Ioanna P. Petrounia

ScholarGPS® ID: 48991816979832

Affiliation

Johnson & Johnson, New Brunswick, New Jersey, United States

Affiliation History

Field

Life Sciences

Discipline

Biology and Biological Sciences

Top Specialties

Medicinal Chemistry | Protein Kinase Inhibitor | Chemical Synthesis

Metrics Summary

Publication Count

Predicted Citations

1,431

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Hit-to-lead optimization and discovery of a potent, and orally bioavailable G protein coupled receptor kinase 2 (GRK2) inhibitor (journal article) Xu, Guozhang \| Gaul, Michael D. \| Liu, Zhijie \| DesJarlais, Renee L. \| Qi, Jenson \| Wang, Weixue \| Krosky, Daniel \| Petrounia, Ioanna \| Milligan, Cynthia M. \| Hermans, An \| ... \| Spurlino, John C. Bioorganic & Medicinal Chemistry Letters, volume 30, issue 23, pages 127602- (2020). 10.1016/j.bmcl.2020.127602 Cited by (4) \| Cite \| Source
Novel LC/MS/MS and High-Throughput Mass Spectrometric Assays for Monoacylglycerol Acyltransferase Inhibitors (journal article) Qi, Jenson \| Masucci, John A. \| Lang, Wensheng \| Connelly, Margery A. \| Caldwell, Gary W. \| Petrounia, Ioanna \| Kirkpatrick, Jennifer \| Barnakov, Alexander N. \| Struble, Geoffrey \| Miller, Robyn \| ... \| Lee, Seunghun SLAS Discovery, volume 22, issue 4, pages 433-439 (2017). 10.1177/2472555217690101 Cited by (2) \| Cite \| Source
The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2 (journal article) Qi, Jenson \| Lang, Wensheng \| Geisler, John G. \| Wang, Ping \| Petrounia, Ioanna \| Mai, Selyna \| Smith, Charles \| Askari, Hossein \| Struble, Geoffrey T. \| Williams, Robyn \| ... \| Connelly, Margery A. Journal of Lipid Research, volume 53, issue 6, pages 1106-1116 (2012). 10.1194/jlr.M020156 Cited by (93) \| Cite \| Source \| Open Access
Inhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding Site (journal article) Maryanoff, Bruce E. \| O'Neill, John C. \| McComsey, David F. \| Yabut, Stephen C. \| Luci, Diane K. \| Jordan, Alfonzo D. \| Masucci, John A. \| Jones, William J. \| Abad, Marta C. \| Gibbs, Alan C. \| Petrounia, Ioanna ACS Medicinal Chemistry Letters, volume 2, issue 7, pages 538-543 (2011). 10.1021/ml200070g Cited by (32) \| Cite \| Source \| Open Access
Reducing ion channel activity in a series of 4-heterocyclic arylamide FMS inhibitors (journal article) Wilson, Kenneth J. \| Illig, Carl R. \| Chen, Jinsheng \| Wall, Mark J. \| Ballentine, Shelley K. \| DesJarlais, Renee L. \| Chen, Yanmin \| Schubert, Carsten \| Donatelli, Robert \| Petrounia, Ioanna \| ... \| Meegalla, Sanath K. Bioorganic & Medicinal Chemistry Letters, volume 20, issue 13, pages 3925-3929 (2010). 10.1016/j.bmcl.2010.05.013 Cited by (11) \| Cite \| Source
Design and synthesis of a pyrido[2,3-d]pyrimidin-5-one class of anti-inflammatory FMS inhibitors (journal article) Huang, Hui \| Hutta, Daniel A. \| Hu, Huaping \| DesJarlais, Renee L. \| Schubert, Carsten \| Petrounia, Ioanna P. \| Chaikin, Margery A. \| Manthey, Carl L. \| Player, Mark R. Bioorganic & Medicinal Chemistry Letters, volume 18, issue 7, pages 2355-2361 (2008). 10.1016/j.bmcl.2008.02.070 Cited by (46) \| Cite \| Source
Discovery of novel FMS kinase inhibitors as anti-inflammatory agents (journal article) Illig, Carl R. \| Chen, Jinsheng \| Wall, Mark J. \| Wilson, Kenneth J. \| Ballentine, Shelley K. \| Rudolph, M. Jonathan \| DesJarlais, Renee L. \| Chen, Yanmin \| Schubert, Carsten \| Petrounia, Ioanna \| ... \| Meegalla, Sanath K. Bioorganic & Medicinal Chemistry Letters, volume 18, issue 5, pages 1642-1648 (2008). 10.1016/j.bmcl.2008.01.059 Cited by (44) \| Cite \| Source
Synthesis and evaluation of novel 3,4,6-substituted 2-quinolones as FMS kinase inhibitors (journal article) Wall, Mark J. \| Chen, Jinsheng \| Meegalla, Sanath \| Ballentine, Shelley K. \| Wilson, Kenneth J. \| DesJarlais, Renee L. \| Schubert, Carsten \| Chaikin, Margery A. \| Crysler, Carl \| Petrounia, Ioanna P. \| ... \| Illig, Carl R. Bioorganic & Medicinal Chemistry Letters, volume 18, issue 6, pages 2097-2102 (2008). 10.1016/j.bmcl.2008.01.088 Cited by (47) \| Cite \| Source
