Julie Q. Hang

ScholarGPS® ID: 46624289252795

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

HIV | Nucleoside | Reverse Transcriptase

Metrics Summary

Publication Count

Predicted Citations

1,504

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Anti-Jagged1 antibodies and methods of use (patent) Chinn, Yvonne \| Hang, Julie Q. \| Siebel, Christian W. \| Wu, Yan \| Lafkas, Daniel Patent Number: 10858440 (2020) Cite \| Source
Anti-Jagged1 antibodies and methods of use (patent) Chinn, Yvonne \| Hang, Julie Q. \| Siebel, Christian W. \| Wu, Yan Patent Number: 10011661 (2018) Cite \| Source
Anti-Jagged1 antibodies and methods of use (patent) Chinn, Yvonne \| Hang, Julie Q. \| Siebel, Christian W. \| Wu, Yan Patent Number: 9518121 (2016) Cited by (1) \| Cite \| Source
The trimeric serine protease HtrA1 forms a cage-like inhibition complex with an anti-HtrA1 antibody (journal article) Ciferri, Claudio \| Lipari, Michael T. \| Liang, Wei-Ching \| Estevez, Alberto \| Hang, Julie \| Stawicki, Scott \| Wu, Yan \| Moran, Paul \| Elliott, Mike \| Eigenbrot, Charles \| ... \| Kirchhofer, Daniel Biochemical Journal, volume 472, issue 2, pages 169-181 (2015). 10.1042/BJ20150601 Cited by (19) \| Cite \| Source
Thymic stromal lymphopoietin receptor blockade reduces allergic inflammation in a cynomolgus monkey model of asthma (journal article) Cheng, Donavan T. \| Ma, Cynthia \| Niewoehner, Jens \| Dahl, Martin \| Tsai, Angela \| Zhang, Jun \| Gonsiorek, Waldemar \| Apparsundaram, Subbu \| Pashine, Achal \| Ravindran, Palanikumar \| ... \| Fuentes, Maria E. Journal of Allergy and Clinical Immunology, volume 132, issue 2, pages 455-462 (2013). 10.1016/j.jaci.2013.05.011 Cited by (44) \| Cite \| Source
The hepatitis C virus NS5A inhibitor (BMS-790052) alters the subcellular localization of the NS5A non-structural viral protein (journal article) Lee, Choongho \| Ma, Han \| Hang, Julie Qi \| Leveque, Vincent \| Sklan, Ella H. \| Elazar, Menashe \| Klumpp, Klaus \| Glenn, Jeffrey S. Virology, volume 414, issue 1, pages 10-18 (2011). 10.1016/j.virol.2011.03.026 Cited by (75) \| Cite \| Source \| Open Access
Exploration of piperidine-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-Phenyl derivatives with broad potency against resistant mutant viruses (journal article) Tang, Guozhi \| Kertesz, Denis J. \| Yang, Minmin \| Lin, Xianfeng \| Wang, Zhanguo \| Li, Wentao \| Qiu, Zongxing \| Chen, Junli \| Mei, Jianghua \| Chen, Li \| ... \| Klumpp, Klaus Bioorganic & Medicinal Chemistry Letters, volume 20, issue 20, pages 6020-6023 (2010). 10.1016/j.bmcl.2010.08.068 Cited by (30) \| Cite \| Source
Cyclic amide bioisosterism: Strategic application to the design and synthesis of HCV NS5B polymerase inhibitors (journal article) Yang, Hanbiao \| Hendricks, Robert T. \| Arora, Nidhi \| Nitzan, Dov \| Yee, Calvin \| Lucas, Matthew C. \| Yang, Yanli \| Fung, Amy \| Rajyaguru, Sonal \| Harris, Seth F. \| ... \| Tavares, Gisele A. Bioorganic & Medicinal Chemistry Letters, volume 20, issue 15, pages 4614-4619 (2010). 10.1016/j.bmcl.2010.06.008 Cited by (26) \| Cite \| Source
