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Zhen Gong

ScholarGPS® ID: 48930156556889

Affiliation

WuXi AppTec, China

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Medicinal Chemistry

Metrics Summary

Publication Count

9

Predicted Citations

291

Predicted h-index

8

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Discovery and Evaluation of Pyrazolo[3,4- d ]pyridazinone as a Potent and Orally Active Irreversible BTK Inhibitor (journal article) Zhang, Xuejun \| Sheng, Xijun \| Shen, Jie \| Zhang, Shoubo \| Sun, Wenjie \| Shen, Chunli \| Li, Yi \| Wang, Jun \| Lv, Huqiang \| Cui, Minghui \| ... \| Wu, Chengde ACS Medicinal Chemistry Letters, volume 11, issue 10, pages 1863-1868 (2020). 10.1021/acsmedchemlett.9b00395 Cited by (16) \| Cite \| Source
Discovery of a Novel Selective Dual Peroxisome Proliferator-Activated Receptor α/δ Agonist for the Treatment of Primary Biliary Cirrhosis (journal article) Jiang, Zhigan \| Liu, Xing \| Yuan, Zhiliang \| He, Haiying \| Wang, Jing \| Zhang, Xiao \| Gong, Zhen \| Hou, Lijuan \| Shen, Liang \| Guo, Fengxun \| ... \| Chen, Shuhui ACS Medicinal Chemistry Letters, volume 10, issue 7, pages 1068-1073 (2019). 10.1021/acsmedchemlett.9b00189 Cited by (5) \| Cite \| Source
Discovery of Pyridopyrimidinones as Potent and Orally Active Dual Inhibitors of PI3K/mTOR (journal article) Yu, Tao \| Li, Ning \| Wu, Chengde \| Guan, Amy \| Li, Yi \| Peng, Zhengang \| He, Miao \| Li, Jie \| Gong, Zhen \| Huang, Lei \| ... \| Chen, Shuhui ACS Medicinal Chemistry Letters, volume 9, issue 3, pages 256-261 (2018). 10.1021/acsmedchemlett.8b00002 Cited by (12) \| Cite \| Source
Compound Libraries: Recent Advances and Their Applications in Drug Discovery (journal article) Gong, Zhen \| Hu, Guoping \| Li, Qiang \| Liu, Zhiguo \| Wang, Fei \| Zhang, Xuejin \| Xiong, Jian \| Li, Peng \| Xu, Yan \| Ma, Rujian \| ... \| Li, Jian Current Drug Discovery Technologies, volume 14, issue 4 (2017). 10.2174/1570163814666170425155154 Cited by (26) \| Cite \| Source
Design, Synthesis, and Evaluation of Tetrahydropyrrolo[1,2- c ]pyrimidines as Capsid Assembly Inhibitors for HBV Treatment (journal article) Li, Xiaolin \| Zhou, Kai \| He, Haiying \| Zhou, Qiong \| Sun, Ya \| Hou, Lijuan \| Shen, Liang \| Wang, Xiaofei \| Zhou, Yuedong \| Gong, Zhen \| ... \| Chen, Shuhui ACS Medicinal Chemistry Letters, volume 8, issue 9, pages 969-974 (2017). 10.1021/acsmedchemlett.7b00288 Cited by (19) \| Cite \| Source
Epitope mapping reveals the binding mechanism of a functional antibody cross-reactive to both human and murine programmed death 1 (journal article) Li, Dong \| Xu, Jianqing \| Wang, Zhuozhi \| Gong, Zhen \| Liu, Jieying \| Zheng, Yong \| Li, Jian \| Li, Jing mAbs, volume 9, issue 4, pages 628-637 (2017). 10.1080/19420862.2017.1296612 Cited by (9) \| Cite \| Source \| Open Access
Intermolecular Sulfur···Oxygen Interactions: Theoretical and Statistical Investigations (journal article) Zhang, Xuejin \| Gong, Zhen \| Li, Jian \| Lu, Tao Journal of Chemical Information and Modeling, volume 55, issue 10, pages 2138-2153 (2015). 10.1021/acs.jcim.5b00177 Cited by (88) \| Cite \| Source
Minimization of drug–drug interaction risk and candidate selection in a natural product-based class of gamma-secretase modulators (journal article) Hubbs, Jed L. \| Fuller, Nathan O. \| Austin, Wesley F. \| Shen, Ruichao \| Ma, Jianguo \| Gong, Zhen \| Li, Jian \| McKee, Timothy D. \| Loureiro, Robyn M.B. \| Tate, Barbara \| ... \| Bronk, Brian S. Bioorganic & Medicinal Chemistry Letters, volume 25, issue 7, pages 1621-1626 (2015). 10.1016/j.bmcl.2015.01.051 Cited by (10) \| Cite \| Source
Crystal structure of Drosophila melanogaster tryptophan 2,3-dioxygenase reveals insights into substrate recognition and catalytic mechanism (journal article) Huang, Wei \| Gong, Zhen \| Li, Jian \| Ding, Jianping Journal of Structural Biology, volume 181, issue 3, pages 291-299 (2013). 10.1016/j.jsb.2013.01.002 Cited by (25) \| Cite \| Source