Lieven Meerpoel

ScholarGPS® ID: 47456797519698

Affiliation

Janssen Pharmaceutica

Affiliation History

Field

Medicine

Discipline

Oncology

Top Specialties

Metrics Summary

Publication Count

184

Predicted Citations

3,687

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Synthesis of Cyclopropyl Pinacol Boronic Esters from Dibromocyclopropanes (journal article) Neouchy, Zeina \| Hullaert, Jan \| Verhoeven, Jonas \| Meerpoel, Lieven \| Thuring, Jan-Willem \| Verniest, Guido \| Winne, Johan Synlett, volume 33, issue 08, pages 759-766 (2022). 10.1055/s-0037-1610794 Cited by (2) \| Cite \| Source
Stereodivergent Synthesis of Biologically Active Spironucleoside Scaffolds via Catalytic Cyclopropanation of 4- exo -Methylene Furanosides (journal article) Neouchy, Zeina \| Verhoeven, Jonas \| Kong, Hanchu \| Zhao, Yongbin \| Wang, Wenbin \| Brambilla, Marta \| Van Hecke, Kristof \| Meerpoel, Lieven \| Thuring, Jan Willem \| Verniest, Guido \| Winne, Johan The Journal of Organic Chemistry, volume 86, issue 23, pages 17344-17361 (2021). 10.1021/acs.joc.1c01611 Cited by (6) \| Cite \| Source
Regio- and Stereoselective Synthesis of C-4′ Spirocyclobutyl Ribofuranose Scaffolds and Their Use as Biologically Active Nucleoside Analogues (journal article) Jouffroy, Lucile \| Verhoeven, Jonas \| Brambilla, Marta \| Verniest, Guido \| Kong, Hanchu \| Zhao, Yongbin \| Wang, Wenbin \| Meerpoel, Lieven \| Thuring, Jan Willem \| Winne, Johan M. Organic Letters, volume 23, issue 22, pages 8828-8833 (2021). 10.1021/acs.orglett.1c03334 Cited by (6) \| Cite \| Source
Spirocyclic Thiohydantoin Antagonists of F877L and Wild-Type Androgen Receptor for Castration-Resistant Prostate Cancer (journal article) Zhang, Zhuming \| Connolly, Peter J. \| Trabalón Escolar, Luis \| Rocaboy, Christian \| Pande, Vineet \| Meerpoel, Lieven \| Lim, Heng-Keang \| Branch, Jonathan R. \| Ondrus, Janine \| Hickson, Ian \| ... \| Bignan, Gilles ACS Medicinal Chemistry Letters, volume 12, issue 8, pages 1245-1252 (2021). 10.1021/acsmedchemlett.1c00032 Cited by (3) \| Cite \| Source
Preparation of Novel 4′-Spirocyclopropyl Nucleoside Analogues (journal article) Verhoeven, Jonas \| Kong, Hanchu \| Zhao, Yongbin \| Wang, Wenbin \| Pande, Vineet \| Brambilla, Marta \| Van Hecke, Kristof \| Meerpoel, Lieven \| Thuring, Jan Willem \| Verniest, Guido Synlett, volume 32, issue 09, pages 892-896 (2021). 10.1055/a-1386-7194 Cited by (6) \| Cite \| Source
Discovery of JNJ-63576253, a Next-Generation Androgen Receptor Antagonist Active Against Wild-Type and Clinically Relevant Ligand Binding Domain Mutations in Metastatic Castration-Resistant Prostate Cancer (journal article) Branch, Jonathan R. \| Bush, Tammy L. \| Pande, Vineet \| Connolly, Peter J. \| Zhang, Zhuming \| Hickson, Ian \| Ondrus, Janine \| Jaensch, Steffen \| Bischoff, James R. \| Habineza, Georges \| ... \| Bignan, Gilles Molecular Cancer Therapeutics, volume 20, issue 5, pages 763-774 (2021). 10.1158/1535-7163.MCT-20-0510 Cited by (3) \| Cite \| Source
Discovery of JNJ-63576253: A Clinical Stage Androgen Receptor Antagonist for F877L Mutant and Wild-Type Castration-Resistant Prostate Cancer (mCRPC) (journal article) Zhang, Zhuming \| Connolly, Peter J. \| Lim, Heng Keang \| Pande, Vineet \| Meerpoel, Lieven \| Teleha, Christopher \| Branch, Jonathan R. \| Ondrus, Janine \| Hickson, Ian \| Bush, Tammy \| ... \| Bignan, Gilles Journal of Medicinal Chemistry, volume 64, issue 2, pages 909-924 (2021). 10.1021/acs.jmedchem.0c01563 Cited by (17) \| Cite \| Source
Synthesis and Reactivity of Spirocarbocycles as Scaffolds for Nucleoside Analogues (journal article) Verhoeven, Jonas \| Deraet, Xavier \| Pande, Vineet \| Sun, Weimei \| Alonso, Mercedes \| De Proft, Frank \| Meerpoel, Lieven \| Thuring, Jan Willem \| Verniest, Guido The Journal of Organic Chemistry, volume 85, issue 23, pages 14989-15005 (2020). 10.1021/acs.joc.0c01825 Cited by (2) \| Cite \| Source
A Chemical Probe for the Methyl Transferase PRMT5 with a Novel Binding Mode (journal article) Pande, Vineet \| Sun, Weimei \| Beke, Lijs \| Berthelot, Didier \| Brehmer, Dirk \| Brown, David \| Corbera, Jordi \| Irving, Steve \| Meerpoel, Lieven \| Nys, Thomas \| ... \| Thuring, Jan Willem ACS Medicinal Chemistry Letters, volume 11, issue 11, pages 2227-2231 (2020). 10.1021/acsmedchemlett.0c00355 Cited by (14) \| Cite \| Source
