Johannes S. Gach

ScholarGPS® ID: 46874203030020

Affiliation

University of California, Irvine, Irvine, United States

Affiliation History

Field

Life Sciences

Discipline

Molecular and Cell Biology

Top Specialties

Antibody | HIV | Vaccine | Virus | Immunodeficiency

Metrics Summary

Publication Count

Predicted Citations

2,032

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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SARS-CoV-2 infection of endothelial cells, dependent on flow-induced ACE2 expression, drives hypercytokinemia in a vascularized microphysiological system (journal article) Hatch, Christopher J. \| Piombo, Sebastian D. \| Fang, Jennifer S. \| Gach, Johannes S. \| Ewald, Makena L. \| Van Trigt, William K. \| Coon, Brian G. \| Tong, Jay M. \| Forthal, Donald N. \| Hughes, Christopher C. W. Frontiers in Cardiovascular Medicine, volume 11 (2024). 10.3389/fcvm.2024.1360364 Cited by (3) \| Cite \| Source
A genome‐edited N. benthamiana line for industrial‐scale production of recombinant glycoproteins with targeted N‐glycosylation (journal article) Kogelmann, Benjamin \| Melnik, Stanislav \| Bogner, Michaela \| Kallolimath, Somanath \| Stöger, Eva \| Sun, Lin \| Strasser, Richard \| D'Aoust, Marc‐André \| Lavoie, Pierre‐Olivier \| Saxena, Pooja \| ... \| Steinkellner, Herta Biotechnology Journal, volume 19, issue 1 (2024). 10.1002/biot.202300323 Cited by (4) \| Cite \| Source
In planta expression of active bacterial GDP‐6‐deoxy‐ d ‐lyxo‐4‐hexulose reductase for glycan modulation (journal article) Kogelmann, Benjamin \| Palt, Roman \| Maresch, Daniel \| Strasser, Richard \| Altmann, Friedrich \| Kallolimath, Somanath \| Sun, Lin \| D'Aoust, Marc‐André \| Lavoie, Pierre‐Olivier \| Saxena, Pooja \| ... \| Steinkellner, Herta Plant Biotechnology Journal, volume 21, issue 10, pages 1929-1931 (2023). 10.1111/pbi.14131 Cited by (1) \| Cite \| Source
An oligosaccharyltransferase from Leishmania donovani increases the N-glycan occupancy on plant-produced IgG1 (journal article) Beihammer, Gernot \| König-Beihammer, Julia \| Kogelmann, Benjamin \| Ruocco, Valentina \| Grünwald-Gruber, Clemens \| D’Aoust, Marc-André \| Lavoie, Pierre-Olivier \| Saxena, Pooja \| Gach, Johannes S. \| Steinkellner, Herta \| Strasser, Richard Frontiers in Plant Science, volume 14 (2023). 10.3389/fpls.2023.1233666 Cited by (3) \| Cite \| Source
Vaccination against SARS-CoV-2 using extracellular blebs derived from spike protein-expressing dendritic cells (journal article) Young Chung, Jee \| Thone, Melissa N. \| Davies, Jenny E. \| Gach, Johannes S. \| Huw Davies, D. \| Forthal, Donald N. \| Kwon, Young Jik Cellular Immunology, volume 386 (2023). 10.1016/j.cellimm.2023.104691 Cited by (4) \| Cite \| Source
Internalization of HIV-1 by Phagocytes Is Increased When Virions Are Opsonized with Multimeric Antibody in the Presence of Complement (journal article) Gach, Johannes S. \| Matsuno, Stephanie Y. \| Mercado, Mayalen \| Hangartner, Lars \| Forthal, Donald N. Journal of Virology, volume 96, issue 2 (2022). 10.1128/JVI.01689-21 Cited by (1) \| Cite \| Source
