Fergus E. Poynton

ScholarGPS® ID: 46269297087565

Affiliation

Trinity College Dublin, Dublin, Ireland

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

DNA | Photography | Base Pair

Metrics Summary

Publication Count

Predicted Citations

1,098

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Tracking the cellular uptake and phototoxicity of Ru( ii )-polypyridyl-1,8-naphthalimide Tröger's base conjugates (journal article) Bright, Sandra A. \| Erby, MariaLuisa \| Poynton, Fergus E. \| Monteyne, Daniel \| Pérez-Morga, David \| Gunnlaugsson, Thorfinnur \| Williams, D. Clive \| Elmes, Robert B. P. RSC Chemical Biology, volume 5, issue 4, pages 344-359 (2024). 10.1039/D3CB00206C Cite \| Source
Time-resolved infra-red studies of photo-excited porphyrins in the presence of nucleic acids and in HeLa tumour cells: insights into binding site and electron transfer dynamics (journal article) Keane, Páraic M. \| Zehe, Clara \| Poynton, Fergus E. \| Bright, Sandra A. \| Estayalo-Adrián, Sandra \| Devereux, Stephen J. \| Donaldson, Paul M. \| Sazanovich, Igor V. \| Towrie, Michael \| Botchway, Stanley W. \| ... \| Quinn, Susan J. Physical Chemistry Chemical Physics, volume 24, issue 44, pages 27524-27531 (2022). 10.1039/D2CP04604K Cited by (6) \| Cite \| Source
Caught in the Loop: Binding of the [Ru(phen)2 (dppz)]2+ Light‐Switch Compound to Quadruplex DNA in Solution Informed by Time‐Resolved Infrared Spectroscopy (journal article) Devereux, Stephen J. \| Poynton, Fergus E. \| Baptista, Frederico R. \| Gunnlaugsson, Thorfinnur \| Cardin, Christine J. \| Sazanovich, Igor V. \| Towrie, Michael \| Kelly, John M. \| Quinn, Susan J. Chemistry – A European Journal, volume 26, issue 71, pages 17103-17109 (2020). 10.1002/chem.202002165 Cited by (11) \| Cite \| Source
446 Immunopeptidome changes mediated by a novel ERAP1 inhibitor leads to tumor growth inhibition (conference) Joyce, Peter \| Young, Lesley \| Quibell, Martin \| Shiers, Jason \| Tong, Carmen \| Clark, Kristopher \| James, Edd \| Reeves, Emma \| Remtulla, Alihussein \| Leonard, Henry \| ... \| Leishman, Andrew 35th Anniversary Annual Meeting (SITC 2020) (2020) 10.1136/jitc-2020-SITC2020.0446 Cited by (1) \| Cite \| Source
Understanding the factors controlling the photo-oxidation of natural DNA by enantiomerically pure intercalating ruthenium polypyridyl complexes through TA/TRIR studies with polydeoxynucleotides and mixed sequence oligodeoxynucleotides (journal article) Keane, Páraic M. \| O'Sullivan, Kyra \| Poynton, Fergus E. \| Poulsen, Bjørn C. \| Sazanovich, Igor V. \| Towrie, Michael \| Cardin, Christine J. \| Sun, Xue-Zhong \| George, Michael W. \| Gunnlaugsson, Thorfinnur \| ... \| Kelly, John M. Chemical Science, volume 11, issue 32, pages 8600-8609 (2020). 10.1039/D0SC02413A Cited by (17) \| Cite \| Source
Nanotechnology based therapeutics for lung disease (journal article) Doroudian, Mohammad \| MacLoughlin, Ronan \| Poynton, Fergus \| Prina-Mello, Adriele \| Donnelly, Seamas C Thorax, volume 74, issue 10, pages 965-976 (2019). 10.1136/thoraxjnl-2019-213037 Cited by (71) \| Cite \| Source
