance that is overcome with epigenetic modifiers (journal article) Scotto, Luigi \| Kinahan, Cristina \| Casadei, Beatrice \| Mangone, Michael \| Douglass, Eugene \| Murty, Vundavalli V. \| Marchi, Enrica \| Ma, Helen \| George, Changchun \| Montanari, Francesca \| ... \| O'Connor, Owen A. Genes, Chromosomes and Cancer, volume 59, issue 11, pages 639-651 (2020). 10.1002/gcc.22884 Cited by (2) \| Cite \| Source
ATM inhibition overcomes resistance to histone deacetylase inhibitor due to p21 induction and cell cycle arrest (journal article) Scotto, Luigi \| Serrano, Xavier J. \| Zullo, Kelly \| Kinahan, Cristina \| Deng, Changchun \| Sawas, Ahmed \| Bates, Susan \| O’Connor, Owen A. Oncotarget, volume 11, issue 37, pages 3432-3442 (2020). 10.18632/oncotarget.27723 Cited by (6) \| Cite \| Source
Histone acetyltransferase activators and compositions and uses thereof (patent) O'Connor, Owen Anthony \| Amengual, Jennifer Effie \| Landry, Donald W. \| Arancio, Ottavio \| Scotto, Luigi \| Deng, Shixian \| Purgatorio, Rosa \| Fiorito, Jole Patent Number: 10653648 (2020) Cite \| Source
The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma (journal article) Kinahan, Cristina \| Mangone, Michael A. \| Scotto, Luigi \| Visentin, Michele \| Marchi, Enrica \| Cho, Hearn Jay \| O’Connor, Owen A. Oncotarget, volume 11, issue 18, pages 1576-1589 (2020). 10.18632/oncotarget.27516 Cited by (7) \| Cite \| Source
Oral 5-azacytidine and romidepsin exhibit marked activity in patients with PTCL: a multicenter phase 1 study (journal article) O’Connor, Owen A. \| Falchi, Lorenzo \| Lue, Jennifer K. \| Marchi, Enrica \| Kinahan, Cristina \| Sawas, Ahmed \| Deng, Changchun \| Montanari, Francesca \| Amengual, Jennifer E. \| Kim, Hye A. \| ... \| Scotto, Luigi Blood, volume 134, issue 17, pages 1395-1405 (2019). 10.1182/blood.2019001285 Cited by (100) \| Cite \| Source
UMBRALISIB AND CARFILZOMIB POTENTLY INHIBIT CAP DEPENDENT TRANSLATION IN LYMPHOMA (journal article) Pal, I. \| Sardinha, A.G. \| Scotto, L. \| Mundi, P.S. \| O'Connor, O.A. \| Deng, C. Hematological Oncology, volume 37, issue S2, pages 510-511 (2019). 10.1002/hon.193_2631 Cited by (1) \| Cite \| Source
IL-22–Independent Protection from Colitis in the Absence of Nkx2.3 Transcription Factor in Mice (journal article) Kellermayer, Zoltán \| Vojkovics, Dóra \| Dakah, Tareq Abu \| Bodó, Kornélia \| Botz, Bálint \| Helyes, Zsuzsanna \| Berta, Gergely \| Kajtár, Béla \| Schippers, Angela \| Wagner, Norbert \| ... \| Balogh, Péter The Journal of Immunology, volume 202, issue 6, pages 1833-1844 (2019). 10.4049/jimmunol.1801117 Cited by (7) \| Cite \| Source
Azacitidine and Romidepsin Synergize to Induce Expression of Cancer Testes Antigens (CTA) and Shift Peripheral T-Cell Lymphoma (PTCL) Cell Lines Toward a Th1-like Phenotype (journal article) Kinahan, Cristina \| Scotto, Luigi \| O'Connor, Owen A. Blood, volume 132, issue Supplement 1, pages 2845-2845 (2018). 10.1182/blood-2018-99-117344 Cite \| Source
Mechanisms of Acquired Drug Resistance to the HDAC6 Selective Inhibitor Ricolinostat Reveals Rational Drug-Drug Combination with Ibrutinib (journal article) Amengual, Jennifer E. \| Prabhu, Sathyen A. \| Lombardo, Maximilian \| Zullo, Kelly \| Johannet, Paul M. \| Gonzalez, Yulissa \| Scotto, Luigi \| Serrano, Xavier Jirau \| Wei, Ying \| Duong, Jimmy \| ... \| O'Connor, Owen A. Clinical Cancer Research, volume 23, issue 12, pages 3084-3096 (2017). 10.1158/1078-0432.CCR-16-2022 Cited by (19) \| Cite \| Source
AZACYTIDINE AND DECITABINE EXHIBIT DIFFERENTIAL EFFECTS ON CYTOTOXICITY AND METHYLATION AND EXHIBIT CLASS SYNERGY WITH HDACI IN MODELS OF PTCL (journal article) Scotto, L. \| Kinahan, C. \| Casadei, B. \| O'Connor, O.A. Hematological Oncology, volume 35, issue S2, pages 404-404 (2017). 10.1002/hon.2439_180 Cited by (4) \| Cite \| Source \| Open Access