FEP+ calculations predict a stereochemical SAR switch for first-in-class indoline NIK inhibitors for multiple myeloma (journal article) Jacoby, Edgar \| Vlijmen, Herman Van \| Querolle, Olivier \| Stansfield, Ian \| Meerpoel, Lieven \| Versele, Matthias \| Hynd, George \| Attar, Ricardo Future Drug Discovery, volume 2, issue 3 (2020). 10.4155/fdd-2020-0004 Cited by (2) \| Cite \| Source
Pd(0)-Catalyzed Direct Inter- and Intramolecular C–H Functionalization of 4-Carboxyimidazoles (journal article) Frippiat, Steven \| Peresson, Antoine \| Perse, Thibaut \| Ramondenc, Yvan \| Schneider, Cédric \| Querolle, Olivier \| Angibaud, Patrick \| Poncelet, Virginie \| Meerpoel, Lieven \| Levacher, Vincent \| ... \| Hoarau, Christophe Synlett (2020). 10.1055/s-0040-1708003 Cited by (9) \| Cite \| Source
6-6 bicyclic aromatic ring substituted nucleoside analogues for use as PRMT5 inhibitors (patent) Wu, Tongfei \| Brehmer, Dirk \| Beke, Lijs \| Boeckx, An \| Diels, Gaston Stanislas Marcella \| Gilissen, Ronaldus Arnodus Hendrika Joseph \| Lawson, Edward Charles \| Pande, Vineet \| Paradé, Marcus Cornelis Bernardus Catharina \| Schepens, Wim Bert Griet \| ... \| Meerpoel, Lieven Patent Number: 10653711 (2020) Cited by (1) \| Cite \| Source
Organic glasses with tunable liquid-crystalline order through kinetic arrest of end-over-end rotation: the case of saperconazole (journal article) Chen, Zhenxuan \| Yu, Junguang \| Teerakapibal, Rattavut \| Meerpoel, Lieven \| Richert, Ranko \| Yu, Lian Soft Matter, volume 16, issue 8, pages 2025-2030 (2020). 10.1039/C9SM02180A Cited by (12) \| Cite \| Source
Quinoxaline and pyridopyrazine derivatives as PI3Kβ inhibitors (patent) Angibaud, Patrick Rene \| Querolle, Olivier Alexis Georges \| Berthelot, Didier Jean-Claude \| Meyer, Christophe \| Willot, Matthieu Philippe Victor \| Meerpoel, Lieven \| Jousseaume, Thierry Francois Alain Jean Patent Number: 10526316 (2020) Cite \| Source
Pyrazolyl quinoxaline kinase inhibitors (patent) Saxty, Gordon \| Murray, Christopher William \| Berdini, Valerio \| Besong, Gilbert Ebai \| Woodhead, Steven John \| Reader, Michael \| Mevellec, Laurence Anne \| Angibaud, Patrick René \| Freyne, Eddy Jean Edgard \| Perera, Timothy Pietro Suren \| ... \| Meerpoel, Lieven Patent Number: 10519137 (2019) Cited by (2) \| Cite \| Source
Substituted thiohydantoin derivatives as androgen receptor antagonists (patent) Bignan, Gilles \| Connolly, Peter J. \| Hickson, Ian \| Meerpoel, Lieven \| Pande, Vineet \| Zhang, Zhuming \| Branch, Jonathan \| Rocaboy, Christian \| Trabalón Escolar, Luis B. Patent Number: 10501469 (2019) Cite \| Source
Preparation of 4′‐Spirocyclobutyl Nucleoside Analogues as Novel and Versatile Adenosine Scaffolds (journal article) Verhoeven, Jonas \| De Vleeschouwer, Freija \| Kong, Hanchu \| Van Hecke, Kristof \| Pande, Vineet \| Sun, Weimei \| Vos, Ann \| Wu, Tongfei \| Meerpoel, Lieven \| Thuring, Jan Willem \| Verniest, Guido Chemistry – A European Journal, volume 25, issue 67, pages 15419-15423 (2019). 10.1002/chem.201904574 Cited by (11) \| Cite \| Source
Discovery and optimization of a series of small-molecule allosteric inhibitors of MALT1 protease (journal article) Lu, Tianbao \| Connolly, Peter J. \| Philippar, Ulrike \| Sun, Weimei \| Cummings, Maxwell D. \| Barbay, Kent \| Gys, Luc \| Van Nuffel, Luc \| Austin, Nigel \| Bekkers, Mariette \| ... \| Edwards, James Bioorganic & Medicinal Chemistry Letters, volume 29, issue 23, pages 126743- (2019). 10.1016/j.bmcl.2019.126743 Cited by (10) \| Cite \| Source
Deuterated triazolopyridazine as a kinase modulator (patent) Furer, Patrick Blasius \| Gilissen, Ronaldus Arnodus Hendrika Joseph \| Houpis, Ioannis Nicolaos \| Meerpoel, Lieven \| Perera, Timothy Pietro Suren \| Pye, Philip James Patent Number: 10464939 (2019) Cite \| Source
Substituted 4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrazine derivatives and 5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a][1,4]diazepine derivatives as Ros1 inhibitors (patent) Mevellec, Laurence Anne \| Pasquier, Elisabeth Therese Jeanne \| Descamps, Sophie \| Mercey, Guillaume Jean Maurice \| Wroblowski, Berthold \| Vialard, Jorge Eduardo \| Meerpoel, Lieven \| Jeanty, Matthieu Ludovic \| Jousseaume, Thierry Francois Alain Jean Patent Number: 10280170 (2019) Cite \| Source