Alexander L. Satz

ScholarGPS® ID: 45483173141255

Affiliation

WuXi AppTec, China

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

1,717

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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DNA-Compatible Cyclization Reaction to Access 1,3,4-Oxadiazoles and 1,2,4-Triazoles (journal article) Wang, Gaonan \| Tan, Yu \| Zou, Hanzhi \| Sui, Xihang \| Wang, Zhanlong \| Satz, Alexander L. \| Kuai, Letian \| Su, Wenji \| Zhang, Qi Organic Letters, volume 26, issue 7, pages 1353-1357 (2024). 10.1021/acs.orglett.3c04240 Cited by (1) \| Cite \| Source
DNA-Encoded Macrocyclic Peptide Libraries Enable the Discovery of a Neutral MDM2–p53 Inhibitor (journal article) Silvestri, Anthony P. \| Zhang, Qi \| Ping, Yan \| Muir, Erik W. \| Zhao, Jingsi \| Chakka, Sai Kumar \| Wang, Gaonan \| Bray, Walter M. \| Chen, Wenhua \| Fribourgh, Jennifer L. \| ... \| Schwochert, Joshua A. ACS Medicinal Chemistry Letters, volume 14, issue 6, pages 820-826 (2023). 10.1021/acsmedchemlett.3c00117 Cited by (3) \| Cite \| Source
Assessment of AI-Based Protein Structure Prediction for the NLRP3 Target (journal article) Yin, Jian \| Lei, Junkun \| Yu, Jialin \| Cui, Weiren \| Satz, Alexander L. \| Zhou, Yifan \| Feng, Hua \| Deng, Jason \| Su, Wenji \| Kuai, Letian Molecules, volume 27, issue 18, pages 5797- (2022). 10.3390/molecules27185797 Cited by (7) \| Cite \| Source
Discovery of SARS-CoV-2 main protease covalent inhibitors from a DNA-encoded library selection (journal article) Ge, Rui \| Shen, Zuyuan \| Yin, Jian \| Chen, Wenhua \| Zhang, Qi \| An, Yulong \| Tang, Dewei \| Satz, Alexander L. \| Su, Wenji \| Kuai, Letian SLAS Discovery, volume 27, issue 2, pages 79-85 (2022). 10.1016/j.slasd.2022.01.001 Cited by (21) \| Cite \| Source
DNA-encoded chemical libraries (journal article) Satz, Alexander L. \| Brunschweiger, Andreas \| Flanagan, Mark E. \| Gloger, Andreas \| Hansen, Nils J. V. \| Kuai, Letian \| Kunig, Verena B. K. \| Lu, Xiaojie \| Madsen, Daniel \| Marcaurelle, Lisa A. \| ... \| Scheuermann, Jörg Nature Reviews Methods Primers, volume 2, issue 1 (2022). 10.1038/s43586-021-00084-5 Cited by (88) \| Cite \| Source
A History of Selection-Based High-Throughput Screening Technologies for Hit Identification (book chapter) In DNA-Encoded Libraries Kodadek, Thomas \| Satz, Alexander Springer International Publishing (2022) 10.1007/7355_2022_145 Cited by (1) \| Cite \| Source
Analysis of DNA-Encoded Library Screening Data: Selection of Molecules for Synthesis (book chapter) In DNA-Encoded Chemical Libraries Satz, Alexander L. \| Cui, Weiren Springer US (2022) 10.1007/978-1-0716-2545-3_23 Cite \| Source
Discovery of a Highly Selective BET BD2 Inhibitor from a DNA-Encoded Library Technology Screening Hit (journal article) Rianjongdee, Francesco \| Atkinson, Stephen J. \| Chung, Chun-wa \| Grandi, Paola \| Gray, James R. J. \| Kaushansky, Laura J. \| Medeiros, Patricia \| Messenger, Cassie \| Phillipou, Alex \| Preston, Alex \| ... \| Demont, Emmanuel H. Journal of Medicinal Chemistry, volume 64, issue 15, pages 10806-10833 (2021). 10.1021/acs.jmedchem.1c00412 Cited by (32) \| Cite \| Source
Triaging of DNA-Encoded Library Selection Results by High-Throughput Resynthesis of DNA–Conjugate and Affinity Selection Mass Spectrometry (journal article) Su, Wenji \| Ge, Rui \| Ding, Duanchen \| Chen, Wenhua \| Wang, Wenqing \| Yan, Hao \| Wang, Weikun \| Yuan, Youlang \| Liu, Huan \| Zhang, Meng \| ... \| Kuai, Letian Bioconjugate Chemistry, volume 32, issue 5, pages 1001-1007 (2021). 10.1021/acs.bioconjchem.1c00170 Cited by (19) \| Cite \| Source