Potent 2′-aminoanilide inhibitors of cFMS as potential anti-inflammatory agents (journal article) Patch, Raymond J. \| Brandt, Benjamin M. \| Asgari, Davoud \| Baindur, Nand \| Chadha, Naresh K. \| Georgiadis, Taxiarchis \| Cheung, Wing S. \| Petrounia, Ioanna P. \| Donatelli, Robert R. \| Chaikin, Margery A. \| Player, Mark R. Bioorganic & Medicinal Chemistry Letters, volume 17, issue 22, pages 6070-6074 (2007). 10.1016/j.bmcl.2007.09.057 Cited by (26) \| Cite \| Source
Glucose 6-oxidases (patent) Arnold, Frances H. \| Sun, Lian-Hong \| Petrounia, Ioanna P. Patent Number: 7220563 (2007) Cited by (1) \| Cite \| Source
Crystal Structure of the Tyrosine Kinase Domain of Colony-stimulating Factor-1 Receptor (cFMS) in Complex with Two Inhibitors (journal article) Schubert, Carsten \| Schalk-Hihi, Céline \| Struble, Geoffrey T. \| Ma, Hong-Chang \| Petrounia, Ioanna P. \| Brandt, Benjamin \| Deckman, Ingrid C. \| Patch, Raymond J. \| Player, Mark R. \| Spurlino, John C. \| Springer, Barry A. Journal of Biological Chemistry, volume 282, issue 6, pages 4094-4101 (2007). 10.1074/jbc.M608183200 Cited by (57) \| Cite \| Source \| Open Access
Protein Engineering of the Colony-stimulating Factor-1 Receptor Kinase Domain for Structural Studies (journal article) Schalk-Hihi, Céline \| Ma, Hong-Chang \| Struble, Geoffrey T. \| Bayoumy, Shariff \| Williams, Robyn \| Devine, Eric \| Petrounia, Ioanna P. \| Mezzasalma, Tara \| Zeng, Lee \| Schubert, Carsten \| ... \| Deckman, Ingrid C. Journal of Biological Chemistry, volume 282, issue 6, pages 4085-4093 (2007). 10.1074/jbc.M608182200 Cited by (11) \| Cite \| Source \| Open Access
The synthesis and SAR of 2-amino-pyrrolo[2,3-d]pyrimidines: A new class of Aurora-A kinase inhibitors (journal article) Moriarty, Kevin J. \| Koblish, Holly K. \| Garrabrant, Thomas \| Maisuria, Jahanvi \| Khalil, Ehab \| Ali, Farah \| Petrounia, Ioanna P. \| Crysler, Carl S. \| Maroney, Anna C. \| Johnson, Dana L. \| Galemmo, Robert A. Bioorganic & Medicinal Chemistry Letters, volume 16, issue 22, pages 5778-5783 (2006). 10.1016/j.bmcl.2006.08.080 Cited by (93) \| Cite \| Source
Directed evolution of galactose oxidase enzymes (patent) Arnold, Frances H. \| Petrounia, Ioanna P. \| Sun, Lianhong Patent Number: 7115403 (2006) Cited by (11) \| Cite \| Source
Directed evolution of oxidase enzymes (patent) Arnold, Frances H. \| Petrounia, Ioanna P. \| Sun, Lianhong Patent Number: 7098010 (2006) Cited by (10) \| Cite \| Source
Crystal structure of the c-fms kinase domain: applications and use of heterologous substitutions of kinase insert domains for crystallization (patent) Schubert, Carsten \| Springer, Barry A. \| Deckman, Ingrid C. \| Patch, Raymond J. \| Struble, Geoffrey T. \| Ma, Hongchang \| Schalk-Hihi, Celine \| Brandt, Benjamin M. \| Petrounia, Ioanna Patent Number: 20060094081 (2005) Cite \| Source
2-Hydroxy-4,6-diamino-[1,3,5]triazines: A Novel Class of VEGF-R2 (KDR) Tyrosine Kinase Inhibitors (journal article) Baindur, Nand \| Chadha, Naresh \| Brandt, Benjamin M. \| Asgari, Davoud \| Patch, Raymond J. \| Schalk-HiHi, Celine \| Carver, Theodore E. \| Petrounia, Ioanna P. \| Baumann, Christian A. \| Ott, Heidi \| ... \| Player, Mark R. Journal of Medicinal Chemistry, volume 48, issue 6, pages 1717-1720 (2005). 10.1021/jm049372z Cited by (52) \| Cite \| Source
Modification of Galactose Oxidase to Introduce Glucose 6-Oxidase Activity (journal article) Sun, Lianhong \| Bulter, Thomas \| Alcalde, Miguel \| Petrounia, Ioanna P. \| Arnold, Frances H. ChemBioChem, volume 3, issue 8, pages 781- (2002). 10.1002/1439-7633(20020802)3:8<781::AID-CBIC781>3.0.CO;2-8 Cited by (102) \| Cite \| Source
Expression and stabilization of galactose oxidase in Escherichia coli by directed evolution (journal article) Sun, Lianhong \| Petrounia, Ioanna P. \| Yagasaki, Makoto \| Bandara, Geethani \| Arnold, Frances H. Protein Engineering, Design and Selection, volume 14, issue 9, pages 699-704 (2001). 10.1093/protein/14.9.699 Cited by (111) \| Cite \| Source \| Open Access
Designed evolution of enzymatic properties (journal article) Petrounia, Ioanna P \| Arnold, Frances H Current Opinion in Biotechnology, volume 11, issue 4, pages 325-330 (2000). 10.1016/S0958-1669(00)00107-5 Cited by (165) \| Cite \| Source