Michael Honer

ScholarGPS® ID: 50027935924008

Affiliation

Roche Holding AG, Basel, Switzerland

Affiliation History

Field

Life Sciences

Discipline

Neurosciences

Top Specialties

Metrics Summary

Publication Count

105

Predicted Citations

6,982

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Identification of ( R )-[18 F]YH134 for Monoacylglycerol Lipase Neuroimaging and Exploration of Its Use for Central Nervous System and Peripheral Drug Development (journal article) He, Yingfang \| Krämer, Stefanie D. \| Grether, Uwe \| Wittwer, Matthias B. \| Collin, Ludovic \| Kuhn, Bernd \| Topp, Andreas \| Heer, Dominik \| O’Hara, Fionn \| Honer, Michael \| ... \| Mu, Linjing Journal of Nuclear Medicine, volume 65, issue 2, pages 300-305 (2024). 10.2967/jnumed.123.266426 Cite \| Source
Identification of (R)-[18F]YH134 as a promising reversible MAGL PET tracer and the impact of peripheral MAGL blockade on its brain uptake (journal article) Mu, Linjing \| He, Yingfang \| Krämer, Stefanie \| Grether, Uwe \| Wittwer, Matthias \| Honer, Michael \| Keller, Claudia \| Schibli, Roger \| Gobbi, Luca Nuclear Medicine and Biology, volume 126-127 (2023). 10.1016/j.nucmedbio.2023.108546 Cite \| Source
Evaluation of Tetrazine Tracers for Pretargeted Imaging within the Central Nervous System (journal article) Edelmann, Martin R. \| Bredack, Christoph \| Belli, Sara \| Mohr, Peter \| Imhoff, Marie-Paule \| Reggiani, Flore \| Kusznir, Eric A. \| Rufer, Arne C. \| Holt, Daniel P. \| Valentine, Heather \| ... \| Gobbi, Luca C. Bioconjugate Chemistry, volume 34, issue 10, pages 1882-1893 (2023). 10.1021/acs.bioconjchem.3c00385 Cited by (1) \| Cite \| Source
RO6807936 as a novel positron emission tomography (PET) radiotracer for in vitro and in vivo visualization and quantification of beta‐site amyloid precursor protein cleaving enzyme (BACE1) in the rodent and baboon brain (journal article) Honer, Michael \| Polara, Alessandra \| Kuwabara, Hiroto \| Jacobsen, Helmut \| Pähler, Axel \| Hartung, Thomas \| Caruso, Antonello \| Esterhazy, Daria \| Stoffel, Markus \| Dannals, Robert F. \| ... \| Gobbi, Luca C. Journal of Labelled Compounds and Radiopharmaceuticals, volume 66, issue 9, pages 222-236 (2023). 10.1002/jlcr.4025 Cite \| Source
[18F]RO948 tau positron emission tomography in genetic and sporadic frontotemporal dementia syndromes (journal article) Santillo, Alexander F. \| Leuzy, Antoine \| Honer, Michael \| Landqvist Waldö, Maria \| Tideman, Pontus \| Harper, Luke \| Ohlsson, Tomas \| Moes, Svenja \| Giannini, Lucia \| Jögi, Jonas \| ... \| Hansson, Oskar European Journal of Nuclear Medicine and Molecular Imaging, volume 50, issue 5, pages 1371-1383 (2023). 10.1007/s00259-022-06065-4 Cited by (1) \| Cite \| Source
Antibody-Based In Vivo Imaging of Central Nervous System Targets—Evaluation of a Pretargeting Approach Utilizing a TCO-Conjugated Brain Shuttle Antibody and Radiolabeled Tetrazines (journal article) Bredack, Christoph \| Edelmann, Martin R. \| Borroni, Edilio \| Gobbi, Luca C. \| Honer, Michael Pharmaceuticals, volume 15, issue 12, pages 1445- (2022). 10.3390/ph15121445 Cited by (7) \| Cite \| Source
