Karin J. Purdie

ScholarGPS® ID: 45786591833457

Affiliation

Barts and The London School of Medicine and Dentistry, London, United Kingdom

Affiliation History

Field

Life Sciences

Discipline

Molecular and Cell Biology

Top Specialties

Squamous Cell Carcinoma | Human Papillomavirus Infection | Cancer | Genomics | Mutation

Metrics Summary

Publication Count

Predicted Citations

2,836

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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The Genomic Landscape of Actinic Keratosis (journal article) Thomson, Jason \| Bewicke-Copley, Findlay \| Anene, Chinedu Anthony \| Gulati, Abha \| Nagano, Ai \| Purdie, Karin \| Inman, Gareth J. \| Proby, Charlotte M. \| Leigh, Irene M. \| Harwood, Catherine A. \| Wang, Jun Journal of Investigative Dermatology, volume 141, issue 7, pages 1664-1674.e7 (2021). 10.1016/j.jid.2020.12.024 Cited by (36) \| Cite \| Source
Epigenetic Regulation of iASPP-p63 Feedback Loop in Cutaneous Squamous Cell Carcinoma (journal article) Robinson, Deborah J. \| Patel, Ankit \| Purdie, Karin J. \| Wang, Jun \| Rizvi, Hasan \| Hufbauer, Martin \| Ostano, Paola \| Akgül, Baki \| Chiorino, Giovanna \| Harwood, Catherine A. \| Bergamaschi, Daniele Journal of Investigative Dermatology, volume 139, issue 8, pages 1658-1671.e8 (2019). 10.1016/j.jid.2019.01.020 Cited by (14) \| Cite \| Source
A Unique Panel of Patient-Derived Cutaneous Squamous Cell Carcinoma Cell Lines Provides a Preclinical Pathway for Therapeutic Testing (journal article) Hassan, Sakinah \| Purdie, Karin J. \| Wang, Jun \| Harwood, Catherine A. \| Proby, Charlotte M. \| Pourreyron, Celine \| Mladkova, Nikol \| Nagano, Ai \| Dhayade, Sandeep \| Athineos, Dimitris \| ... \| Leigh, Irene M. International Journal of Molecular Sciences, volume 20, issue 14, pages 3428- (2019). 10.3390/ijms20143428 Cited by (16) \| Cite \| Source
The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature (journal article) Inman, Gareth J. \| Wang, Jun \| Nagano, Ai \| Alexandrov, Ludmil B. \| Purdie, Karin J. \| Taylor, Richard G. \| Sherwood, Victoria \| Thomson, Jason \| Hogan, Sarah \| Spender, Lindsay C. \| ... \| Leigh, Irene M. Nature Communications, volume 9, issue 1 (2018). 10.1038/s41467-018-06027-1 Cited by (194) \| Cite \| Source \| Open Access
The Role of Human Papillomaviruses and Polyomaviruses in BRAF-Inhibitor Induced Cutaneous Squamous Cell Carcinoma and Benign Squamoproliferative Lesions (journal article) Purdie, Karin J. \| Proby, Charlotte M. \| Rizvi, Hasan \| Griffin, Heather \| Doorbar, John \| Sommerlad, Mary \| Feltkamp, Mariet C. \| Meijden, Els Van der \| Inman, Gareth J. \| South, Andrew P. \| ... \| Harwood, Catherine A. Frontiers in Microbiology, volume 9 (2018). 10.3389/fmicb.2018.01806 Cited by (21) \| Cite \| Source \| Open Access
Reduced SMAD2/3 activation independently predicts increased depth of human cutaneous squamous cell carcinoma (journal article) Rose, Aidan M. \| Spender, Lindsay C. \| Stephen, Christopher \| Mitchell, Alastair \| Rickaby, William \| Bray, Susan \| Evans, Alan T. \| Dayal, Jasbani \| Purdie, Karin J. \| Harwood, Catherine A. \| ... \| Inman, Gareth J. Oncotarget, volume 9, issue 18, pages 14552-14566 (2018). 10.18632/oncotarget.24545 Cited by (7) \| Cite \| Source \| Open Access
