Robert M. Pitti

ScholarGPS® ID: 46582055022008

Affiliation
Genentech, Inc., South San Francisco, United States
Affiliation History

Field
Medicine
Discipline
Oncology
Top Specialties
Neoplasm | Apoptosis | Tumor Necrosis Factor Alpha | Cancer
Metrics Summary
Publication Count
32
Predicted Citations
11,028
Predicted h-index
25
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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Proteomic Analyses Identify a Novel Role for EZH2 in the Initiation of Cancer Cell Drug Tolerance (journal article)
Pham, Victoria | Pitti, Robert | Tindell, Charles A. | Cheung, Tommy K. | Masselot, Alexandre | Stephan, Jean-Phillipe | Guler, Gulfem D. | Wilson, Catherine | Lill, Jennie | Arnott, David | Classon, Marie
Journal of Proteome Research, volume 19, issue 4, pages 1533-1547 (2020).
10.1021/acs.jproteome.9b00773
Cited by (15) | Cite | Source
Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations from Lethal Drug Exposure (journal article)
Guler, Gulfem Dilek | Tindell, Charles Albert | Pitti, Robert | Wilson, Catherine | Nichols, Katrina | KaiWai Cheung, Tommy | Kim, Hyo-Jin | Wongchenko, Matthew | Yan, Yibing | Haley, Benjamin | ... | Classon, Marie
Cancer Cell, volume 32, issue 2, pages 221-237.e13 (2017).
10.1016/j.ccell.2017.07.002
Cited by (155) | Cite | Source
TRAF2 Sets a Threshold for Extrinsic Apoptosis by Tagging Caspase-8 with a Ubiquitin Shutoff Timer (journal article)
Gonzalvez, Francois | Lawrence, David | Yang, Becky | Yee, Sharon | Pitti, Robert | Marsters, Scot | Pham, Victoria C. | Stephan, Jean-Philippe | Lill, Jennie | Ashkenazi, Avi
Molecular Cell, volume 48, issue 6, pages 888-899 (2012).
10.1016/j.molcel.2012.09.031
Cited by (130) | Cite | Source | Open Access
Proapoptotic Activation of Death Receptor 5 on Tumor Endothelial Cells Disrupts the Vasculature and Reduces Tumor Growth (journal article)
Wilson, Nicholas S. | Yang, Annie | Yang, Becky | Couto, Suzana | Stern, Howard | Gogineni, Alvin | Pitti, Robert | Marsters, Scot | Weimer, Robby M. | Singh, Mallika | Ashkenazi, Avi
Cancer Cell, volume 22, issue 1, pages 80-90 (2012).
10.1016/j.ccr.2012.05.014
Cited by (49) | Cite | Source | Open Access
Complementary Proteomic Tools for the Dissection of Apoptotic Proteolysis Events (journal article)
Pham, Victoria C. | Pitti, Robert | Anania, Veronica G. | Bakalarski, Corey E. | Bustos, Daisy | Jhunjhunwala, Suchit | Phung, Qui T. | Yu, Kebing | Forrest, William F. | Kirkpatrick, Donald S. | ... | Lill, Jennie R.
Journal of Proteome Research, volume 11, issue 5, pages 2947-2954 (2012).
10.1021/pr300035k
Cited by (21) | Cite | Source
An Fcγ Receptor-Dependent Mechanism Drives Antibody-Mediated Target-Receptor Signaling in Cancer Cells (journal article)
Wilson, Nicholas S. | Yang, Becky | Yang, Annie | Loeser, Stefanie | Marsters, Scot | Lawrence, David | Li, Yun | Pitti, Robert | Totpal, Klara | Yee, Sharon | ... | Ashkenazi, Avi
Cancer Cell, volume 19, issue 1, pages 101-113 (2011).
10.1016/j.ccr.2010.11.012
Cited by (273) | Cite | Source | Open Access
Cullin3-Based Polyubiquitination and p62-Dependent Aggregation of Caspase-8 Mediate Extrinsic Apoptosis Signaling (journal article)
Jin, Zhaoyu | Li, Yun | Pitti, Robert | Lawrence, David | Pham, Victoria C. | Lill, Jennie R. | Ashkenazi, Avi
Cell, volume 137, issue 4, pages 721-735 (2009).
10.1016/j.cell.2009.03.015
Cited by (524) | Cite | Source | Open Access
Identification of potentially predictive biomarkers for tumor sensitivity to proapoptotic receptor agonists (journal article)
Ashkenazi, A. | Wagner, K. | Punnnoose, E. | Lawrence, D. | Pitti, R. | Amler, L.
Journal of Clinical Oncology, volume 26, issue 15_suppl, pages 14505-14505 (2008).