Development of a novel reversible monoacylglycerol lipase PET tracer bearing a morpholine-3-one scaffold (journal article) He, Yingfang \| Grether, Uwe \| Taddio, Marco \| Keller, Claudia \| Honer, Michael \| Huber, Sywia \| Edelmann, Martin \| Krämer, Stefanie \| Schibli, Roger \| Gobbi, Luca \| Mu, Linjing Nuclear Medicine and Biology, volume 108-109 (2022). 10.1016/S0969-8051(22)00062-2 Cite \| Source
Discovery, synthesis and evaluation of novel reversible monoacylglycerol lipase radioligands bearing a morpholine-3-one scaffold (journal article) He, Yingfang \| Gobbi, Luca C. \| Herde, Adrienne Müller \| Rombach, Didier \| Ritter, Martin \| Kuhn, Bernd \| Wittwer, Matthias B. \| Heer, Dominik \| Hornsperger, Benoit \| Bell, Charles \| ... \| Mu, Linjing Nuclear Medicine and Biology, volume 108-109 (2022). 10.1016/j.nucmedbio.2022.02.002 Cited by (6) \| Cite \| Source
The Repertoire of Small-Molecule PET Probes for Neuroinflammation Imaging: Challenges and Opportunities beyond TSPO (journal article) Chen, Zhen \| Haider, Ahmed \| Chen, Jiahui \| Xiao, Zhiwei \| Gobbi, Luca \| Honer, Michael \| Grether, Uwe \| Arnold, Steven E. \| Josephson, Lee \| Liang, Steven H. Journal of Medicinal Chemistry, volume 64, issue 24, pages 17656-17689 (2021). 10.1021/acs.jmedchem.1c01571 Cited by (29) \| Cite \| Source
Basmisanil, a highly selective GABAA-α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man (journal article) Hipp, Joerg F. \| Knoflach, Frederic \| Comley, Robert \| Ballard, Theresa M. \| Honer, Michael \| Trube, Gerhard \| Gasser, Rodolfo \| Prinssen, Eric \| Wallace, Tanya L. \| Rothfuss, Andreas \| ... \| Hernandez, Maria-Clemencia Scientific Reports, volume 11, issue 1 (2021). 10.1038/s41598-021-87307-7 Cited by (13) \| Cite \| Source
Molecular and Functional Imaging in Central Nervous System Drug Development (book chapter) In Molecular Imaging Künnecke, Basil \| Honer, Michael \| Pagano, Gennaro \| Rudin, Markus Elsevier (2021) 10.1016/B978-0-12-816386-3.00084-3 Cite \| Source
Identification and Preclinical Development of a 2,5,6-Trisubstituted Fluorinated Pyridine Derivative as a Radioligand for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors (journal article) Haider, Ahmed \| Gobbi, Luca \| Kretz, Julian \| Ullmer, Christoph \| Brink, Andreas \| Honer, Michael \| Woltering, Thomas J. \| Muri, Dieter \| Iding, Hans \| Bürkler, Markus \| ... \| Ametamey, Simon M. Journal of Medicinal Chemistry, volume 63, issue 18, pages 10287-10306 (2020). 10.1021/acs.jmedchem.0c00778 Cited by (25) \| Cite \| Source
Structure–Activity Relationship Studies of Pyridine-Based Ligands and Identification of a Fluorinated Derivative for Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors (journal article) Haider, Ahmed \| Kretz, Julian \| Gobbi, Luca \| Ahmed, Hazem \| Atz, Kenneth \| Bürkler, Markus \| Bartelmus, Christian \| Fingerle, Jürgen \| Guba, Wolfgang \| Ullmer, Christoph \| ... \| Ametamey, Simon M. Journal of Medicinal Chemistry, volume 62, issue 24, pages 11165-11181 (2019). 10.1021/acs.jmedchem.9b01280 Cited by (21) \| Cite \| Source