Genomic analysis of atypical fibroxanthoma (journal article) Lai, Kevin \| Harwood, Catherine A. \| Purdie, Karin J. \| Proby, Charlotte M. \| Leigh, Irene M. \| Ravi, Namita \| Mully, Thaddeus W. \| Brooks, Lionel \| Sandoval, Priscilla M. \| Rosenblum, Michael D. \| Arron, Sarah T. PLOS ONE, volume 12, issue 11, pages e0188272- (2017). 10.1371/journal.pone.0188272 Cited by (28) \| Cite \| Source \| Open Access
131 Stressed out keratinocytes, new insights into psoriasis lesion formation (journal article) Hannen, R.F. \| Asher, S. \| Mannella, V. \| Purdie, K. \| Leigh, I. \| Philpott, M. Journal of Investigative Dermatology, volume 137, issue 10, pages S215- (2017). 10.1016/j.jid.2017.07.441 Cite \| Source
Whole-Exome Sequencing Validates a Preclinical Mouse Model for the Prevention and Treatment of Cutaneous Squamous Cell Carcinoma (journal article) Knatko, Elena V. \| Praslicka, Brandon \| Higgins, Maureen \| Evans, Alan \| Purdie, Karin J. \| Harwood, Catherine A. \| Proby, Charlotte M. \| Ooi, Aikseng \| Dinkova-Kostova, Albena T. Cancer Prevention Research, volume 10, issue 1, pages 67-75 (2017). 10.1158/1940-6207.CAPR-16-0218 Cited by (18) \| Cite \| Source \| Open Access
Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma (journal article) Cammareri, Patrizia \| Rose, Aidan M. \| Vincent, David F. \| Wang, Jun \| Nagano, Ai \| Libertini, Silvana \| Ridgway, Rachel A. \| Athineos, Dimitris \| Coates, Philip J. \| McHugh, Angela \| ... \| Inman, Gareth J. Nature Communications, volume 7, issue 1 (2016). 10.1038/ncomms12493 Cited by (79) \| Cite \| Source \| Open Access
CREBBP mutation in human cutaneous squamous cell carcinoma (journal article) Watt, Stephen A. \| Purdie, Karin J. \| den Breems, Nicoline Y. \| Dimon, Michelle \| Tucker, Stefan \| Arron, Sarah T. \| McHugh, Angela \| Xue, Dylan J. \| Dayal, Jasbani H.S. \| Harwood, Catherine A. \| ... \| South, Andrew P. Experimental Dermatology, volume 25, issue 8, pages 650-651 (2016). 10.1111/exd.13044 Cited by (6) \| Cite \| Source \| Open Access
HLA Immunogenotype Determines Persistent Human Papillomavirus Virus Infection in HIV-Infected Patients Receiving Antiretroviral Treatment (journal article) Meys, Rhonda \| Purdie, Karin J. \| de Koning, Maurits N. C. \| Quint, Koen D. \| Little, Ann-Margaret \| Baker, Finnuala \| Francis, Nick \| Asboe, David \| Hawkins, David \| Marsh, Steven G. E. \| ... \| Bunker, Christopher B. Journal of Infectious Diseases, volume 213, issue 11, pages 1717-1724 (2016). 10.1093/infdis/jiw038 Cited by (6) \| Cite \| Source \| Open Access
100 The genomic landscape of atypical fibroxanthoma (journal article) Lai, K. \| Harwood, C. \| Purdie, K. \| Proby, C. \| Brooks, L. \| Arron, S. Journal of Investigative Dermatology, volume 136, issue 5, pages S18- (2016). 10.1016/j.jid.2016.02.126 Cite \| Source \| Open Access
