Ornella Franzese

ScholarGPS® ID: 44915780783630

Affiliation

University of Rome Tor Vergata, Rome, Italy

Affiliation History

Field

Medicine

Discipline

Surgery

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

2,254

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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ADA/CD26 axis increases intra-tumor PD-1+ CD28+ CD8+ T-cell fitness and affects NSCLC prognosis and response to ICB (journal article) Franzese, Ornella \| Palermo, Belinda \| Frisullo, Giuseppe \| Panetta, Mariangela \| Campo, Giulia \| D’Andrea, Daniel \| Sperduti, Isabella \| Taje, Riccardo \| Visca, Paolo \| Nisticò, Paola OncoImmunology, volume 13, issue 1 (2024). 10.1080/2162402X.2024.2371051 Cite \| Source
Apoptosis, a Metabolic “Head-to-Head” between Tumor and T Cells: Implications for Immunotherapy (journal article) Franzese, Ornella \| Ancona, Pietro \| Bianchi, Nicoletta \| Aguiari, Gianluca Cells, volume 13, issue 11, pages 924- (2024). 10.3390/cells13110924 Cite \| Source
CD28/PD1 co-expression: dual impact on CD8+ T cells in peripheral blood and tumor tissue, and its significance in NSCLC patients' survival and ICB response (journal article) Palermo, Belinda \| Franzese, Ornella \| Frisullo, Giuseppe \| D’Ambrosio, Lorenzo \| Panetta, Mariangela \| Campo, Giulia \| D’Andrea, Daniel \| Sperduti, Isabella \| De Nicola, Francesca \| Goeman, Frauke \| ... \| Nisticò, Paola Journal of Experimental & Clinical Cancer Research, volume 42, issue 1 (2023). 10.1186/s13046-023-02846-3 Cited by (5) \| Cite \| Source
T-cell repertoire diversity: friend or foe for protective antitumor response? (journal article) Porciello, Nicla \| Franzese, Ornella \| D’Ambrosio, Lorenzo \| Palermo, Belinda \| Nisticò, Paola Journal of Experimental & Clinical Cancer Research, volume 41, issue 1 (2022). 10.1186/s13046-022-02566-0 Cited by (13) \| Cite \| Source
Role of PARP Inhibitors in Cancer Immunotherapy: Potential Friends to Immune Activating Molecules and Foes to Immune Checkpoints (journal article) Franzese, Ornella \| Graziani, Grazia Cancers, volume 14, issue 22, pages 5633- (2022). 10.3390/cancers14225633 Cited by (10) \| Cite \| Source
Abscopal Effect and Drug-Induced Xenogenization: A Strategic Alliance in Cancer Treatment? (journal article) Franzese, Ornella \| Torino, Francesco \| Giannetti, Elisa \| Cioccoloni, Giorgia \| Aquino, Angelo \| Faraoni, Isabella \| Fuggetta, Maria Pia \| De Vecchis, Liana \| Giuliani, Anna \| Kaina, Bernd \| Bonmassar, Enzo International Journal of Molecular Sciences, volume 22, issue 19, pages 10672- (2021). 10.3390/ijms221910672 Cited by (6) \| Cite \| Source
hTERT Transduction Extends the Lifespan of Primary Pediatric Low-Grade Glioma Cells While Preserving the Biological Response to NGF (journal article) Franzese, Ornella \| Di Francesco, Angela M. \| Meco, Daniela \| Graziani, Grazia \| Cusano, Gabriella \| Levati, Lauretta \| Riccardi, Riccardo \| Ruggiero, Antonio Pathology and Oncology Research, volume 27 (2021). 10.3389/pore.2021.612375 Cited by (5) \| Cite \| Source
Fatty acid synthase inhibitor orlistat impairs cell growth and down-regulates PD-L1 expression of a human T-cell leukemia line (journal article) Cioccoloni, Giorgia \| Aquino, Angelo \| Notarnicola, Maria \| Caruso, Maria Gabriella \| Bonmassar, Enzo \| Zonfrillo, Manuela \| Caporali, Simona \| Faraoni, Isabella \| Villivà, Cristina \| Fuggetta, Maria Pia \| Franzese, Ornella Journal of Chemotherapy, volume 32, issue 1, pages 30-40 (2020). 10.1080/1120009X.2019.1694761 Cited by (21) \| Cite \| Source
Antigen-specificity and DTIC before peptide-vaccination differently shape immune-checkpoint expression pattern, anti-tumor functionality and TCR repertoire in melanoma patients (journal article) Palermo, Belinda \| Franzese, Ornella \| Donna, Cosmo Di \| Panetta, Mariangela \| Quintarelli, Concetta \| Sperduti, Isabella \| Gualtieri, Novella \| Foddai, Maria Laura \| Proietti, Enrico \| Ferraresi, Virginia \| ... \| Nisticò, Paola OncoImmunology, volume 7, issue 12, pages e1465163- (2018). 10.1080/2162402X.2018.1465163 Cited by (6) \| Cite \| Source
Distinct Hypericum perforatum L. total extracts exert different antitumour activity on erythroleukemic K562 cells (journal article) Valletta, Elena \| Rinaldi, Annamaria \| Marini, Mario \| Franzese, Ornella \| Roscetti, Gianna Phytotherapy Research, volume 32, issue 9, pages 1803-1811 (2018). 10.1002/ptr.6114 Cited by (8) \| Cite \| Source