Discovery of piperidin-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-Benzyl derivatives with broad potency against resistant mutant viruses (journal article) Kertesz, Denis J. \| Brotherton-Pleiss, Christine \| Yang, Minmin \| Wang, Zhanguo \| Lin, Xianfeng \| Qiu, Zongxing \| Hirschfeld, Donald R. \| Gleason, Shelley \| Mirzadegan, Taraneh \| Dunten, Pete W. \| ... \| Klumpp, Klaus Bioorganic & Medicinal Chemistry Letters, volume 20, issue 14, pages 4215-4218 (2010). 10.1016/j.bmcl.2010.05.040 Cited by (64) \| Cite \| Source
Synthesis and biological activity of new pyridone diaryl ether non-nucleoside inhibitors of HIV-1 reverse transcriptase (journal article) Kennedy-Smith, Joshua J. \| Arora, Nidhi \| Billedeau, J. Roland \| Fretland, Jennifer \| Hang, Julie Q. \| Heilek, Gabrielle M. \| Harris, Seth F. \| Hirschfeld, Donald \| Javanbakht, Hassan \| Li, Yu \| ... \| Sweeney, Zachary K. MedChemComm, volume 1, issue 1, pages 79- (2010). 10.1039/c0md00009d Cited by (21) \| Cite \| Source
Slow Binding Inhibition and Mechanism of Resistance of Non-nucleoside Polymerase Inhibitors of Hepatitis C Virus (journal article) Hang, Julie Qi \| Yang, Yanli \| Harris, Seth F. \| Leveque, Vincent \| Whittington, Hannah J. \| Rajyaguru, Sonal \| Ao-Ieong, Gloria \| McCown, Matthew F. \| Wong, April \| Giannetti, Anthony M. \| ... \| Klumpp, Klaus Journal of Biological Chemistry, volume 284, issue 23, pages 15517-15529 (2009). 10.1074/jbc.M808889200 Cited by (86) \| Cite \| Source \| Open Access
Silibinin (Legalon-SIL) Inhibits HCV Replication In Vitro (journal article) Najera, Isabel \| Leveque, Vincent \| McCown, Matt \| Hang, Julie Q. \| Ma, Han \| Rajyaguru, Sonal \| Fung, Amy \| Yang, Yanli \| Liu, Yang \| Kular, Simran \| ... \| Klumpp, Klaus Antiviral Research, volume 82, issue 2, pages A30- (2009). 10.1016/j.antiviral.2009.02.053 Cite \| Source
2′-Deoxy-nucleoside Analogs can be Potent Dual Inhibitors of HCV and HIV Replication with Selectivity against Human Polymerases (journal article) Klumpp, Klaus \| Su, Guoping \| Leveque, Vincent \| Deval, Jerome \| Heilek, Gabrielle \| Rajyaguru, Sonal \| Li, Yu \| Hang, Julie Q. \| Ma, Han \| Inocencio, Nicole \| ... \| Najera, Isabel Antiviral Research, volume 82, issue 2, pages A19- (2009). 10.1016/j.antiviral.2009.02.021 Cite \| Source
Diphenyl Ether Non‐Nucleoside Reverse Transcriptase Inhibitors with Excellent Potency Against Resistant Mutant Viruses and Promising Pharmacokinetic Properties (journal article) Sweeney, Zachary K. \| Kennedy‐Smith, Joshua J. \| Wu, Jeffrey \| Arora, Nidhi \| Billedeau, J. Roland \| Davidson, James P. \| Fretland, Jennifer \| Hang, Julie Q. \| Heilek, Gabrielle M. \| Harris, Seth F. \| ... \| Klumpp, Klaus ChemMedChem, volume 4, issue 1, pages 88-99 (2009). 10.1002/cmdc.200800262 Cited by (26) \| Cite \| Source