Novel CARD11 Mutations in Human Cutaneous Squamous Cell Carcinoma Lead to Aberrant NF-κB Regulation (journal article) Watt, Stephen A. \| Purdie, Karin J. \| den Breems, Nicoline Y. \| Dimon, Michelle \| Arron, Sarah T. \| McHugh, Angela T. \| Xue, Dylan J. \| Dayal, Jasbani H.S. \| Proby, Charlotte M. \| Harwood, Catherine A. \| ... \| South, Andrew P. The American Journal of Pathology, volume 185, issue 9, pages 2354-2363 (2015). 10.1016/j.ajpath.2015.05.018 Cited by (20) \| Cite \| Source \| Open Access
NOTCH1 Mutations Occur Early during Cutaneous Squamous Cell Carcinogenesis (journal article) South, Andrew P. \| Purdie, Karin J. \| Watt, Stephen A. \| Haldenby, Sam \| den Breems, Nicoline Y. \| Dimon, Michelle \| Arron, Sarah T. \| Kluk, Michael J. \| Aster, Jon C. \| McHugh, Angela \| ... \| Leigh, Irene M. Journal of Investigative Dermatology, volume 134, issue 10, pages 2630-2638 (2014). 10.1038/jid.2014.154 Cited by (279) \| Cite \| Source \| Open Access
The telomere profile distinguishes two classes of genetically distinct cutaneous squamous cell carcinomas (journal article) Leufke, C \| Leykauf, J \| Krunic, D \| Jauch, A \| Holtgreve-Grez, H \| Böhm-Steuer, B \| Bröcker, E-B \| Mauch, C \| Utikal, J \| Hartschuh, W \| ... \| Boukamp, P Oncogene, volume 33, issue 27, pages 3506-3518 (2014). 10.1038/onc.2013.323 Cited by (15) \| Cite \| Source
Key differences identified between actinic keratosis and cutaneous squamous cell carcinoma by transcriptome profiling (journal article) Lambert, S R \| Mladkova, N \| Gulati, A \| Hamoudi, R \| Purdie, K \| Cerio, R \| Leigh, I \| Proby, C \| Harwood, C A British Journal of Cancer, volume 110, issue 2, pages 520-529 (2014). 10.1038/bjc.2013.760 Cited by (84) \| Cite \| Source \| Open Access
Exploiting FOXM1‐orchestrated molecular network for early squamous cell carcinoma diagnosis and prognosis (journal article) Teh, Muy‐Teck \| Hutchison, Iain L. \| Costea, Daniela Elena \| Neppelberg, Evelyn \| Liavaag, Per Gunnar \| Purdie, Karin \| Harwood, Catherine \| Wan, Hong \| Odell, Edward W. \| Hackshaw, Allan \| Waseem, Ahmad International Journal of Cancer, volume 132, issue 9, pages 2095-2106 (2013). 10.1002/ijc.27886 Cited by (30) \| Cite \| Source \| Open Access
Metastatic cutaneous squamous cell carcinoma shows frequent deletion in the protein tyrosine phosphatase receptor Type D gene (journal article) Lambert, Sally R. \| Harwood, Catherine A. \| Purdie, Karin J. \| Gulati, Abha \| Matin, Rubeta N. \| Romanowska, Malgorzata \| Cerio, Rino \| Kelsell, David P. \| Leigh, Irene M. \| Proby, Charlotte M. International Journal of Cancer, volume 131, issue 3 (2012). 10.1002/ijc.27333 Cited by (16) \| Cite \| Source \| Open Access
AKT1 Loss Correlates with Episomal HPV16 in Vulval Intraepithelial Neoplasia (journal article) Ekeowa-Anderson, Arucha L. \| Purdie, Karin J. \| Gibbon, Karen \| Byrne, Carolyn R. \| Arbeit, Jeffrey M. \| Harwood, Catherine A. \| O'Shaughnessy, Ryan F. L. PLoS ONE, volume 7, issue 6, pages e38608- (2012). 10.1371/journal.pone.0038608 Cited by (2) \| Cite \| Source \| Open Access