Sandra A. Bright

ScholarGPS® ID: 49867554367519

Affiliation
Trinity College Dublin, Dublin, Ireland
Affiliation History

Field
Life Sciences
Discipline
Biomedical Sciences
Top Specialties
Biosynthesis | DNA | Medicinal Chemistry | Medical Imaging
Metrics Summary
Publication Count
33
Predicted Citations
1,602
Predicted h-index
21
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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Tracking the cellular uptake and phototoxicity of Ru( ii )-polypyridyl-1,8-naphthalimide Tröger's base conjugates (journal article)
Bright, Sandra A. | Erby, MariaLuisa | Poynton, Fergus E. | Monteyne, Daniel | Pérez-Morga, David | Gunnlaugsson, Thorfinnur | Williams, D. Clive | Elmes, Robert B. P.
RSC Chemical Biology, volume 5, issue 4, pages 344-359 (2024).
10.1039/D3CB00206C
Cite | Source
Synthesis and Pro-Apoptotic Effects of Nitrovinylanthracenes and Related Compounds in Chronic Lymphocytic Leukaemia (CLL) and Burkitt’s Lymphoma (BL) (journal article)
Byrne, Andrew J. | Bright, Sandra A. | McKeown, James. P. | Bergin, Adam | Twamley, Brendan | McElligott, Anthony M. | Noorani, Sara | Kandwal, Shubhangi | Fayne, Darren | O’Boyle, Niamh M. | ... | Meegan, Mary J.
Molecules, volume 28, issue 24, pages 8095- (2023).
10.3390/molecules28248095
Cited by (1) | Cite | Source
Time-resolved infra-red studies of photo-excited porphyrins in the presence of nucleic acids and in HeLa tumour cells: insights into binding site and electron transfer dynamics (journal article)
Keane, Páraic M. | Zehe, Clara | Poynton, Fergus E. | Bright, Sandra A. | Estayalo-Adrián, Sandra | Devereux, Stephen J. | Donaldson, Paul M. | Sazanovich, Igor V. | Towrie, Michael | Botchway, Stanley W. | ... | Quinn, Susan J.
Physical Chemistry Chemical Physics, volume 24, issue 44, pages 27524-27531 (2022).
10.1039/D2CP04604K
Cited by (6) | Cite | Source
Effect of Alkyl Chain Length on the Photophysical, Photochemical, and Photobiological Properties of Ruthenium(II) Polypyridyl Complexes for Their Application as DNA-Targeting, Cellular-Imaging, and Light-Activated Therapeutic Agents (journal article)
Estalayo-Adrián, Sandra | Blasco, Salvador | Bright, Sandra A. | McManus, Gavin J. | Orellana, Guillermo | Williams, D. Clive | Kelly, John M. | Gunnlaugsson, Thorfinnur
ACS Applied Bio Materials, volume 4, issue 9, pages 6664-6681 (2021).
10.1021/acsabm.1c00284
Cited by (16) | Cite | Source
Water-soluble amphiphilic ruthenium( ii ) polypyridyl complexes as potential light-activated therapeutic agents (journal article)
Estalayo-Adrián, Sandra | Blasco, Salvador | Bright, Sandra A. | McManus, Gavin J. | Orellana, Guillermo | Williams, D. Clive | Kelly, John M. | Gunnlaugsson, Thorfinnur
Chemical Communications, volume 56, issue 65, pages 9332-9335 (2020).
10.1039/D0CC04397D
Cited by (18) | Cite | Source
4-Amino-1,8-naphthalimide based fluorescent photoinduced electron transfer (PET) pH sensors as liposomal cellular imaging agents: The effect of substituent patterns on PET directional quenching (journal article)
Martínez-Calvo, Miguel | Bright, Sandra A. | Veale, Emma B. | Henwood, Adam F. | Williams, D. Clive | Gunnlaugsson, Thorfinnur
Frontiers of Chemical Science and Engineering, volume 14, issue 1, pages 61-75 (2020).
10.1007/s11705-019-1862-8
Cited by (21) | Cite | Source
Design, Synthesis and Biochemical Evaluation of Novel Ethanoanthracenes and Related Compounds to Target Burkitt’s Lymphoma (journal article)
Byrne, Andrew J. | Bright, Sandra A. | McKeown, James P. | O’Brien, John E. | Twamley, Brendan | Fayne, Darren | Williams, D. Clive | Meegan, Mary J.
Pharmaceuticals, volume 13, issue 1, pages 16- (2020).
10.3390/ph13010016
Cited by (6) | Cite | Source
Synthesis and evaluation of antiproliferative microtubule-destabilising combretastatin A-4 piperazine conjugates (journal article)
O'Boyle, Niamh M. | Ana, Gloria | Kelly, Patrick M. | Nathwani, Seema M. | Noorani, Sara | Fayne, Darren | Bright, Sandra A. | Twamley, Brendan | Zisterer, Daniela M. | Meegan, Mary J.
Organic & Biomolecular Chemistry, volume 17, issue 25, pages 6184-6200 (2019).
10.1039/C9OB00558G
Cited by (18) | Cite | Source
Synthesis, Antiproliferative and Pro-Apoptotic Effects of Nitrostyrenes and Related Compounds in Burkitt's Lymphoma (journal article)
Byrne, Andrew J. | Bright, Sandra A. | Fayne, Darren | McKeown, James P. | McCabe, Thomas | Twamley, Brendan | Williams, Clive | Meegan, Mary J.
Medicinal Chemistry, volume 14, issue 2 (2018).
10.2174/1573406413666171002123907
Cited by (5) | Cite | Source