Drug-induced xenogenization of tumors: A possible role in the immune control of malignant cell growth in the brain? (journal article) Franzese, Ornella \| Battaini, Fiorenzo \| Graziani, Grazia \| Tentori, Lucio \| Barbaccia, Maria Luisa \| Aquino, Angelo \| Roselli, Mario \| Fuggetta, Maria Pia \| Bonmassar, Enzo \| Torino, Francesco Pharmacological Research, volume 131 (2018). 10.1016/j.phrs.2018.03.005 Cited by (5) \| Cite \| Source
Beneficial and Detrimental Effects of Antiretroviral Therapy on HIV-Associated Immunosenescence (journal article) Franzese, Ornella \| Barbaccia, Maria Luisa \| Bonmassar, Enzo \| Graziani, Grazia Chemotherapy, volume 63, issue 2, pages 64-75 (2018). 10.1159/000487534 Cited by (9) \| Cite \| Source
Tumor immunotherapy: drug-induced neoantigens (xenogenization) and immune checkpoint inhibitors (journal article) Franzese, Ornella \| Torino, Francesco \| Fuggetta, Maria Pia \| Aquino, Angelo \| Roselli, Mario \| Bonmassar, Enzo \| Giuliani, Anna \| D’Atri, Stefania Oncotarget, volume 8, issue 25, pages 41641-41669 (2017). 10.18632/oncotarget.16335 Cited by (16) \| Cite \| Source \| Open Access
Polyfunctional Melan-A-specific tumor-reactive CD8+ T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS (journal article) Franzese, Ornella \| Palermo, Belinda \| Di Donna, Cosmo \| Sperduti, Isabella \| Ferraresi, Virginia \| Stabile, Helena \| Gismondi, Angela \| Santoni, Angela \| Nisticò, Paola OncoImmunology, volume 5, issue 5, pages e1114203- (2016). 10.1080/2162402X.2015.1114203 Cited by (22) \| Cite \| Source \| Open Access
‘PD-1 related effector functions rely on the presence/absence of CD28 co-stimulatory molecule in Ag-specific CD8+ T cell clones isolated from melanoma patients’ (journal article) Palermo, Belinda \| Franzese, Ornella \| Di Donna, Cosmo \| Panetta, Mariangela \| Gualtieri, Novella \| Soriani, Antonella \| Foddai, Maria Laura \| Santoni, Angela \| Nisticò, Paola The Journal of Immunology, volume 196, issue 1_Supplement, pages 213.15-213.15 (2016). 10.4049/jimmunol.196.Supp.213.15 Cite \| Source
Resistance to the atypical retinoid ST1926 in SK-N-AS cells selected the subline rAS-ST with enhanced sensitivity to ATRA mediated by not conventional mechanisms: DNA damage, G2 accumulation and late telomerase inhibition (journal article) Di Francesco, A.M. \| Cusano, G. \| Franzese, O. \| Orienti, I. \| Falconi, M. \| Vesci, L. \| Riccardi, R. Toxicology in Vitro, volume 29, issue 7, pages 1628-1638 (2015). 10.1016/j.tiv.2015.06.017 Cited by (4) \| Cite \| Source
p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8+ T cells (journal article) Henson, Sian M. \| Lanna, Alessio \| Riddell, Natalie E. \| Franzese, Ornella \| Macaulay, Richard \| Griffiths, Stephen J. \| Puleston, Daniel J. \| Watson, Alexander Scarth \| Simon, Anna Katharina \| Tooze, Sharon A. \| Akbar, Arne N. Journal of Clinical Investigation, volume 124, issue 9, pages 4004-4016 (2014). 10.1172/JCI75051 Cited by (269) \| Cite \| Source \| Open Access
Defect in HSP90 expression in highly differentiated human CD8+ T lymphocytes (journal article) Franzese, O \| Henson, S M \| Naro, C \| Bonmassar, E Cell Death & Disease, volume 5, issue 6, pages e1294-e1294 (2014). 10.1038/cddis.2014.259 Cited by (7) \| Cite \| Source \| Open Access
The antiretroviral agent saquinavir enhances hTERT expression and telomerase activity in human T leukaemia cells in vitro (journal article) Adamo, Riccardo \| Comandini, Alessandro \| Aquino, Angelo \| Bonmassar, Laura \| Guglielmi, Loredana \| Bonmassar, Enzo \| Franzese, Ornella Journal of Experimental & Clinical Cancer Research, volume 32, issue 1 (2013). 10.1186/1756-9966-32-38 Cited by (11) \| Cite \| Source \| Open Access
IFN-α Inhibits Telomerase in Human CD8+ T Cells by Both hTERT Downregulation and Induction of p38 MAPK Signaling (journal article) Lanna, Alessio \| Coutavas, Elias \| Levati, Lauretta \| Seidel, Judith \| Rustin, Malcolm H. A. \| Henson, Sian M. \| Akbar, Arne N. \| Franzese, Ornella The Journal of Immunology, volume 191, issue 7, pages 3744-3752 (2013). 10.4049/jimmunol.1301409 Cited by (45) \| Cite \| Source \| Open Access