Diverse antiviral IgG effector activities are predicted by unique biophysical antibody features (journal article) Cheng, Hao D. \| Dowell, Karen G. \| Bailey-Kellogg, Chris \| Goods, Brittany A. \| Love, J. Christopher \| Ferrari, Guido \| Alter, Galit \| Gach, Johannes \| Forthal, Donald N. \| Lewis, George K. \| ... \| Ackerman, Margaret E. Retrovirology, volume 18, issue 1 (2021). 10.1186/s12977-021-00579-9 Cited by (6) \| Cite \| Source
Virus Control in Vaccinated Rhesus Macaques Is Associated with Neutralizing and Capturing Antibodies against the SHIV Challenge Virus but Not with V1V2 Vaccine–Induced Anti-V2 Antibodies Alone (journal article) Hessell, Ann J. \| Li, Liuzhe \| Malherbe, Delphine C. \| Barnette, Philip \| Pandey, Shilpi \| Sutton, William \| Spencer, David \| Wang, Xiao-Hong \| Gach, Johannes S. \| Hunegnaw, Ruth \| ... \| Gorny, Miroslaw K. The Journal of Immunology, volume 206, issue 6, pages 1266-1283 (2021). 10.4049/jimmunol.2001010 Cited by (6) \| Cite \| Source
Impact of Th 1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques (journal article) Verma, Anil \| Schmidt, Brian A. \| Elizaldi, Sonny R. \| Nguyen, Nancy K. \| Walter, Korey A. \| Beck, Zoltan \| Trinh, Hung V. \| Dinasarapu, Ashok R. \| Lakshmanappa, Yashavanth Shaan \| Rane, Niharika N. \| ... \| Iyer, Smita S. Journal of Virology, volume 94, issue 6 (2020). 10.1128/JVI.01737-19 Cited by (26) \| Cite \| Source
Antibody Responses Elicited by Immunization with BG505 Trimer Immune Complexes (journal article) Gach, Johannes S. \| Mara, Kane J. V. \| LaBranche, Celia C. \| van Gils, Marit J. \| McCoy, Laura E. \| Klasse, P. J. \| Montefiori, David C. \| Sanders, Rogier W. \| Moore, John P. \| Forthal, Donald N. Journal of Virology, volume 93, issue 20 (2019). 10.1128/JVI.01188-19 Cited by (10) \| Cite \| Source
Combination Adenovirus and Protein Vaccines Prevent Infection or Reduce Viral Burden after Heterologous Clade C Simian-Human Immunodeficiency Virus Mucosal Challenge (journal article) Malherbe, Delphine C. \| Mendy, Jason \| Vang, Lo \| Barnette, Philip T. \| Reed, Jason \| Lakhashe, Samir K. \| Owuor, Joshua \| Gach, Johannes S. \| Legasse, Alfred W. \| Axthelm, Michael K. \| ... \| Alexander, Jeff Journal of Virology, volume 92, issue 2 (2018). 10.1128/JVI.01092-17 Cited by (23) \| Cite \| Source
Human immunodeficiency virus type-1 (HIV-1) evades antibody-dependent phagocytosis (journal article) Gach, Johannes S. \| Bouzin, Margaux \| Wong, Marcus P. \| Chromikova, Veronika \| Gorlani, Andrea \| Yu, Kuan-Ting \| Sharma, Brijesh \| Gratton, Enrico \| Forthal, Donald N. PLOS Pathogens, volume 13, issue 12, pages e1006793- (2017). 10.1371/journal.ppat.1006793 Cited by (19) \| Cite \| Source \| Open Access
Relationship between Vaccine-Induced Antibody Capture of Infectious Virus and Infection Outcomes following Repeated Low-Dose Rectal Challenges with Simian Immunodeficiency Virus SIVmac251 (journal article) Gach, Johannes S. \| Venzon, David \| Vaccari, Monica \| Keele, Brandon F. \| Franchini, Genoveffa \| Forthal, Donald N. Journal of Virology, volume 90, issue 19, pages 8487-8495 (2016). 10.1128/JVI.00812-16 Cited by (7) \| Cite \| Source \| Open Access
Recent Insights into the HIV/AIDS Pandemic (journal article) Becerra, Juan C. \| Bildstein, Lukas S. \| Gach, Johannes S. Microbial Cell, volume 3, issue 9, pages 450-474 (2016). 10.15698/mic2016.09.529 Cited by (43) \| Cite \| Source \| Open Access