Selections and screenings of DNA-encoded chemical libraries against enzyme and cellular targets (journal article) Satz, Alexander L. \| Kuai, Letian \| Peng, Xuanjia Bioorganic & Medicinal Chemistry Letters, volume 39 (2021). 10.1016/j.bmcl.2021.127851 Cited by (18) \| Cite \| Source
DNA‐Compatible Click Reaction Employing In Situ Generated Azides from Boronic Acids (journal article) An, Yulong \| Yan, Hao \| Dong, Zhenzhen \| Satz, Alexander L. Current Protocols, volume 1, issue 5 (2021). 10.1002/cpz1.125 Cited by (4) \| Cite \| Source
Synthesis of 1,2-Amino Alcohols by Photoredox-Mediated Decarboxylative Coupling of α-Amino Acids and DNA-Conjugated Carbonyls (journal article) Wen, Huanan \| Ge, Rui \| Qu, Yi \| Sun, Jialin \| Shi, Xiaodong \| Cui, Weiren \| Yan, Hao \| Zhang, Qi \| An, Yulong \| Su, Wenji \| ... \| Peng, Xuanjia Organic Letters, volume 22, issue 24, pages 9484-9489 (2020). 10.1021/acs.orglett.0c03461 Cited by (31) \| Cite \| Source
DNA-Encoded Libraries in the Pharmaceutical Industry (book chapter) In 2020 Medicinal Chemistry Reviews Satz, Alexander L. \| Kollman, Christopher S. \| Paegel, Brian M. Medicinal Chemistry Division of the American Chemical Society (2020) 10.29200/acsmedchemrev-v55.ch23 Cited by (1) \| Cite \| Source
Palladium-mediated Suzuki-Miyaura Cross-Coupling Reaction of Potassium Boc-protected aminomethyltrifluoroborate with DNA-Conjugated aryl bromides for DNA-Encoded chemical library synthesis (journal article) Qu, Yi \| Liu, Sixiu \| Wen, Huanan \| Xu, Yanfen \| An, Yulong \| Li, Ke \| Ni, Mengyuan \| Shen, Yanfang \| Shi, Xiaodong \| Su, Wenji \| ... \| Peng, Xuanjia Biochemical and Biophysical Research Communications, volume 533, issue 2, pages 209-214 (2020). 10.1016/j.bbrc.2020.04.027 Cited by (15) \| Cite \| Source
DNA-Compatible Copper-Catalyzed Oxidative Amidation of Aldehydes with Non-Nucleophilic Arylamines (journal article) Li, Ke \| Qu, Yi \| An, Yulong \| Breinlinger, Eric \| Webster, Matthew P. \| Wen, Huanan \| Ding, Duanchen \| Zhao, Meng \| Shi, Xiaodong \| Wang, Jiangong \| ... \| Peng, Xuanjia Bioconjugate Chemistry, volume 31, issue 9, pages 2092-2097 (2020). 10.1021/acs.bioconjchem.0c00392 Cited by (8) \| Cite \| Source
Bicyclic quinazolinone derivatives (patent) Hert, Jerome \| Hunziker, Daniel \| Kuratli, Christoph \| Martin, Rainer E. \| Mattei, Patrizio \| Satz, Alexander Lee Patent Number: 10676446 (2020) Cited by (2) \| Cite \| Source
Copper-Mediated DNA-Compatible One-Pot Click Reactions of Alkynes with Aryl Borates and TMS-N3 (journal article) Qu, Yi \| Wen, Huanan \| Ge, Rui \| Xu, Yanfen \| Gao, Hong \| Shi, Xiaodong \| Wang, Jiangong \| Cui, Weiren \| Su, Wenji \| Yang, Hongfang \| ... \| Peng, Xuanjia Organic Letters, volume 22, issue 11, pages 4146-4150 (2020). 10.1021/acs.orglett.0c01219 Cited by (25) \| Cite \| Source
Solution-Phase DNA-Compatible Pictet-Spengler Reaction Aided by Machine Learning Building Block Filtering (journal article) Li, Ke \| Liu, Xiaohong \| Liu, Sixiu \| An, Yulong \| Shen, Yanfang \| Sun, Qingxia \| Shi, Xiaodong \| Su, Wenji \| Cui, Weiren \| Duan, Zhiqiang \| ... \| Lu, Xiaojie iScience, volume 23, issue 6, pages 101142- (2020). 10.1016/j.isci.2020.101142 Cited by (15) \| Cite \| Source
Off-DNA DNA-Encoded Library Affinity Screening (journal article) Hackler, Amber L. \| FitzGerald, Forrest G. \| Dang, Vuong Q. \| Satz, Alexander L. \| Paegel, Brian M. ACS Combinatorial Science, volume 22, issue 1, pages 25-34 (2020). 10.1021/acscombsci.9b00153 Cited by (31) \| Cite \| Source
Solution Phase DNA-Compatible Pictet-Spengler Reaction Aided by Machine Learning Building Block Filtering (journal article) Li, Ke \| Liu, Xiaohong \| Liu, Sixiu \| An, Yulong \| Shen, Yanfang \| Sun, Qingxia \| Shi, Xiaodong \| Su, Wenji \| Cui, Weiren \| Duan, Zhiqiang \| ... \| Lu, Xiaojie SSRN Electronic Journal (2020). 10.2139/ssrn.3529715 Cite \| Source