10.1200/jco.2008.26.15_suppl.14505
Cite | Source
Structural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5 (journal article)
Adams, C | Totpal, K | Lawrence, D | Marsters, S | Pitti, R | Yee, S | Ross, S | Deforge, L | Koeppen, H | Sagolla, M | ... | Ashkenazi, A
Cell Death & Differentiation, volume 15, issue 4, pages 751-761 (2008).
10.1038/sj.cdd.4402306
Cited by (127) | Cite | Source | Open Access
Apo-3 ligand polypeptide (patent)
Ashkenazi, Avi | Marsters, Scot A. | Pitti, Robert M.
Patent Number: 20080213837 (2007)
Cited by (1) | Cite | Source
Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL (journal article)
Wagner, Klaus W | Punnoose, Elizabeth A | Januario, Thomas | Lawrence, David A | Pitti, Robert M | Lancaster, Kate | Lee, Dori | von Goetz, Melissa | Yee, Sharon Fong | Totpal, Klara | ... | Ashkenazi, Avi
Nature Medicine, volume 13, issue 9, pages 1070-1077 (2007).
10.1038/nm1627
Cited by (512) | Cite | Source
Antibodies to DcR3 Polypeptide, a TNFR Homolog (patent)
Ashkenazi, Avi J. | Botstein, David | Dodge, Kelly H. | Goddard, Audrey | Gurney, Austin L. | Kim, Kyung Jin | Lawrence, David A. | Pitti, Robert | Roy, Margaret A. | Tumas, Daniel B. | Wood, William I.
Patent Number: 6764679 (2004)
Cited by (4) | Cite | Source
Substitutional variants of APO-2 ligand (patent)
Ashkenazi, Avi J. | Kelley, Robert F. | Pitti, Robert M. | Schwall, Ralph A.
Patent Number: 6740739 (2004)
Cited by (7) | Cite | Source
Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI (journal article)
Marsters, Scot A | Yan, Minhong | Pitti, Robert M | Haas, Philip E | Dixit, Vishva M | Ashkenazi, Avi
Current Biology, volume 10, issue 13, pages 785-788 (2000).
10.1016/S0960-9822(00)00566-2
Cited by (324) | Cite | Source | Open Access
Compositions and methods for the treatment of tumor (patent)
Ashkenazi, Avi | Goddard, Audrey | Godowski, Paul J. | Gurney, Austin L. | Hillan, Kenneth J. | Marsters, Scot A. | Pan, James | Pitti, Robert M. | Roy, Margaret Ann | Smith, Victoria | ... | Wood, William I.
Patent Number: 20030170228 (2000)
Cited by (36) | Cite | Source
Novel tumor necrosis factor receptor homolog and nucleic acids encoding the same (patent)
Ashkenazi, Avi | Goddard, Audrey | Gurney, Austin L. | Marsters, Scot A. | Pitti, Robert M. | Wood, William I.
Patent Number: 20020150993 (1999)
Cited by (8) | Cite | Source
Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR (journal article)
Gurney, A.L. | Marsters, S.A. | Huang, A. | Pitti, R.M. | Mark, M. | Baldwin, D.T. | Gray, A.M. | Dowd, P. | Brush, J. | Heldens, S. | ... | Ashkenazi, A.
Current Biology, volume 9, issue 4, pages 215-218 (1999).
10.1016/S0960-9822(99)80093-1
Cited by (185) | Cite | Source | Open Access
Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer (journal article)
Pitti, Robert M. | Marsters, Scot A. | Lawrence, David A. | Roy, Margaret | Kischkel, Frank C. | Dowd, Patrick | Huang, Arthur | Donahue, Christopher J. | Sherwood, Steven W. | Baldwin, Daryl T. | ... | Ashkenazi, Avi
Nature, volume 396, issue 6712, pages 699-703 (1998).
10.1038/25387
Cited by (670) | Cite | Source
DNA19355 polypeptide, a tumor necrosis factor homolog (patent)
Ashkenazi, Avi | Baker, Kevin P. | Godowski, Paul J. | Gurney, Austin L. | Mark, Melanie R. | Marsters, Scot A. | Pitti, Robert M.
Patent Number: 20060216270 (1998)
Cite | Source
DcR3 POLYPEPTIDE, A TNFR HOMOLOG (patent)
Ashkenazi, Avi | Botstein, David Belmont | Dodge, Kelly H. | Goddard, Audrey San Francisco | Gurney, Austin L. | Kim, Kyung Jin | Lawrence, David A. | Pitti, Robert El Cerrito | Roy, Margaret Ann | Tumas, Daniel | Wood, William I.
Patent Number: 20040014176 (1998)
Cite | Source