Inosine Can Increase DNA′s Susceptibility to Photo‐oxidation by a RuII Complex due to Structural Change in the Minor Groove (journal article) Keane, Páraic M. \| Hall, James P. \| Poynton, Fergus E. \| Poulsen, Bjørn C. \| Gurung, Sarah P. \| Clark, Ian P. \| Sazanovich, Igor V. \| Towrie, Michael \| Gunnlaugsson, Thorfinnur \| Quinn, Susan J. \| ... \| Kelly, John M. Chemistry – A European Journal, volume 23, issue 43, pages 10344-10351 (2017). 10.1002/chem.201701447 Cited by (16) \| Cite \| Source
The development of ruthenium( ii ) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications (journal article) Poynton, Fergus E. \| Bright, Sandra A. \| Blasco, Salvador \| Williams, D. Clive \| Kelly, John M. \| Gunnlaugsson, Thorfinnur Chemical Society Reviews, volume 46, issue 24, pages 7706-7756 (2017). 10.1039/C7CS00680B Cited by (337) \| Cite \| Source
DNA structure and dynamics – a combinational approach (journal article) Hall, James P. \| Gurung, Sarah P. \| Keane, Paraic M. \| Poynton, Fergus E. \| Cardin, David J. \| Sorensen, Thomas \| Winter, Graeme \| Gunnlaugsson, Thorfinnur \| Sazanovich, Igor V. \| Towrie, Mike \| ... \| Cardin, Christine J. Acta Crystallographica Section A Foundations and Advances, volume 72, issue a1, pages s49-s50 (2016). 10.1107/S205327331609923X Cite \| Source \| Open Access
Direct observation by time-resolved infrared spectroscopy of the bright and the dark excited states of the [Ru(phen)2 (dppz)]2+ light-switch compound in solution and when bound to DNA (journal article) Poynton, Fergus E. \| Hall, James P. \| Keane, Páraic M. \| Schwarz, Christine \| Sazanovich, Igor V. \| Towrie, Michael \| Gunnlaugsson, Thorfinnur \| Cardin, Christine J. \| Cardin, David J. \| Quinn, Susan J. \| ... \| Kelly, John M. Chemical Science, volume 7, issue 5, pages 3075-3084 (2016). 10.1039/C5SC04514B Cited by (51) \| Cite \| Source \| Open Access
Monitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopy (journal article) Hall, James P. \| Poynton, Fergus E. \| Keane, Páraic M. \| Gurung, Sarah P. \| Brazier, John A. \| Cardin, David J. \| Winter, Graeme \| Gunnlaugsson, Thorfinnur \| Sazanovich, Igor V. \| Towrie, Michael \| ... \| Quinn, Susan J. Nature Chemistry, volume 7, issue 12, pages 961-967 (2015). 10.1038/nchem.2369 Cited by (63) \| Cite \| Source
Combining X-ray crystallography and ultrafast infrared spectroscopy – monitoring photo-induced guanine oxidation by [Ru(TAP)2 (dppz)]2+ (journal article) Hall, James P. \| Poynton, Fergus E. \| Keane, Páraic M. \| Gurung, Sarah P. \| Brazier, John A. \| Cardin, David J. \| Winter, Graeme \| Gunnlaugsson, Thorfinnur \| Sazanovich, Igor V. \| Towrie, Michael \| ... \| Quinn, Susan J. Acta Crystallographica Section A Foundations and Advances, volume 71, issue a1, pages s492-s493 (2015). 10.1107/S205327331509275X Cite \| Source \| Open Access
Frontispiece: Reversal of a Single Base‐Pair Step Controls Guanine Photo‐Oxidation by an Intercalating Ruthenium(II) Dipyridophenazine Complex (journal article) Keane, Páraic M. \| Poynton, Fergus E. \| Hall, James P. \| Sazanovich, Igor V. \| Towrie, Michael \| Gunnlaugsson, Thorfinnur \| Quinn, Susan J. \| Cardin, Christine J. \| Kelly, John M. Angewandte Chemie International Edition, volume 54, issue 29 (2015). 10.1002/anie.201582961 Cite \| Source \| Open Access