18F-Flortaucipir in TDP-43 associated frontotemporal dementia (journal article) Smith, R. \| Santillo, A. F. \| Waldö, M. Landqvist \| Strandberg, O. \| Berron, D. \| Vestberg, S. \| van Westen, D. \| van Swieten, J. \| Honer, M. \| Hansson, O. Scientific Reports, volume 9, issue 1 (2019). 10.1038/s41598-019-42625-9 Cited by (26) \| Cite \| Source
Evaluation of18 F-RO-948 PET for Quantitative Assessment of Tau Accumulation in the Human Brain (journal article) Kuwabara, Hiroto \| Comley, Robert A. \| Borroni, Edilio \| Honer, Michael \| Kitmiller, Kelly \| Roberts, Joshua \| Gapasin, Lorena \| Mathur, Anil \| Klein, Gregory \| Wong, Dean F. Journal of Nuclear Medicine, volume 59, issue 12, pages 1877-1884 (2018). 10.2967/jnumed.118.214437 Cited by (58) \| Cite \| Source
Characterization of 3 Novel Tau Radiopharmaceuticals,11 C-RO-963,11 C-RO-643, and18 F-RO-948, in Healthy Controls and in Alzheimer Subjects (journal article) Wong, Dean F. \| Comley, Robert A. \| Kuwabara, Hiroto \| Rosenberg, Paul B. \| Resnick, Susan M. \| Ostrowitzki, Susanne \| Vozzi, Cristina \| Boess, Frank \| Oh, Esther \| Lyketsos, Constantine G. \| ... \| Borroni, Edilio Journal of Nuclear Medicine, volume 59, issue 12, pages 1869-1876 (2018). 10.2967/jnumed.118.209916 Cited by (81) \| Cite \| Source
2-phenyl or 2-hetaryl imidazol[1,2-a]pyridine derivatives (patent) Borroni, Edilio \| Gobbi, Luca \| Honer, Michael \| Knust, Henner \| Koerner, Matthias \| Muri, Dieter Patent Number: 10138234 (2018) Cite \| Source
mGluR5 Modulation of Behavioral and Epileptic Phenotypes in a Mouse Model of Tuberous Sclerosis Complex (journal article) Kelly, Elyza \| Schaeffer, Samantha M \| Dhamne, Sameer C \| Lipton, Jonathan O \| Lindemann, Lothar \| Honer, Michael \| Jaeschke, Georg \| Super, Chloe E \| Lammers, Stephen HT \| Modi, Meera E \| ... \| Sahin, Mustafa Neuropsychopharmacology, volume 43, issue 6, pages 1457-1465 (2018). 10.1038/npp.2017.295 Cited by (31) \| Cite \| Source
Preclinical Evaluation of18 F-RO6958948,11 C-RO6931643, and11 C-RO6924963 as Novel PET Radiotracers for Imaging Tau Aggregates in Alzheimer Disease (journal article) Honer, Michael \| Gobbi, Luca \| Knust, Henner \| Kuwabara, Hiroto \| Muri, Dieter \| Koerner, Matthias \| Valentine, Heather \| Dannals, Robert F. \| Wong, Dean F. \| Borroni, Edilio Journal of Nuclear Medicine, volume 59, issue 4, pages 675-681 (2018). 10.2967/jnumed.117.196741 Cited by (67) \| Cite \| Source
Identification of Three Novel Radiotracers for Imaging Aggregated Tau in Alzheimer’s Disease with Positron Emission Tomography (journal article) Gobbi, Luca C. \| Knust, Henner \| Körner, Matthias \| Honer, Michael \| Czech, Christian \| Belli, Sara \| Muri, Dieter \| Edelmann, Martin R. \| Hartung, Thomas \| Erbsmehl, Isabella \| ... \| Borroni, Edilio Journal of Medicinal Chemistry, volume 60, issue 17, pages 7350-7370 (2017). 10.1021/acs.jmedchem.7b00632 Cited by (71) \| Cite \| Source