Cover Picture: Diphenyl Ether Non‐Nucleoside Reverse Transcriptase Inhibitors with Excellent Potency Against Resistant Mutant Viruses and Promising Pharmacokinetic Properties (ChemMedChem 1/2009) (journal article) Sweeney, Zachary K. \| Kennedy‐Smith, Joshua J. \| Wu, Jeffrey \| Arora, Nidhi \| Billedeau, J. Roland \| Davidson, James P. \| Fretland, Jennifer \| Hang, Julie Q. \| Heilek, Gabrielle M. \| Harris, Seth F. \| ... \| Klumpp, Klaus ChemMedChem, volume 4, issue 1, pages 1-1 (2009). 10.1002/cmdc.200990000 Cited by (1) \| Cite \| Source
Design of Annulated Pyrazoles as Inhibitors of HIV-1 Reverse Transcriptase (journal article) Sweeney, Zachary K. \| Harris, Seth F. \| Arora, Nidhi \| Javanbakht, Hassan \| Li, Yu \| Fretland, Jennifer \| Davidson, James P. \| Billedeau, J. Roland \| Gleason, Shelley K. \| Hirschfeld, Donald \| ... \| Klumpp, Klaus Journal of Medicinal Chemistry, volume 51, issue 23, pages 7449-7458 (2008). 10.1021/jm800527x Cited by (68) \| Cite \| Source
Discovery of triazolinone non-nucleoside inhibitors of HIV reverse transcriptase (journal article) Sweeney, Zachary K. \| Acharya, Sahaja \| Briggs, Andrew \| Dunn, James P. \| Elworthy, Todd R. \| Fretland, Jennifer \| Giannetti, Anthony M. \| Heilek, Gabrielle \| Li, Yu \| Kaiser, Ann C. \| ... \| Klumpp, Klaus Bioorganic & Medicinal Chemistry Letters, volume 18, issue 15, pages 4348-4351 (2008). 10.1016/j.bmcl.2008.06.080 Cited by (29) \| Cite \| Source
Design, synthesis, and antiviral properties of 4′-substituted ribonucleosides as inhibitors of hepatitis C virus replication: The discovery of R1479 (journal article) Smith, David B. \| Martin, Joseph A. \| Klumpp, Klaus \| Baker, Stewart J. \| Blomgren, Peter A. \| Devos, Rene \| Granycome, Caroline \| Hang, Julie \| Hobbs, Christopher J. \| Jiang, Wen-Rong \| ... \| Cammack, Nick Bioorganic & Medicinal Chemistry Letters, volume 17, issue 9, pages 2570-2576 (2007). 10.1016/j.bmcl.2007.02.004 Cited by (102) \| Cite \| Source
Substrate-dependent inhibition or stimulation of HIV RNase H activity by non-nucleoside reverse transcriptase inhibitors (NNRTIs) (journal article) Hang, Julie Q. \| Li, Yu \| Yang, Yanli \| Cammack, Nick \| Mirzadegan, Tara \| Klumpp, Klaus Biochemical and Biophysical Research Communications, volume 352, issue 2, pages 341-350 (2007). 10.1016/j.bbrc.2006.11.018 Cited by (44) \| Cite \| Source
The Novel Nucleoside Analog R1479 (4′-Azidocytidine) Is a Potent Inhibitor of NS5B-dependent RNA Synthesis and Hepatitis C Virus Replication in Cell Culture (journal article) Klumpp, Klaus \| Lévêque, Vincent \| Le Pogam, Sophie \| Ma, Han \| Jiang, Wen-Rong \| Kang, Hyunsoon \| Granycome, Caroline \| Singer, Margaret \| Laxton, Carl \| Hang, Julie Qi \| ... \| Nájera, Isabel Journal of Biological Chemistry, volume 281, issue 7, pages 3793-3799 (2006). 10.1074/jbc.M510195200 Cited by (223) \| Cite \| Source \| Open Access