Frontispiz: Reversal of a Single Base‐Pair Step Controls Guanine Photo‐Oxidation by an Intercalating Ruthenium(II) Dipyridophenazine Complex (journal article) Keane, Páraic M. \| Poynton, Fergus E. \| Hall, James P. \| Sazanovich, Igor V. \| Towrie, Michael \| Gunnlaugsson, Thorfinnur \| Quinn, Susan J. \| Cardin, Christine J. \| Kelly, John M. Angewandte Chemie, volume 127, issue 29 (2015). 10.1002/ange.201582961 Cite \| Source \| Open Access
Reversal of a Single Base‐Pair Step Controls Guanine Photo‐Oxidation by an Intercalating Ruthenium(II) Dipyridophenazine Complex (journal article) Keane, Páraic M. \| Poynton, Fergus E. \| Hall, James P. \| Sazanovich, Igor V. \| Towrie, Michael \| Gunnlaugsson, Thorfinnur \| Quinn, Susan J. \| Cardin, Christine J. \| Kelly, John M. Angewandte Chemie International Edition, volume 54, issue 29, pages 8364-8368 (2015). 10.1002/anie.201502608 Cited by (33) \| Cite \| Source \| Open Access
Reversal of a Single Base‐Pair Step Controls Guanine Photo‐Oxidation by an Intercalating Ruthenium(II) Dipyridophenazine Complex (journal article) Keane, Páraic M. \| Poynton, Fergus E. \| Hall, James P. \| Sazanovich, Igor V. \| Towrie, Michael \| Gunnlaugsson, Thorfinnur \| Quinn, Susan J. \| Cardin, Christine J. \| Kelly, John M. Angewandte Chemie, volume 127, issue 29, pages 8484-8488 (2015). 10.1002/ange.201502608 Cited by (12) \| Cite \| Source \| Open Access
Detailed Biological Profiling of a Photoactivated and Apoptosis Inducing pdppz Ruthenium(II) Polypyridyl Complex in Cancer Cells (journal article) Cloonan, Suzanne M. \| Elmes, Robert B. P. \| Erby, MariaLuisa \| Bright, Sandra A. \| Poynton, Fergus E. \| Nolan, Derek E. \| Quinn, Susan J. \| Gunnlaugsson, Thorfinnur \| Williams, D. Clive Journal of Medicinal Chemistry, volume 58, issue 11, pages 4494-4505 (2015). 10.1021/acs.jmedchem.5b00451 Cited by (76) \| Cite \| Source
Enantiomeric Conformation Controls Rate and Yield of Photoinduced Electron Transfer in DNA Sensitized by Ru(II) Dipyridophenazine Complexes (journal article) Keane, Páraic M. \| Poynton, Fergus E. \| Hall, James P. \| Clark, Ian P. \| Sazanovich, Igor V. \| Towrie, Michael \| Gunnlaugsson, Thorfinnur \| Quinn, Susan J. \| Cardin, Christine J. \| Kelly, John M. The Journal of Physical Chemistry Letters, volume 6, issue 4, pages 734-738 (2015). 10.1021/jz502743q Cited by (29) \| Cite \| Source
Monitoring guanine photo-oxidation by enantiomerically resolved Ru( ii ) dipyridophenazine complexes using inosine-substituted oligonucleotides (journal article) Keane, Páraic M. \| Poynton, Fergus E. \| Hall, James P. \| Clark, Ian P. \| Sazanovich, Igor V. \| Towrie, Michael \| Gunnlaugsson, Thorfinnur \| Quinn, Susan J. \| Cardin, Christine J. \| Kelly, John M. Faraday Discussions, volume 185 (2015). 10.1039/C5FD00085H Cited by (12) \| Cite \| Source
Unexpected DNA binding properties with correlated downstream biological applications in mono vs. bis-1,8-naphthalimide Ru( ii )-polypyridyl conjugates (journal article) Ryan, Gary J. \| Poynton, Fergus E. \| Elmes, Robert B. P. \| Erby, Marialuisa \| Williams, D. Clive \| Quinn, Susan J. \| Gunnlaugsson, Thorfinnur Dalton Transactions, volume 44, issue 37, pages 16332-16344 (2015). 10.1039/C5DT00360A Cited by (36) \| Cite \| Source \| Open Access