Geoffrey T. Struble

ScholarGPS® ID: 49982427889481

Affiliation

Johnson & Johnson, New Brunswick, New Jersey, United States

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Medicinal Chemistry

Metrics Summary

Publication Count

Predicted Citations

555

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Novel LC/MS/MS and High-Throughput Mass Spectrometric Assays for Monoacylglycerol Acyltransferase Inhibitors (journal article) Qi, Jenson \| Masucci, John A. \| Lang, Wensheng \| Connelly, Margery A. \| Caldwell, Gary W. \| Petrounia, Ioanna \| Kirkpatrick, Jennifer \| Barnakov, Alexander N. \| Struble, Geoffrey \| Miller, Robyn \| ... \| Lee, Seunghun SLAS Discovery, volume 22, issue 4, pages 433-439 (2017). 10.1177/2472555217690101 Cited by (2) \| Cite \| Source
The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2 (journal article) Qi, Jenson \| Lang, Wensheng \| Geisler, John G. \| Wang, Ping \| Petrounia, Ioanna \| Mai, Selyna \| Smith, Charles \| Askari, Hossein \| Struble, Geoffrey T. \| Williams, Robyn \| ... \| Connelly, Margery A. Journal of Lipid Research, volume 53, issue 6, pages 1106-1116 (2012). 10.1194/jlr.M020156 Cited by (93) \| Cite \| Source \| Open Access
Electron Density Guided Fragment-Based Lead Discovery of Ketohexokinase Inhibitors (journal article) Gibbs, Alan C. \| Abad, Marta C. \| Zhang, Xuqing \| Tounge, Brett A. \| Lewandowski, Francis A. \| Struble, Geoffrey T. \| Sun, Weimei \| Sui, Zhihua \| Kuo, Lawrence C. Journal of Medicinal Chemistry, volume 53, issue 22, pages 7979-7991 (2010). 10.1021/jm100677s Cited by (35) \| Cite \| Source
4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors (journal article) Xu, Guozhang \| Abad, Marta C. \| Connolly, Peter J. \| Neeper, Michael P. \| Struble, Geoffrey T. \| Springer, Barry A. \| Emanuel, Stuart L. \| Pandey, Niranjan \| Gruninger, Robert H. \| Adams, Mary \| ... \| Middleton, Steven A. Bioorganic & Medicinal Chemistry Letters, volume 18, issue 16, pages 4615-4619 (2008). 10.1016/j.bmcl.2008.07.020 Cited by (63) \| Cite \| Source
Discovery of novel 4-amino-6-arylaminopyrimidine-5-carbaldehyde oximes as dual inhibitors of EGFR and ErbB-2 protein tyrosine kinases (journal article) Xu, Guozhang \| Searle, Lily Lee \| Hughes, Terry V. \| Beck, Amanda K. \| Connolly, Peter J. \| Abad, Marta C. \| Neeper, Michael P. \| Struble, Geoffrey T. \| Springer, Barry A. \| Emanuel, Stuart L. \| ... \| Greenberger, Lee M. Bioorganic & Medicinal Chemistry Letters, volume 18, issue 12, pages 3495-3499 (2008). 10.1016/j.bmcl.2008.05.024 Cited by (43) \| Cite \| Source
Enhancing Recombinant Protein Quality and Yield by Protein Stability Profiling (journal article) Mezzasalma, Tara M. \| Kranz, James K. \| Chan, Winnie \| Struble, Geoffrey T. \| Schalk-Hihi, Céline \| Deckman, Ingrid C. \| Springer, Barry A. \| Todd, Matthew J. SLAS Discovery, volume 12, issue 3, pages 418-428 (2007). 10.1177/1087057106297984 Cited by (85) \| Cite \| Source \| Open Access
Protein Engineering of the Colony-stimulating Factor-1 Receptor Kinase Domain for Structural Studies (journal article) Schalk-Hihi, Céline \| Ma, Hong-Chang \| Struble, Geoffrey T. \| Bayoumy, Shariff \| Williams, Robyn \| Devine, Eric \| Petrounia, Ioanna P. \| Mezzasalma, Tara \| Zeng, Lee \| Schubert, Carsten \| ... \| Deckman, Ingrid C. Journal of Biological Chemistry, volume 282, issue 6, pages 4085-4093 (2007). 10.1074/jbc.M608182200 Cited by (11) \| Cite \| Source \| Open Access
Crystal Structure of the Tyrosine Kinase Domain of Colony-stimulating Factor-1 Receptor (cFMS) in Complex with Two Inhibitors (journal article) Schubert, Carsten \| Schalk-Hihi, Céline \| Struble, Geoffrey T. \| Ma, Hong-Chang \| Petrounia, Ioanna P. \| Brandt, Benjamin \| Deckman, Ingrid C. \| Patch, Raymond J. \| Player, Mark R. \| Spurlino, John C. \| Springer, Barry A. Journal of Biological Chemistry, volume 282, issue 6, pages 4094-4101 (2007). 10.1074/jbc.M608183200 Cited by (57) \| Cite \| Source \| Open Access
Crystal structure of the c-fms kinase domain: applications and use of heterologous substitutions of kinase insert domains for crystallization (patent) Schubert, Carsten \| Springer, Barry A. \| Deckman, Ingrid C. \| Patch, Raymond J. \| Struble, Geoffrey T. \| Ma, Hongchang \| Schalk-Hihi, Celine \| Brandt, Benjamin M. \| Petrounia, Ioanna Patent Number: 20060094081 (2005) Cite \| Source