Novel Selective Estrogen Receptor Ligand Conjugates Incorporating Endoxifen-Combretastatin and Cyclofenil-Combretastatin Hybrid Scaffolds: Synthesis and Biochemical Evaluation (journal article)
Kelly, Patrick | Keely, Niall | Bright, Sandra | Yassin, Bassem | Ana, Gloria | Fayne, Darren | Zisterer, Daniela | Meegan, Mary
Molecules, volume 22, issue 9, pages 1440- (2017).
10.3390/molecules22091440
Cited by (26) | Cite | Source | Open Access
Luminescent Lanthanide Cyclen-Based Enzymatic Assay Capable of Diagnosing the Onset of Catheter-Associated Urinary Tract Infections Both in Solution and within Polymeric Hydrogels (journal article)
Surender, Esther M. | Bradberry, Samuel J. | Bright, Sandra A. | McCoy, Colin P. | Williams, D. Clive | Gunnlaugsson, Thorfinnur
Journal of the American Chemical Society, volume 139, issue 1, pages 381-388 (2017).
10.1021/jacs.6b11077
Cited by (75) | Cite | Source | Open Access
The development of ruthenium( ii ) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications (journal article)
Poynton, Fergus E. | Bright, Sandra A. | Blasco, Salvador | Williams, D. Clive | Kelly, John M. | Gunnlaugsson, Thorfinnur
Chemical Society Reviews, volume 46, issue 24, pages 7706-7756 (2017).
10.1039/C7CS00680B
Cited by (337) | Cite | Source
2-Nitroimidazole based fluorescent probes for nitroreductase; monitoring reductive stress in cellulo (journal article)
Ao, X. | Bright, S. A. | Taylor, N. C. | Elmes, R. B. P.
Organic & Biomolecular Chemistry, volume 15, issue 29, pages 6104-6108 (2017).
10.1039/C7OB01406F
Cited by (58) | Cite | Source
Synthesis, antiproliferative and pro-apoptotic activity of 2-phenylindoles (journal article)
Kelly, Patrick M. | Bright, Sandra A. | Fayne, Darren | Pollock, Jade K. | Zisterer, Daniela M. | Williams, D. Clive | Meegan, Mary J.
Bioorganic & Medicinal Chemistry, volume 24, issue 18, pages 4075-4099 (2016).
10.1016/j.bmc.2016.06.050
Cited by (19) | Cite | Source
The novel pyrrolo-1,5-benzoxazepine, PBOX-15, synergistically enhances the apoptotic efficacy of imatinib in gastrointestinal stromal tumours; suggested mechanism of action of PBOX-15 (journal article)
Kinsella, Paula | Greene, Lisa M. | Bright, Sandra A. | Pollock, Jade K. | Butini, Stefania | Campiani, Giuseppe | Bauer, Sebastian | Williams, D. Clive | Zisterer, Daniela M.
Investigational New Drugs, volume 34, issue 2, pages 159-167 (2016).
10.1007/s10637-016-0331-1
Cited by (4) | Cite | Source
Luminescent ruthenium polypyridyl complexes with extended ‘dppz’ like ligands as DNA targeting binders and cellular agents (journal article)
Poulsen, Bjørn C. | Estalayo-Adrián, Sandra | Blasco, Salvador | Bright, Sandra A. | Kelly, John M. | Williams, D. Clive | Gunnlaugsson, Thorfinnur
Dalton Transactions, volume 45, issue 45, pages 18208-18220 (2016).
10.1039/C6DT03792E
Cited by (36) | Cite | Source
Glycosidase activated release of fluorescent 1,8-naphthalimide probes for tumor cell imaging from glycosylated ‘pro-probes’ (journal article)
Calatrava-Pérez, Elena | Bright, Sandra A. | Achermann, Stefan | Moylan, Claire | Senge, Mathias O. | Veale, Emma B. | Williams, D. Clive | Gunnlaugsson, Thorfinnur | Scanlan, Eoin M.
Chemical Communications, volume 52, issue 89, pages 13086-13089 (2016).
10.1039/C6CC06451E
Cited by (70) | Cite | Source
Luminescent ruthenium polypyridyl complexes with extended 'dppz' like ligands as DNA targeting binders and cellular agents. (journal article)
Poulsen, Bjørn C | Estalayo-Adrián, Sandra | Blasco, Salvador | Bright, Sandra A | Kelly, John M | Williams, D Clive | Gunnlaugsson, Thorfinnur
Dalton transactions (Cambridge, England : 2003), volume 45, issue 45 (2016).
Cite
Glycosidase activated release of fluorescent 1,8-naphthalimide probes for tumor cell imaging from glycosylated 'pro-probes'. (journal article)
Calatrava-Pérez, Elena | Bright, Sandra A | Achermann, Stefan | Moylan, Claire | Senge, Mathias O | Veale, Emma B | Williams, D Clive | Gunnlaugsson, Thorfinnur | Scanlan, Eoin M
Chemical communications (Cambridge, England), volume 52, issue 89 (2016).
Cite
Unconventional Knoevenagel-type indoles: Synthesis and cell-based studies for the identification of pro-apoptotic agents (journal article)
Spallarossa, Andrea | Caneva, Chiara | Caviglia, Matteo | Alfei, Silvana | Butini, Stefania | Campiani, Giuseppe | Gemma, Sandra | Brindisi, Margherita | Zisterer, Daniela M. | Bright, Sandra A. | ... | Loddo, Roberta
European Journal of Medicinal Chemistry, volume 102 (2015).
10.1016/j.ejmech.2015.08.009
Cited by (10) | Cite | Source