HIV-1-Specific Antibody Response and Function after DNA Prime and Recombinant Adenovirus 5 Boost HIV Vaccine in HIV-Infected Subjects (journal article) Gach, Johannes S. \| Gorlani, Andrea \| Dotsey, Emmanuel Y. \| Becerra, Juan C. \| Anderson, Chase T. M. \| Berzins, Baiba \| Felgner, Philip L. \| Forthal, Donald N. \| Deeks, Steven G. \| Wilkin, Timothy J. \| ... \| Achenbach, Chad J. PLOS ONE, volume 11, issue 8, pages e0160341- (2016). 10.1371/journal.pone.0160341 Cited by (14) \| Cite \| Source \| Open Access
Glycan modulation and sulfoengineering of anti–HIV-1 monoclonal antibody PG9 in plants (journal article) Loos, Andreas \| Gach, Johannes S. \| Hackl, Thomas \| Maresch, Daniel \| Henkel, Theresa \| Porodko, Andreas \| Bui-Minh, Duc \| Sommeregger, Wolfgang \| Wozniak-Knopp, Gordana \| Forthal, Donald N. \| ... \| Mach, Lukas Proceedings of the National Academy of Sciences, volume 112, issue 41, pages 12675-12680 (2015). 10.1073/pnas.1509090112 Cited by (42) \| Cite \| Source \| Open Access
HIV-specific CD4-induced Antibodies Mediate Broad and Potent Antibody-dependent Cellular Cytotoxicity Activity and are Commonly Detected in Plasma from HIV-infected Humans (journal article) Williams, Katherine L. \| Cortez, Valerie \| Dingens, Adam S. \| Gach, Johannes S. \| Rainwater, Stephanie \| Weis, Julie F. \| Chen, Xuemin \| Spearman, Paul \| Forthal, Donald N. \| Overbaugh, Julie EBioMedicine, volume 2, issue 10, pages 1464-1477 (2015). 10.1016/j.ebiom.2015.09.001 Cited by (45) \| Cite \| Source \| Open Access
A High Throughput Protein Microarray Approach to Classify HIV Monoclonal Antibodies and Variant Antigens (journal article) Dotsey, Emmanuel Y. \| Gorlani, Andrea \| Ingale, Sampat \| Achenbach, Chad J. \| Forthal, Donald N. \| Felgner, Philip L. \| Gach, Johannes S. PLOS ONE, volume 10, issue 5, pages e0125581- (2015). 10.1371/journal.pone.0125581 Cited by (12) \| Cite \| Source \| Open Access
Enhanced In Vitro Transcytosis of Simian Immunodeficiency Virus Mediated by Vaccine-Induced Antibody Predicts Transmitted/Founder Strain Number After Rectal Challenge (journal article) Gupta, Sandeep \| Pegu, Poonam \| Venzon, David J. \| Gach, Johannes S. \| Ma, Zhong-Min \| Landucci, Gary \| Miller, Christopher J. \| Franchini, Genoveffa \| Forthal, Donald N. Journal of Infectious Diseases, volume 211, issue 1, pages 45-52 (2015). 10.1093/infdis/jiu300 Cited by (10) \| Cite \| Source \| Open Access
Anti-p21 autoantibodies detected in colorectal cancer patients: A proof of concept study (journal article) Bishehsari, Faraz \| Gach, Johannes S \| Akagi, Naomi \| Webber, Molly K \| Bauer, Jessica \| Jung, Barbara H OncoImmunology, volume 3, issue 8, pages e952202- (2014). 10.4161/21624011.2014.952202 Cited by (4) \| Cite \| Source \| Open Access

Title	Investigators	Year	Cost	Agency
Impact of antibody mediated phagocytosis on HIV-1 clearance	Gach, Johannes S	2016	$77,250	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Impact of antibody mediated phagocytosis on HIV-1 clearance	Gach, Johannes S	2015	$77,250	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES